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Current Disease Therapy News and Events, Disease Therapy News Articles.
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New study finds that proton therapy has fewer side effects in esophageal cancer patients
New research has found that esophageal cancer patients treated with proton therapy experienced significantly less toxic side effects than patients treated with older radiation therapies. (2015-05-22)

Can psychosocial treatments help autistic adults?
Multimillion dollar grant will fund study to assess if nondrug therapies improve the quality of life for adults with autism spectrum disorder. (2015-05-20)

Apremilast in plaque psoriasis and psoriatic arthritis: No added benefit can be derived
The dossiers contained neither data from studies of direct comparisons nor indirect comparisons. The manufacturer itself also did not claim an added benefit for its new drug. (2015-05-19)

Menopausal hormone therapy increases risk of gastrointestinal bleeding
Current users of menopausal hormone therapy are more than twice as likely than non-users to develop lower gastrointestinal bleeding and ischemic colitis, especially if they use the therapy for longer durations, according to a study that was released today at Digestive Disease Week® 2015. (2015-05-18)

Lives could be saved with hepatitis C treatment
In a letter to the Medical Journal of Australia published today, a Monash University-led team is asking for hepatitis C virus patients to gain improved access to drugs to prevent liver related deaths. (2015-05-17)

ASGCT Annual Meeting: Ana Buj Bello receives the Outstanding New Investigator Award
Dr. Ana Buj Bello, Inserm research scientist and head of the neuromuscular disorders team at Genethon, received the Outstanding New Investigator Award from the American Society of Gene & Cell Therapy (ASGCT) at the 18th Annual Meeting (May 13-16, 2015/New Orleans). This award recognizes four researchers every year for the quality and importance of their work in gene and cell therapy. (2015-05-15)

Minimal residual disease alone not predictive in T-cell leukemia
Researchers found that the presence of a few remaining leukemia cells, called minimal residual disease (MRD), at the end of induction chemotherapy was not predictive of risk or outcome in children with T-cell acute lymphoblastic leukemia (ALL). This opens the possibility for patients with T-cell ALL who have MRD to achieve complete remission without undergoing intensified cancer treatments and their associated toxicities. (2015-05-14)

Safety switch preserves beneficial effects of cell therapy
Researchers in the Center for Cell and Gene Therapy at Baylor College of Medicine, Houston Methodist and Texas Children's Hospital have found that a single dose of an otherwise harmless drug can safely control the severe and often lethal side effects associated with haploidentical stem cell transplantation. (2015-05-14)

Moffitt researchers say androgen deprivation therapy may lead to cognitive impairment
Cognitive impairment can occur in cancer patients who are treated with a variety of therapies, including radiation therapy, hormone therapy, and chemotherapy. After chemotherapy treatment it is commonly called 'chemo brain.' Signs of cognitive impairment include forgetfulness, inability to concentrate, problems recalling information, trouble multi-tasking and becoming slower at processing information. The number of people who experience cognitive problems following cancer therapy is broad, with an estimate range of 15 to 70 percent. (2015-05-13)

Japanese Society for Dialysis Therapy to publish Renal Replacement Therapy with BioMed Central
BioMed Central is pleased to partner with the Japanese Society for Dialysis Therapy in publishing the open-access journal Renal Replacement Therapy. The journal will publish its first articles in late 2015. (2015-05-11)

Combined radiation and hormonal therapy improves survival in node-positive prostate cancer
A new study finds that men with prostate cancer that has spread to nearby lymph nodes can benefit from the addition of radiation therapy to treatments that block the effects of testosterone. The findings imply that the almost half of patients with node-positive disease nationwide who this study found had not received combination therapy were not receiving the treatment that could best control their tumor and possibly save their lives. (2015-05-11)

Epilepsy drug could help treat Alzheimer's disease
University of British Columbia researchers say a new epilepsy drug holds promise as a treatment for Alzheimer's disease. (2015-05-07)

The dark side of cannabis
Although the use of cannabis as a medical drug is currently booming, we should not forget that leisure time consumption -- for example, smoking weed -- can cause acute and chronic harms. These include panic attacks, impaired coordination of movement, and nausea, as Eva Hoch and colleagues show in a topical review article in Deutsches Ärzteblatt International. (2015-05-05)

