Current Circadian Rhythms News and Events

Current Circadian Rhythms News and Events, Circadian Rhythms News Articles.
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Effective treatment for insomnia delivered in a few short phone calls
In a statewide study of adults over 60 with osteoarthritis, researchers found that effective treatment for insomnia can be delivered in a few short phone calls. (2021-02-22)

How location dictates biological clocks of species: Study in beetles offers new insights
Biological clocks are ubiquitous in living organisms and govern their behavioral pattern, from sleep-wake cycle to reproduction. Although they are well-understood, how they differ based on geographic location is unclear. In a new study, scientists from Japan report variations in the biological clocks of red flour beetles across the country, offering new insights into how they work. (2021-02-18)

Timing of physical activity linked to fitness levels, CV risk for men with type 2 diabetes
Research published in Diabetes Care by Brigham and Women's Hospital and Joslin Diabetes Center investigators, along with collaborators, reports a correlation between the timing of moderate-to-vigorous physical activity and cardiovascular fitness and health risks for individuals who have type 2 diabetes and obesity or overweight. (2021-02-17)

Understanding cellular clock synchronization
In humans, the disruption of circadian clocks is the cause of many metabolic diseases. Thanks to an observation tool based on bioluminescence, a research (UNIGE) were able to demonstrate that cells that compose a particular organ can be in-phase, even in the absence of the central brain clock. Indeed, the scientists managed to restore circadian function in the liver in completely arrhythmic mice, demonstrating that neurons are not unique in their ability to coordinate. (2021-02-17)

Researchers find a novel connection between cell metabolism and cell division
Many biological processes are subject to rhythmic changes. Well-known examples of this are the so-called circadian rhythm, an ''internal clock'' with a period of around 24 hours, or the shorter ultradian rhythm. Cell division is often linked to these rhythms. Biologists from Saarbrücken and Kaiserslautern have now found out that these rhythms and their coupling with cell division is closely related to hydrogen peroxide. The study was published in the renowned journal Nature Chemical Biology. (2021-02-16)

Nightly sleep of five hours, less, may increase risk of dementia, death among older adults
New research from investigators at Brigham and Women's Hospital explores the connection between sleep disturbances and deficiencies among older adults and risk of dementia and death, finding that risk of dementia was double among participants who reported getting less than five hours of sleep compared to those who reported 7-8 hours of sleep per night. (2021-02-11)

Tuning the circadian clock, boosting rhythms may be key to future treatments and medicines
Subconsciously, our bodies keep time for us through an ancient means - the circadian clock. A new University of California, Irvine-led article reviews how the clock controls various aspects of homeostasis, and how organs coordinate their function over the course of a day. (2021-02-11)

Study links exposure to nighttime artificial lights with elevated thyroid cancer risk
People living in regions with high levels of outdoor artificial light at night may face a higher risk of developing thyroid cancer. The finding comes from a study published early online in CANCER, a peer-reviewed journal of the American Cancer Society. (2021-02-08)

As you look around, mental images bounce between right and left brain
A new study in Neuron explains how the brain helps us remember what we've seen, even as it shifts around in our visual system. That ability--to remember that something is the same thing no matter how it's moving around relative to our eyes--is what gives us the freedom to control where we look. (2021-02-08)

Signs of burnout can be detected in sweat
EPFL engineers, working in association with startup Xsensio, have developed a wearable system that can continually measure the concentration of cortisol - the stress hormone - in human sweat. Their device can eventually help doctors better understand and treat stress-related conditions like burnout and obesity. (2021-02-05)

Genes that dance to the circadian rhythm
Scientists at EPFL have made breakthrough discoveries on the circadian clock and how it affects gene expression. Some of the findings suggest a biological underpinning for different behaviors in people, such as morning people, nappers, evening people, night owls etc. (2021-01-29)

Light pollution linked to preterm births, reduced birth weights
Researchers discovered that light pollution is linked to preterm birth, a shortened gestational length, and reduced birth weight. babies born too early have higher rates of death and disability. In 2018, preterm birth and low birth weight accounted for roughly 17% of infant deaths (deaths before one year of age). Researchers hope this spawns policy discussion around minimizing light pollution. (2021-01-28)

Women's menstrual cycles temporarily synchronize with Moon cycles
An analysis of long-term menstrual cycle records kept by 22 women for up to 32 years shows that women with cycles lasting longer than 27 days intermittently synchronized with cycles that affect the intensity of moonlight and the moon's gravitational pull. This synchrony was lost as women aged and when they were exposed to artificial light at night. The (2021-01-27)

