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Current Cord Blood News and Events, Cord Blood News Articles.
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Study on use of umbilical cord vs. biocellulose film for antenatal spina bifida repair
In a study to be presented on Feb. 5 in an oral plenary session at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting™, in Atlanta, researchers will present findings from a study titled, 'Cryopreserved Human Umbilical Cord (HUC) vs. Biocellulose Film (BCF) for Antenatal Spina Bifida Repair.' (2016-02-01)

New therapy halts progression of Lou Gehrig's disease in mice
Researchers announced today that they have essentially stopped the progression of amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, for nearly two years in one type of mouse model used to study the disease -- allowing the mice to approach their normal lifespan. The findings are compelling and promising, scientists say. (2016-01-28)

New findings point to central nervous system role in painful diabetic peripheral nerve disease
Emerging evidence suggests that the central nervous system is a key contributor to the problem of painful peripheral nerve disease in people with diabetes, according to a special article in the February issue of PAIN®, the official publication of the International Association for the Study of Pain. The journal is published by Wolters Kluwer. (2016-01-27)

Alzheimer-type brain pathology after transplantation of dura mater
Up to now Alzheimer's disease has not been recognized as transmissible. Now researchers at the University of Zurich and the Medical University Vienna demonstrated Alzheimer-type pathology in brains of recipients of dura mater grafts who died later from Creutzfeldt-Jakob disease. (2016-01-26)

UAB researchers find protein that improves mobility after spinal cord injuries
An international team of scientists coordinated by UAB and CIBERNED researcher Rubén López Vales has established that interleukin-37 (IL-37), a cytokine belonging to the interleukin-1 family, promotes locomotor recovery in acute spinal cord injuries. (2016-01-22)

Most cases of brain-damaged newborns not due to mismanaged deliveries
A Loyola University Medical Center study is providing new evidence that the vast majority of babies who are born with severe brain damage are not the result of mismanaged deliveries. (2016-01-22)

National Marrow Donor Program/Be The Match forms new cellular therapies subsidiary
The National Marrow Donor Program®/Be The Match®, the national organization that connects patients with their donor match for a life-saving bone marrow or umbilical cord blood transplant, today announced the formation of Be The Match BioTherapiesSM, a subsidiary that will focus on partnering with organizations pursuing new life-saving treatments in cellular therapy. (2016-01-22)

60 genetic disorders affect skin and nervous system
At least 60 genetic diseases called neurocutaneous disorders involve the skin, central nervous system, and/or peripheral nervous system, Loyola University Medical Center neurologists report. (2016-01-21)

Clarifying the mechanism for making blood cells
In 1917, Florence Sabin, the first female member of the US National Academy of Sciences, discovered hemangioblasts, the common precursor cells for blood cells and blood vessel endothelia. Her discovery faced a great deal of critical opinions, but by the end of the 20th century, those opinions were overcome, and the existence of hemangioblasts had at long last come to be acknowledged. (2016-01-20)

New biomarkers for improved treatment of severe heart and lung disease
New blood biomarkers reflecting vasoreactivity in lung blood vessels of patients with heart and lung disease, can lead to simplified diagnostics and better evaluation of treatment for patients with the condition pulmonary arterial hypertension. This is according to a doctoral dissertation at Umeå University in Sweden. (2016-01-18)

Researchers discover key pathway involved in blood vessel occlusion
Researchers have made a breakthrough in understanding blood vessel occlusion by discovering a novel pathway involved in this process. (2016-01-14)

New role for motor neurons discovered
Researchers from Sweden´s Karolinska Institutet have demonstrated a new, direct signalling pathway through which motor neurons influence the locomotor circuits that generate rhythmic movements. The findings could change the view of the role of motor neurons, and are presented in the journal Nature. (2016-01-13)

Food allergy linked to hyperactive immune system at birth
A study of more than 1,000 Victorian babies has shown those with hyperactive immune cells at birth, detected in their cord blood, were more likely to develop food allergies in their first year of life. (2016-01-13)