Researchers get a closer look at how the Huntington's gene works
A closer look at the DNA around the Huntington's disease gene offers researchers a new understanding of how the gene is controlled and how this affects the disease. These findings set the stage for new treatments to delay or prevent the onset of this devastating brain disease. (2015-05-04)

New gene editing tools force renewed debate over therapeutic germline alteration
Recent evidence demonstrating the feasibility of using novel CRISPR/Cas9 gene editing technology to make targeted changes in the DNA of human embryos is forcing researchers, clinicians, and ethicists to revisit the highly controversial issue of altering the inherited human genome. A provocative Editorial exploring the current technical limitations, safety concerns, and moral acceptability of therapeutic germline gene editing is published in Human Gene Therapy. (2015-05-01)

Gene variants show potential in predicting rheumatoid arthritis disease outcomes
Arthritis Research UK-funded scientists at the University of Manchester have identified a new way in which genotyping can be used to predict disease outcomes among sufferers of rheumatoid arthritis. (2015-04-29)

Diffusion tensor MR tractography effective as quantitative tool, treatment marker response
MR tractography may be a reliable quantitative imaging biomarker to assess prostate cancer treatment response to androgen deprivation and radiation therapy. (2015-04-24)

Reporting Agatston scores with chest CT leads to cardiovascular risk reclassification
The assessed risk of more than 65 percent of patients without established cardiovascular disease who were evaluated for coronary artery calcification via ungated chest CT was reclassified after undergoing Agatston-scored ungated CT scans. (2015-04-23)

All-oral, DAA options for HCV effective and well tolerated in patients with decompensated cirrhosis
Interim data presented today at The International Liver CongressTM 2015 from the HCV-TARGET study show that all-oral, direct-acting antiviral therapy for hepatitis C is well tolerated and highly effective in patients with decompensated cirrhosis. Sustained virologic response at four weeks was shown to be: sofosbuvir/ribavirin: 75 percent; sofosbuvir/simeprevir: 77 percent; sofosbuvir/simeprevir/ribavirin: 81 percent. (2015-04-23)

Eligible for breast conserving therapy, many still choose mastectomy
New research led by Brigham and Women's Hospital finds that breast conserving therapy -- or the removal of less breast tissue via a lumpectomy -- was successful in more than 90 percent of patients with triple-negative breast cancer who became eligible for this procedure after treatment with chemotherapy. Despite these findings, 31 percent who were eligible for breast conserving therapy chose to have the entire breast removed via mastectomy. (2015-04-23)

UTMB investigates use of oxygen therapy among COPD patients
A new study about the use of oxygen to treat chronic obstructive pulmonary disease from The University of Texas Medical Branch at Galveston found that the majority of patients receiving oxygen therapy were low-income, non-Hispanic white females about 75 years old with two or more other health conditions. The UTMB study is the first to describe the current use of oxygen therapy among COPD patients in a large, nationally representative sample of US patients. (2015-04-23)

What happens when multiple sclerosis patients stop taking their medication?
According to researchers, we know a lot about what happens when therapy is started, but we know very little about what happens when therapy is stopped. (2015-04-21)

Study shows feasibility of using gene therapy to treat rare immunodeficiency syndrome
In a small study that included seven children and teens with Wiskott-Aldrich syndrome, a rare immunodeficiency disorder, use of gene therapy resulted in clinical improvement in infectious complications, severe eczema, and symptoms of autoimmunity, according to a study in the April 21 issue of JAMA, a theme issue on child health. (2015-04-21)

NEJM editorial: New studies about endovascular therapy for stroke represent paradigm shift
In an editorial, titled 'Endovascular Stroke Therapy: It's About Time,' Anthony Furlan, M.D., states that five new studies about endovascular stroke therapy demonstrate the therapy is highly beneficial in a 'resounding fashion.' (2015-04-17)

Yale launches national study of personalized medicine for metastatic melanoma
Yale University has launched a multicenter clinical trial, sponsored by Stand Up to Cancer and Melanoma Research Alliance, that will apply the latest in personalized medicine technology to treat metastatic melanoma. The trial, for which Yale is a lead site, will enroll patients lacking a particular genetic mutation for whom immune therapy did not work or was not an option. (2015-04-15)

LA BioMed 2015 Innovation Showcase
Join us for a full day of networking and learn about the latest developments on the efforts to bring to market technologies developed at LA BioMed. (2015-04-14)