Light pollution linked to preterm birth increase
Scientists conducted the first study to examine the fetal health impact of light pollution based on a direct measure of skyglow, an important aspect of light pollution. Using an empirical regularity discovered in physics, called Walker's Law, a team from Lehigh University, Lafayette College and the University of Colorado Denver in the U.S., found evidence of reduced birth weight, shortened gestational length and preterm births. (2021-01-25)

When -- not what -- obese mice ate reduced breast cancer risk
University of California San Diego School of Medicine and Moores Cancer Center researchers report that intermittent fasting reduced breast cancer risk in obese mice. (2021-01-25)

A world first in circadian clock manipulation
A new method developed by Nagoya University and Groningen University scientists allows for reversible manipulation of the circadian clock period using a light-activated switch. Compounds which act on clock proteins were identified through large-scale chemical screening, and modified to include a light-activated switch, which was further modified to react to non-harmful visible light, creating a non-toxic and fully reversible circadian clock control process. (2021-01-24)

Common pesticides stop bees and flies from getting a good night's sleep
Just like us, many insects need a decent night's sleep to function properly, but this might not be possible if they have been exposed to neonicotinoid insecticides, the most common form of insecticide used worldwide, suggests research by academics at the University of Bristol. (2021-01-21)

Deep sleep takes out the trash
By examining fruit flies' brain activity and behavior, the researchers found that deep sleep has an ancient, restorative power to clear waste from the brain. This waste potentially includes toxic proteins that may lead to neurodegenerative disease. (2021-01-20)

An unexpected, and novel, target for prostate cancer - our biological clock
Researchers find that CRY-1, a regulator of circadian rhythms, promotes tumor progression by altering DNA repair. (2021-01-15)

Hospitals must help their own COVID long-haulers recover, experts argue
Thousands of frontline health care workers risked their lives to save others during the pandemic. Some are suffering long-term complications of COVID-19. Yet there are no clear guidelines in most institutions to provide the necessary support to help their workers recover and return to work. Without accommodations, COVID long-haulers may be forced to leave the health care workforce -- at a time when COVID is surging again. (2021-01-12)

Immune system killer cells controlled by circadian rhythms
An exhaustive dataset drawn from mammalian macrophage cells establishes that macrophage activity is controlled by circadian timing, and - with a substantial mismatch between oscillating proteins and mRNA - hints at unexpected calibration of that timing. (2021-01-12)

How the circadian clock regulates liver genes in time and space
EPFL scientists have carried out the first comprehensive study of how genes in the liver perform their metabolic functions in both space and time of day. Monitoring almost 5000 genes at the level of the individual cell across a 24-hour period, the researchers have modelled how the circadian clock and liver functions crosstalk throughout the day in sync with the feeding-fasting cycle. (2021-01-11)

Bacteria can tell the time
New research reveals that bacteria have internal clocks that align with the 24-hour cycle of life on Earth. (2021-01-08)

New USC study on circadian clock shows "junk DNA" plays a key role in regulating rhythms
Researchers have been trying to figure out what regulates molecular circadian clocks, in search of new insights into diseases like Alzheimer's, cancer and diabetes. Until now, that research has focused on what is known as clock genes. But new research reveals the discovery of a new cog in the circadian clock - a genome-wide regulatory layer made up of small chains of non-coding nucleotides known as micro RNAS (miRNAs). (2021-01-04)

Uncovering how plants see blue light
Plants can perceive and react to light across a wide spectrum. New research from the UC Davis College of Biological Sciences shows how plants can respond to blue light in particular by revealing the structure of cryptochrome-2, the molecule that reacts to blue light. (2021-01-04)

Controlling cardiac waves with light to better understand abnormally rapid heart rhythms
Over 300,000 people die each year in the US due to sudden cardiac death. In many cases, sudden cardiac death is caused by abnormally rapid heart rhythms called tachycardias, which means the heart cannot pump adequate blood to the body. In Chaos, researchers use mice to study tachycardias and find there are intrinsic mechanisms that exist in heart tissue that they hypothesize lead to the self-termination of rapid cardiac rhythm. (2020-12-22)

Plants can be larks or night owls just like us
Plants have the same variation in body clocks as that found in humans, according to new research that explores the genes governing circadian rhythms in plants. (2020-12-18)

