Current Diabetes News and Events

Current Diabetes News and Events, Diabetes News Articles.
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Timing of physical activity linked to fitness levels, CV risk for men with type 2 diabetes
Research published in Diabetes Care by Brigham and Women's Hospital and Joslin Diabetes Center investigators, along with collaborators, reports a correlation between the timing of moderate-to-vigorous physical activity and cardiovascular fitness and health risks for individuals who have type 2 diabetes and obesity or overweight. (2021-02-17)

New data on COVID-19 patients with diabetes show that one in five die within
Updated results from the CORONADO study, analysing the outcomes of patients with diabetes admitted to hospital with COVID-19, shows that one in five patients die within 28 days while around half are discharged. The study is published in Diabetologia (the journal of the European Association for the Study of Diabetes [EASD]). (2021-02-17)

IU researchers find disease-related gene changes in kidney tissue
Researchers from Indiana University have identified key genetic changes in the interstitial kidney tissue of people with diabetes, a discovery that signifies the potential for a revolutionary new genetic approach to the treatment of kidney disease. They will contribute their findings to the Kidney Precision Medicine Project's (KPMP) ''cell atlas,'' a set of maps used to classify and locate different cell types and structures within the kidney. (2021-02-16)

Prediabetes may be linked to worse brain health
For the study, published in the journal Diabetes, Obesity and Metabolism, researchers analysed data from the UK Biobank of 500,000 people aged 58 years on average, and found that people with higher than normal blood sugar levels were 42% more likely to experience cognitive decline over an average of four years, and were 54% more likely to develop vascular dementia over an average of eight years (although absolute rates of both cognitive decline and dementia were low). (2021-02-11)

Study: Diabetes complications in young children target the brain
Brain volume, verbal IQ, and overall IQ are lower in children with Type 1 diabetes (T1D) than in children without diabetes, according to a new longitudinal study published in Diabetes Care, a journal of the American Diabetes Association. The nearly eight-year study compared brain scans of young children who have T1D with those of non-diabetic children to assess the extent to which glycemic exposure may adversely affect the developing brain. (2021-02-10)

New targets for the development of a drug treatment for obesity and type 2 diabetes
The GIP receptor in the central nervous system plays a crucial role in the regulation of body weight and food intake. This is shown by a recent study by Helmholtz Zentrum München, ETH Zurich and the German Center for Diabetes Research (DZD). The study, which has now been published in 'Cell Metabolism', identifies new targets for the development of a drug treatment for obesity and type 2 diabetes. (2021-02-10)

Type 2 diabetes: drugs initially increase glucose production
Although SGLT-2 inhibitors are central to the treatment of diabetes, their exact mode of action was hitherto unknown. A study shows that there is a direct correlation between the elimination of glucose via the kidneys and new glucose production in the liver. (2021-02-08)

Immune response to insulin could identify, help treat those at risk for Type 1 Diabetes
Researchers from the Barbara Davis Center for Childhood Diabetes at the University of Colorado Anschutz Medical Campus have found that immune responses to insulin could help identify individuals most at risk for developing Type 1 diabetes. (2021-02-08)

"Prediabetes" diagnosis less useful in older patients
Older adults who are classified as having ''prediabetes'' due to moderately elevated measures of blood sugar usually don't go on to develop full-blown diabetes. (2021-02-08)

Higher excess COVID-19 death risk in middle-aged people with type 2 diabetes
A largescale analysis led by the University of Exeter and funded by Diabetes UK, has found a disproportionately higher COVID-19 death risk in middle-aged people with type 2 diabetes, raising questions over vaccination strategies across Europe. (2021-02-08)

Cancer leading cause of death among people with diabetes
Cancer is the leading cause of death among people with diabetes in England. (2021-02-04)

New guidance on how cardiac patients with diabetes can exercise more safely
Cardiac patients who also have diabetes will be able to do their rehabilitation exercises more safely, thanks to the world's first guidance on the subject, which has been published by international experts including a Swansea University academic. The guidance will be a crucial resource for healthcare professionals, so they can help the growing number of cardiac rehabilitation patients who also have diabetes. (2021-02-04)

Extreme blood sugar swings in people with type 2 diabetes may increase heart disease risk
In patients with type 2 diabetes, big swings in blood sugar levels between doctors' visits are associated with an increased risk of heart disease. (2021-02-03)

