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Current Cystic Fibrosis News and Events, Cystic Fibrosis News Articles.
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UNC researchers find genetic trigger for RSV-induced infant hospitalizations
Researchers at UNC School of Medicine have pinpointed a viral protein that plays a major role in making respiratory syncytial virus the most common cause of hospitalization in children under one year of age. (2014-04-08)

Montreal researchers explain how our immune system kills abnormal blood cells
A team of researchers at the IRCM, led by Andre Veillette, M.D., explains how our immune system kills abnormal blood cells. Their discovery, recently published in the Journal of Experimental Medicine, could eventually lead to new treatment avenues for leukemia, lymphoma and certain types of infectious viral diseases. (2014-04-08)

Antibiotic resistance enzyme caught in the act
NpmA is a mobile gene in bacteria that confers resistance to aminoglycoside antibiotics. Structural biologists analyze the threat NpmA poses and reveal targets for drug development. (2014-04-07)

Flipping the switch on scleroderma
Scleroderma is a rare and often fatal disease, causing the thickening of tissue, that currently lacks a cure and any effective treatments. A group of researchers, including a Michigan State University professor, is looking to change that. (2014-04-04)

Quality improvement initiative leads to reduction in unnecessary follow-up imaging
The April issue of the Journal of the American College of Radiology focuses on a variety of issues relating to clinical practice, practice management, health services and policy, and radiology education and training. (2014-04-01)

Can antibiotics cause autoimmunity?
A certain class of antibiotics prompts cells to produce low levels of novel self proteins that could trigger an autoimmune disease. (2014-03-31)

IRCM researchers uncover a new function for an important player in the immune response
Institut de recherches cliniques de Montréal researchers led by Javier M. Di Noia, Ph.D., uncovered a new function of AID, a crucial enzyme for the immune response. The discovery, recently published by the scientific journal Proceedings of the National Academy of Sciences, helps explain a rare genetic disorder that causes an immunodeficiency syndrome. (2014-03-27)

New method can diagnose a feared form of cancer
Pancreatic cancer is often detected at a late stage, which results in poor prognosis and limited treatment options. Researchers at The University of Gothenburg, Sweden, have now developed a method which identifies the cancer's visible precursors with 97 percent certainty. The method, which is expected to aid in the early discovery of the cancer as well as minimize the risk of unnecessary surgery, may be introduced in patient care within five years. (2014-03-21)

CF Foundation and CF care expert partnership yields striking progress for people with cystic fibrosi
A decade of strategic efforts to improve care has had a key role in improving quality of life and added years to predicted survival for people with cystic fibrosis in the United States, according to the editors of a BMJ Quality & Safety supplement dedicated to the disease. (2014-03-17)

New research links body clocks to chronic lung diseases
The body clock's natural rhythm could be utilized to improve current therapies to delay the onset of chronic lung diseases. (2014-03-17)

Hepatitis C remains major problem for HIV patients despite antiretroviral therapy
A new study led by researchers at the Perelman School of Medicine at the University of Pennsylvania has found that the risk of hepatitis C-associated serious liver disease persists in HIV patients otherwise benefiting from antiretroviral therapy to treat HIV. (2014-03-17)

Ben-Gurion U. researchers identify severe genetic disease prevalent in Moroccan Jews
One of every 37 Moroccan Jews carries one of the two mutations and based on the high carrier rate, PCCA2 is the most common severe genetic disease in Moroccan Jews discovered to date. Fifteen percent of Israel's total population (1 million people) is of Moroccan ancestry. Nearly 100,000 Moroccan Jews also live in the United States, largely in New York City, Washington, D.C., Boston and Florida. (2014-03-10)

Research benefits surgeons making decisions on how to help their patients breathe easier
UC researchers use computer simulations developed for aircraft design to improve treatment of human airways. (2014-03-04)

Ancient Chinese medicine put through its paces for pancreatic cancer
The bark of the Amur cork tree has traveled a centuries-long road with the healing arts. Now it is being put through its paces by science in the fight against pancreatic cancer, with the potential to make inroads against several more. (2014-03-03)

