Current Cytokines News and Events | Page 22

Current Cytokines News and Events, Cytokines News Articles.
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Stress may increase susceptibility to infectious disease
Dozens of studies have shown that stress can alter the levels of certain biochemical markers in the body -- key players in the human immune response -- but scientists weren't sure those changes actually led to poorer health. Now, they seem convinced. (1999-07-26)

Cellular espionage at play in post-menopausal osteoporosis
Biologists at Washington University in St. Louis have shown that lower estrogen levels in post-menopausal women allow a class of inflammatory molecules called cytokines to bind to bone cell surfaces. This gives the green light for cells called osteoclasts to perform their specialty -- bone destruction. It all involves (1999-07-26)

Researchers learn how stress slows wound healing
Scientists investigating why wounds heal more slowly on patients who are stressed have found that psychological stress can increase the levels of some hormones in the blood. These hormones can slow the delivery of certain compounds -- cytokines -- to the site of the injury to start the healing process. (1999-07-26)

Studies confirm the identity of an elusive 'receptor' in human cells -- A breakthrough in the effort to understand and fight septic shock
In a study headed by researchers at Cedars-Sinai Medical Center, scientists have for the first time identified in actual human cells a (1999-06-11)

Very-Low-Fat Diet May Compromise Immune Function, Increase Infection Risk In Trained Runners, UB Study Finds
Trained runners who severely limit the amount of fat in their diets may be suppressing their immune system and increasing their susceptibility to infections and inflammation, a University at Buffalo study has shown. Researchers found that running 40 miles per week on a diet composed of approximately 17 percent fat compromised the runners' immune response. (1999-05-22)

Jefferson Researchers Report Progress In Using Vaccinia-Based Vaccine For Melanoma
The concept is straightforward: beat cancer by boosting the body's defense system. Oncologist Michael Mastrangelo and his colleagues at Jefferson Medical College have inserted a gene for an immune-system enhancing protein into the tumor cells of advanced melanoma patients, using the vaccinia virus as their vaccine vehicle. (1999-05-14)

Cedars-Sinai Medical Center Physicians And Scientists Present Findings At Annual Meeting Of The Pediatric Academic Societies
Researchers at Cedars-Sinai Medical Center are presenting three scientific lectures (hypoxic-ischemic encephalopathy, septic shock, Cole-Hughes syndrome) and several poster- session exhibits at the Pediatric Academic Societies' 1999 Annual Meeting May 1 through 4 in San Francisco. (1999-05-04)

New Study By TSRI Scientists Sheds Light On Viral Clearance In Acute Hepatitis B Infection
A study published this week by scientists at The Scripps Research Institute demonstrates a new paradigm in viral immunology, that the immune system can cure viral infections without destroying the infected cells. They conclude that nondestructive antiviral mechanisms can contribute to viral clearance by eliminating a virus from inside the cell without killing it. (1999-04-30)

Study Suggests New Approach To Asthma
Although most scientists regard immune cells as the culprit in asthma, a new study suggests that resident airway cells may be at fault. These cells contain an anti-virus alarm system which, if not turned off, triggers persistent inflammation. (1999-04-28)

Dietary Lutein Inhibits Mammary Tumor Growth And Normalizes Immune Balance In Tumor-Bearing Mice
The carotenoid antioxidant lutein can normalize immune system balance in mammary tumor-bearing mice, effectively slowing tumor growth, according to a study presented today at the Federation of American Societies for Experimental Biology 1999 annual meeting. (1999-04-18)

New Discovery May Lead To Control Of Production Of Key Proteins
Scientists are closing in on discovering the way that the body regulates critical proteins involved in the front line defense against disease as well as in normal body processes.The discoveries could lead to development of pharmaceuticals to control the body's production of these proteins. (1999-04-16)

Studies At Cedars-Sinai Confirm Identity Of An Elusive 'Receptor' In Human Cells -- A Breakthrough In Understanding, Fighting Septic Shock
In a study headed by researchers at Cedars-Sinai Medical Center, scientists have for the first time identified in actual human cells a (1999-03-30)

