Current Diabetic Retinopathy News and Events

Current Diabetic Retinopathy News and Events, Diabetic Retinopathy News Articles.
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New therapeutic approach may help treat age-related macular degeneration effectively
Runt-related transcription factor 1 (RUNX1) has been linked to retinal neovascularization and the development of abnormal blood vessels, which result in vision loss in diabetic retinopathy. Now, scientists have found that RUNX1 inhibition presents a new therapeutic approach in the treatment of age-related macular degeneration (AMD), which is the leading cause of blindness in the elderly worldwide. Their results are reported in The American Journal of Pathology, published by Elsevier. (2021-02-22)

New discovery could pave the way for improved treatments for diabetes
Monash University researchers have uncovered the barrier to β-cell (beta cell) regeneration that could pave the way for improved treatments for diabetes and diseases that involve organ and tissue damage. (2021-02-12)

Monitoring the body's fat burning by breath
Your breath holds the key to monitoring fat burning, and now a research group from Tohoku University has created a compact and low-cost device that can measure how our body metabolizes fat. (2021-02-10)

Synthesized very-long-chain polyunsaturated fatty acids improved retinal function in mice
A University of Utah ophthalmologist is investigating how lipids known as VLC-PUFAs could be used to prevent eye disease thanks to a new way to synthesize them for research. (2021-02-04)

Halved risk for severe retinal disease in extremely premature infants
Risk for a severe form of retinopathy of prematurity, which can cause blindness in extremely premature babies, was halved when the newborns were given a new supplement combining various fatty acids. This was shown in a Swedish study led from the University of Gothenburg. (2021-02-01)

Social media study reveals diabetics' fear of disrupted insulin supplies because of Brexit
Diabetics living in the UK worry about disruption to insulin supplies as a result of Brexit, new research shows. (2021-01-27)

ADA lowers target HbA1C levels for children with type-1 diabetes
In early 2020, upon recommendation by leading endocrinologists, American Diabetes Association lowered the target hemoglobin A1C guidelines for children with type 1 diabetes. Their goal in recommending stricter glucose control was to ensure children with type 1 diabetes have better immediate and long-term health outcomes with fewer health complications and reduced mortality rates. In this ''Perspective'' article they discuss the evidence and rationale behind this new recommendation. (2021-01-14)

Black people with type 1 diabetes, COVID-19 are four times more likely to be hospitalized for diabetic ketoacidosis
Black and Hispanic people with COVID-19 and diabetes are more likely than Caucasians to die or have serious complications, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2021-01-07)

Routine eye scans may give clues to cognitive decline in diabetes
As they age, people with diabetes are more likely to develop Alzheimer's disease and other cognitive disorders than are people without diabetes. Scientists at Joslin Diabetes Center now have shown that routine eye imaging can identify changes in the retina that may be associated with cognitive disorders in older people with type 1 diabetes. These results may open up a relatively easy method for early detection of cognitive decline in this population. (2021-01-05)

AI algorithms detect diabetic eye disease inconsistently
In a paper published Jan. 5 in Diabetes Care, researchers compared seven algorithms to detect diabetic retinopathy against the diagnostic expertise of retina specialists. (2021-01-05)

Common diabetes drug may trigger rare complications for COVID-19 patients
An uptick in a particular type of DKA called euDKA at Brigham and Women's Hospital during the COVID-19 pandemic has led researchers to hypothesize that diabetes patients on glucose-lowering drugs may be at increased risk for euDKA when they contract COVID-19. The observational case series was published in The American Association of Clinical Endocrinologists Clinical Case Reports. (2020-12-24)

Surgical and drug treatment options lead to similar outcomes for diabetic eye disease
Surgical and injectable drug approaches are equally effective for treatment of bleeding inside the eye from proliferative diabetic retinopathy (PDR), according to a National Eye Institute (NEI)-supported clinical study from the DRCR Retina Network (DRCR.net). (2020-12-15)

Study connects diabetes, air pollution to interstitial lung disease
People with pre-diabetes or diabetes who live in ozone-polluted areas may have an increased risk for an irreversible disease with a high mortality rate. These findings are especially important today in the midst of the COVID-19 pandemic, where there is a heightened concern for the convergence of health effects from air pollution and SARS-CoV-2 in susceptible populations. (2020-12-09)

