Current Diabetic Retinopathy News and Events | Page 25

Current Diabetic Retinopathy News and Events, Diabetic Retinopathy News Articles.
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Autologous bone marrow-derived mononuclear cell transplants can reduce diabetic amputations
This study evaluated the safety and efficacy of inter-arterial administration of autologous bone marrow-derived mononuclear cells into 20 diabetic patients with severe below-the-knee arterial ischemia. The researchers noted that surgical or endovascular revascularization options for patients such as those in the study were limited because of poor arterial outflow. The researchers concluded that the test procedure was safe and generated a significant increase in the vascular network in ischemic areas while promoting clinical improvement. (2012-04-18)

Licorice root found to contain anti-diabetic substance
Researchers have discovered a promising anti-diabetic substance in the amorfrutin class of natural substances. (2012-04-17)

Study compares sleeve gastrectomy with medical treatment in obese patients with type 2 diabetes
A study comparing a bariatric surgical procedure with conventional medical treatment in morbidly obese patients with type 2 diabetes mellitus suggests that surgery was associated with remission or improvement in diabetes-related outcomes, according to a report published Online First by Archives of Surgery, a JAMA Network publication. (2012-04-16)

Heart failure patients with diabetes may benefit from higher glucose levels
A new UCLA study found that for advanced heart failure patients with diabetes, having higher blood glucose levels may actually help improve survival rates. (2012-04-09)

Maternal obesity, diabetes associated with autism, other developmental disorders
A major study of the relationships between maternal metabolic conditions and the risk that a child will be born with a neurodevelopmental disorder has found strong links between maternal diabetes and obesity and the likelihood of having a child with autism or another developmental disability. (2012-04-09)

Study reports 2-year outcomes of diabetic macular edema treatment
A randomized controlled trial involving patients with persistent clinically significant diabetic macular edema (swelling of the retina) suggests the greater efficacy of bevacizumab compared with macular laser therapy that was previously demonstrated at 12 months was maintained through 24 months, according to a report published online first by Archives of Ophthalmology, a JAMA Network publication. (2012-04-09)

Sugar production switch in liver may offer target for new diabetes therapies
In their extraordinary quest to decode human metabolism, researchers at the Salk Institute for Biological Studies have discovered a pair of molecules that regulates the liver's production of glucose -- the simple sugar that is the source of energy in human cells and the central player in diabetes. (2012-04-08)

How a cancer drug leads to diabetes
The drug known as rapamycin is widely used by cancer and transplant patients. But, it also comes with a downside: rapamycin leads to diabetes in as many as 15 percent of the people who take it. Now, researchers reporting in the April Cell Metabolism, a Cell Press publication, have figured out why that is. The drug turns the insulin signal off in muscle, to prevent muscle cells from taking blood sugar in. (2012-04-03)

Study reveals how cancer drug causes diabetic-like state
Scientists at Dana-Farber Cancer Institute have discovered why diabetic-like symptoms develop in some patients given rapamycin, an immune-suppressant drug that also has shown anti-cancer activity and may even slow aging. (2012-04-03)

New hormone for lowering blood sugar
New evidence points to a hormone that leaves muscles gobbling up sugar as if they can't get enough. That factor, which can be coaxed out of fat stem cells, could lead to a new treatment to lower blood sugar and improve metabolism, according to a report in the April issue of Cell Metabolism, a Cell Press publication. (2012-04-03)

Tiny electrical sensors could signal faster MRSA diagnosis
A simple test to identify MRSA in wounds could identify the superbug quickly and help prevent infection from spreading. Scientists have developed the test to show whether wounds or lesions are infected with bacteria and if MRSA is present. (2012-03-29)

Vitamin D-fortified yogurt drink may lower risk of heart disease in type 2 diabetics
Daily intake of vitamin D-fortified doogh (Persian yogurt drink) improved inflammatory markers in type 2 diabetics and extra calcium conferred additional anti-inflammatory benefits, according to a recent study accepted for publication in the Endocrine Society's Journal of Clinical Endocrinology and Metabolism. (2012-03-29)

iCo Therapeutics and JDRF team up to support iDEAL trial for diabetic macular edema
iCo Therapeutics, a Vancouver-based drug reprofiling company and JDRF, the largest charitable funder of Type 1 diabetes research have joined forces to investigate a potential new treatment for one of the most common complications of diabetes, diabetic macular edema. The iDEAL study is a Phase II clinical trial to evaluate whether the drug iCo-007 could help to treat DME in people with either T1D or Type 2 diabetes. (2012-03-28)

Cleveland Clinic study shows bariatric surgery improves, reverses diabetes
Overweight, diabetic patients who underwent bariatric surgery achieved significant improvement or remission of their diabetes, according to new research from Cleveland Clinic. In a randomized, controlled trial, some weight loss surgery patients achieved normal blood sugar levels without use of any diabetes medications. In others, the need for insulin to control blood sugar was eliminated. (2012-03-26)

