Current Embryonic Development News and Events | Page 25

Current Embryonic Development News and Events, Embryonic Development News Articles.
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Tiny piece of RNA keeps 'clock' running in earliest stages of life
New research shows that a tiny piece of RNA has an essential role in ensuring that embryonic tissue segments form properly. (2013-03-11)

Biological tooth replacement -- a step closer
Scientists have developed a new method of replacing missing teeth with a bioengineered material generated from a person's own gum cells. Current implant-based methods of whole tooth replacement fail to reproduce a natural root structure and, as a consequence of the friction from eating and other jaw movement, loss of jaw bone can occur around the implant. (2013-03-08)

Swine cells could power artificial liver
Scientists are examining a line of (2013-02-27)

Sweet news for stem cell's 'Holy Grail'
Scientists have used sugar-coated scaffolding to move a step closer to the routine use of stem cells in the clinic and unlock their huge potential to cure diseases from Alzheimer's to diabetes. (2013-02-26)

Cell therapy a little more concrete thanks to VIB research
VIB scientists associated to the UGent have developed a mouse model that can advance the research on iPS cells to the next step. (2013-02-21)

IBN creates unlimited source of human kidney cells
Researchers at the Institute of Bioengineering and Nanotechnology have successfully generated human kidney cells from human embryonic stem cells in vitro1. Specifically, they produced the renal cells under artificial conditions in the lab without using animals or organs. This has not been possible until now. (2013-02-21)

The brainless origin of our head
A study by researchers from the Sars Centre in Bergen (Norway) and Ulrich Technau from the Deptartment of Molecular Evolution and Development (University Vienna) has shed new light on the evolutionary origin of the head. In a study published in the journal PLoS Biology they show that in a simple, brainless sea anemone, the same genes that control head development in higher animals regulate the development of the front end of the swimming larvae. (2013-02-20)

'Activating' RNA takes DNA on a loop through time and space
Long segments of RNA -- encoded in our DNA but not translated into protein -- are key to physically manipulating DNA in order to activate certain genes, say Wistar researchers. These non-coding RNA-activator molecules help create a loop of DNA to open up genes for transcription. They have a crucial role in turning genes on and off during early embryonic development, and have also been connected with genetic diseases, such as FG syndrome, and cancer. (2013-02-17)

Discovering cell surface proteins' behavior
A Simon Fraser University chemist is the lead author on a new paper that advances scientific understanding of the structure and function of glycoproteins, in particular the number and positioning of sugars on them. PLOS ONE, an international, peer-reviewed, open-access, online, scientific research journal, has just published the paper, N-glycoproteome of E14.Tg2a Mouse Embryonic Stem Cells. Glycoproteins are membrane proteins and are often involved in human diseases. They facilitate communication between cells. (2013-02-12)

Stem cell breakthrough could lead to new bone repair therapies on nanoscale surfaces
Scientists at the University of Southampton have created a new method to generate bone cells which could lead to revolutionary bone repair therapies for people with bone fractures or those who need hip replacement surgery due to osteoporosis and osteoarthritis. (2013-02-11)

Protein paves the way for correct stem cell differentiation
A single embryonic stem cell can develop into more than 200 specialized cell types that make up our body. This maturation process is called differentiation and is tightly regulated. Research from BRIC, University of Copenhagen, has identified a crucial role of the molecule Fbxl10 in differentiation of embryonic stem cells and suggests the molecule as a new potential target for cancer therapy. (2013-02-07)

Cells forged from human skin show promise in treating MS, myelin disorders
A study out today in the journal Cell Stem Cell shows that human brain cells created by reprogramming skin cells are highly effective in treating myelin disorders, a family of diseases that includes multiple sclerosis and rare childhood disorders called pediatric leukodystrophies. (2013-02-07)

Key protein revealed as trigger for stem cell development
A natural trigger that enables stem cells to become any cell type in the body has been discovered by scientists. Researchers have identified a protein that kick-starts the process by which stem cells can develop to into different cells in the body, for instance liver or brain cells. (2013-02-07)