The gut microbiome in polycystic ovary syndrome and its association with metabolic traits
University of Tartu researchers and their collaborators from Finland and Spain investigated the relationship between the gut microbiome and polycystic ovary syndrome. Their study revealed that women with polycystic ovary syndrome in their late reproductive years have significant microbial changes in gut-related to their metabolic health. (2020-12-08)

Researchers say we're watching the world go blind
Three University of Michigan researchers say eye care accessibility around the globe isn't keeping up with an aging population, posing challenges for eye care professionals over the next 30 years. (2020-12-07)

Researchers use genomics to identify diabetic retinopathy factors
In the paper, ''Integration of genomics and transcriptomics predicts diabetic retinopathy susceptibility genes,'' published in eLife, researchers identified genes that respond differently in response to high glucose in individuals with and without diabetic retinopathy. (2020-12-07)

Kidney injury in diabetic ketoacidosis linked to brain injury
Researchers have identified factors that make children with diabetic ketoacidosis more likely to experience acute kidney injury. Analyzing data from a large, multicenter clinical trial, the researchers also found that children who experience acute kidney injury are more likely to also experience subtle cognitive impairment and demonstrate lower IQ scores, suggesting a pattern of multiple organ injury. (2020-12-04)

Targets for avoidable sight loss 'not being met': 30-year study finds
A new global study has found no significant reduction in the number of people with treatable sight loss since 2010. (2020-12-01)

Signaling switch in pancreatic β-cells determines anti-diabetic drug effectiveness
An international research group headed by Professor SEINO Susumu (Kobe University Graduate School of Medicine) has clarified the action mechanism of widely utilized incretin-based drugs in the treatment of diabetes. These findings are important for illuminating the mechanism behind diabetes and will hopefully provide a basis for new treatments. (2020-11-25)

High blood sugar could increase COVID-19 death risk for non-diabetics, says study
Abnormally high blood sugar may worsen outcomes and mortality rates for COVID-19 patients, including those without diabetes, according to major research published in the peer-reviewed open access journal Annals of Medicine. (2020-11-23)

Diabetic eye disease associated with five-fold risk of severe COVID-19
People with diabetes and eye disease have a five-fold increased risk of requiring intubation when hospitalised with COVID-19. (2020-11-23)

Incretin hormone levels linked to arteriosclerosis
Diabetes is currently treated using incretin hormones to reduce the risk of cardiovascular disease and other medical issues that the illness can trigger. Now researchers from Lund University in Sweden have noted new links between these hormones and arteriosclerosis, and believe their discovery could be significant for treatment of diabetes in the future. The study is published in Diabetes Care. (2020-11-19)

Diabetes increases neuritic damage around amyloid plaques in Alzheimer's disease
New research from the University of Eastern Finland explores the role of diabetes in the cellular and molecular changes underlying Alzheimer's disease (AD). (2020-11-18)

An acebuchin-oil-enriched diet helps to reduce hypertension
The acebuche, also know as the wild olive tree, is a variety of tree widely found throughout Spain and covering almost nine million hectares in Andalusia. However, little data is available on the composition and therapeutic potential of acebuchin oil. The studies mainly focus on the composition and pharmacological effects of olive tree leaves and extra virgin olive oil. (2020-11-17)

Scientists discover secret to superbug's virulence in diabetic infections
The bodies of people with uncontrolled diabetes appear to be the perfect environment for a common type of superbug to thrive unchecked and do its worst damage, according to new research reported today in Science Advances. Staphylococcus aureus -- a bacteria that is often resistant to antibiotics -- thrives in glucose-rich diabetic conditions, which trigger it to activate some of its most virulent features. A lack of insulin prevents the immune system from responding to the infection. (2020-11-13)

Diabetes drug can treat and reverse heart failure and reduce
Mount Sinai clinical trial results could help lead to FDA approval (2020-11-13)

Novel deep learning method enables clinic-ready automated screening for diabetes-related eye disease
Researchers at Helmholtz Zentrum München together with LMU University Eye Hospital Munich and the Technical University of Munich (TUM) created a novel deep learning method that makes automated screenings for eye diseases such as diabetic retinopathy more efficient. (2020-11-12)

Chemicals in your living room cause diabetes
A new UC Riverside study shows flame retardants found in nearly every American home cause mice to give birth to offspring that become diabetic. (2020-11-10)

Diabetes epidemic detected among Xavante indigenous community in Central Brazil
Researchers examine retinas and find high prevalence of type 2 diabetes as well as ocular problems caused by the disease. (2020-11-10)

