Current Cell Division News and Events | Page 25

Current Cell Division News and Events, Cell Division News Articles.
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'Parent' cells reset the cell division clock
Melbourne researchers have overturned a 40-year-old theory on when and how cells divide, showing that 'parent' cells program a cell division time for their offspring that is different from their own. (2014-05-08)

Why a bacterium got its curve -- and why biologists should know
Princeton University researchers found that the banana-like curve of the bacteria Caulobacter crescentus provides stability and helps them flourish as a group in the moving water they experience in nature. The findings suggest a new way of studying the evolution of bacteria that emphasizes using naturalistic settings. (2014-05-08)

Discovery that heart cells replicate during adolescence opens new avenue for heart repair
It is widely accepted that heart muscle cells in mammals stop replicating shortly after birth, limiting the ability of the heart to repair itself after injury. A new study shows that heart muscle cells in mice undergo a burst prior to adolescence to allow for a period of rapid growth. The findings suggest that thyroid hormone therapy could stimulate this process and enhance the heart's ability to regenerate in patients with heart disease. (2014-05-08)

Spurt of heart muscle cell division seen in mice well after birth
The entire heart muscle in young children may be capable of regeneration. In young mice 15 days old, cardiac muscle cells undergo a precisely timed spurt of cell division lasting around a day. This previously unobserved phenomenon contradicts the long-held idea that cardiac muscle cells do not divide after the first few days of life. (2014-05-08)

Kaiser Permanente study finds radiation best treatment for a rare skin cancer
Radiation treatment can help reduce the recurrence of Merkel cell carcinoma, a rare and aggressive skin cancer, while chemotherapy does not appear to have any impact on recurrence or survival, according to a Kaiser Permanente study published online in the current issue of JAMA Dermatology. (2014-05-07)

Scientists link honeybees' changing roles throughout their lives to brain chemistry
Scientists have been linking an increasing range of behaviors and inclinations from monogamy to addiction to animals', including humans', underlying biology. To that growing list, they're adding division of labor -- at least in killer bees. A report published in ACS' Journal of Proteome Research presents new data that link the amounts of certain neuropeptides in these notorious bees' brains with their jobs inside and outside the hive. (2014-05-07)

St. Jude Children's Research Hospital scientist elected to National Academy of Sciences
Brenda Schulman, Ph.D., of St. Jude Children's Research Hospital, has been elected to the National Academy of Sciences. (2014-05-01)

DNA repair gene provides new ideas for disease treatment
A gene known to repair DNA damage in healthy cells may also provide new insights about treating a genetic disorder of the bone marrow, Caltech researchers say. (2014-04-30)

Function found for mysterious heart disease gene
A new study from researchers at the University of Ottawa Heart Institute (UOHI), published today in Cell Reports, sheds light on a mysterious gene that likely influences cardiovascular health. After five years, UOHI researchers now know how one genetic variant works and suspect that it contributes to the development of heart disease through processes that promote chronic inflammation and cell division. (2014-04-25)

Scientists find way to target cells resistant to chemo
Scientists from The University of Manchester have identified a way to sensitize cancer cells to chemotherapy -- making them more open to treatment. (2014-04-24)

Hundreds of genetic mutations found in healthy blood of a supercentenarian
Genetic mutations are commonly studied because of links to diseases such as cancer; however, little is known about mutations occurring in healthy individuals. In a study published online in Genome Research, researchers detected over 400 mutations in healthy blood cells of a 115-year-old woman, suggesting that lesions at these sites are largely harmless over the course of a lifetime. (2014-04-23)

Study identifies enzymes that help fix cancer-causing DNA defects
Purdue University researchers have identified an important enzyme pathway that helps prevent new cells from receiving too many or too few chromosomes, a condition that has been directly linked to cancer and other diseases. (2014-04-23)

Cancer stem cells linked to drug resistance
Most drugs used to treat lung, breast and pancreatic cancers also promote drug-resistance and ultimately spur tumor growth. Researchers at the University of California, San Diego School of Medicine have discovered a molecule, or biomarker, called CD61 on the surface of drug-resistant tumors that appears responsible for inducing tumor metastasis by enhancing the stem cell-like properties of cancer cells. (2014-04-20)

