Current Drug Overdose News and Events

Current Drug Overdose News and Events, Drug Overdose News Articles.
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West Virginia's enduring, intertwined epidemics: Opioids and HIV
In a paper for The Lancet, West Virginia University Drs. Sally Hodder and Judith Feinberg state that the opioid and HIV epidemics are intertwined in West Virginia, and therefore should be treated together. (2021-02-22)

IU study finds unintended consequences of state, opioid policies
Study reveals the unintended and negative consequences of policies designed to reduce the supply of opioids in the population for overdose. (2021-02-17)

Drinking, smoking, and drug use linked to premature heart disease in the young
Recreational drinking, smoking, and drug use is linked to premature heart disease in young people, particularly younger women, finds research published online in the journal Heart. (2021-02-15)

Misuse of opioid drugs during pregnancy could have lasting impact on child's development
Researchers at the University of Maryland School of Medicine now have preliminary but striking evidence that suggests that such exposure can cause long-lasting impairment in the brain's ability to process sensory information. These impairments may give rise to autism, attention deficit hyperactivity disorder, and substance use disorders during adolescence. The landmark study was recently published in Journal of Neuroscience. (2021-02-11)

Death by suicide? Drug overdoses muddy waters for investigators, amplify mental health crisis
A new West Virginia University-led injury mortality study combines most drug overdose deaths with all suicides into an expanded self-injury category. Exposing a mental health crisis that has unraveled across the United States over the past two decades, study data have direct implications for suicide prevention efforts. (2021-02-08)

Experimental vaccine blunts the deadliest of synthetic opioids
As the opioid epidemic raged on with an even greater force during COVID-19, the Scripps Research laboratory of chemist Kim Janda, PhD, has been working on new therapeutic interventions that may be able to prevent the bulk of deaths from opioid overdose. Janda and his team have developed experimental vaccines that have shown in rodents to blunt the deadly effects of fentanyl as well as its even more fatal cousin, carfentanil. (2021-02-04)

New study examines addiction medicine treatment in Vietnam
A study published in The Lancet HIV marks one of the first scientifically robust assessments of a new model of treating HIV in lower or middle income countries where injection drug use is a major cause of HIV infection. It also suggests the importance of building support for peer and community connections to tackle the opioid epidemic that continues to ravage the United States in the midst of the COVID-19 pandemic. (2021-02-04)

BU researchers identify promising therapeutic agent against melanoma
There have been great advances in treating melanoma over the past five years, however, even with these treatments many patients quickly develop drug resistance and die from their disease. A new study from Boston University School of Medicine (BUSM) has discovered that a drug (YK-4-279) that was previously created to target one specific type of protein has much broader use against a family of proteins that act to promote melanoma. (2021-02-01)

Post-overdose outreach programs in Massachusetts expanding
Boston Medical Center has released a study that shows post overdose outreach programs in Massachusetts have expanded across the state, as 44 percent of municipalities reported having such programs available - a majority established since 2015 - to reduce risks for those who survive an overdose. (2021-01-28)

Counties with more cannabis dispensaries show reduced opioid deaths
This is the first study to examine the association between active cannabis dispensary operations -- both medical and recreational -- and opioid-related mortality rates at the county level, suggesting that providing alternative pain management could improve public health outcomes, researchers said. (2021-01-28)

Legal cannabis stores linked to fewer opioid deaths in the United States
Access to legal cannabis stores is associated with a reduction in opioid related deaths in the United States, particularly those linked to synthetic opioids such as fentanyl, finds a study published by The BMJ today. (2021-01-27)

Gut microbiota reveals whether drug therapies work in inflammatory bowel diseases
A study recently completed at the University of Helsinki indicates that the gut microbiota of patients suffering from inflammatory gastrointestinal disorders can be used to predict whether they will benefit from expensive therapies. The study also confirms the key role of therapies that have a beneficial effect on the gut microbiota in inflammatory bowel diseases. (2021-01-26)

University of Cincinnati research unveils possible new combo therapy for head and neck cancer
Researchers at the University of Cincinnati have tested a new combination therapy in animal models to see if they could find a way to make an already effective treatment even better. Since they're using a Food and Drug Administration-approved drug to do it, this could help people sooner than later. (2021-01-22)