New evidence links Alzheimer's disease and diabetes
An emerging body of research suggests that Alzheimer's disease may be linked to insulin resistance, constituting a third type of diabetes. This model is based on several observations including an increased risk of developing Alzheimer's disease for diabetic patients, and reduced insulin levels in the brain tissue of Alzheimer's disease patients. Though intriguing, the existing evidence does not reveal if defective insulin signaling is causative of Alzheimer's or how insulin resistance impacts cognitive function. (2012-03-20)

Blood vessel disease of retina may be marker of cognitive decline
Women 65 or older who have even mild retinopathy, a disease of blood vessels in the retina, are more likely to have cognitive decline and related vascular changes in the brain, according to a multi-institutional study led by scientists at the University of California, San Francisco. (2012-03-15)

Eye health is related to brain health
People with mild vascular disease that causes damage to the retina in the eye are more likely to have problems with thinking and memory skills because they may also have vascular disease in the brain, according to a study published in the March 14, 2012, online issue of Neurology, the medical journal of the American Academy of Neurology. (2012-03-14)

Gene signal demonstrates activity of topical aganirsen in models of retinal neovascular disease
Aganirsen has demonstrated significant activity in two important models of retinal neovascular diseases, wet age-related macular degeneration and ischemic retinopathy. Gene Signal's Aganirsen is an antisense oligonucleotide that is expected to complete phase III trials for the treatment of progressive neovascularization in the cornea. These data, published online in Investigative Ophthalmology & Visual Science, demonstrate the ability of aganirsen to reach and exert activity on the retina when used topically, versus current solutions that require intra-vitreal injection. (2012-03-09)

Cardiologists identify mechanism that makes heart disease worse in diabetics
UT Southwestern Medical Center cardiologists have uncovered how a specific protein's previously unsuspected role contributes to the deterioration of heart muscle in patients with diabetes. Investigators in the mouse study also have found a way to reverse the damage caused by this protein. (2012-03-01)

Toward a personalized treatment against diabetes
Gathering experts from 21 European academic institutions and key players of the pharmaceutical industry, the DIRECT project (DIabetes REsearch for patient straTification) will focus on the stratification of patients with Type 2 diabetes in order to develop personalized treatments, that would therefore be more efficient. This 54 million Swiss franc project is supported by the Innovative Medicine Initiative, a joint program of the European Commission and the European Federation of Pharmaceutical Industries and Associations. (2012-02-22)

$70 million to close the gap on treatable Australian Indigenous eye health
Researchers from the University of Melbourne say $70 million could (2012-02-22)

Mayo Clinic: Prediabetes may not explain diabetic polyneuropathies
In a reversal of two decades of medical reports, a Mayo Clinic study finds the frequency of nerve damage called diabetic polyneuropathy is similar in prediabetic patients and healthy people. Physicians should seek explanations other than prediabetes for patients who have painful small fiber polyneuropathy, the researchers say. The study was published in the February issue of Diabetes Care. (2012-02-21)

American Heart Association launches free-access online journal
Among findings posted in the inaugural publication of the American Heart Association's online-only, free-access scientific journal, the NIH Stroke Scale accurately identifies patients with the highest risk of death in the first month after stroke. Aspirin works as well as more expensive drugs in combination with a walking program to treat blocked leg arteries. Heart failure patients do better when they receive several evidence-based treatments at once. Kidney problems signal the highest death risk for people with type 2 diabetes. (2012-02-21)

University Hospitals receives $5 million gift for Eye Institute
The Elisabeth Severance Prentiss Foundation has made a $5 million gift to University Hospitals for the Eye Institute. The gift will support a variety of eye programs with a focus on retina and macular disease. (2012-02-17)

Pancreatic hormone linked with severe heart disease in obese and diabetic patients
Severe heart damage in people who are obese and diabetic is linked with a pancreatic hormone called amylin, UC Davis researchers have found. (2012-02-16)

The leading cause of death for diabetics: Getting to the heart of problem
Millions of people suffer from Type 2 diabetes. The leading cause of death in these patients is heart disease. Researchers have now identified, through their work in mice, a potential new therapeutic approach to reduce the prevalence of heart failure and improve the long-term survival of patients with Type 2 diabetes. (2012-02-13)

Breastfeeding can reduce risk of childhood obesity
Children of diabetic pregnancies have a greater risk of childhood obesity but new research from the Colorado School of Public Health shows breastfeeding can reduce this threat. (2012-02-08)

