Current Diagnosis News and Events

Current Diagnosis News and Events, Diagnosis News Articles.
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3D biopsies to better understand brain tumors
Researchers at the Institut de Neurociències of the Universitat Autònoma de Barcelona (INc-UAB) obtained a highly accurate recreation of human glioblastoma's features using a novel 3D microscopy analysis. The study, published in the journal Acta Neuropathologica Communications, provides new information to help with the diagnose, by finding therapeutical targets and designing immunotherapeutical strategies. (2021-02-19)

Physical conditions linked to psychological distress in patients with cancer
Among patients with cancer, having additional physical comorbidities was linked with a higher risk of experiencing psychological distress. The finding comes from a Psycho-Oncology analysis of 2017 data from the National Health Survey of Spain. (2021-02-18)

A novel gel electrophoresis technique for rapid biomarker diagnosis via mass spectrometry
Polyacrylamide gel electrophoresis enables high-resolution separation of proteins extracted from biological samples, but it requires more than one day of pretreatment to recover the separated proteins trapped inside the gel for detection by mass spectrometry. BAC-DROP, our novel electrophoresis technology, uses a dissolvable form of polyacrylamide gel, which allows sample pretreatment to be completed in about 5 hours. The developed technology will enable the rapid diagnosis of viruses and disease protein markers. (2021-02-18)

Discovery of biomarker could help predict Alzheimer's years before symptoms emerge
A unique brain protein measured in the blood could be used to diagnose Alzheimer's disease decades before symptoms develop, according to new Edith Cowan University (ECU) research. (2021-02-17)

HKBU and CUHK launch Spermine Risk Score for prostate cancer diagnosis
Researchers from Hong Kong Baptist University (HKBU) and the Faculty of Medicine at The Chinese University of Hong Kong (CU Medicine) have jointly developed the Spermine Risk Score which, coupled with the use of a urine test, provides a non-invasive and more reliable method for the diagnosis of prostate cancer. In a study conducted by the researchers, about 37% of the patients, who were ultimately found to have no prostate cancer, can avoid undergoing a prostate biopsy procedure. (2021-02-08)

Tom Hanks' COVID-19 diagnosis likely shaped behaviors, thoughts toward virus
When actor Tom Hanks announced his COVID-19 diagnosis on March 11, 2020, many Americans were still learning about the virus and its severity. According to new research, Hanks' announcement may have affected how some people understood the virus and their behavior toward its prevention. (2021-02-05)

Study shows aspirin before a diagnosis may lower colorectal cancer mortality
A new study finds that long-term aspirin use before a diagnosis of colorectal cancer (CRC) may be associated with lower CRC-specific mortality. (2021-02-02)

Abnormal hyperactivation in the brain may be an early sign of Alzheimer's
A research team led by UdeM psychology and neuroscience professor Sylvie Belleville has just targeted an early biomarker of the disease. (2021-01-21)

Cells resistant to treatment already present before diagnosis of adult leukaemia
This work is a collaboration between Núria López-Bigas' lab at IRB Barcelona and the groups headed by Anna Bigas (Hospital del Mar Medical Research Institute) and Josep Maria Ribera (Josep Carreras Leukaemia Research Institute). The results have been published in Genome Biology. (2020-12-16)

Development of high-speed nanoPCR technology for point-of-care diagnosis of COVID-19
Researchers at IBS invented a new diagnostic method for COVID-19, called nanoPCR (2020-12-08)

Older adults with dementia exhibit financial 'symptoms' up to six years before diagnosis
A new study led by researchers at the Johns Hopkins Bloomberg School of Public Health and the Federal Reserve Board of Governors found that Medicare beneficiaries who go on to be diagnosed with dementia are more likely to miss payments on bills as early as six years before a clinical diagnosis. (2020-11-30)

Diagnosing the cause of exercise-induced respiratory symptoms
Exercise?induced respiratory symptoms are common in childhood, and it can be difficult to diagnose their cause. A study published in Pediatric Pulmonology found that the diagnoses proposed by primary care physicians are often not the same as the final diagnoses after specialist referrals. (2020-11-18)

Artificial intelligence-based tool may help diagnose opioid addiction earlier
Researchers have used machine learning, a type of artificial intelligence, to develop a prediction model for the early diagnosis of opioid use disorder. The advance is described in Pharmacology Research & Perspectives. (2020-11-18)

Weekly physical activity may help prevent mild cognitive impairment conversion to dementia
Exercising more than once per week is associated with a lower risk of developing Alzheimer's disease in patients with mild cognitive impairment, research published in the open access journal Alzheimer's Research and Therapy suggests. (2020-11-12)