Surprise: Lost stem cells naturally replaced by non-stem cells, fly research suggests
Johns Hopkins researchers have discovered an unexpected phenomenon in the organs that produce sperm in fruit flies: When a certain kind of stem cell is killed off experimentally, another group of non-stem cells can come out of retirement to replace them. (2014-04-17)

Dual role: Key cell division proteins also power up mitochondria
An international team led by researchers at UC Davis has shown that the cyclin B1/Cdk1 protein complex, which plays a key role in cell division, also boosts the mitochondrial activity to power that process. (2014-04-17)

For cells, internal stress leads to unique shapes
Caltech researchers discover that a cell's unique shape results from an internal tug-of-war: the cell needs to maintain structural integrity while also dynamically responding to the pushes and pulls of mechanical stress. (2014-04-16)

At the origin of cell division
Movement and the ability to divide are two fundamental traits of living cells. The origin of these abilities could rely on very simple physical mechanisms, which have been simulated by scientists of the International School for Advanced Studies of Trieste in a study just published in Physical Review Letters. Luca Giomi and Antonio DeSimone have reproduced motility in their models, by acting on a single parameter until they caused the 'cells' to divide spontaneously without the action of external forces. (2014-04-16)

Breaking bad mitochondria
Researchers at the University of California, San Diego School of Medicine have identified a mechanism that explains why people with the hepatitis C virus get liver disease and why the virus is able to persist in the body for so long. (2014-04-15)

TGen identifies growth factor receptors that may prompt metastatic spread of lung cancer
Two cell surface receptors might be responsible for the most common form of lung cancer spreading to other parts of the body, according to a study by the Translational Genomics Research Institute. The hepatocyte growth factor receptor and fibroblast growth factor-inducible 14 are proteins associated with the potential spread of non-small cell lung cancer, according to the TGen study published online April 8 by the scientific journal Clinical & Experimental Metastasis. (2014-04-09)

Breast cancer cell subpopulation cooperation can spur tumor growth
Sub-populations of breast cancer cells sometimes cooperate to aid tumor growth, according to Penn State College of Medicine researchers, who believe that understanding the relationship between cancer sub-populations could lead to new targets for cancer treatment. (2014-04-08)

Kinesin-5 structure opens cancer drug targets
The structure of a key part of the machinery that allows cells to divide has been identified by researchers at UC Davis -- opening new possibilities for throwing a wrench in the machine and blocking runaway cell division in cancer. (2014-04-08)

Study examines biomarkers in HPV negative squamous-cell carcinomas of the head and neck
A quartet of proteins that play critical roles in cell replication, cell death and DNA repair could lead to better targets for therapy against treatment-resistant head-and-neck squamous cell cancers. (2014-04-08)

Zombie cancer cells eat themselves to live
A University of Colorado Cancer Center study recently published in the journal Cell Reports and presented today at the American Association for Cancer Research Annual Conference 2014 shows that the cellular process of autophagy in which cells 'eat' parts of themselves in times of stress may allow cancer cells to recover and divide rather than die when faced with chemotherapies. (2014-04-05)

Combining cell replication blocker with common cancer drug kills resistant tumor cells
Researchers from the University of Pittsburgh Cancer Institute, a partner with UPMC CancerCenter, have found that an agent that inhibits mitochondrial division can overcome tumor cell resistance to a commonly used cancer drug, and that the combination of the two induces rapid and synergistic cell death. Separately, neither had an effect. These findings will be presented Monday at the annual meeting of the American Association for Cancer Research Annual Meeting 2014. (2014-04-04)

Discovery of a mechanism that makes tumor cells sugar addicted
For almost a hundred years ago is known that cancer cells feel a special appetite for a type of sugar called glucose. The tumor uses this molecule is like the gasoline which depends a sports car to burn faster and grows and multiplies rapidly. It is a little cash process from the energy point of view but allows a superaccelerated cancer cell division. It is what is known as the Warburg effect, which was described in 1927. (2014-04-03)

Going global
In textbooks, the grand finale of cell division is the tug-of-war fought inside dividing cells as duplicated pairs of chromosomes get dragged in opposite directions into daughter cells. This process, called mitosis, is visually stunning to observe under a microscope. Equally stunning to cell biologists are the preparatory steps cells take to ensure that the process occurs safely. (2014-04-02)

