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Current Dialysis News and Events, Dialysis News Articles.
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Acute kidney disease in critically ill COVID-19 patients
A current study [1] is the first to evaluate and characterize the occurrence of COVID-19-associated acute kidney injury (AKI) in a larger number of critically ill patients. The study has been published in CKJ. AKI developed in a total of 80% of the patients after admission, and day 14 renal recovery occurred in only 52% of those affected. (2020-06-08)

Specific kidney proximal tubular injury caused by SARS-CoV-2
A French study [1] investigated acute Fanconi syndrome as a kidney injury associated with COVID-19. The hallmark of the syndrome is increased excretion or loss of certain substances (such as protein, phosphate or glucose) in urine. This renal dysfunction often precede acute kidney injury and disappears again when the kidneys recover. (2020-06-08)

Indirect effects of SARS-CoV-2 on the kidneys: beware of the genetic background
A current study [1] reports on two COVID-19 patients with acute kidney injury. The virus was detected in throat swabs only, but not in kidney tissue, so it is suspected that inflammatory or immunological reactions are the cause, particularly in people with a certain genetic predisposition. (2020-06-08)

Hope for patients with primary hyperoxaluria type 1
Lumasiran is a subcutaneously administered RNAi therapeutic targeting hydroxyacid oxidase 1 (HAO1) - the gene encoding glycolate oxidase (GO) - in development for the treatment of primary hyperoxaluria type 1 (PH1). The drug has not yet received approval from the European Medicines Agency (EMA) or other health authorities. The data presented today at the ERA-EDTA Congress have been submitted to regulators in support of applications for such approvals. (2020-06-07)

Researchers find TEG test can identify undetected blood clots in COVID-19 ICU patients
Researchers at Baylor College of Medicine are recommending that all COVID-19 patients admitted to the ICU undergo a thromboelastography (TEG) to test for the risk of forming blood clots. This recommendation comes after they found that more than half of the patients tested under these same conditions developed clinically significant blood clots that went undetected using routine screenings. (2020-06-05)

Are kidney transplant patients at higher risk? The European experience
The risk of death is relatively high in kidney transplant patients admitted to hospital with COVID-19. Advanced age is the most important risk factor for death but, unlike in the general population, male sex, diabetes and cardiovascular disease do not appear to increase this risk. Younger, healthier patients may not be at special risk if they adhere strictly to hygiene and social distancing advice. (2020-06-05)

COVID-19 mortality alarmingly high in dialysis patients
Analysis of a Spanish experience shows that COVID-19 is frequent in hemodialysis patients, who appear to be at risk for worse outcome. A dramatic finding from the own experience, register and published papers from Spain is that the risk of dialysis patients dying of COVID-19 is very high at 1:4. These patients require special protection, and routine unconditional tests should be carried out on patients and staff in dialysis units. (2020-06-05)

Acute kidney injury and end stage kidney disease in severe COVID-19
Many COVID-19 patients experience hematuria, proteinuria and elevated serum creatinine concentration early in the course of the disease. Furthermore, acute kidney injury is a relevant clinical complication in patients with Covid-19 and is associated with a poor prognosis. An autopsy study from Hamburg shows that the novel coronavirus also affects the kidneys. Renal parameters may have prognostic relevance for the course of COVID-19. (2020-06-05)

Device simulates filtering and ion transport functions of human kidney
University of Arkansas researchers have developed a device that simulates the blood filtering and ion transport functions of the human kidney. The technology could transform treatment options for people in the final stage of renal disease. (2020-05-27)

Measuring blood damage
Red blood cells sometimes rupture when blood is sent through faulty equipment, such as a dialysis machine. This is called hemolysis. Hemolysis also can occur during blood work when blood is drawn too quickly through a needle, leading to defective laboratory samples. University of Delaware mechanical engineer Tyler Van Buren and collaborating colleagues at Princeton University have developed a method to monitor blood damage in real-time. (2020-05-21)

IU School of Medicine study tracks COVID-19 spread in pediatric dialysis unit
As COVID-19 continues its sweep around the globe, dialysis units have continued to be hotspots for the virus' spread. Researchers at Indiana University School of Medicine hope to combat that threat, through a novel study published in JAMA. The study, conducted by members of the Pediatric Nephrology Dialysis Unit at Riley Hospital for Children at IU Health, used antibody testing on patients, doctors, nurses and staff within the unit to track symptomatic and asymptomatic spread in a confined space. (2020-05-14)

Research suggests new therapeutic target for kidney diseases
Researchers have published a new study that suggests a signaling pathway called ROBO2 is a therapeutic target for kidney diseases, specifically kidney podocyte injury and glomerular diseases. (2020-05-04)