Source of stem cells used for bone marrow failure treatment varies worldwide
Ayami Yoshimi, M.D., Ph.D., of the University of Freiburg, Germany, and colleagues examined the use of peripheral blood stem cells and bone marrow as stem cell sources for hematopoietic stem cell transplantation in patients with bone marrow failure worldwide and factors associated with the use of each stem cell source. The study appears in the Jan. 12 issue of JAMA. (2016-01-12)

Brain's immune cells key to maintaining blood-brain barrier
New research shows that the cells responsible for protecting the brain from infection and inflammation are also responsible for repairing the system of defenses that separates the brain from the rest of the body. These findings have significant clinical implications because certain cardiovascular drugs could possibly impede the brain's ability to repair itself after a stroke or other injury. (2016-01-11)

Kessler Foundation and NJIT secure $5M grant to study wearable robots
A joint team from Kessler Foundation and the New Jersey Institute of Technology (NJIT) is developing new applications for wearable robotic exoskeleton devices with a $5 million federal grant, 'Rehabilitation Engineering Research Center (RERC) on Wearable Robots,' which funds five projects to improve mobility and independence in people with spinal cord injury, Duchenne Muscular Dystrophy, and stroke. (2016-01-07)

Powerful protein promotes post-injury regeneration and growth of injured peripheral nerves
Case Western Reserve University School of Medicine scientists have demonstrated in lab animals the regenerative dynamics of a specific signaling protein, C-C class chemokine 2 (CCL2). CCL2 sends inflammatory immune cells (macrophages) to peripheral nerve cell clusters to promote repair and to trigger gene expression that leads to new growth in nerve cells. (2016-01-05)

UW center receives $16 million to work on first implantable device to reanimate paralyzed limbs
The University of Washington-led Center for Sensorimotor Neural Engineering has received a $16 million NSF grant to develop the first implantable device to reanimate paralyzed limbs and restore motor function in stroke or spinal cord injury patients. (2015-12-29)

Not enough YAP means too much deadly inflammation inside the brain
Inside the brain, a protein called YAP, best known for its ability to help right-size our developing hearts and livers, appears to have the different but equally important task of helping control inflammation. (2015-12-22)

'Hunger hormone' may treat severe peripheral artery disease
A new study by a team of researchers from New Zealand's University of Otago and Japan suggests that the appetite-regulating hormone ghrelin could be used clinically for the early treatment of critical limb ischemia, an advanced form of peripheral artery disease. (2015-12-16)

Vessel discovery a major step toward growing kidneys
Researchers have identified the cells that give rise to the blood vessels within the kidney. It's a discovery of critical importance, as efforts to grow kidneys have long been frustrated by the inability to create the vasculature necessary for a functional organ. (2015-12-16)

Scary movies can curdle blood
Watching horror, or 'bloodcurdling,' movies is associated with an increase in the clotting protein, blood coagulant factor VIII, finds a small study in The BMJ Christmas issue this week. (2015-12-16)

DZNE scientist gets most important research award in Germany
The molecular biologist Frank Bradke, group leader at the German Center for Neurodegenerative Diseases and professor for neurobiology at the University of Bonn, will be awarded the Gottfried Wilhelm Leibniz Prize, which is endowed with 2.5 million euros. The Deutsche Forschungsgemeinschaft thereby honors his research on the growth and regeneration of neurons. (2015-12-10)

Alpha-blockers associated with d risk of stroke in older men
Older men starting α-blockers-blockers, commonly used for treating enlarged prostates, have a higher risk of ischemic stroke during the initiation phase, although this effect is not apparent in men already taking other blood pressure medications, found new research in Canadian Medical Association Journal. (2015-12-07)

Multiple myeloma patient study shows promise for natural killer cells
A first-in-human Phase I study of multiple myeloma patients combined expanded cord blood-derived natural killer cells with transplantation of a patient's own stem cells and high-dose chemotherapy with little or none of the side effects seen with current treatments. (2015-12-07)

Vanderbilt study explores spinal cord stimulation to treat paralysis
A Vanderbilt neurosurgeon is looking to recruit patients with paraplegia to investigate whether intraspinal microstimulation technology can restore complex body movements. (2015-12-03)

CWRU researchers laying groundwork for new type of pain relief
A team led by a CWRU researcher will use the National Institute of Neurological Disorders and Stroke grant to seek not only the answers to why high frequency electrical stimulation provides pain relief but lay the foundation for a new and powerful alternative treatment. (2015-12-02)

