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Current Cognitive Function News and Events, Cognitive Function News Articles.
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Dementia can be caused by hypertension
A new study in Cardiovascular Research indicates that patients with high blood pressure are at a higher risk of developing dementia. This research also shows (for the first time) that an MRI can be used to detect very early signatures of neurological damage in people with high blood pressure, before any symptoms of dementia occur. (2018-06-13)

Reversible changes to neural proteins may explain sleep need
Sleep need accumulates over long periods awake, and sleep refreshes the brain. Little is known, however, of the molecular mechanisms underpinning sleep need. Using two mouse models of increased sleep need, researchers found the phosphorylation of an identifiable set of mostly synaptic proteins (SNIPPs) increases while awake and dissipates with sleep. This provides evidence that the phosphorylation/dephosphorylation cycle of SNIPPs may be one major way the brain regulates sleep-wake homeostasis. (2018-06-13)

Better physical fitness and lower aortic stiffness key to slower brain aging
The rate of decline in certain aspects of memory may be explained by a combination of overall physical fitness and the stiffness of the central arteries, researchers from Swinburne's Centre for Human Psychopharmacology have found. (2018-06-12)

Smoking and diabetes linked to brain calcifications
People who smoke or have diabetes may be at increased risk of calcifications in a region of the brain crucial to memory, according to a new study. (2018-06-12)

Children with kidney disease show blood flow changes in brain
Blood flow changes in the brains of children, adolescents and young adults with chronic kidney disease may explain why many face a higher risk of cognitive impairment, according to a new study. (2018-06-12)

A call to neuroscientists to help reveal root causes of chemobrain
Though well documented, cancer-related cognitive impairment (CRCI), known colloquially as chemobrain or chemofog, remains a mystery regarding its underlying neurological causes. In a Forum paper published June 12 in the journal Trends in Neurosciences, researchers at the National Cancer Institute propose a new approach to studying CRCI and call for changes in the way it's diagnosed. (2018-06-12)

Alzheimer's disease: How amyloid aggregates alter neuronal function
While the harmful effects of amyloid peptide aggregates observed in Alzheimer's disease are well established, the mechanism through which they act on brain cells remains ill-defined. Researchers from CNRS and universite de Bordeaux have just revealed that they alter the usual functioning of connections between neurons by interacting with a key enzyme of synaptic plasticity. The results will be published on June 12, 2018 in the journal Cell Reports. (2018-06-12)

Making mistakes while studying actually helps you learn better
Contrary to popular belief, when a person makes a mistake while learning, it improves their memory for the right information, but only if the error is close to the correct answer, according to a study published in the journal, Memory. (2018-06-11)

McLean investigators suggest that brain circuits could unlock new psychiatric treatments
The findings of the studies highlight the complexity of brain inhibitory systems and the importance of taking a subtype-, circuit- and neuronal population-specific approach to develop future therapeutic strategies using cell type-specific drug delivery. (2018-06-11)

Left ventricular systolic function after pulmonary valve replacement
In the current issue of Cardiovascular Innovations and Applications (Volume 3, Number 1, 2018, pp. pp. 21-30(10); DOI 10.15212/CVIA.2017.0050), Ali N. Zaidi and W. Aaron Kay from Columbus Ohio Adult Congenital Heart Disease Program, The Ohio State University, Columbus, OH, US consider how following reparative surgery for tetralogy of Fallot or critical pulmonary stenosis (PS), patients frequently present with severe right ventricular (RV) volume overload due to pulmonary regurgitation, resulting in decreased RV function. (2018-06-10)

Study: Larger sample sizes needed to increase reproducibility in neuroscience studies
Small sample sizes in studies using functional MRI to investigate brain connectivity and function are common in neuroscience, despite years of warnings that such studies likely lack sufficient statistical power. A new analysis reveals that task-based fMRI experiments involving typical sample sizes of about 30 participants are only modestly replicable. This means that independent efforts to repeat the experiments are as likely to challenge as to confirm the original results. (2018-06-07)

