Current Codeine News and Events

Current Codeine News and Events, Codeine News Articles.
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After CDC guidance, little change in opioid prescriptions to those at risk of misuse
Research from Saint Louis University finds that among patients at risk for opioid misuse, the odds of receiving a Schedule II opioid (those with high abuse potential) for non-cancer pain were similar to those not at risk, despite new prescribing guidelines from the Centers for Disease Control (CDC). (2020-12-02)

Opioid prescriptions are rising in the U.K, with 14% of patients becoming long-term users
In the U.K., new prescriptions for multiple opioids have risen steadily in recent years, leading to concerning rates of long-term use, especially in older, socially deprived patients. Dr Meghna Jani at the University of Manchester and colleagues report these findings in a new study published October 15 in PLOS Medicine. (2020-10-15)

Researchers develop a yeast-based platform to boost production of rare natural molecules
Researchers at Concordia University in Montreal and in Berkeley, California outline a method to synthesize complex bioactive molecules much more quickly and efficiently. Using cutting-edge synthetic biology approaches, They were able to produce a large amount of benzylisoquinoline alkaloid (BIA) to synthesize an array of natural and new-to-nature chemical structures in a yeast-based platform. This can provide a blueprint for the large-scale production of thousands of products, including the opioid analgesics morphine and codeine. (2020-08-27)

Youth's risks from first-time opioid prescriptions may not be as high as once thought
Young adults and adolescents who are prescribed opioids for the first time may be at a slightly greater risk of developing a substance-related problem later in life, according to a new study co-authored by Indiana University researchers. However, the risk may not be as high as previously thought. (2020-08-10)

New guidelines say breastfeeding is safe after anaesthesia
New guidelines published by the Association of Anaesthetists in the journal Anaesthesia, to coincide with the start of World Breast Feeding Week (1-7 August) say that breastfeeding is safe after the mother has had anaesthesia, as soon as she is alert and able to feed. (2020-07-31)

Heating poppy seeds, but not baking them in muffins, reduces opiate levels
You might have heard the advice to avoid eating a poppy seed bagel or muffin before a drug screen, lest you test positive for opiates. This urban legend is rooted in truth because the tiny black seeds contain small amounts of morphine and codeine that can show up in a drug test. Now, researchers reporting in ACS' Journal of Agricultural and Food Chemistry have studied how different treatments affect levels of opiates in poppy seeds. (2020-05-20)

Opioids for chronic non-cancer pain doubled in quarter century
A review of 24 years of global research has shown opioid prescribing doubled between 1991-2015, with demand most common for chronic conditions such as chronic lower back pain, finds University of Sydney-led research. (2020-02-25)

Does tramadol increase hip fracture risk?
An analysis published in the Journal of Bone and Mineral Research reveals that use of the pain medication tramadol was linked with a higher risk of hip fractures compared with the use of other pain medications in an analysis of a patient database from the United Kingdom. (2020-02-05)

More than half of US opioid prescriptions for dental procedures exceeded 3-day supply recommendations from CDC 2016 guidelines
Dentists are among top prescribers of opioids in the US, however, whether their opioid prescribing exceeds guidance had not been investigated. A new study in the American Journal of Preventive Medicine indicates that more than half of opioid prescriptions issued by dentists exceed the three-day supply recommended by the CDC for acute dental pain management. The findings also show that 29% of dental patients received more powerful opioids than needed for expected post-procedure pain. (2020-02-04)

Researchers say 30% of patients taking opioids experience adverse drug interactions
A new article outlines common drug-drug interactions that alter how the body metabolizes certain opioids, causing decreased efficacy that ultimately can lead to misuse and overdose. The authors estimate that around 30 percent of patients experience such interactions; however, very few are detected and reported. (2019-12-10)

Chronic opioid treatment may raise risk of post-traumatic stress disorder, study finds
While opioids are often prescribed to treat people with trauma-related pain, a new UCLA-led study suggests doctors should use caution before prescribing the drug to those they believe may experience severe stress in the future, in order to reduce the risk the patient will develop PTSD. (2019-12-03)

Estuarine waters hold promise in global pain-relief hunt
The worldwide search for an opioid alternative has made a leap forward -- with a scientific discovery in an Australian fungus indicating effective pain relief and the potential for a safer less addictive drug, helping address the opioid epidemic of deaths by overdose. (2019-10-14)

