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Current Coronary Artery Disease News and Events, Coronary Artery Disease News Articles.
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Results from the VOYAGER PAD Trial reported at TCT Connect
A large subgroup analysis of a randomized clinical trial showed neither a mortality risk nor benefit associated with the use of paclitaxel drug-coated devices (DCD) in the treatment of peripheral artery disease (PAD). The study also found that the benefit of rivaroxaban use on reducing ischemic limb and cardiovascular outcomes was consistent regardless of whether a DCD was used. (2020-10-19)

Changes in blood metabolite profile are visible years before diagnosis of alcohol-related disease
A new study from the University of Eastern Finland is the first in the world to show that the serum metabolite profile can be used to identify individuals likely at risk of developing an alcohol-related disease in the future. The finding also opens up new avenues for preventing alcohol-related adverse effects. (2020-10-19)

CVIA has just published a new issue, Volume 5 Issue 1
The journal Cardiovascular Innovations and Applications (CVIA) has just published the first issue of Volume 5. Included in the issue is a paper of major importance on Serum Procalcitonin Levels on Admission Predict Death in Severe and Critical COVID-19 Patients in Wuhan, China (2020-10-19)

Results from host-reduce-polytech-ACS trial reported at TCT Connect
A randomized clinical trial found that drug-eluting stents (DES) with durable polymers are non-inferior to DES with biodegradable polymers in patients with acute coronary syndrome (ACS). Findings were reported today at TCT Connect, the 32nd annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine. (2020-10-17)

Results from the FORECAST Trial reported at TCT Connect
In the FORECAST randomized clinical trial, the use of fractional flow reserve management derived from computed tomography (FFRCT) did not significantly reduce costs but did reduce the use of invasive coronary angiography (ICA). (2020-10-16)

Results from the TARGET FFR study reported at TCT Connect
Results from the randomized controlled TARGET FFR trial show that while a physiology-guided percutaneous coronary intervention (PCI) optimization strategy did not achieve a significant increase in the proportion of patients with final FFR ?0.90, it reduced the proportion of patients with a residual FFR ?0.80 following PCI. (2020-10-16)

Results from the DEFINE-FLOW study reported at TCT Connect
A new observational study of deferred lesions following combined fractional flow reserve (FFR) and coronary flow reserve (CFR) assessments found that untreated vessels with abnormal FFR but intact CFR do not have non-inferior outcomes compared to those with an FFR greater than 0.8 and a CFR greater than or equal to two when treated medically. (2020-10-16)

Results from the REFLECT II Trial reported at TCT Connect
The REFLECT II randomized clinical trial evaluating the safety and efficacy of a device designed to reduce cerebral embolization and ischemic stroke, complications of transcatheter aortic valve replacement (TAVR), found that the device met the primary safety endpoint compared to historical controls but did not demonstrate superiority of the device for the primary hierarchical efficacy endpoint. (2020-10-15)

Results from PROSPECT ABSORB reported at TCT Connect and published simultaneously in JACC
New data from PROSPECT ABSORB, a pilot randomized trial of percutaneous coronary intervention (PCI) of non-flow-limiting vulnerable plaques in native coronary arteries, found that PCI was safe, substantially enlarged follow-up lumen areas, and was associated with favorable long-term clinical outcomes. (2020-10-14)

Results from COMBINE (OCT-FFR) reported at TCT Connect
Data from COMBINE (OCT-FFR) found that the use of FFR combined with OCT imaging can help improve the accuracy of high-risk lesion identification in patients with diabetes. Findings were reported today at TCT Connect, the 32nd annual scientific symposium of the Cardiovascular Research Foundation (CRF). TCT is the world's premier educational meeting specializing in interventional cardiovascular medicine. (2020-10-14)

NIRS-IVUSimaging can help identify high-risk plaques that can lead to adverse outcomes
New data from the PROSPECT II study shows that NIRS-IVUS intracoronary imaging can help identify angiographically non-obstructive lesions with high-risk characteristics for future adverse cardiac outcomes. (2020-10-14)

Young women who suffer a heart attack have worse outcomes than men
Women aged 50 or younger who suffer a heart attack are more likely than men to die over the following 11 years, according to a new study published in the European Heart Journal. The study found that women were less likely to undergo therapeutic invasive procedures after admission to hospital with a heart attack or to be treated with certain medical therapies upon discharge, such as aspirin, beta-blockers, ACE inhibitors and statins. (2020-10-13)

