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Institute for OneWorld Health CEO speaks at 2005 World Life Sciences Forum, BioVision
Victoria Hale, Ph.D., CEO and Founder of the Institute for OneWorld Health will provide perspectives on drug and vaccine development from a nonprofit pharmaceutical company's viewpoint at two events at BioVision, April 10-15 in Lyon, France. The biannual event of the World Life Sciences Forum fosters debate and exchange among representatives from science, society, and industry. OneWorld Health will also exhibit at BioVision, booth R24. (2005-04-04)

New hope for Chagas disease treatment
Until now, there has been no effective treatment for chronic Chagas disease, which kills up to one-third of those infected, usually by heart failure. Now two HHMI international research scholars from Venezuela and Argentina have found that TAK-187, a drug patented as a systemic anti-fungal, is more effective with fewer side effects in mice than benznidazole, the current standard of care. (2005-03-31)

Institute for OneWorld Health awarded Skoll Foundation's Social Entrepreneurship Award
The Institute for OneWorld Health today announced that it has been awarded a 2005 Skoll Award for Social Entrepreneurship in the amount of $615,000 over three years. Based in San Francisco, OneWorld Health is the first nonprofit pharmaceutical company in the U.S. and develops new medicines to cure infectious diseases that disproportionately affect the poorest people in the world. (2005-03-21)

NHGRI targets 12 more organisms for genome sequencing
The National Human Genome Research Institute (NHGRI), one of the National Institutes of Health (NIH), announced today that the Large-Scale Sequencing Research Network will begin sequencing 12 more strategically selected organisms, including the marmoset, a skate and several important insects, as part of its ongoing effort to expand understanding of the human genome. (2005-03-01)

High resolution satellite imagery assists hunt for infectious 'kissing bugs'
In the midst of crammed slums in the Nicaraguan district of Matagalpa, aid workers are hunting house-to-house for hidden killers, their search guided by high-resolution satellite imagery supplied through an ESA-backed project. (2004-09-28)

Call for investment in prevention of 'neglected diseases' to improve global health
The author of a Viewpoint article in this week's issue of The Lancet argues for a renewed public-health effort to tackle so-called 'neglected diseases' which continue to have serious impact in less-developed countries. (2004-07-21)

Call for investment in prevention of 'neglected diseases' to improve global health
The author of a Viewpoint article published online by The Lancet argues for a renewed public-health effort to tackle so-called 'neglected diseases' which continue to have serious impact in less-developed countries. (2004-07-12)

HHMI commits more than $30 million to help reverse brain drain, beat infectious diseases
Howard Hughes Medical Institute is stepping up its commitment to fostering international biomedical research with two new competitions for more than $30 million in research grants to biomedical scientists outside the United States. One targets infectious diseases and parasitology research. The other is for scientists in Central and Eastern Europe, the Baltics, Russia and Ukraine. (2004-04-14)

OneWorld Health plans to form network of volunteer pharmaceutical scientists for global health
The Institute for OneWorld Health, the first non-profit pharmaceutical company in the U.S., today announced its intent to develop a volunteer network of corporate and industry pharmaceutical scientists that would promote development of medicines for neglected diseases. The news was announced upon receipt of a grant from the Sapling Foundation (Woodside, Calif.), which will provide seed funding to initiate development of the community of volunteer scientists. (2004-03-30)

Nonprofit pharmaceutical seeks drug approval next year
The Institute for OneWorld Health announced it is only a year away from seeking approval for paromomycin, its first medicine, a drug to cure a deadly parasitic disease in India. Founder and CEO Victoria Hale, Ph.D. made the announcement at last week's World Economic Forum in Davos, Switzerland, where she was a panelist in a roundtable discussion, (2004-01-26)

Pew report finds GM insects may offer benefits, but clear regulatory oversight is lacking
Researchers are using biotechnology to develop genetically modified insects for a wide variety of purposes, including fighting insect-borne diseases like malaria and controlling destructive insect agricultural pests, but the federal government lacks a clear regulatory framework for reviewing environmental safety and other issues associated with GM insects, according to Bugs in the System? Issues in the Science and Regulation of Genetically Modified Insects, a new report released by the Pew Initiative on Food and Biotechnology. (2004-01-22)

