Current Colorectal Polyps News and Events

Current Colorectal Polyps News and Events, Colorectal Polyps News Articles.
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Machine learning method identifies precancerous colon polyps
A machine learning algorithm helps accurately differentiate benign and premalignant colorectal polyps on CT colonography scans, according to a new study. (2021-02-23)

Hospital hygiene: A closer look reveals realistic frequency of infection
A research team led by Inselspital, Bern University Hospital and the University of Bern found a correlation between the frequency of infections after surgery and performance in quality audits. Lower surgical site infection rates correlate with a lower audit score. In other words, looking more closely reveals more reported infections. Recommendations for possible correction are presented. (2021-02-18)

Genotoxic E. coli 'caught in the act'
Max Planck researchers and their collaborators reveal transformation of colon organoids in vitro. (2021-02-17)

Role of diet in risk of colorectal cancer
Researchers examined the strength of the evidence from published meta-analyses of observational studies that looked at the association between diet and the risk of colorectal cancer. (2021-02-16)

Liquid biopsy for colorectal cancer could guide therapy for tumors
A new study from Washington University School of Medicine in St. Louis demonstrates that a liquid biopsy examining blood or urine can help gauge the effectiveness of therapy for colorectal cancer that has just begun to spread beyond the original tumor. Such a biopsy can detect lingering disease and could serve as a guide for deciding whether a patient should undergo further treatments due to some tumor cells evading an initial attempt to eradicate the cancer. (2021-02-12)

Take-at-home tests boost colorectal cancer screening 10x for the underserved
By making it the default to send colorectal cancer screening tests to patients' homes unless they opted out via text message, screening rates increased by more than 1,000 percent (2021-02-08)

Study shows aspirin before a diagnosis may lower colorectal cancer mortality
A new study finds that long-term aspirin use before a diagnosis of colorectal cancer (CRC) may be associated with lower CRC-specific mortality. (2021-02-02)

Delaying colonoscopy following abnormal stool test increases risk of colorectal cancer
A new VA study finds that delays in undergoing colonoscopy following an abnormal stool test increase the risk of a colorectal cancer diagnosis and cancer-related death. The findings showed the risk of colorectal cancer-related death increased by up to 1.5 times when colonoscopy was delayed more than 19 months. (2021-02-02)

Year delay between abnormal, at-home screening and colonoscopy increases cancer risk
A new study by researchers at University of California San Diego School of Medicine found delayed time between abnormal stool-based screening and subsequent colonoscopy was associated with an increased risk of a cancer diagnosis and death from colorectal cancer. (2021-02-02)

Study finds potential therapeutic targets to inhibit colorectal cancer progression
Nagoya University researchers and colleagues have revealed that colorectal cancer tissues contain at least two types of fibroblasts, namely, cancer-promoting fibroblasts and cancer-restraining fibroblasts, and that the balance between them is largely involved in the progression of colorectal cancer. Their findings suggest that artificially altering the balance between the two types of cells could curb the spread of colorectal cancer tumors, which may become an effective strategy for preventing cancer progression. (2021-01-30)

New technique identifies important mutations behind Lynch Syndrome
A Michigan Medicine team describes a method for screening so-called genetic variants of uncertain significance in the hopes of identifying those mutations that could cause cancer. (2021-01-29)

Post-surgery death rates higher among cancer patients in lower-income countries
Research by an international team of medical experts has found cancer patients could be up to four times more likely to die following cancer surgery in low to lower-middle income countries than in high-income countries. It also revealed lower-income countries are less likely to have post-operative care infrastructure and oncology services. (2021-01-25)

Does aspirin lower colorectal cancer risk in older adults? It depends on when they start.
A new study has found that there is no protection against colorectal cancer if people begin taking aspirin regularly after age 70. However, there appears to be such protection if aspirin is started before age 70 and continued. (2021-01-21)

Strange colon discovery explains racial disparities in colorectal cancer
The colons of African-Americans and people of European descent age differently, new research reveals, helping explain racial disparities in colorectal cancer - the cancer that killed beloved 'Black Panther' star Chadwick Boseman at only 43. (2021-01-21)