New strategy for treating common retinal diseases shows promise
Scientists at Scripps Research have uncovered a potential new strategy for treating eye diseases that affect millions of people around the world, often resulting in blindness. (2020-10-27)

Research team discovers molecular processes in kidney cells that attract and feed COVID-19
What about the kidneys make them a hotspot for COVID-19's cytokine storm? A research team says it's the presence of a protein found on specialized renal transport cells. (2020-10-23)

Molecular processes in kidney cells may 'prime' diabetics for COVID-19 infection
People with diabetes -- especially those with diabetic kidney disease -- are among the most at risk for COVID-19. A new study peered inside the kidney cells of COVID-19 patients and diabetic kidney disease patients and made a surprising discovery: Similar molecular processes were activated in both sets of patients. The results suggest that diabetes may predispose patients to SARS-CoV-2 infection or more severe COVID-19 by spurring biological processes used by the virus to infect and replicate. (2020-10-23)

Common treatment for diabetic macular edema not effective in Black individuals
A medication frequently used to treat diabetic macular edema, which is the most common cause of blindness in people with diabetes, is less effective when used to treat the condition in Black patients, new study results show. (2020-10-22)

A CNIO team describes how a virus can cause diabetes
* CNIO researchers have discovered the molecular mechanism by which coxsackievirus type B4 affects the functions and identity of beta cells that generate insulin, therefore promoting diabetes * They suggest to explore whether the potential of some drugs tested for cancer treatment in combination with antiviral therapies could be effective as a prevention and therapeutic strategy * The finding could be relevant to face the COVID-19 pandemic, since recent clinical information indicates that the SARS-CoV-2 virus might also promote diabetes in some patients (2020-10-20)

Oncotarget: Rapid onset type 1 diabetes with anti-PD-1 directed therapy
Volume 11, Issue 28 of Oncotarget features 'Rapid onset type 1 diabetes with anti-PD-1 directed therapy', by Yun et al. and reported that Type 1 diabetes is a rare immune-related adverse event caused by checkpoint inhibitors with serious risk for diabetic ketoacidosis. (2020-10-09)

New efficacies of Ganoderma lucidum: Treatment of skin conditions like atopic dermatitis
Ganoderma lucidum, known as Yeongji mushroom in Korea, has long been used medicinally in China, Japan and Korea. Ganoderic acid, an active ingredient found in the mushroom, is known for its excellence in enhancing the immune function of cells. The Korean research team determined the conditions for enhancing the anti-inflammatory, anti-diabetic, and antioxidant effects of Ganoderma lucidum and confirmed its marketability as an anti-inflammatory agent for the skin. (2020-10-07)

Targeting our second brain to fight diabetes
Patrice Cani (UCLouvain) and Claude Knauf (INSERM) have discovered a 'jammer' that blocks communication between the gut and the brain, thus preventing proper regulation of sugar and causing insulin resistance in people with diabetes. They also discovered that a lipid produced by our body helps prevent this dysfunction and regulate sugar level, thus mitigating diabetes and intestinal inflammation. These discoveries, published in the scientific journal GUT, are major, because today one in two Europeans is overweight and one in ten has diabetes. (2020-10-06)

Discovery holds potential for reversing vision loss
Scientists at the Oklahoma Medical Research Foundation have identified a compound that could reverse the vision loss that occurs when blood vessels in the eyes of premature infants and adults grow out of control. (2020-10-05)

Diabetes drug boosts survival in patients with type 2 diabetes and COVID-19 pneumonia
Sitagliptin, a drug to lower blood sugar in type 2 diabetes, also improves survival in diabetic patients hospitalized with COVID-19, suggests a multicenter observational study in Italy. Patients given sitagliptin in addition to insulin had a mortality rate of 18 percent as compared with 37 percent in matched patients receiving only insulin. Led by Paolo Fiorina, MD, PhD, of Boston Children's Hospital, the study involved seven Italian hospitals during the first surge of COVID cases last spring. (2020-09-29)

High-intensity interval training combining rowing and cycling improves insulin sensitivity, body composition and cardiorespiratory fitness in obesity and type 2 diabetes
New research presented at this year's annual meeting of the European Association for the Study of Diabetes (EASD) shows that high-intensity interval training (HIIT) combining cycling and rowing markedly improves insulin sensitivity, body composition and cardiorespiratory fitness in cases of obesity and type 2 diabetes (T2D) (2020-09-23)

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