Diabetic kidney failure follows a 'ROCK'y road
A protein kinase known as ROCK1 can exacerbate an important process called fission in the mitochondria, the power plants of cells, leading to diabetic kidney disease, said researchers from Baylor College of Medicine. (2012-02-07)

Diabetes rates vary widely in developing countries, 1 in 10 cases untreated
Rates of diabetes vary widely across developing countries worldwide, according to a new analysis led by Dr. Longjian Liu of Drexel University's School of Public Health. Worldwide, four in five people with diabetes now live in developing countries. Liu's study found that access to healthcare support for diabetes varied widely in developing countries, and that one in 10 diagnosed cases remain untreated. The study is available online and will appear in the journal Diabetic Medicine. (2012-02-02)

Study: Diabetes affects hearing loss, especially in women
Having diabetes may cause women to experience a greater degree of hearing loss as they age, especially if the metabolic disorder is not well controlled with medication, according to a new study from Henry Ford Hospital in Detroit. Women between the ages of 60 and 75 with well-controlled diabetes had better hearing than women with poorly controlled diabetes, with similar hearing levels to those of non-diabetic women of the same age. (2012-01-26)

SUNY Downstate receives grant from research to prevent blindness
Capping SUNY Downstate Medical Center's growth into a major center for eye research, Research to Prevent Blindness has awarded SUNY Downstate a four-year challenge grant of $220,000 to spur the development of advanced research into the causes, treatment, and prevention of blinding diseases. Douglas R. Lazzaro, MD, professor and chair of ophthalmology, is the principal investigator. RPB is the world's leading voluntary organization supporting eye research. (2012-01-23)

First study using human embryonic stem cells for macular degeneration shows they are safe and lead to some vision improvement
The Lancet today reports the use of human embryonic stem cells to treat macular degeneration in human beings. It is the first report of the use of such cells in humans for any purpose. The study involved one elderly patient and one young patient with different forms of macular degeneration that had led to severe vision loss. (2012-01-23)

Joslin study identifies novel markers as key indicators of future renal failure in diabetes
Scientists at Joslin Diabetes Center have identified two novel markers that, when elevated in the blood stream, can predict accurately the risk of renal failure in patients with Type 1 and Type 2 diabetes. The findings have immediate diagnostic implications and can be used for the development of new therapies to prevent or postpone the progression of renal disease in diabetes. (2012-01-19)

Solving the mystery of an old diabetes drug that may reduce cancer risk
In a new paper published in the journal Cancer Prevention Research, researchers from McGill University and the University of Montreal report on how the diabetes drug metformin potentially reduces cancer risk. (2012-01-18)

Millennium Development Goal 4 focuses on child survival -- but what about the consequences for newborns that survive illness and complications in all world regions?
Many millions more babies are affected by illnesses and complications yet survive, and very little is known about of the risks of long-term impairment worldwide. A study published online first by the Lancet shows that more than one-third of babies with complications such as preterm birth, obstetric complications, jaundice or infections then suffer long-term developmental consequences. (2012-01-12)

KalVista and JDRF form research partnership for novel treatment of diabetic eye disease
KalVista Pharmaceuticals and JDRF have formed a research partnership focused on a novel approach being developed by KalVista to preserve vision and slow the progression of diabetic eye disease. Diabetic eye disease is one of the most common and most serious complications in people withType 1 diabetes. JDRF will provide up to $2.2 million in milestone-based financial support and research expertise to KalVista. (2012-01-09)

Insulin therapy may help repair atherosclerotic lesions in diabetic patients
New research reveals that insulin applied in therapeutic doses selectively stimulates the formation of new elastic fibers in cultures of human aortic smooth muscle cells. These results advance the understanding of the molecular and cellular mechanisms of diabetic vascular disease. The study is published in the February issue of the American Journal of Pathology. (2012-01-09)

Hydrogen sulfide reduces glucose-induced injury in kidney cells
Hydrogen sulfide, a noxious gas that smells like rotten eggs, may have beneficial effects in the kidney. Researchers at The University of Texas Health Science Center San Antonio found that this gas diminishes high glucose-induced production of scarring proteins in kidney cells. Considerable work remains to be done before studies can move to animal models. (2012-01-03)

Explaining heart failure as a cause of diabetes
Either heart failure or diabetes alone is bad enough, but oftentimes the two conditions seem to go together. Now, researchers reporting in the January Cell Metabolism appear to have found the culprit that leads from heart failure to diabetes and perhaps a novel way to break that metabolic vicious cycle. (2012-01-03)

DMP for diabetes type 2: Current guidelines indicate some need for revision
As a literature search for recommendations from current clinical practice guidelines of high methodological quality has shown, there is no compelling need for revision of any part of the disease management program for diabetes type 2. However, in its final report now published, IQWiG identified various aspects that could be supplemented and specified. (2012-01-03)

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