Current Colon Cancer News and Events

Current Colon Cancer News and Events, Colon Cancer News Articles.
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Machine learning method identifies precancerous colon polyps
A machine learning algorithm helps accurately differentiate benign and premalignant colorectal polyps on CT colonography scans, according to a new study. (2021-02-23)

Study shows new treatment pathway to prevent and treat endometrial cancer recurrence
In a new study led by Yale Cancer Center, researchers demonstrate sex hormones and insulin growth factors are associated with recurrence risk of endometrial cancer. (2021-02-23)

New insights on how inflammatory molecule contributes to skin and pancreatic cancers
An immune molecule called interleukin-33 can act within a cell's nucleus to stimulate abnormal growth and division, ultimately resulting in cancer. Targeting interleukin-33 in the nucleus may help prevent certain cancers. (2021-02-22)

Targeting MAPK4 emerges as a promising therapy for prostate cancer
New research opens the possibility that targeting the enzyme MAPK4 in human prostate cancer might provide a novel therapeutic strategy for this disease that is the second leading cause of cancer death in American men. (2021-02-19)

Addressing the biological causes of racial disparities in prostate cancer
A new review published in Cancer Reports examines the biological differences in the development of prostate cancer across ethnicities. (2021-02-18)

Physical conditions linked to psychological distress in patients with cancer
Among patients with cancer, having additional physical comorbidities was linked with a higher risk of experiencing psychological distress. The finding comes from a Psycho-Oncology analysis of 2017 data from the National Health Survey of Spain. (2021-02-18)

TGen-led study confirms cell-free DNA in urine as potential method for cancer detection
What if a simple urine sample could detect cancer in its very earliest stages when the disease responds more favorably to treatment and improved outcomes are more likely? That was the question posed by scientists at the Translational Genomics Research Institute (TGen), who have found a way of zeroing in on early-stage cancer by analyzing short strands of cell-free DNA in urine. Their study's findings were published today in the scientific journal Science Translational Medicine. (2021-02-18)

Genotoxic E. coli 'caught in the act'
Max Planck researchers and their collaborators reveal transformation of colon organoids in vitro. (2021-02-17)

How the immune system paves the way for SARS-CoV-2
The immune system actually wants to fight SARS-CoV-2 with antiviral signaling molecules. But a research team from Charité and MDC has now shown how such a signaling molecule can promote the replication of the virus. The results have been published in the journal EMBO Molecular Medicine. (2021-02-16)

New immunotherapy target discovered for malignant brain tumors
Scientists say they have discovered a potential new target for immunotherapy of malignant brain tumors, which so far have resisted the ground-breaking cancer treatment based on harnessing the body's immune system. The discovery, reported in the journal CELL, emerged from laboratory experiments and has no immediate implications for treating patients. (2021-02-15)

Exercise now proven to have mental health benefits for prostate cancer
New Edith Cowan University (ECU) research has found that exercise not only has physical benefits for men with prostate cancer, it also helps reduce symptoms of depression and anxiety. (2021-02-15)

Smectite promotes probiotic biofilm formation in gut for cancer immunotherapy
Orally administrating probiotics is ineffective due to the poor inhabitation of exogenous bacteria in host intestines. Chinese scientists report that smectite, a type of mineral clay and classical anti-diarrhoea drug, can promote the expansion of probiotics in the murine gut that subsequently elicits anti-tumor immune responses. Their findings suggest a novel approach to specifically enrich probiotics in the body, with high translational potential for cancer immunotherapy. (2021-02-10)

Oncotarget: Melatonin increases overall survival of prostate cancer patients
'The results of the use of melatonin drugs in palliative treatment of patients with end-stage prostate cancer are shown' (2021-02-10)

Radiation vulnerability
Exposure to radiation can wreak indiscriminate havoc on cells, tissues, and organs. Curiously, however, some tissues are more vulnerable to radiation damage than others. A new study now finds that cellular survival after radiation exposure depends on behavior of the tumor-suppressor protein p53 over time. In vulnerable tissues, p53 levels go up and remain high, leading to cell death. In tissues that tend to survive radiation damage, p53 levels oscillate up and down. (2021-02-09)

Samara Polytech scientists proved the anti-cancer properties of a number of plant extracts
The composition of some extracts obtained from plant raw materials was studied at Samara Polytech, and their anticarcinogenic and antioxidant properties were assessed. (2021-02-09)