Dangerous mistaken identity
Tau proteins, which are responsible for Alzheimer's disease, bind to the folding protein HSP90. The molecular recognition mechanisms that play a role here, have been unveiled by an international team of scientists led by the Technische Universitaet Muenchen and the Helmholtz Zentrum Muenchen. This might open the door for new approaches for the treatment of Alzheimer's disease, as the scientists report in the trade journal Cell. (2014-02-28)

Drinking water linked to infections
Brisbane's water supply has been found to contain disease carrying bugs which can be directly linked to infections in some patients, according to a new study by QUT. (2014-02-27)

Montreal researchers find a link between pollutants and certain complications of obesity
A team of researchers at the IRCM in Montreal led by Remi Rabasa-Lhoret, in collaboration with Jerome Ruzzin from the University of Bergen in Norway, found a link between a type of pollutants and certain metabolic complications of obesity. Their breakthrough, published online this week by the Journal of Clinical Endocrinology & Metabolism, could eventually help improve the prevention, diagnosis, and treatment of cardiometabolic risk associated with obesity, such as diabetes, hypertension and cardiovascular disease. (2014-02-27)

Discovery of a 'conductor' in muscle development
A team led by Jean-Francois Cote, researcher at the IRCM, identified a 'conductor' in the development of muscle tissue. The discovery, published online yesterday by the scientific journal Proceedings of the National Academy of Sciences, could have an important impact on the treatment of muscular diseases such as myopathies and muscular dystrophies. (2014-02-25)

Is a 'buttery' molecule behind cystic fibrosis flare-ups?
Katrine Whiteson and colleagues identified a lung-damaging molecule in higher concentrations in cystic fibrosis patients during symptom flare-ups. (2014-02-21)

Study in fruitflies strengthens connection among protein misfolding, sleep loss, and age
Pathways of aging and sleep intersect at the circuitry of a cellular stress response pathway, and that by tinkering with those connections, it may be possible to alter sleep patterns in the aged for the better -- at least in fruit flies. (2014-02-20)

Garlic counteracts virulent bacteria
Garlic contains a substance that is particularly effective in encounters with even the hardiest bacterial strains. A young researcher at the University of Copenhagen will soon be defending his Ph.D. thesis on the positive properties of the malodorous plant. (2014-02-18)

Scientific racism's long history mandates caution
Racism as a social and scientific concept is reshaped and reborn periodically through the ages and according to a Penn State anthropologist, both medical and scientific researchers need to be careful that the growth of genomics does not bring about another resurgence of scientific racism. (2014-02-14)

New therapy to stop progression of fibrosis
Scientists from the University of Sheffield have developed a novel antibody-based therapy which targets the progression of life threating kidney fibrosis. (2014-02-14)

Game changer: Biomarker identified for noncancerous pancreatic cysts
Researchers at the Indiana University School of Medicine have discovered a highly accurate, noninvasive test to identify benign pancreatic cysts. (2014-02-11)

Director of Women's Guild Lung Institute awarded grant to study treatment for lung disease
A Cedars-Sinai research team led by Paul W. Noble, MD, has been awarded $628,816 by California's stem cell agency to develop a treatment for idiopathic pulmonary fibrosis, a deadly disease that destroys the lungs and damages other vital organs. The illness, which has no cure and few effective treatments, thickens and hardens lung tissue, leaving the organs badly scarred. (2014-02-06)

Study shows potential usefulness of non-invasive measure of heart tissue scarring
Scarring of tissue in the upper chamber of the heart (atrium) was associated with recurrent rhythm disorder after treatment, according to a study in the February 5 issue of JAMA. (2014-02-04)

MRIs help predict which atrial fibrillation patients will benefit from catheter ablation
A new type of contrast MRI can predict which heart patients with atrial fibrillation are most likely to benefit from a treatment called catheter ablation, according to a landmark multi-center study published in the Journal of the American Medical Association. (2014-02-04)

Study supports 3-D MRI heart imaging to improve treatment of atrial fibrillation
A University of Utah-led study for treatment of patients with atrial fibrillation provides strong clinical evidence for the use of 3-D MRI to individualize disease management and improve outcomes. (2014-02-04)

