Current Clinical Indication News and Events

Current Clinical Indication News and Events, Clinical Indication News Articles.
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Cannabis reduces blood pressure in older adults, according to Ben-Gurion University researchers
''Older adults are the fastest growing group of medical cannabis users, yet evidence on cardiovascular safety for this population is scarce,'' says Dr. Ran Abuhasira of the BGU Faculty of Health Sciences, one of Israel's leading medical faculties, and the BGU-Soroka Cannabis Clinical Research Institute. ''This study is part of our ongoing effort to provide clinical research on the actual physiological effects of cannabis over time.'' (2021-02-08)

Novel effector biology research provides insights into devastating citrus greening disease
Ma and her colleagues at the University of California and the University of Florida used molecular plant pathology approaches to dissect the mechanisms of the ongoing tug-of-war between the citrus host and the bacterial pathogen that causes citrus greening disease. (2021-01-21)

Strategy tested in mice protects against SARS-CoV-2 & coronaviruses that represent human threats
An immunization strategy tested in mice protects against infection from SARS-CoV-2, as well as from potentially emerging animal coronaviruses, researchers say. (2021-01-12)

Ibrutinib with rituximab in previously untreated CLL: indication of added benefit over FCR
Ibrutinib with rituximab in previously untreated CLL: indication of added benefit over FCR. The new drug combination prolongs overall survival in patients in good general health. No study data are available for other patient groups. (2021-01-05)

Researchers deconstruct ancient Jewish parchment using multiple imaging techniques
Scientists in Romania used multiple, complementary imaging techniques to non-invasively study the composition of an aged Jewish parchment scroll. The various analyses can determine the types of materials used in the manuscript's manufacturing, providing historical context for objects of mysterious provenance. The research also offers insights into the item's degradation over time, including indications of previous repair attempts. All of this information helps conservators determine how best to restore such antiques to their original condition. (2020-12-18)

Researchers determine factors associated with ovary removal in patients with ovarian torsion
To determine the factors associated with an increased likelihood for ovary removal during the time of surgery for ovarian torsion, researchers from Boston University School of Medicine (BUSM), conducted a retrospective study of patients from a racially diverse, urban safety-net hospital with a diagnosis of ovarian torsion during a four-and-a-half-year period. (2020-12-18)

What do slight arm movements reveal about our breathing and health?
Special activity trackers can be used to fairly accurately determine the respiratory rate of people while they sleep. This is the result of a new study conducted by researchers at Martin Luther University Halle-Wittenberg (MLU) together with Charité - Universitätsmedizin Berlin and published in the journal Scientific Reports. In the future, activity trackers could be used to detect the early stages of a disease, as a person's respiratory rate can indicate signs of an undetected medical problem. (2020-11-23)

Gambling addiction: an aid from patients' stories
How do people affected by pathological gambling tell their story? What information can we extract from their narratives? For the first time, a study conducted by SISSA and University of Roma Tre has analysed in detail the words and linguistic constructions used by people suffering from gambling. The researchers identified several characteristic elements of their emotional and cognitive state. The study, published in Addictive disorders and their treatment, opens up new scenarios for the development of recovery and prevention paths based on linguistic skills. (2020-11-10)

Early indications of thrombosis help in preventing postoperative complications
It is well-known that surgeries can be complicated by life-threatening thromboses that are hard to predict and not easy to prevent. The authors managed to find a new prognostic laboratory sign of the imminent postoperative thrombosis; remarkably, this sign appears on the first postoperative day, a few days before deep vein thrombosis of the lower limbs develops. (2020-10-27)

Scientists discover bacterium linked to deadly childhood disorder
Scientists at the Center for Infection and Immunity (CII) at Columbia University Mailman School of Public Health have discovered bacteria linked to post-infectious hydrocephalus (PIH), the most common cause of pediatric hydrocephalus worldwide. Results of the study led by Pennsylvania State University with CII scientists and clinical colleagues in Uganda are published in the journal Science Translational Medicine. (2020-09-30)

COVID-19: Saliva tests could detect silent carriers
Testing self-collected saliva samples could offer an easy and effective mass testing approach for detecting asymptomatic COVID-19. (2020-09-27)