Opiate overdoses spike in black Philadelphians, but drop in white residents since COVID-19
New research into opioid overdoses that occurred during the COVID-19 pandemic highlighted new disparities along racial lines that are likely fueled by existing inequality (2021-01-21)

Modified pain management strategy reduces opioid exposure to trauma patients, study shows
A pain management regimen comprised mostly of over-the-counter medication reduced opioid exposure in trauma patients while achieving equal levels of pain control, according to a new study by physician-researchers at UTHealth. (2021-01-21)

Methamphetamine overdose deaths rise sharply nationwide
Methamphetamine overdose deaths surged in an eight-year period in the United States, according to a study published today in JAMA Psychiatry. The analysis revealed rapid rises across all racial and ethnic groups, but American Indians and Alaska Natives had the highest death rates overall. The research was conducted at the National Institute on Drug Abuse (NIDA), part of the National Institutes of Health. (2021-01-20)

Youths with mood disorders who use marijuana at higher risk of death, self-harm
Youths with mood disorders who use and abuse cannabis (marijuana) have a higher risk for self-harm, death by all causes and death by unintentional overdose and homicide, according to research led by The Ohio State University Wexner Medical Center and The Ohio State University College of Medicine. (2021-01-19)

The link between opioid medication and pancreatic cancer
Using Center for Disease Control's national population health and cancer statistics datasets, Rush University Medical Center researchers determined that a state's opioid death rate significantly predicted the trend in the incidence of pancreatic cancer years later. This is the first study showing opioid use may be a risk factor contributing to the increasing incidence of pancreatic cancer (2021-01-06)

UC researcher urges caution using remdesivir to treat COVID-19
Research at the University of Cincinnati, however, contends that this antiviral drug is being used too indiscriminately when treating patients hospitalized with the virus. The study is published in the journal Fundamental & Clinical Pharmacology. (2020-12-29)

Study shows significant sex, age differences for nonfatal opioid overdoses in youth
Results of a national study show significant sex and age-based differences among youth and young adults who experience a nonfatal opioid overdose. (2020-12-22)

Recommendations for the overdose epidemic in the COVID-19 pandemic
A new report from researchers at the Johns Hopkins Bloomberg School of Public Health offers recommendations aimed at federal, state, and local policymakers to address the opioid epidemic during the pandemic. (2020-12-21)

Cannabis could reduce fentanyl use, reduce overdose risk: Study
New research suggests that cannabis use by people in care for opioid addiction might improve their treatment outcomes and reduce their risk of being exposed to fentanyl in the contaminated unregulated drug supply. (2020-12-18)

Researchers identify predictors of timely enrollment in treatment for opioid use disorder
Frequent doctor visits were associated with timely treatment, while prior overdose, alcohol use disorder and back problems predicted non-enrollment, study finds. (2020-12-16)

Experimental vaccine can counter dangerous effects of synthetic cannabinoids
Made in clandestine laboratories and sold widely across the United States, the diverse class of drugs known as synthetic cannabinoids presents a growing public health threat. In a new study, Scripps Research scientists have devised a way to deactivate these designer drugs after they've been administered--offering a potential path for treating addiction and overdose. (2020-12-16)

Overdose-related cardiac arrests observed by emergency medical services during COVID-19 pandemic
Emerging changes in overdose-related cardiac arrests in the U.S. during the COVID-19 pandemic are described in this observational study using a large national emergency medical services database. (2020-12-03)

Tarantula toxin attacks with molecular stinger
A bird-catching Chinese tarantula bite contains a stinger-like poison that plunges into a molecular target in the electrical signaling system of their prey's nerve cells. New cryo-electron microscopy studies show how this venom traps the voltage sensors of sodium channels in a resting state so they can't be activated. Such research may suggest designs for better drugs for chronic pain. (2020-11-23)

Study: Opioid overdose deaths involving other substances more common in youth
Results of a new study show that opioid overdose deaths involving more than one substance (polysubstances) are more common than opioid-only overdose deaths among youth. Led by researchers at Boston Medical Center's Grayken Center for Addiction, the data shows that cocaine and other stimulants like crystal methamphetamine are the substances most commonly involved in opioid overdose deaths in young people between the ages of 13 and 25. (2020-11-23)