Codeine misuse in Australia reduced by prescription-only changes
The move to prescription-only codeine in Australia has seen a 50 percent reduction in the monthly rate of codeine-related poisoning calls and halved codeine sales, finds new research led by the University of Sydney. (2019-10-02)

Patients in the US and Canada are likely to receive opioids after surgery
Patients in the United States and Canada are seven times as likely as those in Sweden to receive a prescription for opioid medications after surgery, according to a new multi-institutional study led by researchers from Penn Medicine. Though the United States and Canada had similar prescription rates, patients in the U.S. were prescribed a much higher dosage - as measured by the total morphine milligram equivalents (MME). The findings were published today in JAMA Network Open. (2019-09-04)

Doctors more likely to recommend antihistamines rather than cough & cold medicine for kids
For respiratory infections in children under 12, physicians are increasingly more likely to recommend antihistamines and less likely to recommend cough and cold medicines, a Rutgers study found. Antihistamines are widely used over-the-counter to treat various allergic conditions. However, these medicines have little known benefit for children with colds, and some older antihistamines cause sedation and occasionally agitation in children. (2019-07-29)

High rates of opioid prescriptions for osteoarthritis
Opioids work against severe pain but the risks of side effects and addiction are high. In the US alone, 26 people die every day from overdoses. Now researchers in an international collaboration have investigated how common opioid prescriptions are for osteoarthritis patients in Sweden. It emerged that every fourth patient was prescribed opioids at some point between November 2014 and October 2015. (2019-07-08)

Opioid analgesics increase the risk of pneumonia among persons with Alzheimer's disease
Opioid analgesics were associated with a 30% increase in the risk of pneumonia in persons with Alzheimer's disease, a recent study from the University of Eastern Finland shows. The risk was most pronounced in the first two months of use. This is the first study to investigate the association between opioids and pneumonia in this population. The results were published in the Journal of Alzheimer's Disease. (2019-06-04)

US dentists out-prescribe UK dentists when it comes to opioids
Researchers from the University of Illinois at Chicago have found that dentists practicing in the US write 37 times more opioid prescriptions than dentists practicing in England. And, the type of opioids they prescribe has a higher potential for abuse. (2019-05-24)

New study aims to understand opioid fill patterns in children
Improved understanding of current opioid prescription trends in children is needed to inform development of future pediatric pain management guidelines. (2019-04-27)

Study suggests painkillers taken during pregnancy not a cause of asthma in kids
A study of almost 500,000 women indicates that taking paracetamol or other painkillers during pregnancy is not responsible for increasing the risk of asthma in children. The research, which uses prescription data on painkillers, does support earlier findings that women taking paracetamol during pregnancy are more likely to have children who develop asthma. However, it also suggests that the painkillers are not the cause of this increase. (2019-03-17)

Tonsillectomy in children: Update to guidelines for treating and managing care
The American Academy of Otolaryngology-Head and Neck Surgery Foundation published the Clinical Practice Guideline: Tonsillectomy in Children (Update) today in Otolaryngology-Head and Neck Surgery. The update to the 2011 publication, which includes a large amount of new information that applies to a child considered for tonsillectomy, emphasizes education, counseling, and pain management with several tables and handouts that are user-friendly and helpful to caregivers. (2019-02-05)

Fears over life-saving drug unfounded, finds review
Fears over a drug that can be used to treat alcohol addiction are unfounded, according to its first ever systematic review, led by academics at The University of Manchester. (2019-01-14)

Prescribed opioids raise risk of pneumonia in patients with and without HIV
Taking prescribed opioids raises the risk of pneumonia in individuals with and without HIV, a new Yale-led study finds. (2019-01-07)

Strong painkillers increase the risk of hip fracture among persons with Alzheimer's disease
People using strong painkillers, opioids, have twice the risk of hip fracture compared to non-opioid users, a new study from the University of Eastern Finland shows. The risk was highest in the first two months of opioid use. The results were published in the PAIN journal. (2018-11-26)

New Zealand children's medicine prescriptions examined for first time
A study into the pharmaceutical use of 1.4 million New Zealand children has revealed some significant increases in the use of certain prescription medicines, as well as the positive impact of practitioner education. (2018-09-25)