Pulmonary artery thrombosis a complication of radiation therapy
According to ARRS' American Journal of Roentgenology, the imaging findings of in situ pulmonary artery thrombosis (PAT) associated with radiation therapy (RT) are different from those of acute pulmonary emboli and do not appear to embolize. Due to the differences in clinical prognosis and subsequent management strategies, in situ PAT associated with RT -- which has not previously been described in the English literature -- must be distinguished from pulmonary embolism. (2020-10-09)

Scientists developed key principles for creating an artificial vessel
Researchers from St. Petersburg provided a unique experiment. They implanted a polymer scaffold as a vascular prosthesis into the rat abdominal aorta and monitored the process of its bioresobtion for 16 months. An artificial vessel was formed where the scaffold was located. It posess similar characteristics as a natural vessel. (2020-10-08)

Researchers use multi-ancestry comparison to refine risk factors for coronary artery disease
An international group led by researchers from the RIKEN Center for Integrative Medical Sciences have used a combination of genome-wide association analysis--or GWAS--and a trans-ancestry comparison of different GWAS studies, to come up with a more accurate predictor of coronary artery disease based on genetic factors. (2020-10-06)

Forearm artery reveals humans evolving from changes in natural selection
Humans haven't developed genetic mutations for telepathy or superpowers just yet, but a new study shows our species is still evolving in unique ways and changes in the natural selection could be the major reason. (2020-10-06)

Influenza vaccination may provide roadmap to prevent COVID-19 in CV disease patients
Seasonal influenza vaccine development and mass production, as well as three international influenza vaccine cardiovascular outcomes trials currently underway, may inform future efforts targeted at developing and evaluating vaccine strategies for COVID-19, according to a state-of-the-art review in the Journal of the American College of Cardiology. Authors of the paper also evaluated whether existing flu trial networks could offer primary and secondary prevention strategies for patients with cardiovascular disease at risk of complications from COVID-19. (2020-10-05)

Risk of heart disease in breast cancer patients can be predicted from routine scans
Automated analysis of breast cancer patients' routine scans can predict which women have a greater than one in four risk of going on to develop cardiovascular disease, according to research presented at the 12th European Breast Cancer Conference. (2020-10-01)

Data from two Indian states reveal SARS-CoV-2 impacts in a resource-limited setting
In two states in India, Tamil Nadu and Andhra Pradesh, COVID-19 cases and deaths have been more heavily concentrated in younger cohorts than is seen in high-income countries, among other trends. (2020-09-30)

Irregular and long menstrual cycles linked to greater risk of early death
Irregular and long menstrual cycles in adolescence and adulthood are associated with a greater risk of early death (before age 70), finds a study published by The BMJ today. (2020-09-30)

Kawasaki disease is not a homogenous disease nor are its triggers
Researchers at UC San Diego report that while Kawasaki disease occurs in clusters, the traits, and thus the triggers of the inflammatory disease vary among clusters. (2020-09-29)

Prototype graft, designed to replace damaged heart vessels, shows promise in cell study
North Carolina State University researchers reported promising preclinical findings for a prototype of a vascular graft designed as a replacement for a damaged or blocked coronary artery, which supplies blood to the heart. (2020-09-29)

Study identifies weight-loss threshold for heart health in patients with obesity, diabetes
A Cleveland Clinic study shows that 5 to 10 percent of surgically induced weight loss is associated with improved life expectancy and cardiovascular health. In comparison, about 20 percent weight loss is necessary to observe similar benefits with a non-surgical treatment. The findings also show that metabolic surgery may contribute health benefits that are independent of weight loss. The study is published in the October issue of Annals of Surgery. (2020-09-23)

Large study confirms men have 62% increased risk of COVID-19 associated death, possibly related to higher degree of inflammation
New research presented at this week's ESCMID Conference on Coronavirus Disease (ECCVID, online 23-25 September) confirms that men with COVID-19 have worse outcomes than women, possibly related to them experiencing higher levels of inflammation. The study is by Dr Frank Hanses, University Hospital Regensburg, Germany, and colleagues, and shows that men have a 62% increased risk of COVID-19 associated death. (2020-09-23)

Having high cholesterol levels early in life leads to heart problems by middle age
Having elevated cholesterol during the teens or early twenties increases a person's risk of having a heart attack, stroke or other cardiovascular event during middle age. That is the finding a new landmark study led by researchers at the University of Maryland School of Medicine (UMSOM). (2020-09-22)

CHOP researchers find MIS-C associated with myocardial injury
Using sensitive parameters to assess cardiac function, researchers at Children's Hospital of Philadelphia (CHOP) have found that cardiac involvement in multisystem inflammatory syndrome in children (MIS-C) differs from Kawasaki disease (KD) and is associated with myocardial injury. The findings were published recently in the Journal of the American College of Cardiology. (2020-09-21)