Regular walnut consumption may reduce negative outcomes of H. pylori infection
A new animal study, published in the Journal of Clinical Biochemistry and Nutrition, suggests regular walnut consumption may be a promising intervention for reducing negative outcomes associated with Helicobacter pylori (H. pylori) infection, a widespread bacterial infection that affects more than half of the world's population. (2021-02-09)

New study discovers possible early detection method for elusive ovarian cancer
A study led by researchers at the University of Minnesota Medical School found a way to detect the presence of ovarian cancer in patients using Pap test samples, normally used to detect cervical cancer. (2021-02-09)

Ophiura from Russky Island might make photodynamic therapy more affordable
An unusual biologically active porphyrin compound was isolated from seabed dweller Ophiura sarsii. The substance might be used as an affordable light-sensitive drug for innovative photodynamic therapy and for targeted treatment of triple-negative breast cancer and some other cancers. Researchers from the School of Biomedicine of Far Eastern Federal University (FEFU) and the University of Geneva reported the findings in Marine Drugs. (2021-02-08)

Today's stem cell special: Small intestine on a plate!
A team of scientists from Japan have found success in growing small intestinal cells, akin to those found in the human body, from human-induced pluripotent stem cells. The scientists used a procedure they previously developed on embryonic stem cells for this discovery. They claim that the grown cells can be used for laboratory studies focusing on human small intestinal drug transport and metabolism. (2021-02-05)

Fecal microbiota transplants help patients with advanced melanoma respond to immunotherapy
For patients with cancers that do not respond to immunotherapy drugs, adjusting the composition of microorganisms in the intestines--known as the gut microbiome--through the use of stool, or fecal, transplants may help some of these individuals respond to the immunotherapy drugs, a new study suggests. Researchers at the NCI, part of the National Institutes of Health, conducted the study in collaboration with investigators from UPMC Hillman Cancer Center at the University of Pittsburgh. (2021-02-04)

Researchers assess cognitive impairment in patients with breast cancer
A recent analysis of published studies in Psycho-Oncology estimates that one-quarter of adults with breast cancer have cognitive impairment before starting therapy. (2021-02-03)

More than half of cancer survivors have underlying medical conditions associated with severe COVID
New study finds more than half (56.4%) of cancer survivors in the United States reported having additional underlying medical conditions associated with severe COVID-19 illness. (2021-02-03)

Study shows aspirin before a diagnosis may lower colorectal cancer mortality
A new study finds that long-term aspirin use before a diagnosis of colorectal cancer (CRC) may be associated with lower CRC-specific mortality. (2021-02-02)

Surgery to heal inflamed gut may create new target for disease
A surgical procedure meant to counter ulcerative colitis, an immune disease affecting the colon, may trigger a second immune system attack, a new study shows. (2021-02-02)

Delaying colonoscopy following abnormal stool test increases risk of colorectal cancer
A new VA study finds that delays in undergoing colonoscopy following an abnormal stool test increase the risk of a colorectal cancer diagnosis and cancer-related death. The findings showed the risk of colorectal cancer-related death increased by up to 1.5 times when colonoscopy was delayed more than 19 months. (2021-02-02)

Year delay between abnormal, at-home screening and colonoscopy increases cancer risk
A new study by researchers at University of California San Diego School of Medicine found delayed time between abnormal stool-based screening and subsequent colonoscopy was associated with an increased risk of a cancer diagnosis and death from colorectal cancer. (2021-02-02)

Researchers discover mechanism to overcome drug-resistance in leukemia
In a new study led by Yale Cancer Center, researchers have discovered a novel metabolic gatekeeper mechanism for leukemia. This mechanism depends on a molecule called PON2, which could lead to a new treatment for the disease. The findings were published online today in the Proceedings of the National Academy of Sciences. (2021-02-01)

Study finds potential therapeutic targets to inhibit colorectal cancer progression
Nagoya University researchers and colleagues have revealed that colorectal cancer tissues contain at least two types of fibroblasts, namely, cancer-promoting fibroblasts and cancer-restraining fibroblasts, and that the balance between them is largely involved in the progression of colorectal cancer. Their findings suggest that artificially altering the balance between the two types of cells could curb the spread of colorectal cancer tumors, which may become an effective strategy for preventing cancer progression. (2021-01-30)