Tracing a path toward neuronal cell death
Researchers at Brigham and Women's Hospital have developed a genetic model that is yielding new insights into what happens when astrocytes go awry. (2015-11-30)

Recent Western blood pressure guidelines may boost stroke risk in Asian patients
European and North American blood pressure guidelines, issued last year, may actually boost the stroke risk if used for Asian patients, particularly the elderly, suggests an expert opinion published online in the journal Heart Asia. (2015-11-26)

Comparing therapies for a rare autoimmune disease
In the course of a study conducted throughout Germany, medical professionals have compared different treatment methods for Neuromyelitis optica, an inflammatory disease of the central nervous system. It turned out that the best results were not achieved with conventional steroid therapy. Under the auspices of the Ruhr-Universität Bochum and the Hannover Medical School, the team published their findings in the journal Annals of Neurology. (2015-11-26)

Better blood pressure control -- by mobile phone
An interactive web system with the help of your mobile phone can be an effective tool for better blood pressure control. Test persons lowered their blood pressure, were better able to understand how their lifestyle affects their blood pressure and actively participated in followup discussions. These results were shown in a doctoral thesis at the University of Gothenburg. (2015-11-25)

Immune-disorder treatment in mice holds potential for multiple sclerosis patients
A University of Florida Health researcher has found a simple, rapid way to treat an immune-related disorder in mice, an approach that could eventually help multiple sclerosis patients after further research. (2015-11-24)

Umbilical cells help eye's neurons connect
Cells isolated from the human umbilical cord have been shown to produce molecules that help retinal neurons from the eyes of rats grow, connect and survive. The findings, which appear Nov. 25 in the Journal of Neuroscience, implicate one family of molecules in particular -- thrombospondins - that may have therapeutic potential for the treatment of degenerative eye diseases. (2015-11-24)

Neuroscientists gain insight into cause of Alzheimer's symptoms
Virginia Tech Carilion Research Institute scientists have uncovered a mechanism in the brain that could account for some of the neural degeneration and memory loss in people with Alzheimer's disease. (2015-11-23)

Stem cell treatment mediates immune response to spinal cord injury in pre-clinical trials
Scientists at Case Western Reserve University School of Medicine have demonstrated in lab animals that a family of therapeutic stem cells called multipotent adult progenitor cells lessen the consequences of the immune system's damaging second wave response and preserve function that would otherwise be lost. Their findings appear in the Nov. 19 edition of Scientific Reports, an online journal from the publishers of the journal Nature. (2015-11-23)

Blood from small children 'remembers' prenatal smoking exposure
New Johns Hopkins Bloomberg School of Public Health-led research finds that blood taken from children up to the age of five contains molecular evidence about whether their mothers smoked during pregnancy. (2015-11-23)

Discovery helps explain what guides neurons to connect
In Science, a team led by Brown University neuroscientist Alexander Jaworski reports the discovery of a protein that guides neurons as they extend axons across the spinal cord midline. The finding could help unravel the complexity of how neural connections form and the understanding of diseases that result from brain mis-wiring. (2015-11-19)

A newly discovered signaling molecule helps neurons find their way in the developing brain
In the developing nervous system, some neurons must extend their branches to connect one half of the brain with the other. A new study sheds light on the molecular mechanisms that guide the winding paths of their axons. (2015-11-19)

Wisconsin scientists grow functional vocal cord tissue in the lab
University of Wisconsin-Madison scientists have succeeded in growing functional vocal cord tissue in the laboratory, a major step toward restoring a voice to people who have lost their vocal cords to cancer surgery or other injuries. Dr. Nathan Welham, a UW speech-language pathologist, and colleagues from several disciplines were able to bioengineer vocal cord tissue able to transmit sound, they reported in a study published today in the journal Science Translational Medicine. (2015-11-18)

UT Dallas researchers use vagus nerve stimulation outside the forebrain
Dr. Patrick Ganzer of the Texas Biomedical Device Center won a best paper award for work that uses vagus nerve stimulation paired with rehabilitation to enhance neuroplasticity. (2015-11-17)

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