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Disproportionate effects of COVID-19 on socially vulnerable communities
Authors found that COVID-19 has disproportionately affected socially vulnerable communities, especially minority and non-English speaking ones. (2020-06-25)

Study finds depression associated with greater risk of cardiovascular disease
A new study co-led by Simon Fraser University health sciences professor Scott Lear provides further evidence of the link between depressive symptoms and an increased risk of heart disease and early death. (2020-06-15)

Women are not more likely to die of cirrhosis than men, despite fewer liver transplants
Prior studies suggested women might have higher mortality of cirrhosis of the liver than men. Women are also less likely to receive liver transplantation. But the research was unclear. A comprehensive new Northwestern Medicine study shows women are not more likely to die of liver cirrhosis than men, demonstrating that this liver disease affects men and women similarly. (2020-06-04)

Glucocorticoids are harmful in treating viral respiratory infections
Glucocorticoids, which are widely used as treatment in intensive care, can nearly quadruple the death rate of patients suffering from acute respiratory distress syndrome. Researchers at the University of Turku, Finland, discovered the reason for the higher mortality. The findings are also important in the fight against COVID-19 disease. (2020-05-29)

First study of COVID-19 patients with diabetes shows that 10% die within seven days of hospital admission
The first study of COVID-19 to specifically analyse the effect of the disease in hospitalised patients with diabetes has found that one in ten patients dies within 7 days of hospital admission, and one in five is intubated and mechanically ventilated by this point. The research is published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]). (2020-05-28)

Bullying is common factor in LGBTQ youth suicides, YSPH study finds
Researchers at the Yale School of Public Health have found that death records of LGBTQ youth who died by suicide were substantially more likely to mention bullying as a factor than their non-LGBTQ peers. (2020-05-27)

Bullying is common factor in LGBTQ youth suicides, Yale study finds
Researchers at the Yale School of Public Health have found that death records of LGBTQ youth who died by suicide were substantially more likely to mention bullying as a factor than their non-LGBTQ peers. The researchers reviewed nearly 10,000 death records of youth ages 10 to 19 who died by suicide in the United States from 2003 to 2017. (2020-05-26)

Walking or cycling to work associated with reduced risk of early death and illness
People who walk, cycle and travel by train to work are at reduced risk of early death or illness compared with those who commute by car. (2020-05-19)

'Cells-soldiers' turned to be more resistant than 'cells-combat medics'
Researchers from Sechenov University (Russia) and University of Pittsburgh (USA) discovered that the resistance of innate immune cells, macrophages, to ferroptosis -- a type of programmed cell death -- depends on the type of their activation. It turned out that cells helping tissues to recover from inflammation were more vulnerable. The researchers identified the mechanisms underlying the cells' resistance and explained how this research would help regulate inflammation in a paper published in Nature Chemical Biology. (2020-05-16)

High calcium levels in mitochondria linked to neuronal death in Alzheimer's disease
For the first time, using a mouse model of Alzheimer's disease, scientists at Massachusetts General Hospital have documented a link between raised levels of calcium in mitochondria and neuronal death in the living brain. (2020-05-12)

Stem cells shown to delay their own death to aid healing
A new study shows how stem cells -- which can contribute to creating many parts of the body, not just one organ or body part -- are able to postpone their own death in order to respond to an injury that needs their attention. The study was done in planarians, which are tiny worms used as model organisms to study regeneration because of their ability to recover from any injury using stem cells. (2020-05-07)

A new way to accurately estimate COVID-19 death toll
A Rutgers engineer has created a mathematical model that accurately estimates the death toll linked to the COVID-19 pandemic in the United States and could be used around the world. (2020-04-30)

Some worms programmed to die early for sake of colony
Some worms are genetically predisposed to die before reaching old age, which appears to benefit the colony by reducing food demand, finds a new UCL-led study published in Aging Cell. (2020-04-16)

Discovering the secrets of the enigmatic caspase-6
Researchers identified the mechanisms underlying the innate immune function of the enzyme caspase-6, offering ways to combat viral infection, inflammatory diseases and cancer. (2020-04-15)

Celiac disease linked to increased risk of premature death
People with celiac disease have increased risk of dying prematurely, despite increased awareness of the disease in recent years and better access to gluten-free food. This is according to a new study from Karolinska Institutet in Sweden and Columbia University in the US published in the prestigious journal JAMA. Celiac disease was linked to increased risk of death from cardiovascular disease, cancer and respiratory disease. (2020-04-07)

Cancer research, the guardian of the genome has a new ally
They identified a protein that, like a switch, controls the onset of cell death processes in cancer cells, which are regulated by p53, the protein known as 'the guardian of the genome.' The findings will be used to develop more tailored and effective cancer treatments. (2020-03-31)

Risk of death from stroke falls by 24%
Thousands more patients each year are surviving strokes, as the risk of death and disability after a stroke fell significantly between 2000 and 2015, according to analysis by Guy's and St Thomas' researchers. (2020-03-30)

Healthy lifestyle reduces risk of disease, death
The longer you lead a healthy lifestyle during midlife, the less likely you are to develop certain diseases in later life. (2020-03-11)

Inherited arrhythmia in young Finnish Leonbergers under investigation
Inherited malignant ventricular arrhythmia is a fairly common disorder among Finnish Leonbergers under three years of age, with the most severe cases potentially resulting in sudden death. Researchers are striving to identify the gene mutation underlying the disorder. (2020-03-10)

Hospices struggle to deliver specialized support to children when a parent is dying
Support available to children experiencing the death of a parent varies across the country, new research published in the BMJ Supportive & Palliative Care finds. (2020-03-09)