Educational mailing fails to improve medication use in patients with atrial fibrillation
Prevention drugs, according to results of the IMPACT-AFib trial presented in a Hot Line session today at ESC Congress 2020. Patients with atrial fibrillation are at increased risk of stroke. Studies have shown that most of these strokes can be prevented with oral anticoagulation. However, oral anticoagulant medication is underused by patients with atrial fibrillation. (2020-09-01)

Castration-resistant prostate cancer at high risk of metastasis: enzalutamide has added benefit
Castration-resistant prostate cancer at high risk of metastasis: enzalutamide has added benefit. For the first time, new data from the PROSPER study show an advantage in overall survival that outweighs the disadvantages in some side effects. (2020-08-19)

Does city life make bumblebees larger?
Does urbanisation drive bumblebee evolution? A new study by Martin Luther University Halle-Wittenberg (MLU) and the German Centre for Integrative Biodiversity Research (iDiv) Halle-Jena-Leipzig provides an initial indication of this. According to the study, bumblebees are larger in cities and, therefore, more productive than their rural counterparts. In 'Evolutionary Applications', the research team reports that differences in body size maybe caused by the increasingly fragmented habitats in cities. (2020-08-17)

Large study confirms vitamin D does not reduce risk of depression in adults
In a study of 18,000+ participants, the risk of depression was not significantly different between those receiving vitamin D and those on placebo. (2020-08-04)

Darolutamide in prostate cancer: Indication of considerable added benefit
The advantages in the outcome categories of mortality, morbidity and health-related quality of life are not accompanied by disadvantages. (2020-08-03)

Primary care physicians during the COVID-19 epidemic
Scientists from the University of Geneva has analysed clinical data from more than 1,500 ambulatory patients tested for COVID-19. Their results point out the great disparity in symptoms between inpatient and outpatient care and the diagnostic difficulties that can result. They highlight the need for greater involvement of primary care physicians in defining and implementing health policies aimed at controlling such an epidemic, as well as the need to strengthen academic research in primary care. (2020-07-22)

Care for cats? So did people along the Silk Road more than 1,000 years ago
Common domestic cats, as we know them today, might have accompanied Kazakh pastoralists as pets more than 1,000 years ago. This is indicated by new analyses done on an almost complete cat skeleton found during an excavation along the former Silk Road in southern Kazakhstan. An international research team has reconstructed the cat's life, revealing astonishing insights into the relationship between humans and pets at the time. The study will appear in 'Scientific Reports'. (2020-07-09)

Using Epo against Covid-19
The doping agent erythropoietin could attenuate severe progression of COVID-19. (2020-07-06)

Romosozumab in osteoporosis: Considerable added benefit for women after menopause
Treatment leads to fewer vertebral fractures and to fewer other typical fractures in postmenopausal women with severe osteoporosis at high risk of fracture. (2020-06-15)

Study shows opioid, sedative and antidepressant use pre-surgery leads to worse outcomes
A study led by University of Kentucky Markey Cancer Center researchers showed that patients who already used opioids, sedatives or antidepressants prior to colorectal surgery experience significantly more complications post-surgery. (2020-06-08)

T cell immunity in the elderly
A study by Monash Biomedicine Discovery Institute (BDI) expands the understanding of the molecular pathways that control T cell function and survival and how it relates to declining T cell immunity in the elderly. (2020-06-05)

Ribociclib in breast cancer: Added benefit for certain women after menopause
After expiry of the G-BA decisions, IQWiG reassessed the drug in two combinations. The new data cut-offs used for this purpose confirm both advantages and disadvantages. (2020-06-05)

Obstructive sleep apnoea: Mandibular advancement device helps against daytime sleepiness
Obstructive sleep apnoea: mandibular advancement device helps against daytime sleepiness In obstructive sleep apnoea, wearing a plastic splint in the mouth at night to keep the airways open mechanically is about as effective as positive airway pressure therapy with a sleep mask. (2020-06-03)

