Current Drug Delivery News and Events | Page 25

Current Drug Delivery News and Events, Drug Delivery News Articles.
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Women experience high rates of health insurance 'churn' before and after childbirth
A high percentage of women in the US move in and out of health insurance coverage -- sometimes referred to as 'churn' -- in the months before and after childbirth, according to a new study from Harvard T.H. Chan School of Public Health. Low-income women experience the brunt of these insurance disruptions, which cause coverage gaps that can lead to adverse health outcomes. (2017-04-03)

Anti-cancer drug gets a boost when combined with antirheumatic
Scientists at EPFL and NTU have discovered that combining an anticancer drug with an antirheumatic produces improved effects against tumors. The discovery opens a new path for drug-drug synergy. (2017-03-30)

UAB creates triple-threat cancer-fighting polymer capsules for guided drug delivery
Chemists have designed triple-threat cancer-fighting polymer capsules that bring the promise of guided drug delivery closer to preclinical testing. These multilayer capsules show three traits that have been difficult to achieve in a single entity. They have good imaging contrast that allows detection with low-power ultrasound, they can stably and efficiently encapsulate the cancer drug doxorubicin, and both a low- and higher-power dose of ultrasound can trigger the release of that cargo. (2017-03-30)

LSTM reports on a new way of screening potential treatments for TB
Scientists from LSTM's Research Centre for Drugs and Diagnostics (RCDD) have described in a paper published today in Scientific Reports, a new way of screening potential treatments for Tuberculosis (TB) which may assist in the identification and prioritization of new therapies which could potentially reduce the duration of current TB treatment. (2017-03-29)

UNC to create and test injectable long-acting implant to prevent HIV/AIDS
Researchers at the University of North Carolina at Chapel Hill have received a three-year, $1.8 million grant from the National Institutes of Health to develop a new implantable drug delivery system for long-lasting HIV-prevention. (2017-03-24)

Study confirms prescription weight-loss medication helps with opiate addiction recovery
Researchers from the University of Texas Medical Branch at Galveston have confirmed that a prescription weight-loss pill decreases the urge to use opiates such as oxycodone. In a study published in ACS Chemical Neuroscience, the researchers led by UTMB scientist Kathryn Cunningham found that the drug, lorcaserin, reduced the use and craving for the opioid oxycodone in preclinical studies. (2017-03-24)

NIDA grant to develop brief intervention for gay male couples
Dr. Tyrel Starks, an Assistant Professor of Psychology at Hunter College and the Graduate Center of the City University of New York, and faculty affiliate of the Hunter College Center for HIV/AIDS Educational Studies and Training, has been awarded a three-year grant from the National Institute on Drug Abuse, totaling $666,900, to develop a couples-based drug use intervention for gay male couples. (2017-03-22)

Antenatal screening in Europe: How to avoid mother-to-child transmission of infections
Transmission of infections with HIV, hepatitis B, syphilis or rubella from mother to child before and during birth as well as in infancy still occur across Europe -- despite existing prevention methods. A new ECDC report outlines the cornerstones for effective antenatal screening programs across the EU/EEA countries. (2017-03-21)

Mutants in microgravity
A proof-of-concept investigation, Nanobiosym Genes, is sending two strains of Staphylococcus aureus bacteria to the International Space Station. (2017-03-20)

Orbital ATK Cygnus set to deliver research to space station
Orbital ATK is targeted to launch its Cygnus spacecraft into orbit for a resupply mission to the International Space Station March 24, 2017 from Cape Canaveral Air Force Station in Florida. (2017-03-20)

Minneapolis Heart Institute physician receives American College of Cardiology top honor
Cardiologist will receive the Douglas P. Zipes Distinguished Young Scientist Award for his commitment to improving patient care. His achievements will be recognized Sunday at the American College of Cardiology conference in Washington, DC. (2017-03-17)

Old target, new mechanism for overcoming tuberculosis resistance
In strains of tuberculosis that have developed drug resistance mutations, researchers have identified a secondary pathway that can be activated to reinstate drug sensitivity. (2017-03-16)

Nanoparticle paves the way for new triple negative breast cancer drug
A potential new drug to tackle the highly aggressive 'triple negative' breast cancer -- and a nanoparticle to deliver it directly into the cancer cells -- have been developed by UK researchers. (2017-03-16)

