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Current Circadian Rhythms News and Events, Circadian Rhythms News Articles.
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The rhythm of the Arctic summer
Our internal circadian clock regulates daily life processes and is synchronized by external cues, the so-called Zeitgebers. The main cue is the light-dark cycle, whose strength is largely reduced in extreme habitats such as in the Arctic during the polar summer. Using a radiotelemetry system a team of researchers from the Max Planck Institute for Ornithology have now found, in four bird species in Alaska, different daily activity patterns ranging from strictly rhythmic to completely arrhythmic. (2013-06-19)

Key protein is linked to circadian clocks, helps regulate metabolism
Inside each of us is our own internal timing device. It drives everything from sleep cycles to metabolism, but the inner-workings of this so-called (2013-06-18)

Investigational drug improves sleep disorder among the blind
An investigational new drug significantly improved a common and debilitating circadian rhythm sleep disorder that frequently affects people who are completely blind, a multicenter study finds. The results were presented Monday at The Endocrine Society's Annual Meeting in San Francisco. (2013-06-17)

Scientists map the wiring of the biological clock
In the June 5 issue of Neuron, WUSTL biologist Erik Herzog and his colleagues report the discovery of a crucial part of the biological clock: the wiring that sets its accuracy to within a few minutes out of the 1440 minutes per day. This wiring uses the neurotransmitter, GABA, to connect the individual cells of the biological clock in a fast network that changes strength with time of day. (2013-06-05)

Circadian rhythms control body's response to intestinal infections, UCI-led study finds
Circadian rhythms can boost the body's ability to fight intestinal bacterial infections, UC Irvine researchers have found. (2013-05-31)

Sweet dreams in the North Sea
Night shift workers and daytime workers in the offshore oil industry report similar sleep problems after a two-week work period, according to a Norwegian study. (2013-05-31)

Science news from Harvard Stem Cell Institute
May brought a major advancement in the science of aging when two Harvard Stem Cell Institute researchers announced their discovery of a protein circulating in the blood of mice and humans that shows potential to be a treatment for age-related heart failure. The protein, called GDF-11, reduced the size and thickness of the heart walls when injected into old mice. (2013-05-29)

Death rates decline for advanced heart failure patients, but outcomes are still not ideal
UCLA researchers examining outcomes for advanced heart-failure patients over the past two decades have found that, coinciding with the increased availability and use of new therapies, overall mortality has decreased and sudden cardiac death, caused by the rapid onset of severe abnormal heart rhythms, has declined. However, the team found that even today, with these significant improvements, one-third of patients don't survive more than three years after being diagnosed with advanced disease. (2013-05-23)

Timing of cancer radiation therapy may minimize hair loss, researchers say
Discovering that mouse hair has a circadian clock -- a 24-hour cycle of growth followed by restorative repair -- researchers suspect that hair loss in humans from toxic cancer radiotherapy and chemotherapy might be minimized if these treatments are given late in the day. (2013-05-20)

Gene involved in neurodegeneration keeps clock running
Northwestern University scientists have shown a gene involved in neurodegenerative disease also plays a critical role in the proper function of the circadian clock. In a study of the common fruit fly, the researchers found the gene, called Ataxin-2, keeps the clock responsible for sleeping and waking on a 24-hour rhythm. Without the gene, the rhythm of the fruit fly's sleep-wake cycle is disturbed, making waking up on a regular schedule difficult for the fly. (2013-05-16)

Out of sync with the world: Body clocks of depressed people are altered at cell level
Every cell in our bodies runs on a 24-hour clock, tuned to the night-day, light-dark cycles that have ruled us since the dawn of humanity. But new research shows that the clock may be broken in the brains of people with depression -- even at the level of the gene activity inside their brain cells. (2013-05-13)

Circadian clock gene rhythms in brain altered in depression, UC Irvine Health study finds
UC Irvine Health researchers have helped discover that genes controlling circadian clock rhythms are profoundly altered in the brains of people with severe depression. These clock genes regulate 24-hour circadian rhythms affecting hormonal, body temperature, sleep and behavioral patterns. (2013-05-13)

Rats take high-speed multisensory snapshots
New research from the laboratory of CSHL neuroscientist Adam Kepecs shows that rats create high-speed (2013-05-07)