Insulin can be stored out of refrigeration in hot settings!
Patients with diabetes must keep a supply of insulin which must respect the cold chain. However not every household has a refrigerator. This forces people living with diabetes to go to hospital on a daily basis. MSF and UNIGE test insulin storage at temperatures ranging from 25°C to 37°C. The findings demonstrate that the stability of insulin stored under these conditions is the same as that of cold-stored insulin, with no impact on efficacy. (2021-02-03)

Diabetes during pregnancy may increase risk of heart disease
An analysis of more than 1,000 women found that a history of gestational diabetes (diabetes during pregnancy) doubled the risk of heart artery calcification - a marker of increased risk for heart disease - many years after pregnancy, at the average age of 48, even if blood sugar returned to healthy levels. (2021-02-01)

Social media study reveals diabetics' fear of disrupted insulin supplies because of Brexit
Diabetics living in the UK worry about disruption to insulin supplies as a result of Brexit, new research shows. (2021-01-27)

Scientists discover a new promising target for diabetes treatment
Researchers have discovered a novel and druggable insulin inhibitory receptor, named inceptor. The blocking of inceptor function leads to an increased sensitisation of the insulin signaling pathway in pancreatic beta cells. This might allow protection and regeneration of beta cells for diabetes remission. (2021-01-27)

Addressing health disparities in diabetes requires a broader look at systemic racism
Poor social conditions caused by systemic racism contribute to health disparities in people with diabetes, according to a paper published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2021-01-26)

Hybrid closed-loop insulin therapy improves glycemic control
Hybrid closed-loop insulin therapy improved glycemic control in adolescents and young adults with type 1 diabetes. These outcomes, derived from the International Diabetes Closed-Loop (iDCL) (2021-01-26)

Mouse study identifies novel compound that may help develop diabetes drugs
Research led by The Ohio State University Wexner Medical Center and College of Medicine identified a new compound that might serve as a basis for developing a new class of drugs for diabetes. Study findings are published online in the journal Nature Chemical Biology. (2021-01-26)

Placental function can illuminate future disease in adults and children
Researchers at the University of Colorado Anschutz Medical Campus have discovered a direct association between placental function in pregnant women and future metabolic disorders in children and adults, a finding that could lead to earlier intervention and diagnosis of disease. (2021-01-22)

Addressing the impact of structural racism on disparities in children with Type 1 diabetes
Advancements in diabetes technology have improved quality of life and glycemic control in children with type 1 diabetes. However, data show that a subset of children is being left behind. Those from low-income families and non-Hispanic Black (NHB) children are not experiencing benefits associated with technological advances, and are at higher risk for diabetes complications and adverse outcomes through ongoing poor glycemic control. (2021-01-22)

The interconnection of global pandemics -- Obesity, impaired metabolic health and COVID-19
In a Nature Reviews Endocrinology article authors from the German Center for Diabetes Research (DZD) highlight the interconnection of #obesity and impaired metabolic health with the severity of #COVID19. #diabetes (2021-01-21)

Gastrointestinal surgery can be a cure for type 2 diabetes finds new long-term study
The results of a randomised clinical trial with the longest follow up to date show that metabolic surgery is more effective than medications and lifestyle interventions in the long-term control of severe type 2 diabetes. (2021-01-21)

Type 2 Diabetes: New Evidence Underlines the Role of Obesity in Late Complications
Successful weight loss is considered to be an integral part of the therapy for type 2 diabetes. New data from a large-scale observational study carried out at German Institute of Human Nutrition in cooperation with the German Center for Diabetes Research support the current recommendations of physicians. The findings, published in the journal Diabetologia, suggest that obesity and weight gain can lead to vascular disorders, the leading cause of disease and death for people with type 2 diabetes. (2021-01-20)

Altering mealtimes could prevent development of Type 2 diabetes
An innovative new study is set to examine if changing our mealtimes to earlier or later in the day could reduce the risk of developing Type 2 diabetes. (2021-01-15)

Metformin use reduces risk of death for patients with COVID-19 and diabetes
Use of the diabetes drug metformin -- before a diagnosis of COVID-19 -- is associated with a threefold decrease in mortality in COVID-19 patients with Type 2 diabetes, according to a racially diverse study at the University of Alabama at Birmingham. Diabetes is a significant comorbidity for COVID-19. This beneficial effect remained, even after correcting for age, sex, race, obesity, and hypertension or chronic kidney disease and heart failure. (2021-01-14)