Paired genes in stem cells shed new light on gene organization and regulation
Research from Whitehead Institute shows that transcription at the active promoters of protein-coding genes commonly runs in opposite directions. This leads to coordinated production of both protein-coding messenger RNAs and long noncoding RNAs. (2013-02-04)

3D printing breakthrough with human embryonic stem cells
A team of researchers from Scotland has used a novel 3D printing technique to arrange human embryonic stem cells for the very first time. (2013-02-04)

International team observe 'hungry twin' stars gobbling their first meals
Years of monitoring its infrared with the Spitzer instrument reveal that it becomes 10 times brighter every 25.34 days, Gutermuth and colleagues say. This periodicity suggests that a companion to the central forming star is likely inhibiting the infall of gas and dust until its closest orbital approach, when matter eventually comes crashing down onto the protostellar (2013-01-31)

Joslin scientists find first human iPSC from patients with maturity onset diabetes of the young
Scientists at Joslin Diabetes Center in Boston report the first generation of human induced pluripotent stem cells from patients with an uncommon form of diabetes, maturity onset diabetes of the young (MODY). These cells offer a powerful resource for studying the role of genetic factors in the development of MODY and testing potential treatments. (2013-01-31)

Epigenetic control of cardiogenesis
Scientists from the Max Planck Institute for Molecular Genetics in Berlin, in collaboration with colleagues at MIT and the Broad Institute in Boston, have now been able to demonstrate that non-coding RNA is essential for normal embryonic cardiogenesis. (2013-01-29)

Patients' own skin cells are transformed into heart cells to create 'disease in a dish'
In a paper published Jan. 27 in Nature, researchers at Sanford-Burnham Medical Research Institute and Johns Hopkins University unveil the first maturation-based (2013-01-27)

Monitoring and robust induction of nephrogenic intermediate mesoderm from human iPSCs
The research group led by Associate Professor Kenji Osafune and his colleague Shin-ichi Mae has succeeded in developing a highly efficient method of inducing human induced pluripotent stem cells to differentiate into intermediate mesoderm, the precursor of kidney, gonad, and other cell lineages. This represents a major step toward realizing renal regeneration. (2013-01-25)

BUSM study shows potential of differentiated iPS cells in cell therapy without immune rejection
A new study from Boston University School of Medicine shows that tissues derived from induced pluripotent stem (iPS) cells in an experimental model were not rejected when transplanted back into genetically identical recipients. (2013-01-25)

Chance finding reveals new control on blood vessels in developing brain
Zhen Huang freely admits he was not interested in blood vessels four years ago when he was studying brain development in a fetal mouse. Instead, he wanted to see how changing a particular gene in brain cells called glia would affect the growth of neurons. The result was hemorrhage, caused by deteriorating veins and arteries, and it begged for explanation. (2013-01-24)

Retrovirus in the human genome is active in pluripotent stem cells
A retrovirus called HERV-H, which inserted itself into the human genome millions of years ago, may play an important role in pluripotent stem cells. The discovery, which may help explain how these cells maintain a state of pluripotency and are able to differentiate into many types of cells, could have profound implications for therapies that would use pluripotent stem cells to treat a range of human diseases. (2013-01-23)

Stem cell research helps to identify origins of schizophrenia
New University at Buffalo research demonstrates how defects in an important neurological pathway in early development may be responsible for the onset of schizophrenia later in life. (2013-01-22)

New insights into how leprosy infection spreads could pave the way for early intervention
A new study, published by Cell Press Jan. 17 in the journal Cell, reveals that the bacteria responsible for leprosy spread infection by hijacking specialized cells in the adult nervous system, reprogramming them into a stem cell-like state, and converting them to muscle-like cells. These findings could lead to the development of new therapeutic strategies for combating bacterial infections and degenerative diseases as well as new tools for regenerative medicine. (2013-01-17)

Lack of protein Sp2 disrupts neuron creation in brain
A protein known as Sp2 is key to the proper creation of neurons from stem cells, according to researchers at North Carolina State University. (2013-01-15)