Why Edgar Allan Poe probably did not kill himself
A computational analysis of language used by the writer Edgar Allan Poe has revealed that his mysterious death was unlikely to have been suicide. The author, poet, and literary critic died in 1849 after spending several days in hospital while in a state of delirium. To date, Poe's death remains an unsolved enigma, with his contemporary, poet Charles Baudelaire even speculating that the incident was 'almost a suicide, a suicide prepared for a long time.' (2020-02-24)

Want to live longer? Stay in school, study suggests
A multi-institution study led by the Yale School of Medicine and University of Alabama-Birmingham has attempted to tease out the relative impact of two variables most often linked to life expectancy -- race and education -- by combing through data about 5,114 black and white individuals in four US cities. (2020-02-20)

Dementia may reduce likelihood of a 'good death' for patients with cancer
As the population ages, the number of cancer patients with dementia has increased. A recent study published in Geriatrics & Gerontology International found that cancer patients with dementia were less likely to achieve a 'good death' than those without. (2020-02-05)

Solitary confinement significantly increases post-prison death risk
Even just a few days of solitary confinement may significantly increase inmates' risk of death after serving their sentences. (2020-02-05)

Homicide is a leading cause of pregnancy-associated death in Louisiana
Homicide is a leading cause of death among pregnant and postpartum women in Louisiana, according to an analysis of birth and death records from 2016 and 2017. The study, appearing as a research letter in JAMA Pediatrics, was funded by the Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), part of the National Institutes of Health. (2020-02-03)

Birth timing may affect brain development
Moving birth a day early triggers an early start to widespread neuron death, according to new research in mice published in eNeuro. (2020-02-03)

People with inadequate access to food 10% to 37% more likely to die prematurely
Adults with food insecurity (i.e., inadequate access to food because of financial constraints) are 10% to 37% more likely to die prematurely from any cause other than cancer compared to food-secure people, found new research in CMAJ. (2020-01-20)

Sperm donation to strangers after death should be allowed in the UK, say ethicists
Men in the UK should be allowed to voluntarily donate their sperm after death, if they want to, argue ethicists in an analysis published online in the Journal of Medical Ethics. (2020-01-20)

Death rates plunge in older people with diabetes, but not younger people
New research covering the entire population of Hong Kong shows that while death rates from any cause (all-cause mortality), cardiovascular disease and cancer are plummeting overall and in adults with diabetes aged 45 to 74 years, those in younger adults aged 20 to 44 years are barely changing. (2020-01-16)

Hospital readmission policy did not increase patients' mortality risk
The Obamacare program intended to reduce the risk of patients being readmitted after hospitalizations for heart attacks, heart failure, and pneumonia has not caused an increase in mortality risk for patients in emergency departments or observational units, according to a new report. (2020-01-15)

Lower levels of lymphocyte blood cells may indicate increased risk of death
Lower levels of lymphocyte blood cells -- a condition called lymphopenia -- could be an early warning for future illness, as low counts were associated with a 60% increase in death from any cause, found a Danish study in CMAJ (Canadian Medical Association Journal). (2020-01-13)

Scientists find a new use for already known anti-cancer drugs
The world scientific community is waging a difficult and prolonged war on cancer. New research in the field of immunogenic cell death can extend the area of drugs application and ensure patients' protection from relapse after therapy. Cancer treatment is not just the removal of the tumor cells from the body, and chemotherapy. The doctors' aim is to provide a scenario that would prevent tumor cells from proliferating and causing a new disease. (2020-01-03)

Bacteria can 'outsmart' programmed cell death
To be able to multiply, bacteria that cause diarrhoea block mediators of programmed cell death, a new study in 'Nature Microbiology' shows. (2019-12-24)

Breaking the dogma: Key cell death regulator has more than one way to get the job done
Immunologists from St. Jude Children's Research Hospital have revealed two independent mechanisms driving self-defense molecules to trigger cell death. (2019-12-23)

Time-to-death of Roman emperors followed distinct pattern
Roman emperors faced a high risk of violent death in their first year of rule, but the risk slowly declined over the next seven years, according to an article published in the open access journal Palgrave Communications. When statistically modelled, the length of time from the beginning of their reign until their death followed a set pattern, similar to that seen in reliability engineering, interdisciplinary research by Dr. Joseph Saleh, an Aerospace Engineer from the Georgia Institute of Technology, US suggests. (2019-12-22)

Email users should have 'more control' over post-mortem message transmission
Email users should have far more control over the transmission of their messages upon death, a new Aston Business School study suggests. (2019-12-18)

Australian and US team discover new human autoinflammatory disease
Scientists from Australia and the US have discovered and identified the genetic cause of a previously unknown human autoinflammatory disease. The researchers determined that the autoinflammatory disease, which they termed CRIA (cleavage-resistant RIPK1-induced autoinflammatory) syndrome, is caused by a mutation in a critical cell death component called RIPK1. The discovery suggests that compounds that inhibit cell death might be useful in treating autoinflammatory diseases. (2019-12-11)

Insights into a versatile molecular death switch
The enzyme caspase-8 regulates different modes of cell death, a publication by Hamid Kashkar in 'Nature' shows. (2019-11-26)

Doctors should avoid co-prescribing benzodiazepines to opioid dependent patients
Doctors should avoid co-prescribing benzodiazepines to opioid dependent patients who are being treated with methadone or buprenorphine, also known as opioid agonist treatment (OAT), due to a three-fold increase in risk of overdose death, according to a study led by researchers at the University of Bristol. (2019-11-26)

Cells control their dance of death
La Trobe University researchers have revealed for the first time how white blood cells control the final moments of their death, helping their own removal from the human body. (2019-11-12)

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