How the poppy evolved its pain-relieving properties
The unveiling of the poppy genome reveals how a collection of genes fused to endow the plant with its pain-relieving compounds; the plant underwent a notable genome duplication event about 7.8 million years ago, the study's authors say. (2018-08-30)

Scientists decode opium poppy genome
Scientists have determined the DNA code of the opium poppy genome, uncovering key steps in how the plant evolved to produce the pharmaceutical compounds used to make vital medicines. The discovery may pave the way for scientists to improve yields and the disease resistance of the medicinal plant, securing a reliable and cheap supply of the most effective drugs for pain relief and palliative care. (2018-08-30)

Synthesis of opium alkaloids using electric current
Researchers at Johannes Gutenberg University Mainz in Germany have mastered a nearly 50-year-old challenge of electrosynthetic chemistry, namely the electrochemical synthesis of thebaine. (2018-06-28)

Study with implications for opioid crisis finds opioids raise risk of fracture nonunion
Dr. Robert Zura, Professor and Chair of Orthopaedic Surgery at LSU Health New Orleans School of Medicine, was part of a research team reporting that not only may opioid use increase the risk of bone fractures, but opioids may also impair healing. The authors also question their effectiveness in controlling pain. (2018-06-15)

Research supports restrictions on opioid-containing cold medicines for children
Prescription cough and cold medicines containing the opioid hydrocodone were more likely to cause serious side effects in children than those containing codeine, according to a new study from Penn State College of Medicine. The research supports recent U.S. Food and Drug Administration (FDA) restrictions on prescription hydrocodone- and codeine-containing cough medicines for children and suggests that opioids in general should not be prescribed for coughs and colds in pediatric populations. (2018-05-22)

Opioid use prevalent among electronic dance music partygoers
One in 10 electronic dance music (EDM) party attendees have misused opioids in the past year, exceeding the national average, finds a study by the Center for Drug Use and HIV/HCV Research (CDUHR) at NYU Meyers College of Nursing. (2018-03-29)

New vaccine technology shows promise as a tool to combat the opioid crisis
An experimental heroin vaccine induced antibodies that prevented the drug from crossing the blood-brain barrier in mice and rats. (2017-12-18)

Black box warning slows, but doesn't stop, codeine for kids after tonsil removal
Despite an FDA black box warning against prescribing children codeine following tonsil and adenoid removal, 1 in 20 children undergoing these surgeries continued to receive the opioid, a new study suggests. (2017-11-16)

Study shows codeine prescribed to children despite FDA warning against it
A new study shows as many as one in 20 children were still receiving codeine to treat pain after tonsil and adenoid surgery, two years after federal regulators warned doctors that prescribing the opioid to kids after the routine surgeries could be fatal. (2017-11-16)

No significant difference in pain relief for opioids vs. non-opioid analgesics for treating arm or leg pain
For adults coming to the emergency department for arm or leg pain due to sprain, strain, or fracture, there was no difference in pain reduction after two hours with ibuprofen-acetaminophen vs three comparison opioid-acetaminophen (paracetamol) combinations. (2017-11-07)

Many prescription drug users not aware of driving-related risks
A large portion of patients taking prescription drugs that could affect driving may not be aware they could potentially be driving impaired, according to research in the November issue of the Journal of Studies on Alcohol and Drugs. (2017-11-01)

Machine learning detects marketing and sale of Opioids on Twitter
Using advanced machine learning, a cross disciplinary team of University of California San Diego researchers developed technology that mined Twitter to identify entities illegally selling prescription opioids online. (2017-10-25)

Home-brewed poppy seed tea can be lethal, study finds
A home-brewing technique used to extract morphine from unwashed poppy seeds can produce lethal doses of the drug, according to research at Sam Houston State University. (2017-10-10)

Home-Brewed Poppy Seed Tea Can Be Lethal, Study Finds
A home-brewing technique used to extract morphine from unwashed poppy seeds can produce lethal doses of the drug, according to research at Sam Houston State University. (2017-10-10)

Self-medication misuse is high in the Middle East
A new review indicates that there is a massive problem of self-medication misuse in the Middle East. (2017-06-19)

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