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A new view of microscopic interactions
When two cars collide at an intersection -- from opposite directions -- the impact is much different than when two cars -- traveling in the same direction -- 'bump' into each other. In the laboratory, similar types of collisions can be made to occur between molecules to study chemistry at very low temperatures, or 'cold collisions.' A team of scientists led by Arthur Suits at the University of Missouri has developed a new experimental approach to study chemistry using these cold 'same direction' molecular collisions. (2020-06-30)

Wrapping up hydrophobic hydration
Studied in detail, the embedding of hydrophobic molecules in water looks quite different than previously assumed. (2020-06-29)

Scientists propose strategy for site-selective chiral drug synthesis in living systems
Prof. QU Xiaogang from the Changchun Institute of Applied Chemistry (CIAC) of the Chinese Academy of Sciences and his colleagues recently presented a novel strategy using a neutrophil-directed ATH reaction to achieve site-selective chiral drug synthesis in living systems. (2020-06-26)

Breaking the limit
University of Freiburg researchers introduce new transition metal carbonyl complexes relevant to textbooks and applications (2020-06-23)

Support drives fate of protected gold nanoclusters as catalysts
In collaboration with experimentalists from Ghent University, Belgium and Utrecht University, Netherlands, researchers at the Nanoscience Center (NSC) at the University of Jyväskylä, have recently discovered that the choice of a support material for model catalysts, made from gold nanoclusters protected by organic molecules, may have drastic effects on the structure of the catalyst. (2020-06-16)

Novel noncovalent bond blocks repulsive odor of isocyanides
Researchers at St. Petersburg State University have developed a method for eliminating the overpoweringly unpleasant odor of isocyanides, an important class of organic compounds. (2020-06-11)

Minority students can become 'hyperpersistent' when they achieve better than middling grades
Scientists report that undergraduate students from underrepresented groups who score below a C- in general chemistry are less likely to persist in STEM classes than their classmates with similar grades, but they are much more likely than their peers to persist if they earn a C+ or better. The researchers suggest that improving the performance of all students could (2020-06-10)

Innocent and highly oxidizing
Freiburg chemists produce new oxidants as a tool for preparative chemistry (2020-06-03)

CSIC researchers use whole living cells as 'templates' to seek for bioactive molecules
A study performed by researchers at the Institute for Advanced Chemistry of Catalonia (IQAC-CSIC) from the Spanish National Research Council (CSIC) pioneers the use of whole living cells (human lung adenocarcinoma) in dynamic combinatorial chemistry systems. This research, published in the journal Angewandte Chemie International Edition, proposes a new methodology to discover new bioactive molecules in a realistic biological medium. This methodology could help in the future to develop methods to differentiate healthy versus cancer cells, or to protect the extracellular matrix against pathogens. (2020-05-27)

Nature unveiling herself before science
21st century societal challenges such as demographic developments and an ageing population demand for new functional materials, such as for bone prostheses. Nature often serves as inspiration when designing these materials. In a recent study published in Analytical Chemistry, a team led by Dennis Kurzbach of the University of Vienna reports an innovative approach for high-resolution real-time monitoring of calcium phosphate mineralisation. They showed how next generation NMR technology allows to create new knowledge about the efficiency of natural materials. (2020-05-19)

New model gives wineries better data from existing tests
WSU scientists present a new model that allows winemakers to get measurements in their wine that previously required difficult, tedious, or expensive testing. (2020-05-18)

Chemistry job seekers face tough outlook during pandemic
Even though it's been over a decade, the 2008 recession and its effects still loom over the chemistry enterprise. And now with the COVID-19 pandemic shutting down labs and universities across the world, chemistry students and professionals are again facing hiring freezes, reduced pay and other career obstacles. Chemical & Engineering News, the weekly newsmagazine of the American Chemical Society, spoke with chemists about how they're navigating the current economic downturn. (2020-05-13)

Dogs can detect traces of gasoline down to one billionth of a teaspoon
Trained dogs can detect fire accelerants such as gasoline in quantities as small as one billionth of a teaspoon, according to new research by University of Alberta chemists. The study provides the lowest estimate of the limit of sensitivity of dogs' noses and has implications for arson investigations. (2020-05-12)