Real Connection Between Oral Health And Heart Disease
University of Michigan dentistry Prof. Walter Loesche suggested several possibilities why reports over the past five years have suggested a link between periodontal (gum) disease and cardiovascular disease. Loesche speaks at a symposium titled (1999-01-22)

UCSF Team Identifies Two Key Molecules In Asthma; Important Finding For New Therapies That Treat Disease At Cell Level
Researchers at the University of California San Francisco have identified two molecules that cause cells to cause asthma---a finding that paves the way for developing more effective drugs for treatment. (1998-12-17)

Dynavax Demonstrates Ability Of Immunostimulatory DNA Sequences To Inhibit Symptoms Of Allergic Asthma In Animal Model
Injections of immunostimulatory DNA sequences developed by Dynavax Technologies inhibited disease symptoms as effectively as seven days of systemic corticosteroids in an animal model of asthma. Moreover, unlike the corticosteroids, ISS-DNA injections redirected the immune response away from the Th2 response associated with allergic inflammation toward a non-allergic Th1 response. (1998-12-15)

Immunity's Nervous Supervisor
As reported in PNAS, direct communication between the nervous and immune systems, discovered by Weizmann Institute scientists, may help understand and eventually treat autoimmune disorders. (1998-11-30)

New Hypothesis Proposed For Cause Of Chronic Fatigue Syndrome
Researchers propose a new theory for the cause of chronic fatigue syndrome (CFS) -- one that blames the illness on a low-level viral infection and on the body's own immune response. If true, it would offer an explanation for why virologists so far haven't found evidence of a common virus. (1998-10-29)

Fred Hutchinson Cancer Research Center And Targeted Genetics Announces Issuance Of Braod Patent Covering Antigen-Specific T Cell Expansion
Fred Hutchinson Cancer Research Center and Targeted Genetics Corporation (Nasdaq: TGEN) announce that they have received notification from the U.S. Patent and Trademark Office regarding the issuance of patent #5,827,642 entitled (1998-10-27)

Study Ties Cerebral Palsy To Inflammation And Blood-Clotting Abnormalities
Groundbreaking new research provides strong evidence that inflammation and clotting abnormalities may be important causes of cerebral palsy (CP) in full-term babies, who account for about half of all children with this disorder. The study may lead to ways of identifying babies at risk for CP and ultimately to new therapies that might prevent brain damage in some children. (1998-10-01)

Gene Therapy Showing Promise In Fighting Melanoma
In treating dogs for a highly aggressive form of melanoma, a University of Wisconsin-Madison research team is having success with a new cancer vaccine that could benefit human cancer-fighting efforts. (1998-09-03)

A Common Microbe Could Help To Trigger Alzheimers
A common microbe, Chlamydia pneumoniae, could trigger Alzheimer's disease, say researchers in the US. If true, scientists will have to find out if the disease could be prevented by a simple course of antibiotics. (1998-08-12)

The Perils Of Discontinuing Therapy: Without HAART, Cytokines Stimulate HIV From Latently Infected Cells
When an HIV-infected patient discontinues highly active antiretroviral therapy (HAART), the virus almost invariably rebounds to substantial levels, even if virus had become undetectable by standard tests because of therapy. New findings from NIAID provide an explanation. (1998-07-06)

Fauci To Present New Insights Into HIV Latency At 12th World AIDS Conference
New data show that latent pools of infected cells are established very early in the course of HIV infection, even if a patient is treated expeditiously with highly active antiretroviral therapy. Anthony S. Fauci, M.D., NIAID director, will present these and other new findings at the 12th World AIDS Conference in Geneva, Switzerland. (1998-06-30)

Old Drugs, New Tricks
Work from the team headed by Bart Staels (INSERM 325, directed by Professor Jean-Charles Fruchart), published in the June 25, 1998 edition of Nature, suggests that fibrates, a class of lipid-lowering drugs, have a vascular anti- inflammatory action. Fibrates might therefore have a beneficial vascular effect in atherosclerosis and restenosis. (1998-06-24)