Wake Forest Baptist shares key elements needed in setting up designated COVID-19 unit
In an effort to rapidly provide specialized care for patients with coronavirus-like symptoms while protecting the safety of health care workers, doctors at Wake Forest Baptist Health created a special respiratory isolation unit from an existing 24-bed medical-surgical unit in the hospital in Winston-Salem. (2020-04-30)

A world first: Assessing kidney quality before transplantation using photoacoustic imaging
Demand for kidney transplants is so high that doctors now routinely accept damaged donor kidneys, with limited means to assess their quality. A new, non-invasive, photoacoustic imaging technique allows doctors to 'see' kidney scarring quickly and accurately with a simple scan. An upcoming, landmark clinical trial will test the new technique on donor kidney quality. The technology could potentially empower doctors to better match donor kidneys to patient life expectancy for longer-lasting transplantation outcomes. (2020-04-30)

Is it wrong to prioritize younger patients with COVID-19?
With services overburdened, healthcare professionals are having to decide who should receive treatment. But is it wrong to prioritise younger patients with COVID-19? Two experts debate the issue in The BMJ this week. (2020-04-22)

Drug shows promise in reversing kidney damage caused by lupus
A drug used for cancer therapy has shown promise in reversing kidney damage caused by systemic lupus erythematosus (SLE, or lupus), according to a Yale-led study published April 8 in the journal Science Translational Medicine. (2020-04-08)

Empowering rural doctors to treat advanced heart failure improves patient outcomes
Travel restrictions imposed to curb the spread of COVID-19 are making it more difficult for some heart failure patients who have artificial heart pumps to participate in follow-up care at implantation centers far from their homes. But a new study suggests there may be a viable alternative. According to University of Utah Health researchers, local doctors in rural areas who receive specialized training in managing the devices can care for these patients safely and effectively. (2020-03-30)

American Society of Nephrology provides insights on COVID-19 and kidney disease
The American Society of Nephrology has launched several initiatives to provide guidance on COVID-19 as it relates to the care of patients with kidney disease. (2020-03-30)

Distance to transplant center and likelihood of being considered for transplantation
In an analysis of information on adults who began treatment for kidney failure at any Georgia, North Carolina, or South Carolina dialysis facility, the distance from a patient's residence to the nearest transplant center did not appear to affect the likelihood of transplant-related referrals and evaluations. (2020-03-24)

Elderly patients also benefit from kidney transplantation
So far, kidney transplantation has generally not been offered to elderly patients (>75 years) because of the perioperative risks. Nor has it been clearly established whether transplanted patients in this age benefit significantly. In a new study published in NDT, the graft survival proved to be excellent, and nearly all patients remained dialysis-free. Is it time to rethink established common practice? (2020-02-26)

Valley physicians pioneer groundbreaking technology to help dialysis patients
Phoenix-area kidney specialist Randy Cooper, MD, will present his initial four-year data on a new type of dialysis access called Ellipsys at the upcoming American Society for Diagnostic and Interventional Nephrology (ASDIN), February 21-23, in Las Vegas. (2020-02-24)

Thousands of uninsured kidney disease patients strain Texas emergency departments
More than 10,000 uninsured patients sought care at Texas emergency departments for lifesaving kidney dialysis in 2017, incurring more than $21.8 million in hospital costs, according to researchers from UTHealth. (2020-02-19)

Kidney patients benefit using organs from Hepatitis C-infected donors
Kidney patients benefit by accepting kidneys from donors with hepatitis C, according to a University of Cincinnati physician-researcher. Making the choice reduces organ wait time for kidney patients while saving money over the long run. It also improves the quality of life and life expectancy for kidney patients. (2020-02-17)

Steroids could do more harm than good in treating coronavirus
Steroids should be avoided in the treatment of the current novel coronavirus, experts have advised. A commentary article published in The Lancet concludes that, based on evidence from previous outbreaks of similar types of infection such as SARS, steroids provide little benefit to patients and could do more harm than good. They say that clinicians should still administer the treatment for conditions such as asthma and other inflammatory diseases. (2020-02-06)

IDIBELL researchers discover that a molecule of blood is effective against autoimmune kidney disease
A research team from IDIBELL identifies C3BP (beta-) as a potential treatment for lupidic nephritis in an animal model. (2020-02-03)

UL study reveals 'identical' survival for kidney dialysis patients using different treatments
University of Limerick, Ireland, study reveals 'identical' survival rates for kidney dialysis patients using different forms of treatment. (2020-01-28)

Discovery of gene that modifies the severity of inherited kidney disease
Scientists have developed a new way to understand complex genetic diseases and have identified a gene that modifies the severity of inherited kidney disease, paving the way for personalized treatments. (2020-01-09)

