Current Emphysema News and Events

Current Emphysema News and Events, Emphysema News Articles.
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Heavier smoking linked to skyrocketing health risks
Each cigarette smoked a day by heavier smokers increases the risk of contracting some diseases by more than 30 per cent, according to a new international study published today. (2020-08-07)

Lung-specific risk factors may increase hip fracture risk in individuals who smoke
Smoking has been linked to a higher risk of bone fractures. Researchers have now identified certain lung-related factors that may help to predict an individual smoker's fracture risk. The findings are published in the Journal of Bone and Mineral Research. (2020-08-05)

A targeted treatment for emphysema?
Emphysema is a progressive, debilitating lung disease in which the lung's breathing sacs, or alveoli, enlarge, get thinner, and eventually are destroyed as the cells die off. It can be fatal, and there is currently no cure. New research at Boston Children's Hospital, using lung cells and mouse models of emphysema, offers hope in the form of a small, engineered peptide molecule called PR1P. (2020-08-04)

Artificial intelligence could serve as backup to radiologists' eyes
Deploying artificial intelligence could help radiologists to more accurately classify lung diseases. (2020-04-27)

COPD linked to heightened risk of lung cancer in people who have never smoked
COPD, short for chronic obstructive pulmonary disease, is linked to a heightened risk of lung cancer in people who have never smoked, indicates research published online in the journal Thorax. (2020-04-02)

UK study highlights importance of spirometry in diagnosing COPD
A UK study of patients participating in low-dose CT lung cancer screening highlights the importance of spirometry (breathing tests) in the assessment of possible chronic obstructive pulmonary disease (COPD), and demonstrates that over-reliance on radiological changes alone may result in detection of clinically insignificant disease. The new study is published online in the Annals of the American Thoracic Society. (2020-03-13)

Evidence linking 'vaping' to increased odds of asthma and COPD
Using data from a large federal government telephone survey of adults, Johns Hopkins Medicine researchers report evidence that inhaling heated tobacco vapor through e-cigarettes was linked to increased odds of asthma and chronic obstructive pulmonary disease (COPD), conditions long demonstrated to be caused by smoking traditional, combustible cigarettes. (2020-01-07)

New diagnostic criteria proposed for chronic obstructive pulmonary disease (COPD)
More than 100 of the nation's leading pulmonologists have proposed new criteria for diagnosing chronic obstructive pulmonary disease. The new criteria could better capture the full spectrum of people suffering from COPD, lead to better care for patients, and stimulate research to slow or stop progression of the disease or even prevent it. The proposal expands diagnostic criteria from a single measure of lung function to include environmental exposure, symptoms, and abnormal CT scans. (2019-11-12)

E-cigs can trigger same lung changes seen in smokers, emphysema
In a study published in the American Journal of Respiratory and Critical Care Medicine, the UNC scientists found that the lungs of vapers -- like the lungs of smokers -- have elevated levels of protease enzymes, a condition known to cause emphysema in smokers. The researchers also found that the nicotine in vaping liquids is responsible for the increase in protease enzymes. (2019-08-22)

Study finds link between long-term exposure to air pollution and emphysema
Long-term exposure to air pollution was linked to increases in emphysema between 2000 and 2018, according to a new study funded by the National Institute of Environmental Health Sciences (NIEHS) and the National Heart, Lung, and Blood Institute (NHLBI), both part of the National Institutes of Health. (2019-08-13)

Exposure to outdoor air pollutants, change in emphysema, lung function
Whether exposure to outdoor air pollutants is associated with emphysema progression and change in lung function was the focus of this observational study. The study included 7,071 participants from the Multi-Ethnic Study of Atherosclerosis studies conducted in six US metropolitan regions (New York; Los Angeles; Chicago; Baltimore; Winston-Salem, N.C.; and St. Paul, Minn.). Computed tomographic (CT) scans were used to assess changes in emphysema (measured for density as a percentage of lung pixels) and lung function testing was done. (2019-08-13)

Air pollution can accelerate lung disease as much as a pack a day of cigarettes
Air pollution -- especially ozone air pollution which is increasing with climate change -- accelerates the progression of emphysema of the lung, according to a new study led by the University of Washington, Columbia University and the University at Buffalo. (2019-08-13)

Pollutant linked to climate change accelerates lung disease
A new multicenter study at Columbia University links long-term exposure to air pollution, especially ozone, to development of emphysema, accelerating lung disease progression as much as a pack a day of cigarettes. (2019-08-13)