FDA warning against high dose antidepressant prescription may be unwarranted, study finds
A new Ann Arbor VA Healthcare System and University of Michigan study calls into question the FDA's warning against high dosages of citalopram after finding no increased risk for abnormal heart rhythms or death in patients who took daily doses of more than 40 milligrams before or after the warning took effect. (2013-05-03)

1 bad gene: Mutation that causes rare sleep disorder linked to migraines
A gene mutation associated with a rare sleep disorder surprisingly also contributes to debilitating migraines. A new discovery could change the treatment of migraines by allowing the development of drugs specifically designed to treat the chronic headaches. (2013-05-01)

Study explains what triggers those late-night snack cravings
A study co-authored by an Oregon Health and Science University researcher finds that the circadian system increases hunger and cravings for sweet, starchy and salty foods in the evenings. Eating higher-calorie foods in the evening can be counterproductive if weight loss is a goal since the human body handles nutrients differently depending on the time of day. (2013-04-29)

Rats' and bats' brains work differently on the move
A new study of brain rhythms in bats and rats challenges a widely-used model -- based on rodent studies -- of how animals navigate their environment. To get a clearer picture of processes in the mammal brain during spatial navigation, neuroscientists must study more species, say the two University of Maryland College Park scientists involved in the study. (2013-04-18)

Healing by the clock
Genetic screening in flies reveals that the circadian clock regulates intestinal regeneration in response to damage, meaning that gut healing fluctuates according to the time of day. (2013-04-11)

Sound stimulation during sleep can enhance memory
Slow oscillations in brain activity, which occur during so-called slow-wave sleep, are critical for retaining memories. Researchers reporting online Apr. 11 in the Cell Press journal Neuron have found that playing sounds synchronized to the rhythm of the slow brain oscillations of people who are sleeping enhances these oscillations and boosts their memory. (2013-04-11)

Cancers don't sleep: The Myc oncogene can disrupt circadian rhythm
The Myc oncogene can disrupt the 24-hour internal rhythm in cancer cells. Disrupting circadian rhythm may benefit cancer cells by unleashing their metabolism from the constraints of the molecular clock. (2013-04-09)

2013 Wiley Prize awarded for circadian rhythm research
Deborah E. Wiley, Chair of the Wiley Foundation, John Wiley & Sons Inc., today awarded the 2013 Wiley Prize in Biomedical Sciences to Dr. Michael Young, Rockefeller University, Dr. Jeffrey Hall, Brandeis University (Emeritus), and Dr. Michael Rosbash, Brandeis University. (2013-04-08)

Symbiotic bacteria program daily rhythms in squid using light and chemicals
Glowing bacteria inside squid use light and chemical signals to control circadian-like rhythms in the animals, according to a study to be published on Apr. 2 in mBio®, the online open-access journal of the American Society for Microbiology. The results of the study show that, in addition to acting as a built-in lamp, the bacteria also control when the squid expresses a gene that entrains, or synchronizes, circadian rhythms in animals. (2013-04-02)

Study links diabetes risk to melatonin levels
New research from Brigham and Women's Hospital finds that the amount of melatonin a person secretes during sleep may predict their risk of developing type 2 diabetes. The study appears in the April 3, 2013 issue of JAMA. (2013-04-02)

Our internal clocks can become ticking time bombs for diabetes and obesity
If you're pulling and all-nighter to finish a term paper, a new parent up all night with a fussy baby, or simply can't sleep like you once could, then you may be snoozing on good health. (2013-04-01)

2013 Wiley Prize to be awarded at Apr. 5 event
Deborah E. Wiley, Chair of The Wiley Foundation, John Wiley & Sons, Inc. will present the 2013 Wiley Prize in Biomedical Sciences to Dr. Michael Young, Rockefeller University, Dr. Jeffrey Hall, Brandeis University (Emeritus), and Dr. Michael Rosbash, Brandeis University on Friday, Apr. 5. (2013-03-29)

UMMS scientists tie dietary influences to changes in gene expression and physiology
Sometimes you just can't resist a tiny piece of chocolate cake. Even the most health-conscious eaters find themselves indulging in junk foods from time to time. New research by scientists at the University of Massachusetts Medical School raises the striking possibility that even small amounts of these occasional indulgences may produce significant changes in gene expression that could negatively impact physiology and health. (2013-03-28)