Discovery of bacterial enzyme activity could lead to new sugar-based drugs
Researchers from DTU have revealed the structure of an enzyme that can convert low-cost sugars into hard-to-produce alpha-GalNAc sugars with therapeutic properties for e.g. cancer drugs. (2020-05-04)

Water replaces toxins: Green production of plastics
A new way to synthesize polymers, called hydrothermal synthesis, can be used to produce important high-performance materials in a way which is much better for the environment. Dangerous toxins which usually have to be used to produce theses polymers can be substituted by water. (2020-04-21)

Study finds evidence for existence of elusive 'metabolon'
For more than 40 years, scientists have hypothesized the existence of enzyme clusters, or 'metabolons,' in facilitating various processes within cells. Using a novel imaging technology combined with mass spectrometry, researchers at Penn State, for the first time, have directly observed functional metabolons involved in generating purines, the most abundant cellular metabolites. The findings could lead to the development of novel therapeutic strategies that disrupt the progression of cancer. (2020-04-16)

Pushing the limits of 2D supramolecules
Researchers at the University of South Florida have reached a 'world record' in the development of two-dimensional supramolecules. (2020-04-16)

Texas A&M chemists working on drugs To treat COVID-19
In the wake of the novel coronavirus pandemic, Texas A&M University chemist Wenshe Ray Liu and his research team have focused their lab solely on searching for drugs to treat COVID-19. The Liu group was the first to identify the antiviral drug remdesivir as a viable medicine to treat COVID-19 in a research study published in late January. The drug was originally developed in response to the 2014 Ebola pandemic. (2020-04-06)

Can soap really 'kill' the coronavirus? (video)
Constantly being told to wash your hands? Us too. So we're diving into the chemistry behind why soap is so effective against viruses like the coronavirus that causes COVID-19. (2020-03-23)

Russian scientists propose new approach to measuring atoms
Today, when new drugs are designed with the help of supercomputers, and electronic devices operate on a nanoscale, it is very important for scientists to understand how neighboring molecules behave towards each other. For this purpose, they need to know the sizes of atoms with the highest degree of precision. (2020-03-20)

Access to forbidden rings
Chemists (UNIGE) have now devised a new technique for creating chains of molecular rings that do not use standard chemical interactions but contact with large molecular surfaces that are electron-poor and do not exist in nature. Unlike with standard procedures, this new technique works by autocatalysis - the rarest, but also the most ambitious, type of transformation that exists in chemistry. The results open up new prospects for molecular cyclization. (2020-03-18)

Chemists create new artificial enzyme
Rajeev Prabhakar, a computational chemist at the University of Miami, and his collaborators at the University of Michigan have created a novel, synthetic, three-stranded molecule that functions just like a natural metalloenzyme, or an enzyme that contains metal ions. (2020-03-10)

Solving a mystery in 126 dimensions
One of the fundamental mysteries of chemistry has been solved by Australian scientists - and the result may have implications for future designs of solar cells, organic light-emitting diodes and other next gen technologies. (2020-03-05)

DNA sugars characterised in unprecedented resolution, atom by atom
For the cover of its latest issue the ACS Central Science journal has selected a piece of work conducted by the Spectroscopy Group of the UPV/EHU's Department of Physical Chemistry, and the Biofisika Institute (CSIC - UPV/EHU). In this research the structure of the sugars forming part of DNA have for the first time been isolated and specified with atomic-level resolution. The necessary instruments were developed for this purpose and that was how unprecedented resolution was achieved. (2020-03-04)

'Triangle 2' plastic containers may see environmental makeover
Cornell chemists can demonstrate how to make high-density polyethylene with better control over polymer chain lengths, which allows for improvement over physical properties such as processability and strength, according to research published Dec. 27, 2019, in the Journal of the American Chemical Society. (2020-03-04)

Tying up molecules as easily as you tie up your laces
Since the 1970s, scientists have been trying to knot molecules together to create new, custom-made mechanical properties, which will give rise to new materials. Today, researchers (UNIGE) have developed a simple and effective technique for tying knots in molecules, and have for the first time observed the changes in properties that result from these interlockings. The results open up new perspectives for designing materials and transferring information molecularly. (2020-02-27)