Researchers Identify New Mechanism Underlying Pain
New research on neuropathic pain -- the kind of burning, shooting pain for which standard analgesics provide little relief -- is producing evidence that the immune system is intimately involved in the initiation and maintenance of pain, through production of proteins called cytokines. (1998-02-13)

Fauci: New Findings Help Explain "Rebound" Of HIV In Patients Who Discontinue Triple-Drug Therapy
Researchers at the National Institute of Allergy and Infectious Diseases (NIAID) have helped answer an important question in the treatment of HIV-infected individuals: why, in patients receiving aggressive antiretroviral therapy who have no easily detectable HIV in their blood, does the virus rapidly rebound to high levels if the drugs are discontinued? (1998-02-02)

Two-Pronged Attack On Immune System Cells Engineered By HIV Gene vpr: Effects Markedly Reversed By Antisteroid Compound RU-486
The HIV gene vpr blocks cytokine production in the first- infected cells, macrophages, blunting the immune response, and prevents apoptosis in the cells, preserving them as viral production factories. In a further blow to the immune system, vpr induces apoptosis in neighboring T cells that have not yet been infected. (1997-10-01)

Role Of Cytokines In Treating Heart Disease Unveiled By Penn Scientists
University of Pennsylvania Medical Center researchers are investigating the role of cytokines in explaining the effectiveness of amlodipine, a widely prescribed calcium- channel blocker for patients with heart failure. A better understanding of the relationship between cytokines and amlodipine is hoped to lead to more effective therapies for heart failure. (1997-08-26)

Mother's Milk: Nutrition And Nurture For Infants -- And The Best Defense Against Disease
Breast-fed babies experience fewer and less serious incidences of disease and allergy than formula-fed babies. Gastrointestinal, respiratory, and middle-ear infections, in particular, are greatly reduced in breast-fed infants. In recent years, scientists have begun to explore what makes breast milk so protective for infants. (1997-07-31)

Emory Researchers Advance Gene Therapy Studies For Metastatic Melanoma Treatment
Melanoma reseachers at Emory University are uncovering new information about a vital cellular ingredient which they believe may direct the body's immune system to kill malignant melanoma tumor cells. (1997-04-24)

National Jewish Medical And Research Center Shows Rush Immunotherapy Results In Allergen-Specific Changes In T Cells
National Jewish Medical and Research Center shows rush immunotherapy results in allergen-specific changes in T cells (1997-04-21)

Herpes-Based Gene Therapy Is Key To Promising Liver Tumor Vaccine
Physicians from Memorial Sloan-Kettering Cancer Center and the University of Rochester's Cancer Center have created a promising compound that recruits the body's immune system to target and wipe out cancer cells in the liver. In a study with laboratory rats, the majority of animals injected with the vaccine were cancer-free, while similar animals that did not receive the vaccine typically had dozens of tumors. (1997-04-07)

Herpes-Based Gene Therapy Is Key To Promising Liver Tumor Vaccine
Physicians from the University of Rochester's Cancer Center and Memorial Sloan-Kettering Cancer Center have created a promising compound that recruits the body's immune system to target and wipe out cancer cells in the liver. The majority of rats injected with the vaccine were cancer-free, while control animals typically had dozens of tumors (1997-04-03)

Hormones Focus Of Study On How Responses To Infection Are Regulated
University of Illinois scientists are studying how behavioral responses to infection are focusing on glucocorticoids - naturally occurring hormones. (1997-03-13)

Fauci: New Findings On Host Factors Illuminate AIDS Pathogenesis
A clearer picture is now emerging of how factors intrinsic to the HIV-infected individual influence the rate at which HIV replicates in the person's body and how rapidly the patient will develop AIDS, says Anthony S. Fauci, M.D., director of the National Institute of Allergy and Infectious Diseases (NIAID). (1996-12-12)

Brain Cancer Vaccine Boosts Immune System To Kill Tumor Cells
A cancer vaccine developed by Duke University Comprehensive Cancer Center researchers is showing promise in mice of treating brain tumors that had been thought (1996-09-17)

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