Heart transplants from donors with hepatitis C may be safe and could help decrease organ shortage
One-year survival was 90% for adults with severe heart failure who received a heart transplant from a donor with hepatitis C, which was nearly identical to those who received a heart from donors who did not have hepatitis C (91%). Rates of organ rejection, stroke and kidney dialysis were similar between the two groups. More research is needed to assess longer-term results, however, increased use of hearts from donors with hepatitis C could help overcome the national shortage of donor organs. (2020-01-08)

Online patient tool is associated with increased likelihood of receiving kidney transplant
Patients with kidney failure who actively used an online patient portal to track the status of their health care improved their chances of getting a kidney transplant and shortened their wait times for an operation. (2020-01-08)

How do outcomes for in-hospital cardiac arrest differ in patients treated with dialysis?
Among patients who experience cardiac arrest while in the hospital, those on dialysis were less likely to have a shockable rhythm and more likely to be outside of the intensive care unit at the time of arrest compared with patients not on dialysis. Patients on dialysis had lower scores for resuscitation quality. Patients on dialysis had a similar likelihood of surviving to hospital discharge, and they had better neurological function at the time of discharge. (2020-01-07)

Number of people in need of renal replacement therapy is rising
The 2017 Annual Report of the ERA-EDTA Registry [1] reveals that only a small fraction of patients accepted for renal replacement therapy are able to start this treatment with the best available therapy, which is transplantation, -- and that the number of people who are in need of renal replacement therapy is rising. This poses a major challenge to our health systems, therefore everything should be done to fight this trend, e.g. by strengthening prevention. (2019-12-19)

Two-year ellipsys data featured at annual Controversies in Dialysis Access (CiDA) Meeting
A landmark two-year follow-up study on the Ellipsys® Vascular Access System was highlighted at the annual Controversies in Dialysis Access (CiDA) meeting, one of the premier dialysis access medical conferences in the world. (2019-12-18)

Kidney patients report positive experiences with novel approach to dialysis access
A new study reports high levels of patient satisfaction with a minimally invasive approach to creating vascular access for kidney patients who require hemodialysis. (2019-12-05)

Robotic transplants safe for kidney disease patients with obesity
Researchers report that among patients with obesity, robotic kidney transplants produce survival outcomes comparable to those seen among nonobese patients. The study includes data collected over 10 years from more than 230 robotic-assisted kidney transplants in patients with obesity. (2019-11-19)

High-protein diets may harm your kidneys
High protein intake is believed to be healthy, but it may pave the way to irreversible kidney failure. The risk of the kidneys being harmed by a diet rich in proteins is especially high in people with a pre-existing low-grade chronic kidney disease, of which most of the affected people are unaware. ''It is essential that people know there is another side to high-protein diets.'' (2019-11-18)

Bisphenol-a structural analogues may be less likely than BPA to disrupt heart rhythm
Some chemical alternatives to plastic bisphenol-a (BPA), which is still commonly used in medical settings such as operating rooms and intensive care units, may be less disruptive to heart electrical function than BPA, according to a pre-clinical study that explored how the structural analogues bisphenol-s (BPS) and bisphenol-f (BPF) interact with the chemical and electrical functions of heart cells. (2019-11-14)

Combined tests can predict kidney injury risk in critically ill children
Combining the Renal Angina Index and measurement of urinary Neutrophil Gelatinase Associated Lipocalin can improve predictions of severe acute kidney injury in critically ill children. Results from the study will be presented at ASN Kidney Week 2019 Nov. 5-10 at the Walter E. Washington Convention Center in Washington, D.C. (2019-11-10)

Hospitalizations among dialysis patients are higher in areas with more black residents
Patients receiving hemodialysis at facilities located in residential areas with a high percentage of Black residents have a higher rate of hospitalization. Results from the study will be presented at ASN Kidney Week 2019 Nov. 5-10 at the Walter E. Washington Convention Center in Washington, D.C. (2019-11-09)

Automated wearable artificial kidney may improve peritoneal dialysis
Peritoneal dialysis performed with an automated wearable artificial kidney was safe and effective for removing toxins from the blood of patients with kidney failure. Results from the study will be presented at ASN Kidney Week 2019 Nov. 5-10 at the Walter E. Washington Convention Center in Washington, D.C. (2019-11-08)

Community house hemodialysis offers many benefits to patients with kidney failure
Community house hemodialysis is a dialysis modality that overcomes many of the barriers to home hemodialysis. Results from the study will be presented at ASN Kidney Week 2019 Nov. 5-10 at the Walter E. Washington Convention Center in Washington, D.C. (2019-11-07)

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