Professor Jerry Adams inducted to American cancer academy
Walter and Eliza Hall Institute cancer researcher professor Jerry Adams has been elected a fellow of the academy established by the American Association for Cancer Research. Professor Adams was the only Australian researcher to be selected as a fellow in 2014. The academy will welcome 38 new fellows at the AACR annual meeting in San Diego, US, on Friday, April 4, 2014. (2014-04-01)

UCLA scientist awarded $3 million to fund research into proteins affecting the kidney
UCLA scientist Dr. Ira Kurtz has received a $3 million gift from the Donald T. Sterling Foundation to fund research on the structural properties of key proteins in the kidney that affect its function. (2014-04-01)

Newly discovered molecule may offer hope for immune disorders and runaway inflammation
A new research discovery published in the Journal of Leukocyte Biology may open the door to new therapies that help treat immune disorders or curb runaway inflammation. Specifically, scientists have discovered a molecule that can induce cell death (apoptosis) in a key type of immune cell (dendritic cells). With this understanding, it may be possible to develop new therapies that essentially shut down dendritic cell activity, and thereby reducing an immune reaction. (2014-03-31)

How size splits cells
Contrary to previous findings suggesting a protein measures cell length, a different protein is found to measure the cell's surface area. (2014-03-26)

Kif15: The acrobatic motor protein that could pave the way for new cancer therapies
Researchers at Warwick Medical School have shown for the first time how a protein motor, Kif15, uses acrobatic flexibility to navigate within the mitotic spindle. Understanding how it works could prove vital for the development of targeted cancer therapies. (2014-03-26)

New technique for identifying gene-enhancers
Berkeley Lab researchers led the development of a new technique for identifying gene enhancers -- sequences of DNA that act to amplify the expression of a specific gene -- in the genomes of humans and other mammals. Called SIF-seq, this new technique complements existing genomic tools, such as ChIP-seq, and offers additional benefits. (2014-03-24)

A study using Drosophila flies reveals new regulatory mechanisms of cell migration
A study by Sofia J. Araujo, a Ramon y Cajal researcher with the Morphogenesis in Drosophila lab at the Institute for Research in Biomedicine, provides new insights into the genetic regulation of cell migration. Published today in the scientific journal PLOS ONE, the research is part of the thesis work performed by Elisenda Buti, first author of the article. (2014-03-21)

Cells do not repair damage to DNA during mitosis because telomeres could fuse together
Throughout a cell's life, corrective mechanisms act to repair DNA strand breaks. The exception is during the critical moment of cell division, when chromosomes are most vulnerable. Toronto researchers found out why DNA repair shuts down during mitosis. (2014-03-20)

New understanding of why chromosome errors are high in women's eggs
A new study from the University of Southampton has provided scientists with a better understanding of why chromosome errors are high in women's eggs. (2014-03-18)

Study finds that fast-moving cells in the human immune system walk in a stepwise manner
A team of biologists and engineers at UC San Diego applied advanced mathematical tools to answer a basic question in cell biology about how cells move and discovered that the mechanism looks very similar to walking. Their discovery, published March 17 in the Journal of Cell Biology, is an important advance toward developing new pharmacological strategies to treat chronic inflammatory diseases. (2014-03-17)

Anti-psychotic medications offer new hope in the battle against glioblastoma
Researchers at the University of California, San Diego School of Medicine have discovered that Food and Drug Administration-approved anti-psychotic drugs possess tumor-killing activity against the most aggressive form of primary brain cancer, glioblastoma. (2014-03-07)

Researchers capture 'most complete' picture of gene expression in cancer cell cycle
Uncontrolled cell growth and division is a hallmark of cancer. Now a research project led by the University of Dundee has provided the most complete description to date of the gene activity which takes place as human cells divide. (2014-03-06)

Testis size matters for genome evolution
In the advanced online edition of Molecular Biology and Evolution, author Alex Wong used a published sequence dataset from 55 species of primates to test for a correlation between molecular evolutionary rates across a genome (substitution rates) and testes weights, used in the study as a proxy for increased sperm production and competition. (2014-03-05)

New findings on neurogenesis in the spinal cord
Research from Karolinska Institutet in Sweden suggests that the expression of the so-called MYC gene is important and necessary for neurogenesis in the spinal cord. The findings are being published in the journal EMBO Reports. (2014-03-05)

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