Limited access to buprenorphine restricts resident physicians treating opioid abusers
A University of South Florida Health-led survey of resident physicians in Florida indicates they are interested in treating opioid addiction but face barriers to offering patients treatment using buprenorphine, an FDA-approved medication shown to successfully decrease opioid use, overdose events, and deaths associated with opioids. Many states have reported increased deaths from opioids since the COVID-19 epidemic began, underscoring the need to remove barriers to care. (2020-11-20)

UTSA researcher examines drug overdose mortality in the Hispanic community
UTSA researcher Manuel Cano, assistant professor in the Department of Social Work at UTSA is shedding light to understand the topic of drug overdose deaths in the Hispanic community. In the article ''Drug Overdose Deaths Among US Hispanics: Trends (2000-2017) and Recent Patterns'' published in ''Substance Use & Misuse'' Cano used national death certificate data (data recording all deaths of U.S. residents) to examine drug overdose mortality in different Hispanic subgroups, based on heritage, place of birth and gender. (2020-11-18)

Approved JAK inhibitor baricitinib shows promise against cytokine storm in COVID-19 clinical study
A clinical study involving 601 patients in Italy and Spain suggests that the JAK inhibitor drug baricitinib may enhance survival rates of patients (2020-11-13)

Calls to city 311 lines can predict opioid overdose hotspots
Service requests to city non-emergency telephone lines can help identify 'hotspots' for opioid use and overdoses, a study in Columbus found. Researchers found that calls to the 311 line - used in many cities across the United States to report non-emergency issues - tracked closely to places and times in Columbus in which opioid overdose events were on the rise. (2020-11-11)

'Diseases of despair' have soared over past decade in US
'Diseases of despair', such as substance abuse, alcohol dependency, and suicidal thoughts and behaviours, have soared in the US over the past decade, reveals an analysis of health insurance claims data published in the online journal BMJ Open. (2020-11-09)

Paracetamol poisonings up
In 2003, the painkiller paracetamol became available in Switzerland in tablets with a higher dose of the active ingredient. This correlates with an increase in cases of paracetamol poisoning in the country, as a data analysis by ETH researchers shows. (2020-10-28)

Computer vision helps find binding sites in drug targets
Scientists from the iMolecule group at Skoltech developed BiteNet, a machine learning (ML) algorithm that helps find drug binding sites, i.e. potential drug targets, in proteins. BiteNet can analyze 1,000 protein structures in 1.5 minutes and find optimal spots for drug molecules to attach. (2020-10-27)

New blood cancer treatment works by selectively interfering with cancer cell signalling
University of Alberta scientists have identified the mechanism of action behind a new type of precision cancer drug for blood cancers that is set for human trials, according to research published in Nature Communications. (2020-10-22)

New drug that can prevent the drug resistance and adverse effects
A research team in Korea is garnering attention for having developed an anticancer drug that could potentially prevent drug resistance. The Korea Institute of Science and Technology (KIST) announced that a team of researchers led by Dr. Kwang-meyung Kim at the Theragnosis research center successfully developed a cancer-specific anticancer drug precursor that can prevent the drug resistance. (2020-10-21)

Vitamin D: Consumption of high-dose food supplements is unnecessary
The German Federal Institute for Risk Assessment (BfR) has prepared a health risk assessment for products sold on the market as food supplements containing a daily dose of chole-calciferol -- the precursor to active vitamin D -- of 50 or 100 micrograms. These products are representative of certain high-dose preparations used by some consumers to increase their intake of vitamin D. (2020-10-20)

Cannabis use appears to encourage, not replace, non-medical opioid use
Contrary to some claims, people in the US may not be substituting cannabis for opioids, New research at Columbia examined the direction and strength of association between cannabis and opioid use among adults who used non-medical opioids. The findings showed that opioid use was at least as prevalent on days when cannabis was used as on days when it was not. The study is among the first to test opioid substitution directly. (2020-10-08)

Stopping opioid-related addiction, harm and accidents after surgery
An international group of global experts including anaesthetists, surgeons and other healthcare professionals have come together to publish a consensus statement on the prevention of opioid-related harm in adult surgical patients. The consensus statement is published in Anaesthesia (a journal of the Association of Anaesthetists). (2020-10-07)

Promising treatment for aggressive childhood cancer
A drug has shown great promise in the treatment of neuroblastoma, an aggressive form of childhood cancer. The study was led by researchers at Lund University in Sweden, and is published in the journal Science Translational Medicine. (2020-10-06)

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