Scripps Florida scientists develop new drug delivery method for cancer therapy
Scientists from the Florida campus of The Scripps Research Institute (TSRI) have developed a new drug delivery method that produces strong results in treating cancers in animal models, including some hard-to-treat solid and liquid tumors. (2017-03-16)

Common tests for preterm birth not useful for routine screening of first-time pregnancies
Two methods thought to hold promise in predicting preterm delivery in first-time pregnancies identified only a small proportion of cases and do not appear suitable for widespread screening, according to a large study by a National Institutes of Health research network. (2017-03-14)

Study finds no benefit, but possible harm, from drug used to prevent preterm births
A drug commonly prescribed to pregnant women with a history of delivering babies early provides no benefit. In fact, this drug may even increase the risk of developing gestational diabetes. (2017-03-14)

Atomic map of malaria drug gives it new life
Researchers have mapped how the malaria drug mefloquine works, providing a route to make effective alternatives and combat rising drug resistance. (2017-03-13)

WSU researcher finds mechanism triggering spread of prostate cancer to bones
A Washington State University researcher has found a way that prostate cancer cells hijack the body's bone maintenance, facilitating the spread of bone cancers present in some 90 percent of prostate-cancer fatalities. (2017-03-13)

Atomic map gives malaria drug new lease on life
Researchers have for the first time mapped how one of the longest-serving malaria drugs works, opening the possibility of altering its structure to make it more effective and combat increasing malaria drug resistance. The study produced a precise atomic map of the frontline antimalarial drug mefloquine, showing how its structure could be tweaked to make it more effective in killing malaria parasites. (2017-03-13)

Convenient and easy to use glucose monitoring and maintenance
A research group from the Center for Nanoparticle Research within the Institute for Basic Science has developed a convenient and accurate sweat-based glucose monitoring and maintenance device. (2017-03-12)

Could a diabetes drug be used for Motor Neurone Disease?
A diabetes drug could one day be used to treat neurodegenerative diseases like Motor Neurone Disease (MND), Alzheimer's and Parkinson's. Researchers at Lancaster University are to conduct a clinical trial of the diabetes drug Liraglutide, giving it to patients with MND to see whether they improve or not. (2017-03-10)

Oral delivery system could make vaccination needle-free
Patients could one day self-administer vaccines using a needleless, pill-sized technology that jet-releases a stream of vaccine inside the mouth, according to a proof-of-concept study conducted at UC Berkeley. (2017-03-08)

FSU researchers take big step forward in nanotech-based drugs
In an article published today in Scientific Reports, FSU Associate Professor of Biological Science Steven Lenhert takes a step forward in the understanding of nanoparticles and how they can best be used to deliver drugs. (2017-03-08)

Penn researchers push the limits of organic synthesis
Penn researchers achieved a new understanding of dendritic molecules which could play a role in drug and gene delivery and antimicrobial resistance. (2017-03-07)

Nanozymes -- efficient antidote against pesticides
Members of the Faculty of Chemistry of the Lomonosov Moscow State University have developed novel nanosized agents -- nanozymes, which could be used as efficient protective and antidote modalities against the impact of neurotoxic organophosphorous compounds: pesticides and chemical warfare agents. (2017-03-07)

How molecular machines may drive the future of disease detection and drug delivery
In a study published in Nature Communications, University of Alberta researchers describe the creation of synthetic DNA motors in living cells. The process demonstrates how DNA motors can be used to accomplish specific and focused biological functions in live cells. The team believes the findings could lead to improved disease detection and drug delivery. (2017-03-06)

Vesicle formation findings could pave way for liquid biopsies, drug delivery devices
Engineers at Carnegie Mellon University and biomedical researchers at the University of Pittsburgh and Magee-Womens Research Institute have established a framework for understanding the mechanics that underlie vesicle formation. Their findings can be used to help develop liquid biopsies for a range of diseases and to develop new drug delivery vehicles. (2017-03-06)

Medicaid payment reform linked to fewer early elective deliveries
It's well documented that infants born at full term have better health outcomes. However, one in ten babies in the United States are born via a medically unnecessary early elective delivery, such as an induction of labor, cesarean section, or both. New findings published in Health Affairs indicate that state-level Medicaid payment reform is linked to fewer unnecessary early deliveries and, in turn, better health outcomes for infants. (2017-03-06)