Trial targets deadly lung cancer
With more than 650 Australians diagnosed with malignant mesothelioma last year, Flinders University is leading new research to discover alternatives to chemotherapy and even prevent deaths by early detection in future. One novel approach, using natural therapeutic benefits of curcumin, a key component of the spice turmeric, will be put to the test in a clinical trial in 2021 as part of world-leading research at Flinders University. (2020-10-30)

New approach to diagnosing genetic diseases using RNA sequencing increases yield
A new study from Baylor College of Medicine finds that starting genetic analysis with RNA sequencing can increase diagnostic yield and confidence in diagnosis. (2020-10-27)

User-friendly cucurbit downy mildew diagnosis guide suited for both experts and beginners
As the disease is rapid, infectious, and hard-to-diagnose, a team of plant pathologists with North Carolina State University and Michigan State University put together a clear and summarized guide to cucurbit downy mildew for beginners and experts. Accorded to Andres Salcedo, ''We realized the necessity to compile relevant and concise information about the causal agent of cucurbit downy mildew and developed a guide of multiple alternatives for its diagnosis and handling.'' (2020-10-21)

Major deficits in addressing mental health needs of asylum seekers
A new study of asylum seekers in Germany suggests that, among those with symptoms of depression, anxiety, or posttraumatic stress disorder (PTSD), few receive a diagnosis from the health care system, and of those diagnosed, many do not receive treatment. Amand Führer of Martin-Luther-University Halle-Wittenberg, Germany, and colleagues present these findings in the open-access journal PLOS ONE on October 7, 2020. (2020-10-07)

Treating DCIS with surgery and radiotherapy lowers cancer risk but benefits drop over time
A major study of women with DCIS - a breast condition that can become invasive cancer - has shown that surgery to remove the tissue followed by radiotherapy offers better protection compared to surgery alone. The study, presented at the 12th European Breast Cancer Conference, followed patients for up to 27 years. Although it shows that the benefit of radiotherapy and surgery over surgery alone persists, it also suggests that this benefit reduces over time. (2020-10-03)

Skoltech scientists discovered a new biomarker for liver cancer diagnosis
A group of Skoltech scientists led by a Skoltech and MSU professor Olga Dontsova discovered a novel liver-specific non-coding RNA. The researchers tracked the RNA amounts in a healthy liver and that affected by carcinogenesis and suggested using the RNA as a biomarker, thus creating a new panel of potential biomarkers for postoperative diagnosis of various liver cancers. (2020-09-30)

Screening UK Biobank blood samples identifies thousands of undiagnosed cases of type 2 diabetes
A study of approximately 200,000 blood samples from the UK Biobank has identified more than 2,000 undiagnosed cases of type 2 diabetes. The study is presented at this year's Annual Meeting of the European Association for the Study of Diabetes (EASD). (2020-09-20)

Metformin for type 2 diabetes patients or not? Researchers now have the answer
Metformin is the first-line drug that can lower blood sugar levels in type 2 diabetes patients. One third of patients do not respond to metformin treatment and 5 per cent experience serious side effects, which is the reason many choose to stop medicating. Researchers at Lund University in Sweden have now identified biomarkers that can show in advance how the patient will respond to metformin treatment via a simple blood test. (2020-09-17)

Physical diseases can negatively affect a depression
Patients with a first-time depression diagnosis have an increased risk of the disease worsening and requiring hospitalisation, if they have previously been treated for a physical disease at a hospital. This is shown by research from iPSYCH. (2020-09-16)

Epigenetic changes precede onset of diabetes
Epigenetic* changes in the islets of Langerhans of the pancreas can be detected in patients several years before the diagnosis of type 2 diabetes. These changes are responsible for the altered methylation activity of specific genes which differs from that in healthy individuals. In humans, 105 such changes have been discovered in blood cells. This was shown in a study by researchers from the DZD/DIfE, which has now been published in the journal Diabetes. (2020-09-10)

LSU Health New Orleans radiologists find chest X-rays highly predictive of COVID-19
A team of LSU Health New Orleans radiologists investigated the usefulness of chest x-rays in COVID-19 and found they could aid in a rapid diagnosis of the disease, especially in areas with limited testing capacity or delayed test results. (2020-09-03)

Depression worsens over time for older caregivers of newly diagnosed dementia patients
Caring for a partner or spouse with a new diagnosis of Alzheimer's or related dementia is associated with a 30% increase in depressive symptoms, compared to older adults who don't have a spouse with dementia -- and these symptoms are sustained over time, a new University of Michigan study found. (2020-09-02)