Study: Gene therapy superior to half-matched transplant for 'bubble boy disease'
In new research published online today in Blood, the Journal of the American Society of Hematology reports that children with 'bubble boy disease' who undergo gene therapy have fewer infections and hospitalizations than those receiving stem cells from a partially matched donor. (2015-04-13)

Dodo bird verdict given new life by psychosis therapy study
A study by researchers at the University of Manchester and the University of Liverpool has examined the psychological treatment of more than 300 people suffering from psychosis, showing that, whatever the therapy, it is the relationship between the patient and therapist which either improves or damages wellbeing. (2015-04-10)

Early physical therapy for low back pain reduces costs, resources
A study in the scientific journal BMC Health Services Research shows that early and guideline adherent physical therapy following an initial episode of acute, nonspecific low back pain resulted in substantially lower costs and reduced use of health care resources over a two-year period. (2015-04-09)

Brittle bone disease: Drug research offers hope
New research at the University of Michigan offers evidence that a drug being developed to treat osteoporosis may also be useful for treating osteogenesis imperfecta or brittle bone disease, a rare but potentially debilitating bone disorder that that is present from birth. (2015-03-31)

Oxygen therapy in COPD patients is associated with burn injury
Researchers from the University of Texas Medical Branch at Galveston have found that patients with chronic obstructive pulmonary disease receiving home oxygen have a higher risk of burn injury. This study was published on March 30 in Mayo Clinic Proceedings. (2015-03-30)

Xpert MTB/RIF assay for the diagnosis of pulmonary tuberculosis in children: A systematic review and meta-analysis
Microbiological confirmation of childhood tuberculosis is rare because of the difficulty of collection of specimens, low sensitivity of smear microscopy, and poor access to culture. (2015-03-23)

The Michael J. Fox Foundation supports promising Parkinson's project
Australian scientists receive support from The Michael J. Fox Foundation for Parkinson's Research to speed progress in developing a novel therapy for Parkinson's disease. (2015-03-23)

Sweeping prostate cancer review upends widely held belief on radiation after surgery
Two new studies have upended the widely held view that it's best to delay radiation treatment as long as possible after the removal of the prostate in order to prevent unwanted side effects. (2015-03-23)

Discontinuing statins for patients with life limiting illness
Discontinuing statin use in patients with late-stage cancer and other terminal illnesses may help improve patients' quality of life without causing other adverse health effects, according to a new study by led by researchers at the University of Colorado Anschutz Medical Campus and Duke University and funded by the National Institute of Nursing Research. (2015-03-23)

Hormones with statins may help women's hearts after menopause
Hormones may not protect women from heart disease or stroke after menopause, but when combined with cholesterol-lowering statin drugs, they may help protect women from these killers, shows a population study from Sweden to be published in the April issue of Menopause, the journal of The North American Menopause Society. (2015-03-17)

Chronic bowel inflammation is diagnosed too late in children and adolescents
Cramping abdominal pains, diarrhea, bloody stools -- these are common symptoms of chronic inflammatory bowel disease. Every year, up to 1,470 children and adolescents in Germany develop the disease. But chronic inflammatory bowel disease is mostly diagnosed too late in these patients, as Stephan Buderus, Dietmar Scholz, and colleagues show in an original article in the current issue of Deutsches Ärzteblatt International. (2015-03-17)

Study finds baroreflex activation therapy effectively treats heart failure
Results of a clinical trial announced today at the American College of Cardiology Annual Scientific Session show a new type of therapy is safe and effective for symptomatic advanced heart failure patients who are already receiving optimum drug and device therapy. The study also published in the Journal of the American College of Cardiology Heart Failure. (2015-03-16)

Boosting a natural protection against Alzheimer's disease
Researchers at the University of California, San Diego School of Medicine have identified a gene variant that may be used to predict people most likely to respond to an investigational therapy under development for Alzheimer's disease. The study, published March 12 in Cell Stem Cell, is based on experiments with cultured neurons derived from adult stem cells. (2015-03-12)

Molecules in prostate tumors might predict whether RT can help prevent recurrence
A new study has identified a group of molecules in prostate-cancer cells that doctors might one day use to distinguish which patients should be treated with radiation therapy if rising PSA levels indicate their cancer has recurred after surgical removal of the prostate. (2015-03-11)

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