Loss of smell, taste changes associated with COVID-19: Canadian study
Loss of smell (anosmia) and changes in taste (dysgeusia) were strongly associated with SARS-CoV-2, according to a Canadian study published in CMAJ (Canadian Medical Association Journal) https://www.cmaj.ca/content/early/2020/05/27/cmaj.200869. (2020-05-27)

Physio support in COVID-19 recovery
New physiotherapy guidelines are targeting COVID-19 patient recovery for respiratory management, exercise and mobilisation in acute hospital wards and Intensive Care Units. The new guidelines published in Australian Journal of Physiotherapy aim to prevent complications of the respiratory system and muscle deconditioning, speed up recovery from mechanical ventilation, and improve long-term physical function and recovery. (2020-04-29)

Soil carbon and nitrogen mineralization after the initial flush of CO2
Healthy soil should have abundant nitrogen to supply plant growth needs, but it should not all be in the inorganic fraction. Rather, organic nitrogen is the preferred storage warehouse from which soil microorganisms can decompose and release inorganic nitrogen to soil and then to plants. This system avoids leaching and volatile losses of nitrogen. Historically, scientists have had difficulty predicting how much nitrogen is made available to plants by soil biological activity due to time and resource constraints. (2020-04-16)

Belle II yields first results in search of the Z' boson
The Belle II experiment started about one year ago. Physical Review Letters has now published the initial results of the detector. The work deals with a new particle in the context of dark matter, which accounts for about 25 percent of the universe. (2020-04-08)

Leaving its mark: How frailty impacts the blood
Fifteen blood metabolites are key for diagnosing the age-related disorder, frailty, new study finds. (2020-04-06)

Lung cancer surgery: Better survival probabilities with a higher case volume
In the surgical treatment of lung carcinoma, the more frequent performance of such interventions has a positive effect on treatment results -- the survival probabilities increase. (2020-04-02)

Study finds music therapy helps stroke patients
New research has found that music therapy sessions have a positive effect on the neurorehabilitation of acute stroke patients, as well as their mood. (2020-03-05)

Eating disorders linked to exercise addiction
New research shows that exercise addiction is nearly four times more common amongst people with an eating disorder. (2020-01-28)

Research shows nasal spray antidote is easiest to give for opioid overdose
Of three possible ways for people to deliver the life-saving antidote naloxone to a person experiencing an opioid overdose, the use of a nasal spray was the quickest and easiest according to research conducted by William Eggleston, clinical assistant professor at Binghamton University, State University of New York, and colleagues at SUNY Upstate Medical University. (2020-01-10)

Outpatient antibiotic prescriptions written without documented reason 18% of the time
A study of outpatient visits to health care providers in the United States during a one-year period suggests 18 percent of antibiotic prescriptions were written without a documented reason for doing so. (2019-12-12)

Up to two-fifths of antibiotic prescriptions in the US could be inappropriate
As much as two fifths (43%) of antibiotic prescriptions in the United States could be inappropriate, warn researchers in a study published by The BMJ today. (2019-12-11)

Concerns over regulation of oral powders or gels sold as medical devices in Europe
Oral powders or gels, sold as medical devices in the European Union (EU), aren't regulated to the same safety standards as those applied to medicines, reveals research published online in the Archives of Disease in Childhood. (2019-12-03)

A quarter of cancer patients experience avoidable delay to diagnosis
One in four cancer patients experienced a delay to their diagnosis that could have been avoided, according to a new study by Cancer Research UK. (2019-12-03)

Clearing damaged cells out of the body helps heal diabetics' blood vessels
Research published today in Experimental Physiology shows that ramping up one of the body's waste disposal system, called autophagy, helps heal the blood vessels of diabetics. (2019-11-17)

Volcanoes under pressure
When will the next eruption take place? Examination of samples from Indonesia's Mount Merapi show that the explosivity of stratovolcanoes rises when mineral-rich gases seal the pores and microcracks in the uppermost layers of stone. These findings result in new possibilities for the prediction of an eruption. (2019-11-15)

Blood test for deadly eye melanoma
A simple blood test could soon become the latest monitoring tool for the early detection of melanoma in the eye. (2019-11-14)

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