NBA 'bubble' reveals the ultimate home court advantage, study finds
Using the NBA's travel-less bubble as a natural experiment, a new statistical analysis suggests performance on the road depends on aligning the internal body clock with the new time zone and quality of sleep. (2020-12-11)

Mystery solved with math: cytoplasmic traffic jam disrupts sleep-wake cycles?
KAIST mathematicians and their collaborators at Florida State University have identified the principle of how aging and diseases like dementia and obesity cause sleep disorders. A combination of mathematical modelling and experiments demonstrated that the cytoplasmic congestion caused by aging, dementia, and/or obesity disrupts the circadian rhythms in the human body and leads to irregular sleep-wake cycles. This finding suggests new treatment strategies for addressing unstable sleep-wake cycles. (2020-12-11)

Predicting heart disease from the skin
Jefferson researchers find that the genetic underpinnings of a skin disorder at birth indicate future heart problems. (2020-12-10)

Circadian gene mutation increases self-administration of cocaine in mice
University of Pittsburgh researchers reveal a molecular basis for the deep and fundamental connection between the disruption in circadian rhythms and predisposition to substance abuse. (2020-12-02)

Researchers find how stress and the circadian clock affect sleep
Japanese researchers have found a new neural pathway that links the circadian clock, stress, and wakefulness in mammals. They identified a neuron that becomes excessively active when the mammal is under stress, which could trigger insomnia and other sleep disorders. (2020-11-30)

Doctors confirm the existence of multiple chronotypes
Having conducted a large-scale study, a team of scientists improved the classification of human diurnal activity and suggested using 6 chronotypes instead of just 'early birds' and 'night owls'. Two thousand participants, including the employees of the Institute of Medicine of RUDN University, were tested in the course of the research. (2020-11-26)

Defects in mitochondria may explain many health problems observed during space travel
Using data collected from a number of different resources, a multidisciplinary team is reporting discovery of a common thread that drives this damage: mitochondrial dysfunction. The researchers used a systems approach to look at widespread alterations affecting biological function. The findings are reported November 25 in the journal Cell. (2020-11-25)

Brain waves guide us in spotlighting surprises
A new study by MIT and Boston University neuroscientists finds that the dynamic interplay of different brain wave frequencies, rather than dedicated circuitry, appears to govern the brain's knack for highlighting what's surprising and downplaying what's predictable. (2020-11-24)

Rhythm and bleughs: changes in our stomach's rhythms steer us away from disgusting sights
Does the sight of maggots squirming in rotten food make you look away in disgust? The phrase 'makes my stomach turn' takes on a new meaning today as researchers at the University of Cambridge reveal that changes in the rhythm of our stomachs prompt us to look away from disgusting images. (2020-11-24)

Solitary bees are born with a functional internal clock - unlike honeybees
Individuals of the solitary bee Osmia bicornis show a 24-h behavioral cycle as soon as they emerge, unlike young honeybee workers who need to perform brood care around the clock and only develop a daily cycle later in life. This is reflected in a difference in the rate of brain development: in O. bicornis, but not in honeybees, neurons producing the ''pacemaker'' neuromodulator PDF are already maximally active immediately upon emergence. Sociality seems to have promoted a delay in maturation of the internal clock. (2020-11-16)

Internal clocks drive beta cell regeneration
Our body can repair itself after a damage. This phenomenon describes how cells that are still functional start to proliferate to compensate for the loss. By studying diabetic mice, scientists from the University of Geneva and the University Hospitals of Geneva, observed that this regeneration mechanism was under the influence of circadian rhythms, allowing new perspectives to be envisaged to promote beta cell regeneration. (2020-11-11)

Study dives into genetic risk of Alzheimer's and dementia for diverse Latinx groups
To better understand the association of the APOE gene with cognitive decline in Latinx populations, researchers from Brigham and Women's Hospital and collaborators analyzed metrics of cognitive decline in six diverse Latinx populations: those of Cuban, Central American, Dominican, Mexican, Puerto Rican, and South American backgrounds. They found that the APOE-ε4 genetic variant was associated with risk of cognitive decline in Latinx populations, with the strongest effect among those of Cuban backgrounds. (2020-11-06)

Biological clock and extra gene pairs control important plant functions
New understanding of circadian rhythms could be key to stronger, drought-resistant crops in the face of climate change. (2020-11-05)

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