HIV-infected teens delaying treatment until advanced disease, Johns Hopkins study shows
Nearly half of HIV-infected teenagers and young adults forego timely treatment, delaying care until their disease has advanced, which puts them at risk for dangerous infections and long-term complications, according to a study led by the Johns Hopkins Children's Center. (2014-02-03)

Researchers reverse some lung diseases in mice by coaxing production of healthy cells
Introducing proteins that direct lung stem cells to grow the specific cell types needed to repair lung injuries could lead to new ways to treat some lung diseases, according to research from Boston Children's Hospital published in the journal Cell. (2014-01-30)

Less than half of children treated for anxiety achieve long-term relief
Fewer than one in two children and young adults treated for anxiety achieve long-term relief from symptoms, according to the findings of a study by investigators from the Johns Hopkins Children's Center and five other institutions. (2014-01-29)

$7 million multi-institutional contract creates New York City Clinical Data Research Network
A $7M contract brings together seven NYC health systems to encourage data sharing and recruitment of patients for clinical trials. The funding, awarded by the Patient-Centered Outcomes Research Institute and authorized by Congress in 2010 to fund research to provide information about the best available evidence for patients and their health care providers to make more informed decisions. The award will create a Clinical Data Research Network, one of 29 such health data networks nationwide. (2014-01-28)

More benefits emerging for one type of omega-3 fatty acid: DHA
A study of the metabolic effects of omega-3 fatty acids, especially DHA, concludes that these compounds may have an even wider range of biological impacts than previously considered. They could be of significant value in the prevention of fatty liver disease, but that may also be just the beginning. (2014-01-23)

FASEB announces 2014 SRC: Polycystic Kidney Disease -- From Molecular Mechanism to Therapy
This 2014 FASEB Science Research Conference focuses on recent advances in our understanding of the pathogenic mechanisms underlying the cystic renal diseases and the development of therapies to slow down their progression. The polycystic kidney diseases are a group of inherited disorders that result not only in cyst development in the kidney, but also produce a range of extra-renal phenotypic manifestations. (2014-01-22)

UCLA life scientists, colleagues differentiate microbial good and evil
To safely use bacteria in biotechnology and agriculture, where bacteria can help to fertilize plants, understanding the differences between harmful and healthy bacterial strains is vital. One member of a family of bacteria called Burkholderiaceae is known as a potential bioterrorist agent and not used in agriculture. Can the microbial good and evil be told apart? Yes, UCLA biologists report. (2014-01-08)

UBC-VCH scientists use drug to repair rare birth defect
University of British Columbia and Vancouver Coastal Health scientists have developed a potential cure for a rare eye disease, showing for the first time that a drug can repair a birth defect. They formulated the drug Ataluren into eye drops, and found that it consistently restored normal vision in mice who had aniridia, a condition that severely limits the vision of about 5,000 people in North America. (2013-12-20)

With sinus study, Saint Louis University researchers find that harmless members of microbiome spark immune reaction
Researchers have found evidence that some chronic sinus issues may be the result of inflammation. (2013-12-19)

American Thoracic Society and the American Lung Association to co-fund research into lung disease
The American Thoracic Society Foundation and the American Lung Association announced today that they are co-funding an $80,000 grant that will support important research into the mechanisms underlying Hermansky-Pudlak syndrome, a rare inherited disease which affects a number of organs including the lungs. (2013-12-18)

Bacterium infecting cystic fibrosis patients genetically evolves to live in lungs and evade antibiotic treatments
The bacterium that's the most important pathogen in patients with cystic fibrosis (CF) has genetically evolved and adapted to survive in CF-infected lungs and evade antibiotic treatments, scientists from the University of Ottawa and the University of Calgary have shown. (2013-12-11)

Mayo Clinic: Drug induces morphologic, molecular and clinical remissions in myelofibrosis
Imetelstat, a novel telomerase inhibiting drug, has been found to induce morphologic, molecular and clinical remissions in some patients with myelofibrosis a Mayo Clinic study has found. The results were presented today at the 2013 American Society of Hematology Annual Meeting in New Orleans. (2013-12-09)

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