ADA lowers target HbA1C levels for children with type-1 diabetes
In early 2020, upon recommendation by leading endocrinologists, American Diabetes Association lowered the target hemoglobin A1C guidelines for children with type 1 diabetes. Their goal in recommending stricter glucose control was to ensure children with type 1 diabetes have better immediate and long-term health outcomes with fewer health complications and reduced mortality rates. In this ''Perspective'' article they discuss the evidence and rationale behind this new recommendation. (2021-01-14)

Short term low carbohydrate diet linked to remission of type 2 diabetes
Patients with type 2 diabetes who follow a strict low carbohydrate diet for six months may experience greater rates of remission compared with other recommended diets without adverse effects, suggests a study published by The BMJ today. (2021-01-13)

Research finds increased first-trimester exercise may reduce gestational diabetes risk
Pregnant women who exercise more during the first trimester of pregnancy may have a lower risk of developing gestational diabetes, according to a new study led by Samantha Ehrlich, an assistant professor in the Department of Public Health at the University of Tennessee, Knoxville. The analysis found that lower risk was associated with at least 38 minutes of moderate intensity exercise each day--more than current recommendations of at least 30 minutes a day five days a week. (2021-01-11)

Black people with type 1 diabetes, COVID-19 are four times more likely to be hospitalized for diabetic ketoacidosis
Black and Hispanic people with COVID-19 and diabetes are more likely than Caucasians to die or have serious complications, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2021-01-07)

Routine eye scans may give clues to cognitive decline in diabetes
As they age, people with diabetes are more likely to develop Alzheimer's disease and other cognitive disorders than are people without diabetes. Scientists at Joslin Diabetes Center now have shown that routine eye imaging can identify changes in the retina that may be associated with cognitive disorders in older people with type 1 diabetes. These results may open up a relatively easy method for early detection of cognitive decline in this population. (2021-01-05)

Common diabetes drug may trigger rare complications for COVID-19 patients
An uptick in a particular type of DKA called euDKA at Brigham and Women's Hospital during the COVID-19 pandemic has led researchers to hypothesize that diabetes patients on glucose-lowering drugs may be at increased risk for euDKA when they contract COVID-19. The observational case series was published in The American Association of Clinical Endocrinologists Clinical Case Reports. (2020-12-24)

New research highlights the importance of a forgotten organ in ensuring healthy pregnancies
An international research team led by UBC has uncovered for the first time the importance of a small gland tucked behind the sternum that works to prevent miscarriage and diabetes in pregnant women. (2020-12-23)

The thymus as key to healthy pregnancies
How the immune system adapts to pregnancy has puzzled researchers for decades. An international team of researchers, including scientists from IMBA (Institute of Molecular Biotechnology) of the Austrian Academy of Sciences has now discovered that important changes in the thymus occur in order to prevent miscarriages and gestational diabetes. The results are published in the journal Nature. (2020-12-23)

Artificial intelligence predicts gestational diabetes in Chinese women
Machine learning, a form of artificial intelligence, can predict which women are at high risk of developing gestational diabetes and lead to earlier intervention, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2020-12-22)

Lipid identified in human breast milk may play important role in early childhood weight
A lipid metabolite called 12,13-diHOME is in human breast milk. The authors of the study propose that 12,13-diHOME, as well as linked pathway metabolites from breast milk, have a protective effect against obesity development in offspring. They also suggest that a single bout of maternal exercise may boost levels of the metabolite in breast milk and that may translate into benefits for offspring in terms of healthy growth and development. (2020-12-16)

CAN risk in diabetes reduced with intensive control of blood glucose and blood pressure
Cardiovascular autonomic neuropathy (CAN), a frequent but underdiagnosed complication of diabetes that can be life-threatening. Researchers found that intensive glycemic control reduced CAN risk by 17%, while intensive blood pressure control reduced risks by 22%. (2020-12-16)

Water may be an effective treatment for metabolic syndrome
Researchers at the University of Colorado Anschutz Medical Campus have discovered that fructose stimulates the release of vasopressin, a hormone linked to obesity and diabetes. They also found that water can suppress the hormone and alleviate these conditions in mice. (2020-12-15)

Diabetes in dogs may indicate elevated risk of type 2 diabetes in their owners
Owners of a dog with diabetes are more likely to develop type 2 diabetes than owners of a dog without diabetes. No shared risk of diabetes could be detected for cat owners and their cats. These novel findings, from a register-based study conducted at Uppsala University in collaboration with three other universities, have now been published in The BMJ. (2020-12-10)

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