Protein identified that can disrupt embryonic brain development and neuron migration
New research by Dr. Eve Seuntjens and Dr. Veronique van den Berghe of the Department of Development and Regeneration at KU Leuven has identified two proteins, Sip1 and Unc5b, that play an important role in the development and migration of interneurons to the cerebral cortex -- a breakthrough in our understanding of early brain development. (2013-01-14)

Researchers use iPSCs to define optimal treatment for managing life-threatening arrhythmias
Researchers used induced pluripotent stem cells derived from a young patient with Long QT syndrome (LQTS), a congenital heart disorder, to determine a course of treatment that helped manage the patient's life-threatening arrhythmias. The results, which appear in The Journal of General Physiology, could lead to improved treatments for LQTS and other channelopathies, diseases caused by disturbed ion channel function. (2013-01-11)

Stem cells found to heal damaged artery in lab study
Scientists at the Texas Biomedical Research Institute in San Antonio have for the first time demonstrated that baboon embryonic stem cells can be programmed to completely restore a severely damaged artery. These early results show promise for eventually developing stem cell therapies to restore human tissues or organs damaged by age or disease. (2013-01-10)

Baby sharks stay still to avoid being detected by predators
Baby sharks still developing in their egg cases can sense when predators are near, and keep very still to avoid being detected, according to research published January 9 in the open access journal PLOS ONE by Ryan Kempster from the University of Western Australia and colleagues. (2013-01-09)

Stem cell materials could boost research into key diseases
Stem cell manufacturing for drug screening and treatments for diseases such as Huntington's and Parkinson's could be boosted by a new method of generating stem cells, a study suggests. Scientists have developed a family of compounds that can support the growth of human embryonic stem cells on a large scale for use in drug testing or treatments. (2013-01-08)

Sorting stem cells
Scientists propose a new way to isolate early stage embryonic stem cells. (2013-01-03)

GW professor discovers new information in the understanding of autism and genetics
Research out of the George Washington University School of Medicine and Health Sciences, published in the journal Proceedings of the National Academy of Sciences, reveals another piece of the puzzle in a genetic developmental disorder that causes behavioral diseases such as autism. (2013-01-03)

Protein kinase Akt identified as arbiter of cancer stem cell fate
The protein kinase Akt is a key regulator of cell growth, proliferation, metabolism, survival, and death. New research shows that Akt may be the key as to why cancer stem cells are so hard for the body to get rid of. (2012-12-20)

Sync to grow
Researchers at EMBL are one step closer to understanding how embryos develop and grow while always keeping the same proportions between their various parts. Their findings, published today in Nature, reveal that scaling of the future vertebrae in a mouse embryo is controlled by how the expression of some specific genes oscillates, in a coordinated way, between neighboring cells. (2012-12-20)

Celldance 2012 video awards, the 'Cell Oscars,' roll out tiny red carpet
A microscopic-scale (2012-12-17)

Ordinary heart cells become 'biological pacemakers' with injection of a single gene
Cedars-Sinai Heart Institute researchers have reprogrammed ordinary heart cells to become exact replicas of highly specialized pacemaker cells by injecting a single gene -- a major step forward in the decade-long search for a biological therapy to correct erratic and failing heartbeats. (2012-12-16)

UCLA stem cell researchers receive more than $6 million in grants from state agency
Two cardiology investigators from the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at UCLA have been awarded grants totaling more than $6 million from the California Institute of Regenerative Medicine, the state's stem cell agency. (2012-12-14)

Congenital heart defects could have their origin during very early pregnancy
The origins of congenital heart defects could be traced right back to the first stages of embryonic development - according to University of East Anglia research. Findings published today in the journal PLOS ONE show that the beginnings of important parts of the heart can be traced to very early stages of embryo development. (2012-12-13)

From fish to man: Research reveals how fins became legs
Vertebrates' transition to living on land, instead of only in water, represented a major event in the history of life. Now, researchers reporting in the December issue of the Cell Press journal Developmental Cell provide new evidence that the development of hands and feet occurred through the gain of new DNA elements that activate particular genes. (2012-12-10)

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