New, simplified genetic test effectively screens for hereditary cancers
Researchers have developed a new integrated genetic/epigenetic DNA-sequencing protocol known as MultiMMR that can identify the presence and cause of mismatch repair (MMR) deficiency in a single test from a small sample of DNA in colon, endometrial, and other cancers. This alternative to complex, multi-step testing workflows can also determine causes of MMR deficiency often missed by current clinical tests. Their results are presented in The Journal of Molecular Diagnostics, published by Elsevier. (2021-01-21)

Simple, cheap test can help save lives from colorectal cancer
New research has demonstrated that a simple, cheap test can help identify who is at risk of developing colorectal cancer, aiding early diagnosis and potentially saving lives. (2021-01-18)

New research in JNCCN highlights dangerous disparities for life-saving cancer screening
New research in the January 2021 issue of JNCCN--Journal of the National Comprehensive Cancer Network finds more than a third of eligible people miss timely screening tests for colorectal cancer and at least a quarter appear to miss timely screening tests for breast and cervical cancers. (2021-01-13)

Record drop in cancer mortality for second straight year due to improved lung cancer treatment
Overall cancer death rates in the United States dropped continuously from 1991 through 2018 for a total decrease of 31%, including a 2.4% decline from 2017 to 2018. (2021-01-12)

Researchers engineer novel disease model to identify potential targets for ulcerative colitis drugs
As reported in Nature Communications, researchers from Cleveland Clinic's Lerner Research Institute have developed a novel, patient-derived model of ulcerative colitis, which will help advance studies into new treatments for the chronic inflammatory bowel disease. The team used the model to identify a promising target that could be inhibited to slow disease progression. (2021-01-11)

Triple chemotherapy combination improves metastatic colorectal cancer outcomes
Researchers from SWOG Cancer Research Network, a cancer clinical trials group funded by the National Cancer Institute (NCI), part of the National Institutes of Health, have shown that a triple drug combination -- of irinotecan, cetuximab, and vemurafenib -- is a more powerful tumor fighter and keeps people with metastatic colon cancer disease free for a significantly longer period of time compared with patients treated with irinotecan and cetuximab. (2020-12-23)

SU2C research leads to FDA approval of new first-line treatment for colorectal cancer
The FDA recently approved the immunotherapy drug pembrolizumab as a first-line treatment for patients with certain types of advanced colorectal cancer. This is the 9th FDA approval supported by Stand Up To CancerĀ® (SU2C) research. Patients newly diagnosed with advanced or metastatic microsatellite instability-high (MSI-H) or mismatch repair deficient (dMMR) colorectal cancer previously would have been prescribed pembrolizumab only after exhausting standard chemotherapy treatments. (2020-12-16)

Uniquely human gene may drive numerous cancers
A new study published in FASEB BioAdvances reveals a human-specific connection between advanced carcinomas and a gene called SIGLEC12. (2020-12-09)

Evolution may be to blame for high risk of advanced cancers in humans
UC San Diego researchers discovered that most people no longer produce the Siglec-12 protein, but some of those who do are at twice the risk for advanced cancer. (2020-12-09)

Hot spots identified for colorectal cancer mortality rates among young women
Women diagnosed with early-onset colorectal cancer have a greater risk of dying from the disease depending upon their county of residence, according to a study published in Clinical and Translational Gastroenterology. (2020-11-23)

Patients strongly favor banning bacon in hospitals, according to new survey
Most hospitalized patients favor eliminating processed meats--including bacon, deli meat, and sausage--from hospital menus to reduce cancer risk, according to a new survey published in the Journal of Hospital Management and Health Policy. (2020-11-18)

Certain CBD oils no better than pure CBD at inhibiting certain cancer cell lines
Cannabidiol (CBD) oils are equally or less effective at inhibiting the growth of certain cancer cells compared to pure CBD, according to Penn State College of Medicine researchers. The results of their recent study indicate that future research into the clinical applications of cannabinoids should include an analysis of whether the pure cannabinoid compound or intact plant material is more effective at achieving the therapeutic effect. (2020-11-17)

Singapore scientists identify potential new biomarker to better personalize cancer therapy
Testing for mutations in RNF43, a protein that affects key cancer cell-growth pathway Wnt, gives clinicians actionable insights to tailor treatments better. (2020-11-13)

New prognostic markers for colon cancer identified
The study recently published by MedUni Vienna and collaborative partners nominates ILSs as novel prognostic players orchestrating the pathobiology of metastatic colorectal cancer. (2020-11-11)