Discovery of entirely new class of RNA caps in bacteria
The group of Dr. Hana Cahová of the Institute of Organic Chemistry and Biochemistry of the CAS, in collaboration with scientists from the Institute of Microbiology of the CAS, has discovered an entirely new class of dinucleoside polyphosphate 5'RNA caps in bacteria and described the function of alarmones and their mechanism of function. The discovery was recently published in the journal Nature Communications. (2020-02-26)

Green approach accelerates process optimization and retrieval of 'switchable' solvents
Researchers have demonstrated a new, green technology for both accelerated screening and retrieving 'switchable' solvents used in green chemistry applications. The new approach makes the screening process hundreds of times faster and drastically accelerates the rate at which solvents can be retrieved from solution. (2020-02-18)

New synthesis methods enhance 3D chemical space for drug discovery
After helping develop a new approach for organic synthesis -- carbon-hydrogen functionalization -- scientists at Emory University are now showing how this approach may apply to drug discovery. Nature Catalysis published their most recent work -- a streamlined process for making a three-dimensional scaffold of keen interest to the pharmaceutical industry. (2020-02-11)

Researchers look to fungus to shed light on cancer
A team of Florida State University researchers from the Department of Chemistry and Biochemistry found that a natural product from the fungus Fusicoccum amygdali stabilizes a family of proteins in the cell that mediate important signaling pathways involved in the pathology of cancer and neurological diseases. (2020-02-11)

CCNY chemists develop safer hydrogenation processes
Safe and environmentally-friendly hydrogen gas on demand could be on the horizon following a new 'hydrogenation' chemical process in development at The City College of New York. Led by Mahesh K. Lakshman, the research uniquely bypasses the need for an external source of hydrogen gas to accomplish a wide range of hydrogenations. It appears as an inside cover feature in the 2020 issue #1 of journal 'Advanced Synthesis and Catalysis.' (2020-02-10)

New details on how a viral protein puts the brakes on virus replication
Researchers used computational chemistry, biochemistry and virology to uncover new information on how viruses such as West Nile, dengue and Zika replicate. (2020-02-07)

Sweet nanoparticles trick kidney
Researchers engineer tiny particles with sugar molecules to prevent side effect in cancer therapy. (2020-02-04)

Principles for a green chemistry future
A team led by researchers from the Yale School of Forestry & Environmental Studies recently authored a paper featured in Science that outlines how green chemistry is essential for a sustainable future. (2020-01-24)

McMaster chemists find new way to break down old tires into material for new ones
A team of chemists at McMaster University has discovered an innovative way to break down and dissolve the rubber used in automobile tires, a process which could lead to new recycling methods that have so far proven to be expensive, difficult and largely inefficient. (2020-01-13)

'Bilingual' molecule connects two basic codes for life
'Much like a translator enables communication between two people from different regions of the world, we envision that our bilingual molecule will enable us to mediate new forms of communications between nucleic acids and proteins in the cellular environment,' says Jennifer Heemstra, associate professor of chemistry at Emory University. (2020-01-09)

IKBFU Scientists study molecular elements effective in countering malaria
The scientists research a building block of organic molecules needed for medical chemistry development. Spirocycles in nature is an element, that chemists are crazy about. This element presents in artemisinin, the most effective group of drugs against malaria. (2019-12-20)

Reflecting on the year in chemistry
A lot can happen in a year, especially when it comes to science. As 2019 draws to a close, Chemical & Engineering News (C&EN), the weekly newsmagazine of the American Chemical Society, is highlighting the year's biggest stories in chemistry, top research trends and important developments in a special issue. In addition, the magazine makes some bold predictions for chemistry in 2020. (2019-12-18)

Scientist breaks down chemistry in iconic cartoons: SpongeBob SquarePants and Popeye
Are bananas actually that slippery? Could spinach give you superhuman strength? And what the heck is Toon Acid? This week, watch some cartoons alongside our writer and host, Sam Jones, and learn whether their chemistry checks out. (2019-12-16)

One-third of recent global methane increase comes from tropical Africa
One-third of recent global methane increase comes from tropical Africa. (2019-12-11)

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