Scientists spotted RPS-12 protein as a potential target for anti-cancer therapy
Using the developing eye of the fruit fly as a test platform, researchers found that RPS-12 protein overproduction appears to trigger triple-negative breast cancer and possibly some other malignancies. The protein indirectly switches on an important inracellular signaling pathway active while the embryo develops and shut down in healthy cells of adults. Far Eastern Federal University (FEFU), the University of Geneva, and the Institute of Protein Research (Russia) scientists addressed the problem in Scientific Reports. (2021-01-29)

Our gut-brain connection
MIT researchers developed an 'organs-on-a-chip' system that replicates interactions between the brain, liver, and colon. They modeled the influence microbes living in the gut have on both healthy brain tissue and tissue samples derived from patients with Parkinson's disease. (2021-01-29)

A new study reveals an "Achilles heel" of cancer cells
? For the first time, a study shows how an abnormal number of chromosomes (aneuploidy) - a unique characteristic of cancer cells that researchers have known about for decades - can become a vulnerability of these cells. ? The study could lead, in the future, to the development of drugs that will use this trait to eliminate cancer. (2021-01-27)

New Tel Aviv University study reveals 'Achilles' heel' of cancer cells
A new study from Tel Aviv University (TAU) shows, for the first time, how an abnormal number of chromosomes (aneuploidy) -- a unique characteristic of cancer cells that researchers have known about for decades -- could become a weak point for these cells. The study could lead to the development of future drugs that will use this vulnerability to eliminate the cancer cells. (2021-01-27)

Cancer deaths attributable to cigarette smoking in 152 US metropolitan and micropolitan areas
A new study shows 4 in 10 cancer deaths are attributable to cigarette smoking in parts of the South region and Appalachia. (2021-01-26)

TGen-led study results suggest more accurate diagnostic for breast cancer
Patrick Pirrotte, Ph.D., an Assistant Professor and Director of TGen's Collaborative Center for Translational Mass Spectrometry, and an international team of researchers developed a test that can detect infinitesimally small breast cancer biomarkers that are shed into the bloodstream from cells surrounding cancer known as extracellular matrix (ECM), according to the findings of their study recently published in the scientific journal Breast Cancer Research. (2021-01-26)

University of Cincinnati research unveils possible new combo therapy for head and neck cancer
Researchers at the University of Cincinnati have tested a new combination therapy in animal models to see if they could find a way to make an already effective treatment even better. Since they're using a Food and Drug Administration-approved drug to do it, this could help people sooner than later. (2021-01-22)

Strange colon discovery explains racial disparities in colorectal cancer
The colons of African-Americans and people of European descent age differently, new research reveals, helping explain racial disparities in colorectal cancer - the cancer that killed beloved 'Black Panther' star Chadwick Boseman at only 43. (2021-01-21)

New, simplified genetic test effectively screens for hereditary cancers
Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in colon, endometrial, and other cancers. This alternative to complex, multi-step testing workflows can also determine causes of MMR deficiency often missed by current clinical tests. Their results are presented in The Journal of Molecular Diagnostics, published by Elsevier. (2021-01-21)

Study updates breast cancer risk estimates for women with no family history
A new multi-institution study led by Fergus Couch, Ph.D., a Mayo Clinic pathologist, provides more accurate estimates of breast cancer risk for U.S. women who harbor inherited mutations in breast cancer predisposition genes. The findings of the CARRIERS Consortium study, published Jan. 20 in The New England Journal of Medicine, may allow health care providers to better assess the risk of breast cancer in women ? many of whom have no family history of breast cancer. (2021-01-21)

Reviving exhausted immune cells to fight cancer
Eliminating a single gene can turn exhausted cancer-fighting immune cells known as CD8+ T cells back into refreshed soldiers that can continue to battle malignant tumors, a new study led by UT Southwestern researchers suggests. The findings, published online this week in the Journal for Immunotherapy of Cancer, could offer a new way to harness the body's immune system to attack cancers. (2021-01-20)

Target of new cancer treatment valid for breast as well as blood cancers: study
Newly published research shows that a new anti-cancer drug developed at the University of Alberta, set to begin human trials this year, may work against breast cancer as well as blood cancer. (2021-01-20)

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