Understanding how drug reduces confusion in older patients after surgery may lead to better care
A drug that reduces delirium in postoperative patients may work by preventing the overactivity of certain receptors in brain cells, according to a new study published in the Online First edition of Anesthesiology, the peer-reviewed medical journal of the American Society of Anesthesiologists (ASA). The researchers say the findings could lead to more widespread use of the drug, dexmedetomidine, and speed the development of new treatments for postoperative delirium with fewer side effects. (2018-06-07)

Active HIV in large white blood cells may drive cognitive impairment in infected mice
An experimental model of HIV infection in mice, developed by Mount Sinai researchers, has shown that HIV causes learning and memory dysfunction, a cognitive disease that is now observed in about half of HIV infected people that worsens with age, and is currently incurable. (2018-06-07)

A typical communication pattern of people with Alzheimer's disease
A research group from Kumamoto University, Japan has performed the first statistical analysis of (2018-06-06)

Human drug addiction behaviors tied to specific impairments in 6 brain networks
Systematic review of task-related neuroimaging studies found addicted individuals demonstrate increased activity in these networks during drug-related processing but decreases across all other functions. (2018-06-06)

Poor sleep linked to lower cognitive functioning in people with diabetes and prediabetes
A study published in the journal Acta Diabetologica reports that people with diabetes and prediabetes who have lower sleep efficiency -- a measure of how much time in bed is actually spent sleeping -- have poorer cognitive function than those with better sleep efficiency. (2018-06-06)

Is a stress shot on the horizon?
Rats immunized weekly for three weeks with beneficial bacteria showed increased levels of anti-inflammatory proteins in the brain, more resilience to the physical effects of stress, and less anxiety-like behavior. If replicated in humans, researchers say the findings could lead to novel microbiome-based immunizations for mood disorders like anxiety and PTSD. (2018-06-06)

Decades of type 1 diabetes linked to mild drop in cognition
People who live with type 1 diabetes for very long duration show signs of mild decreases in cognitive abilities, primarily in memory, compared to those who don't have the disease, Joslin Diabetes Center researchers have shown. (2018-06-05)

Why do some sleep-deprived people experience worse cognitive functioning than others?
The key to predicting how someone is affected by sleep loss may be found in microRNAs (miRNAs), according to a new study from researchers at the Perelman School of Medicine at the University of Pennsylvania. (2018-06-03)

Social ties could preserve memory, slow brain aging
A strong social network could be the key to preserving memory. New research from The Ohio State University found that mice housed in groups had better memories and healthier brains than animals that lived in pairs. (2018-05-31)

Single protein on-off switch controls learning flexibility and acquisition of new memories
Scientists have for the first time shown how a single molecule expressed in the brain affects how we learn new tasks and acquire new memories. The discovery has profound implications for understanding why some older people, including those living with dementia and those with neurodegenerative conditions such as Alzheimer's, struggle in remembering recent facts (short-term memory) and adapting to new tasks. (2018-05-31)

Mothers with high emotional, cognitive control help their children behave
A new parenting study finds that the greater emotional control and problem-solving abilities a mother has, the less likely her children will develop behavioral problems, such as throwing tantrums or fighting. (2018-05-31)

Memory depends on protein 'off-switch', researchers find
Memory, learning and cognitive flexibility depend on a protein 'off-switch' in the brain, according to a breakthrough discovery made by an international research collaboration co-led by the University of Warwick. (2018-05-31)

For anxiety, a single intervention is not enough
No matter which treatment they get, only 20 percent of young people diagnosed with anxiety will stay well, UConn Health researchers report. The study followed 319 young people aged 10 to 25 who had been diagnosed with separation, social, or general anxiety disorders. They received evidence-based treatment, and then had follow-ups with the researchers every year for four years. This is the first study to reassess youth treated for anxiety every year for four years. (2018-05-31)

Insomnia is a likely long-term side effect of stroke
Stroke patients experience sustained problems with insomnia potentially reducing their ability to relearn key skills and putting them at increased risk of depression, a new study in the journal Scientific Reports finds. (2018-05-30)