Good physical fitness in middle age linked to lower chronic lung disease risk
Good heart and lung (cardiorespiratory) fitness in middle age is associated with a lower long term risk of chronic lung disease (COPD), suggests Danish research published online in the journal Thorax. (2019-06-18)

Electronic inhaler monitoring reduces hospitalizations, ER visits in patients with COPD
In one of the first-of-its-kind studies, Cleveland Clinic researchers found that the use of electronic inhaler monitoring, in combination with a disease management program, is associated with reduced healthcare utilization in patients with chronic obstructive pulmonary disease (COPD). The paper was published May 16, 2019 in the Journal of Telemedicine and Telecare. (2019-06-11)

Steroids can reduce lung cancer risk in COPD patients
For many people with chronic obstructive pulmonary disease or COPD, a steroid inhaler is a daily necessity to keep their airways open and help them to breathe. Now, a new UBC analysis shows that these medicated devices may also reduce patients' risk of lung cancer by as much as 30 per cent. (2019-05-28)

Piedmont Atlanta first in Georgia to offer new minimally invasive treatment for emphysema
Piedmont Atlanta Hospital is the first in the state of Georgia to offer a new minimally invasive treatment for emphysema, a severe form of Chronic Obstructive Pulmonary Disease (COPD). (2019-05-23)

MedStar Franklin Square to offer new treatment option for qualified emphysema patients
MedStar Franklin Square is the first medical facility in the state to offer endoscopic lung volume reduction (ELVR), using a new FDA-approved lung valve that is positioned in damaged lung airways without surgery, and allows patients with severe emphysema to breathe easier. (2019-05-20)

Australian research uncovers link between dietary fiber and lung disease
Dietary fiber may be a new tool in the prevention of progressive lung disease, thanks to the production of anti-inflammatory short chain fatty acids (SCFA), according to a new study by Australia's Priority Research Centre for Healthy Lungs at University of Newcastle, and the Centre for Inflammation, a partnership between the University of Technology Sydney and Centenary Institute. (2019-04-04)

More needs to be done to raise awareness of lung cancer risk in people with COPD
People with chronic obstructive pulmonary disease (COPD) need more support when understanding and acting on new chest symptoms, a study in the journal Psycho-Oncology reports. (2019-02-18)

Researchers breathe new life into COPD research using mouse models
Tokyo Medical and Dental University (TMDU) researchers revealed that the immune cells basophils caused emphysema in mice with COPD-like features induced by intranasal administration of elastase. They showed that basophils, previously linked mainly to allergies and fighting parasites, initiated a cascade of reactions eventually leading to the release of excess MMP-12 and the destruction of alveolar walls. The team hopes that the findings will lead to breakthroughs in the treatment of COPD. (2019-01-31)

National Institute for Health and Care Excellence (NICE) issues new guidelines for COPD
NICE makes a 'strong' recommendation that patients with severe COPD be referred for evaluation for bronchoscopic lung volume reduction, including the Zephyr® Endobronchial Valve System. NICE has broadened the criteria for evaluation and a new group of people for whom lung volume reduction surgery was unsuitable may now be evaluated for treatment with Zephyr Valves, a less invasive treatment option. (2018-12-11)

Protein may slow progression of emphysema, Rutgers study finds
A protein generated as part of our body's immune response to intestinal worms could slow the progression of emphysema, according to a Rutgers study. (2018-12-04)

Temple Lung Center director reports ongoing positive results for emphysema treatment study
Dr. Gerard Criner, MD, FACP, FACCP, Chair and Professor of Thoracic Medicine and Surgery at the Lewis Katz School of Medicine at Temple University, announced the 12-month results of the EMPROVE multicenter, randomized and controlled study for the Spiration® Valve System (SVS), a minimally invasive treatment for severe emphysema, at the European Respiratory Society International Congress (ERS) in Paris, France, on Sept. 18. (2018-10-02)

Kidney disease biomarker may also be a marker for COPD
A commonly used biomarker of kidney disease may also indicate lung problems, particularly COPD, or chronic obstructive pulmonary disease, according to new research published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. (2018-09-28)

Dental research shows that smoking weakens immune systems
Researchers at the Case Western Reserve University School of Dental Medicine found that smoking weakens the ability for pulp in teeth to fight illness and disease. (2018-09-26)

Stem cell therapy drug may protect against smoke-related COPD symptoms
A drug used in stem cell therapy to treat certain cancers may also protect against cigarette smoke-induced lung injury. The study, published ahead of print in the American Journal of Physiology--Lung Cellular and Molecular Physiology, was chosen as an APSselect article for July. (2018-07-05)