Predicting colorectal cancer risk among average risk persons
Regenstrief Institute and Indiana University School of Medicine research scientists have developed and tested one of the first U.S.-based models to predict personal risk for advanced precancerous polyps and colon cancer in average risk individuals. (2020-11-10)

New cancer drugs saved over 1.2 million people in the US over 16 years, new study shows
More than 1.2 million people in the US prevented facing death following a cancer diagnosis, between the year 2000 and 2016, thanks to ever improving treatment options -- a large new national study shows. (2020-11-09)

Experts release new management strategies for malignant colorectal polyps
Early identification and removal of cancerous colorectal polyps is critical to preventing the progression of colorectal cancer and improving survival rates. The U.S. Multisociety Task Force on Colorectal Cancer has released new guidance for endoscopists on how to assess colorectal lesions for features associated with cancer, discuss how these factors guide management, and outline when to advise surgery after malignant polyp removal. (2020-11-04)

Every month delayed in cancer treatment can raise risk of death by around 10%
People whose treatment for cancer is delayed by even one month have in many cases a 6 to 13% higher risk of dying - a risk that keeps rising the longer their treatment does not begin - suggests research published online in The BMJ. (2020-11-04)

Scientists discover second key pathway in colon cancer stem cell growth
Scientists have discovered a link between two key signaling pathways crucial to the development and growth of colon cancer. The scientists identified the link between the retinoic acid or RA signaling pathway and another pathway critical to tumor development, called the Wingless-related integration site or WNT pathway. WNT signaling gone wrong is associated with numerous cancers, likely contributing to drug resistance and tumor recurrence. (2020-10-28)

Low quantity and quality of muscle predicts poor outcomes in colon cancer surgery
New study suggests interventions to help patients build muscle before surgery may improve their outcomes (2020-10-27)

Targeted inhibitor of mutated KRAS gene shows promise in lung, bowel, & other solid tumors
A novel agent that targets a mutated form of the KRAS gene - the most commonly altered oncogene in human cancers and one long considered ''undruggable'' - shrank tumors in most patients in a clinical trial with manageable side effects, researchers reported today at the 32nd EORTC-NCI-AACR Symposium on Molecular Targets and Therapeutic, which is taking place online. (2020-10-25)

Inhibitor of KRAS gene mutation shows promise in lung, bowel and other solid tumors
New results from a clinical trial of a drug that targets a cancer-causing mutation in the KRAS gene have shown that it can shrink tumours and is well-tolerated by patients. In two presentations to the 32nd EORTC-NCI-AACR cancer symposium, researchers involved in the KRYSTAL-1 phase I/II clinical trial said that adagrasib (MRTX849) showed clinical activity and manageable adverse side effects in patients with non-small cell lung cancer, colorectal cancer and other solid tumours. (2020-10-25)

Easy home cancer test means patients can avoid hospital for colonoscopies
Findings from the largest international research study found that using FIT is almost 100% accurate at ruling out bowel cancer in patients with suspicious symptoms. During COVID, cancer diagnostics services were suspended and continue to be disrupted. Clinicians in London, along with NHS England, London region, agreed to rapidly implement the use of the same easy home test used in the bowel cancer screening programme, the FIT (faecal immunochemical test), to rule out cancer in people with suspected symptoms. (2020-10-23)

Thymoquinone induces apoptosis & DNA damage in 5-Fluorouracil-resistant colorectal cancer
Volume 11, Issue 31 from @Oncotarget reported that TQ decreased the expression levels of colorectal stem cell markers CD44 and Epithelial Cell Adhesion Molecule Ep CAM and proliferation marker Ki67 in colonospheres derived from both cell lines and reduced cellular migration and invasion. (2020-10-22)

Tel Aviv University researchers discover molecular link between diet and risk of cancer
An international team of researchers has identified a direct molecular link between meat and dairy diets and the development of antibodies in the blood that increase the chances of developing cancer. This connection may explain the high incidence of cancer among those who consume large amounts of dairy products and red meat, similar to the link between high cholesterol and an increased risk of heart disease. (2020-10-22)

Study reveals disparities in access to high-quality surgical care
Among U.S. patients diagnosed with breast, prostate, lung, or colorectal cancer from 2004 to 2016, those who were uninsured or had Medicare or Medicaid were less likely than privately insured patients to receive surgical care at high-volume hospitals. The findings are published in CANCER, a peer-reviewed journal of the American Cancer Society (ACS). (2020-10-21)

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