Chagas' disease: virulence factor identified
Chagas' disease affects over 18 million people in Latin America. The agent responsible is a protozoan parasite, Trypanosoma cruzi, transmitted by haematophagous insects. IRD and INSERM (1) searchers found that this trypanosome secretes a protein Tc52 that is a virulence factor. They found its role in the development of infection and performed the molecular characterization by peptide analysis of the minimal sequence of Tc52 that carries immunosuppressive activity. This raises the prospects for developing vaccination strategies or drugs to combat T. cruzi. (2004-01-06)

Victoria Hale of Institute for OneWorld Health Named Fellow by International Women's Forum
The Institute for OneWorld Health, the first nonprofit pharmaceutical company in the United States, today announced that CEO Victoria Hale, Ph.D., has been named a Leadership Foundation Fellow for 2003-2004. Hale is one of 14 women selected from a field of more than 50 finalists from all over the world. OneWorld Health's experienced team of pharmaceutical scientists uncovers promising drug candidates and advances them through clinical trials and regulatory approval to treat the poorest people in the developing world. (2003-09-15)

OneWorld Health licenses compounds from Yale, U of Washington to treat major parasitic diseases
The Institute for OneWorld Health has licensed highly potent azole compounds from Yale and the University of Washington that could result in new medicines for parasitic diseases, initially for Chagas, in the developing world, and new antifungals for the developed world. The compounds broaden OneWorld Health's product portfolio for Chagas disease, which afflicts up to 18 million people in Latin America, and at least 50,000 to 100,000 in the U.S. The license also creates a unique dual market opportunity. (2003-07-08)

A little blue and purple helps body fend off deadly parasites
Chagas disease, a parasitic disease that is nearly epidemic from Mexico to Tierra del Fuego, may have met its match in a simple solution of dyes, a UC Irvine study has found. (2002-10-15)

Scientists decipher genetic code of malaria parasite
In a landmark contribution to the age-old battle against malaria, a consortium of scientists including The Institute for Genomic Research (TIGR) announced today that they have deciphered the complex genetic code of the parasite that causes the deadliest form of the disease. Malaria is one of the world's most devastating infectious diseases, killing more than a million people a year in developing nations. (2002-10-02)

Vitex reports parasite inactivation results at ISBT 2002
V.I. Technologies, Inc. (Vitex) (Nasdaq: VITX), a biotechnology company dedicated to developing products that improve the safety and availability of the transfusion blood supply by pathogen reduction or removal, reported today at ISBT 2002 that its INACTINETM technology was successful in eradicating the parasites that cause Chagas' Disease, malaria and babesiosis in red blood cells. The company also presented its overall clinical development program for INACTINETM red blood cells including results of completed clinical trials. (2002-08-26)

Diagnostic kit for Chagas' disease rewarded by the Altran Foundation
Eric Deharo, biologist and pharmacologist at the Institut de Recherche Pour le Développement (IRD), working in Bolivia, has just received a special mention from the Altran Foundation (Altran Technologie) jury for his diagnostic kit for Chagas' disease in the context of the 2002 awards (2002-07-08)

New center to study deadly microbial pathogens
The Keck Center for Functional, Structural, and Chemical Genomics of Microbial Pathogens will unite 20 UW faculty to exploit the full medical potential of existing and forthcoming microbial genome sequences. In addition, the Keck Center will attract new faculty in the areas of mass spectrometry, crystallography, and proteomics. In the United States, the rate of deaths caused by infectious disease has grown from 36 per 100,000 in 1981 to at least 63 per 100,000. (2002-03-06)

Researchers' mathematical model provides chagas disease insights
A mathematical model indicates that the chronic, frequently fatal Chagas disease could be greatly reduced in humans by barring domestic animals from bedrooms. Reporting in the July 27 edition of Science, Joel E. Cohen, head of the Laboratory of Populations at The Rockefeller University , and Ricardo E. Gürtler of the University of Buenos Aires predicted how four populations--bugs, chickens, dogs and people--affect T. cruzi transmission in an individual household. (2001-07-25)