Precise technique tracks dopamine in the brain
MIT researchers have devised a way to measure dopamine in the brain much more precisely than previously possible, which should allow scientists to gain insight into dopamine's roles in learning, memory, and emotion. (2017-03-03)

JAX receives NIH grant to improve CRISPR-Cas9 accuracy
A two-year grant totaling $455,000 from the National Institutes of Health to Michael V. Wiles, Ph.D., senior director of Technology Evaluation and Development at The Jackson Laboratory, will support research to improve the accuracy and efficiency of CRISPR-Cas9 genome editing for research, drug testing and future therapeutic delivery. (2017-03-01)

UTA student senior design project yields patent on smart bandage
Two faculty advisers -- engineering professors Panos Shiakolas and Pranesh Aswath -- supervised a student team, led by Letia Blanco, about five years ago in designing and building a smart bandage, which allowed more efficient healing of wounds and delivery of multiple drugs on their own time schedules to the wound, she wasn't sure what would become of it. (2017-03-01)

Inhaler users get about half as much medicine as they should from each puff
Tens of millions of Americans use aerosol inhalers each day, and new studies by Rice University electrical engineers and pulmonologists from Baylor College of Medicine have identified critical errors that are causing many inhaler users to get only about half as much medicine as they should from each puff. (2017-02-28)

Hitgen and Cancer Research UK's Manchester Institute enter license agreement in lung cancer
Cancer Research UK, Cancer Research Technology (CRT), the charity's commercial arm, and HitGen Ltd, a privately held biotech company focused on early drug discovery, announced today that they have entered into a licence agreement to develop a novel class of drugs against lung cancer. (2017-02-27)

3-D-printed bioabsorbable scaffold for ACL reconstruction with bone regeneration
Researchers have designed a 3-D-printed porous scaffold for use in reconstructing ruptured anterior cruciate ligaments (ACL) in the knee and engineered it to deliver a human bone-promoting protein over an extended period of time to improve bone regeneration. (2017-02-27)

Study says drugs could be developed cheaper and faster
Chemists at the University of Waterloo, SCIEX and Pfizer have discovered a new way to help the pharmaceutical industry identify and test new drugs, which could revolutionize drug development, and substantially reduce the cost and time drugs need to reach their market. (2017-02-22)

Precise inactivation of neural messenger receptor wipes out fear memory in mice
A neurotransmitter receptor was inactivated at synapses of the mouse hippocampus using a light-induced method of protein knockdown with enhanced specificity. Researchers incorporated an antibody against the outer region of the GluA1 receptor to inactivate the surface receptor with no damage to neighboring proteins. Mice injected with the antibody combined with a light-sensitive molecule received green light irradiation at the hippocampus, and demonstrated the loss of fear memory acquired in response to a fear-learning task. (2017-02-22)

Study finds testosterone replacement therapy reduces cardiovascular risk
Men who used testosterone replacement therapy to treat symptoms of androgen deficiency had a 33 percent lower risk of cardiovascular events such as heart attacks and stroke compared to those who did not receive any hormone therapy. The findings from the Kaiser Permanente study were published in JAMA Internal Medicine today. (2017-02-21)

DNA computer brings 'intelligent drugs' a step closer
Researchers at Eindhoven University of Technology present a new method that should enable controlled drug delivery into the bloodstream using DNA computers. Led by biomedical engineer Maarten Merkx the team developed the first DNA computer capable of detecting several antibodies in the blood and performing subsequent calculations based on this input. This is an important step towards the development of smart, 'intelligent' drugs that may allow better control of medication with fewer side-effects and at lower cost. (2017-02-17)

Nanotechnology based gene editing to eradicate HIV brain reservoir in drug abusers
The study will use nanotechnology with magneto electric nanoparticles (MENPs) to deliver drugs across the blood brain barrier in conjunction with the Cas9/gRNA gene editing strategy that has shown great promise in finding and destroying copies of HIV that have burrowed into the host's genome. (2017-02-15)

Dual-drug combination shows promise against diabetic eye disease in animal model
A two-drug cocktail provided better protection against diabetes-related vision loss than a single drug during testing in rat models, a team of University of Florida Health and Dutch researchers has found. (2017-02-15)

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