Hormone therapy may lead to improved cognitive function
Hormones affect just about everything that goes on in a woman's body, from reproductive function and sexual libido to weight gain and overall mood. A new study shows how, in the right dosage and combination, hormones also may slow cognitive decline in postmenopausal women as they age. The study is being published online today in Menopause, the journal of The North American Menopause Society. (2018-05-30)

E. coli infection induces delirium in aging rats
Activation of the immune system by an infection may temporarily disrupt formation of long-term memories in healthy, aging rats by reducing levels of a protein required for brain cells to make new connections, suggests new research published in eNeuro. (2018-05-29)

Cognitive training reduces depression, rebuilds injured brain structure & connectivity after traumatic brain injury
New research from the Center for BrainHealth at The University of Texas at Dallas shows that certain cognitive training exercises can help reduce depression and improve brain health in individuals years after they have suffered a traumatic brain injury (TBI). (2018-05-29)

Genes found related to the reduction of proteins that contribute to Alzheimer's onset
Creation of a map of the molecular network in the aging brain reveals two new Alzheimer's disease target genes. (2018-05-29)

UTSA researcher studies math achievement among Hispanic high school students
A researcher at The University of Texas at San Antonio has co-authored a study examining important cognitive and non-cognitive predictors of entering science, technology, engineering and mathematics (STEM) fields for Hispanic high school students. (2018-05-24)

Kessler Foundation study compares neuropsychological tests for assessing deficits in MS
Kessler Foundation researchers compared two neuropsychological tests for assessing learning in individuals with multiple sclerosis. 'Comparing the Open Trial - Selective Reminding Test results with the California Learning Verbal Test II in Multiple Sclerosis' was published online on April 4, 2018, in Applied Neuropsychology: Adult. This is the first study to compare the two tests in the same individuals with MS. (2018-05-24)

New advances in understanding and treating intellectual disorder
Researchers at Tohoku University in Japan have investigated an intellectual disorder (ATR-X) syndrome to reveal its cause, mechanism and a potential therapeutic strategy to decrease associated cognitive impairment. (2018-05-23)

Early-life obesity impacts children's learning and memory, study suggests
A new study by Brown University epidemiologists found that children on the threshold of obesity or overweight in the first two years of life had lower perceptual reasoning and working memory scores than lean children when tested at ages five and eight. The study also indicated that IQ scores may be lower for higher-weight children. (2018-05-23)

Depression speeds up brain aging, find psychologists
Psychologists at the University of Sussex have found a link between depression and an acceleration of the rate at which the brain ages. (2018-05-23)

Young toddlers may learn more from interactive than noninteractive media
Preschoolers can learn from educational television, but younger toddlers may learn more from interactive digital media (such as video chats and touchscreen mobile apps) than from TV and videos alone, which don't require them to interact. That's the conclusion of a new article in the journal Child Development Perspectives that also notes that not all children learn to the same degree from these media. (2018-05-22)

Subtle hearing loss while young changes brain function, study finds
New research from The Ohio State University has found that young people with subtle hearing loss -- the kind they aren't even aware of -- are putting demands on their brains that typically wouldn't be seen until later in life. (2018-05-22)

Reading the minds of pilots on the fly
Wearable brain monitoring sensors allowed researchers to measure cognitive workload while aircraft pilots completed memory tasks. (2018-05-21)

Vascular risk interacts with amyloid levels to increase age-related cognitive decline
Risk factors for heart disease and stroke appear to hasten the risk of cognitive decline in normal older individuals with evidence of very early Alzheimer's-disease-associated changes in the brain. (2018-05-21)

Deep space radiation treatment reboots brain's immune system
NASA and private company SpaceX plan to send humans to Mars within the next 15 years--but need to figure out how to protect astronauts from the dangerous cosmic radiation of deep space. Now the lab of UCSF neuroscientist Susanna Rosi, PhD, has identified a potential treatment for the brain damage caused by cosmic rays--a drug that prevents memory impairment in mice exposed to simulated space radiation. The study was published May 18, 2018 in Scientific Reports. (2018-05-21)

Insufficient sleep, even without extended wakefulness, leads to performance impairments
A team of researchers from BWH have isolated the impacts of short sleep and extended wakefulness on vigilant performance decline and their results are published in PNAS. (2018-05-21)

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