Banning animals from the bedroom could reduce Chagas Disease risk, say Science researchers
Keeping domesticated animals out of bedrooms could help reduce the risk of deadly Chagas disease infection in rural areas of Central and South America, according to a new report in the 27 July issue of the international journal, Science. (2001-07-23)

Concern over safety of yellow fever vaccine
Seven severe cases of illness - including 6 deaths - after yellow-fever vaccination are described in two articles and one research letter in this week's issue of THE LANCET. Although these reports call into question the safety of yellow-fever vaccination, the overall conclusion to be drawn is that vaccination programmes should be continued, with the need for new research to explain how some individuals can become sensitised to yellow-fever vaccine. (2001-07-12)

NIAID events highlight global health research
On Monday, May 7, NIAID hosts 2 events: it will announce its Global Health Research Plan for HIV/AIDS, Malaria, and Tuberculosis during the 10th anniversary ICTDR meeting, and it will hold a 2:00 p.m. grand opening ceremony for its new Malaria Vaccine Development Unit. (2001-04-25)

Osteoporosis drugs found to combat malaria, other diseases
A series of bisphosphonate drugs already approved to treat osteoporosis and other bone disorders in humans carry potent anti-parasitic activity, offering a new approach to the treatment of malaria, sleeping sickness and AIDS-related infections such as toxoplasmosis. (2001-02-28)

American Society for Tropical Medicine and Hygiene holds annual meeting in Houston, October 29-November 2
Media representatives are invited to attend the 49th Annual Meeting of the American Society for Tropical Medicine and Hygiene, October 29th-November 2, 2000, at the Western Galleria and Oaks Hotel, Houston, Texas. (2000-09-24)

HHMI awards $15 million to scientists outside United States
The Howard Hughes Medical Institute has awarded $15 million in grants to help scientists outside the United States develop new approaches to overcoming malaria, tuberculosis, Chagas disease, Lassa fever, amebiasis and other infectious and parasitic diseases. (2000-07-25)

'Kissing bug' researcher to speak at world's largest scientific society meeting
Dr. F. Ann Walker of the University of Arizona will present award-winning research about the kissing bug and how it transmits the deadly Chagas' disease. Walker will address women chemists at the 219th meeting of the American Chemical Society, the world's largest scientific society. (2000-03-19)

Health In The Americas Is Improving, PAHO Report Says
The health of people in the Americas is improving, thanks to progress in the fight against infectious disease, increased access to clean drinking water, and declines in the death rates among infants and young children, the Pan American Health Organization (PAHO) reports. (1998-09-21)

PAHO Details Successes In Fight Against Communicable Diseases
The Western Hemisphere contains roughly half the number of people in the world known to have AIDS, but epidemiologists are concerned that the true number of people infected with the virus that causes the disease may be twice as high as current estimates, the Pan American Health Organization reports. (1998-09-21)

New Class Of Protease Inhibitors May Be Effective In Treating One Of Latin America's Most Devastating Diseases
Researchers at the San Francisco Veterans Affairs Medical Center and UC San Francisco have demonstrated that a type of drug known as a cysteine protease inhibitor may be highly effective against American trypanosomiasis or Chagas1 disease, which is caused by an infection with the parasite Trypansoma cruzi (T. cruzi). (1998-08-18)

NASA Research Helps Map Protein Structures -- Key In The Development Of New Disease-Fighting Drugs
Research sponsored by NASA's Microgravity Research Program at Marshall Space Flight Center in Huntsville, Alabama, is making significant contributions to scientists' understanding of the molecular structure of living things - a key to the development of new disease-fighting drugs. (1998-07-21)

Infectious And Parasitic Diseases Still Threaten World Health
More than 17 million people were killed by infectious and parasitic diseases last year, and most could have been avoided, according to a new report co-written at Argonne National Laboratory (1997-09-17)

Heart Problems In Victims Of Tropical Disease May Not Be Caused By Autoimmune Reaction; New Treatment Indicated
New evidence by scientists from the University of Georgia indicates that victims of a common tropical disease may be receiving inadequate treatment because of a major misunderstanding of how the disease progresses. (1997-09-04)

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