Study finds hospital-diagnosed overweight or obesity linked with markedly higher risk of death over 40 years
Individuals whose overweight or obesity is diagnosed in hospital are 60% more likely to die compared to the general population, according to a nationwide Danish study that followed over 1.9 million people for up to 40 years, being presented at The European and International Congress on Obesity (ECOICO), held online this year from 1-4 September. (2020-09-02)

EULAR: Timely detection of axial spondyloarthritis
Axial spondyloarthritis (axSpA) is associated with chronic back pain. Although the first symptoms frequently occur at an early age, often many years pass until the correct diagnosis is made. This is unsatisfactory as late diagnosis can lead to a poorer prognosis, more severe disease outcomes and delaying the start of effective therapies, thus impairing the quality of life of patients with axSpA. (2020-08-11)

New method to help spot gastric cancer cells
Researchers from the Shenyang Institute of Automation (SIA) of the Chinese Academy of Science (CAS) and City University of Hong Kong (CityU), in cooperation with doctors from the First Hospital of China Medical University, jointly proposed an optically induced electrokinetics (OEK) microfluidic method for label-free separation and characterization of gastric cancer cells. (2020-08-05)

New blood test shows great promise in the diagnosis of Alzheimer's disease
A new blood test demonstrated remarkable promise in discriminating between persons with and without Alzheimer's disease and in persons at known genetic risk may be able to detect the disease as early as 20 years before the onset of cognitive impairment, according to a large international study published today in the Journal of the American Medical Association (JAMA) and simultaneously presented at the Alzheimer's Association International Conference. (2020-07-28)

Higher end of normal blood platelet count could indicate cancer
Blood platelet counts at the higher end of normal suggest a high risk of cancer in men aged 60 or over, and should be investigated, according to new University of Exeter research. (2020-07-27)

Designed a new model to predict the life expectancy of a severe neurodegenerative disease
Researchers from IDIBELL, the University of Göttingen and the University of Münster, designed six tables, using data available at the time of diagnosis, where easily extrapolate patient's life expectancy. This model has been created with the world's largest cohort of patients with this disease, up to 1,200 patients registered since 1993. (2020-07-15)

Metabolomics meets genomics to improve patient diagnosis
Researchers at Baylor College of Medicine have improved their ability to identify the genetic cause of undiagnosed conditions. (2020-07-07)

IU School of Medicine study paves way for earlier autism diagnosis in Indiana
Led by Nancy Swigonski, MD and Mary Ciccarelli, MD, a team of faculty at Indiana University School of Medicine have developed a statewide early ASD screening and evaluation system in the primary care setting showing success in improving access to evaluations and lowering the age of diagnosis. This study, published July 6 in Pediatrics, is the first of its kind in the U.S. to include health care systems across an entire state. (2020-07-06)

Identified the genetic landscape of myelodysplastic/myeloproliferative neoplasms
Researchers from the MDS Group of the Josep Carreras Leukaemia Research Institute and the Munich Leukemia Laboratory map the mutations that can ease and accelerate the diagnosis of Myelodysplastic/Myeloproliferative Neoplasms rare malignancies. (2020-07-01)

Human-Artificial intelligence collaborations best for skin cancer diagnosis
Artificial intelligence (AI) improved skin cancer diagnostic accuracy when used in collaboration with human clinical checks, an international study including University of Queensland researchers has found. (2020-06-29)

Disproportionate effects of COVID-19 on socially vulnerable communities
Authors found that COVID-19 has disproportionately affected socially vulnerable communities, especially minority and non-English speaking ones. (2020-06-25)

Towards an AI diagnosis like the doctor's
Artificial intelligence is an important innovation in diagnostics, because it can learn to recognize abnormalities that a doctor would also label as a disease. But the way these systems work is opaque, and doctors have a better ''overall picture'' when they make the diagnosis. In this publication, Radboudumc researchers show how they can make the AI show how it's working, as well as let it diagnose more like a doctor, thus making AI more relevant to clinical practice. (2020-06-24)

Simple blood test could one day diagnose motor neurone disease
Scientists at the University of Sussex have identified a potential pattern within blood which signals the presence of motor neuron disease; a discovery which could significantly improve diagnosis. (2020-06-17)

Yale scientists propose explanation for baffling form of childhood OCD
Yale scientists may have found a cause for the sudden onset of obsessive-compulsive disorder (OCD) in some children, they report. Pediatric autoimmune neuropsychiatric disorders, or PANDAS, were first proposed in the 1990s. Thought to be triggered by streptococcal infections, they account for an unknown portion of youth OCD cases. But the biology underpinning this disorder has baffled scientists. (2020-06-16)

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