Quitting smoking, but not cutting back, linked to better lung health
Long-term light smokers appear to be at greater risk for lung function decline, emphysema and obstructive lung disease than heavy smokers who quit, according to new research presented at the ATS 2018 International Conference. (2018-05-22)

Temple-led trial demonstrates effectiveness of minimally invasive emphysema treatment
Surgically removing small portions of damaged lung tissue helps some patients with severe emphysema, but is invasive and risky. Now, an effective, but safer option -- the Zephyr® Endobronchial Valve (Zephyr® EBV®), an endoscopic lung volume reduction therapy manufactured by Pulmonx Corporation -- may provide an alternative. In LIBERATE, a Temple-led clinical trial, implantation of Zephyr® EBV® successfully reduced shortness of breath and improved lung function and quality of life, with benefits lasting at least one-year post-intervention. (2018-05-22)

Formidable duo: Protective effect of CD9 and CD81 in COPD and accelerated aging
Chronic obstructive pulmonary disease (COPD) is a disease of accelerated lung aging, but the mechanism remains unclear. Osaka University-centered researchers studied the aging-like phenotype and its underlying mechanisms in a COPD mouse model. Double deletion of tetraspanins CD9 and CD81 in epithelial cells downregulated expression of the protein SIRT. As SIRT1 is a key molecule that protects against various lifestyle-related diseases and aging, these tetraspanins may serve as novel therapeutic targets for COPD and aging (2018-04-16)

Accurate telomere length test influences treatment decisions for certain diseases
Research led by Johns Hopkins physicians and scientists shows that a test for measuring the length of DNA endcaps, called telomeres, which has a variability rate of 5 percent, can alter treatment decisions for patients with certain types of bone marrow failure. (2018-02-26)

Defect in zinc supply mechanism affects pathology of intractable pulmonary diseases
Japanese researchers revealed that abnormal delivery of zinc to lung cells contributes to obstructive pulmonary diseases. They further showed that mRNA splicing abnormalities are involved in the detailed mechanism. So far, the importance of zinc in the lung has only been understood from a nutritional aspect. This discovery is thought to be the first to clarify zinc's effects on the regulation of mRNA ligation (splicing), and its involvement in the onset of pulmonary diseases. (2017-12-28)

Study shows lower lung cancer rates in communities with strong smoke-free laws
Researchers at the University of Kentucky studied the correlation between communities with strong smoke-free workplace laws and the number of new lung cancer diagnoses. Those communities have 8% fewer new cases than communities with weak or no workplace laws. (2017-11-29)

Locally administered compound offers prolonged relief from airway constriction
Scientists have identified a compound that triggered long-lasting airway relaxation and prevented hyperreactivity in mouse models of asthma, potentially paving the way to a new therapeutic target for multiple breathing disorders. (2017-09-13)

Therapy proves effective in subgroup of COPD patients
Antibody treatment reduces rate of flare-ups in patients with a subgroup of treatment-resistant COPD. (2017-09-12)

Endobronchial valve treatment appears to improve lung function in patients with severe emphysema
People with severe emphysema may breathe better after a minimally invasive procedure that places valves in the airways leading to diseased portions of their lungs, according to a randomized, controlled trial published online in the American Thoracic Society's American Journal of Respiratory and Critical Care Medicine. (2017-09-08)

3-D organoids and RNA sequencing reveal the crosstalk driving lung cell formation
To investigate lung-cell formation, researchers used a 3-D 'organoid' culture system allowing them to observe what kinds of cells were being made. To this, they added single-cell RNA sequencing to see what genes each cell type turns on, which enabled them to identify what the cells are saying to each other. As reported today in Cell, they found that lung cells known as mesenchymal cells are the cells driving the action. (2017-09-07)

Artificial intelligence predicts patient lifespans
A computer's ability to predict a patient's lifespan simply by looking at images of their organs is a step closer to becoming a reality, thanks to new research led by the University of Adelaide. (2017-06-01)

Quit-smoking drug safe for patients with lung disease, study finds
Medication that helps smokers to quit is safe for use by people with chronic lung conditions, research led by the Universities of Edinburgh and Dusseldorf suggests. (2017-05-10)

Trial of new triple inhaler shows 20 percent reduction in COPD flare-ups
Flare-ups in chronic obstructive pulmonary disease, the UK's fourth leading cause of death, can be reduced by 20 percent by a combined triple inhaler, according to the results of a trial of more than 2,000 people conducted by the University of Manchester. (2017-04-03)

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