Cleveland Clinic study finds no link between influenza vaccine and COVID-19 risk
Using patient data from Cleveland Clinic's COVID-19 registry, Dr. Joe Zein found that receiving the flu vaccine does not increase risk for COVID-19 or worsen associated disease outcomes, suggesting it is safe and advisable to receive the influenza vaccine this flu season. (2020-09-21)

Oral radiography can reveal chronic coronary artery disease
A study found a link between carotid artery calcification observable in radiographs and coronary artery disease as well as several oral infections. (2020-09-16)

Biologic therapy for psoriasis may reduce heart disease
Biologic therapy for psoriasis - protein-based infusions to suppress inflammation - was associated with a significant reduction in high-risk plaque in heart arteries, over one-year, according to new research. The positive association between biologic therapy and a decrease in high-risk plaque in heart arteries was significant after adjusting for cardiovascular risk factors and psoriasis severity. (2020-09-15)

Pesco-Mediterranean diet, intermittent fasting may lower heart disease risk
A Pesco-Mediterranean diet rich in plants, nuts, whole grains, extra-virgin olive oil, and fish and/or seafood is ideal for optimizing cardiovascular health, according to a cumulative review published today in the Journal of the American College of Cardiology. Intermittent fasting is recommended as part of this diet. (2020-09-14)

Uncovering the genetics behind heart attacks that surprise young, healthy women
New genetic research finds spontaneous coronary artery dissection, or SCAD, heart attacks may be more similar to different diseases than to other heart attacks. (2020-09-04)

Trial clarifies use of blood transfusion in anaemic heart attack patients
Restricting blood transfusion in anaemic heart attack patients to those with very low haemoglobin levels saves blood with no negative impact on clinical outcomes. That's the finding of the REALITY trial presented in a Hot Line session today at ESC Congress 2020. Anaemia affects approximately 5-10% of patients with myocardial infarction and is an independent predictor of cardiac events and increased mortality. (2020-09-02)

Study reveals best anti-clotting strategy after heart valve intervention
The POPular TAVI trial has challenged current guideline recommendations on antiplatelet treatment after transcatheter aortic valve implantation (TAVI) in patients not taking oral anticoagulation. The findings are presented in a Hot Line session today at ESC Congress 2020. (2020-08-31)

Angina drug fails to improve outcomes after successful revascularisation
Trimetazidine administered after successful percutaneous coronary intervention (PCI) does not improve outcomes in patients with chronic or acute coronary syndromes, according to results of the ATPCI trial presented in a Hot Line session today at ESC Congress 2020. (2020-08-31)

Gout drug repurposed to fight heart disease
Colchicine reduces the risk of major cardiovascular events in patients with chronic coronary disease, according to results of the LoDoCo2 trial presented in a Hot Line session today at ESC Congress 2020.1 ''Over a decade, more than one in three heart patients will have another heart attack or stroke, or die from heart disease, despite taking preventive medication,'' said study author Dr. Mark Nidorf of GenesisCare, Australia. (2020-08-31)

Common medicine used to treat gout found to prevent progression of coronary disease
A major clinical trial involving 5,500 patients in Australia and the Netherlands found heart attacks and the need for coronary stenting or bypass surgery reduced by 30% in patients taking low dose colchicine, an old and widely available drug commonly used to treat gout. (2020-08-31)

Study provides hope for young women after heart attack
Premenopausal women have good long-term outcomes after a heart attack, according to late breaking research presented today at ESC Congress 2020. (2020-08-30)

Can people with heart disease exercise safely?
The first recommendations on sports and physical activity in all types of heart disease are launched today by the European Society of Cardiology (ESC). The document is published online in European Heart Journal, and on the ESC website. ''With rising levels of obesity and sedentary lifestyles, promoting physical activity is more crucial now than ever before,'' said Professor Antonio Pelliccia, Chairperson of the guidelines Task Force and chief of cardiology, Institute of Sports Medicine and Science, Rome, Italy. (2020-08-29)

How to treat the most common heart attacks
One in five patients die within a year after the most common type of heart attack. European Society of Cardiology (ESC) treatment guidelines for non-ST-segment elevation acute coronary syndrome are published online today in European Heart Journal, and on the ESC website. (2020-08-29)

How to treat high blood pressure without ruining your sex life
Men with untreated high blood pressure have poorer penile blood flow than those with normal blood pressure, according to research presented today at ESC Congress 2020.1 The differences disappeared with blood pressure medication. The results provide reassurance to men concerned about the effects of blood pressure-lowering medications. (2020-08-28)

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