Putting the clock in 'cock-a-doodle-doo'
Of course, roosters crow with the dawn. But are they simply reacting to the environment, or do they really know what time of day it is? Researchers reporting on March 18 in Current Biology, a Cell Press publication, have evidence that puts the clock in (2013-03-18)

Night shifts may be linked to increased ovarian cancer risk
Working night shifts might increase the risk of developing ovarian cancer, indicates research published in Occupational and Environmental Medicine. (2013-03-14)

Rutgers neuroscientist sheds light on cause for 'chemo brain'
It's not unusual for cancer patients being treated with chemotherapy to complain about not being able to think clearly, connect thoughts or concentrate on daily tasks. The complaint -- often referred to as chemo-brain -- is common. The scientific cause, however, has been difficult to pinpoint. New research by Rutgers University behavioral neuroscientist Tracey Shors offers clues for this fog-like condition, medically known as chemotherapy-induced cognitive impairment. (2013-02-21)

Circadian clock linked to obesity, diabetes and heart attacks
Disruption in the body's circadian rhythm can lead not only to obesity, but can also increase the risk of diabetes and heart disease. That is the conclusion of the first study to show definitively that insulin activity is controlled by the body's circadian biological clock. (2013-02-21)

Why living against the clock is a risky business
Living against the clock -- working late-night shifts or eating at inappropriate times, for example -- can come with real health risks, metabolic syndrome, obesity, and diabetes among them. Now, researchers reporting in Current Biology, a Cell Press publication, on Feb. 21 have new evidence to explain why it matters not just what mice (or by extension, people) eat, but also when they eat it. (2013-02-21)

When it comes to genetic code, researchers prove optimum isn't always best
Imagine two steel springs identical in look and composition but that perform differently because each was tempered at a different rate. A team of researchers including a Texas A&M University molecular biologist has shown that concept -- that the speed of creation affects performance -- applies to how a protein they studied impacts an organism's circadian clock function. (2013-02-18)

'Snooze button' on biological clocks improves cell adaptability
The circadian clocks that control and influence dozens of basic biological processes have an unexpected 'snooze button' that helps cells adapt to changes in their environment. (2013-02-17)

A neural basis for benefits of meditation
Mindfulness meditation training in awareness of present moment experience, such as body and breath sensations, prevents depression and reduces distress in chronic pain. In a new paper, Brown University scientists propose a neurophysiological framework to explain these clinical benefits. (2013-02-13)

FASEB SRC announces conference registration open for: Melatonin Biology: Actions & Therapeutics
The Federation of American Societies for Experimental Biology (FASEB) announces the opening of registration for the Science Research Conference (SRC): Melatonin Biology: Actions & Therapeutics. (2013-02-11)

Sensing the light, but not to see
In a primitive marine organism, MBL scientists find photosensitive cells that may be ancestral to the (2013-02-06)

Mini stroke symptoms quickly fade, but patients remain at risk
Each year, as many as 500,000 Americans experience mini strokes called transient ischemic attacks (TIAs). Symptoms quickly go away, usually within an hour, and many people don't seek treatment. But 10 to 15 percent of people who experience TIAs will experience full-blown strokes within three months, and 40 percent of these strokes will occur in the first 24 hours. (2013-02-04)

Identifying all factors modulating gene expression is actually possible!
It was in trying to answer a question related to the functioning of our biological clock that a team lead by Ueli Schibler, a professor at the University of Geneva, Switzerland, has developed a method whose applications are proving to be countless. The researchers wanted to understand how 'timed' signals, present in the blood and controlled by our central clock, located in the brain, act on peripheral organs. (2013-01-31)

12th annual Wiley Prize in Biomedical Sciences awarded
Deborah E. Wiley, Chair of The Wiley Foundation, John Wiley & Sons, Inc., announced today that the twelfth annual Wiley Prize in Biomedical Sciences will be awarded to Dr. Michael Young, Rockefeller University, Dr. Jeffrey Hall, Brandeis University (Emeritus), and Dr. Michael Rosbash, Brandeis University. (2013-01-31)

Wiley Prize in Biomedical Sciences awarded to Rosbash, Hall and Young
The 12th annual Wiley Prize in Biomedical Sciences has been awarded to Brandeis professors Michael Rosbash and Jeffrey Hall and their colleague Michael Young of Rockefeller University for the discovery of the molecular mechanisms governing circadian rhythms. (2013-01-31)

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