Current Epilepsy News and Events

Current Epilepsy News and Events, Epilepsy News Articles.
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Deep brain stimulation prevents epileptic seizures in mouse model
Scientists led by neurobiologist Prof. Dr. Carola Haas, head of the research group at the Department of Neurosurgery at Medical Center - University of Freiburg and the BrainLinks-BrainTools research center, have investigated a new therapeutic approach to prevent epileptic seizures in temporal lobe epilepsy. They showed in mice that low-frequency stimulation of specific brain areas could completely stop epileptic activity. (2021-02-19)

Tailor-made drugs to treat epilepsy or cardiovascular diseases
In order for a drug to be effective at the right places in the body, it helps if scientists can predict as accurately as possible how the molecules of that drug will interact with human cells. In a joint research project, scientists from Leipzig University and the Chinese Academy of Sciences in Shanghai have succeeded in elucidating such a structure, namely that of the neuropeptide Y receptor Y2 with one of its ligands. (2021-02-10)

'Sleep hygiene' should be integrated into epilepsy diagnosis and management - study
Children with epilepsy sleep poorly compared to healthy children, and are more likely to experience disruptions such as night terrors, sleep walking or sleep disordered breathing, according to a new study. (2021-02-10)

New research studies 'domino effects' and synchrony in brain activity
Scientists have made a significant breakthrough in the quest to understand the intricate processes that occur in the brain during seizures that are the key symptom of epilepsy. (2021-02-05)

Accurate drug dosages with proton traps
Researchers at Linköping University, Sweden, have developed a proton trap that makes organic electronic ion pumps more precise when delivering drugs. The new technique may reduce drug side effects, and in the long term, ion pumps may help patients with symptoms of neurological diseases for which effective treatments are not available. The results have been published in Science Advances. (2021-01-29)

Rare genetic syndrome identified, caused by mutations in gene SATB1
Variations in the gene SATB1 have been shown to cause a rare genetic syndrome. Different variations across the gene lead to varied effects on the cell, leading to a difference in the severity of neurodevelopmental disorders. Discovery of this genetic syndrome is hoped to provide information to families and individuals affected by SATB1-syndrome. (2021-01-28)

A new mechanism protects against cancer cell migration and neuron hyperexcitability
G3BP proteins inhibit the metabolic driver MTOR - a signaling protein that plays a central role in tumor diseases and developmental disorders of the brain. This is reported in this week´s issue of the renowned journal Cell. The study was led by scientists from the University of Innsbruck and the German Cancer Research Center (DKFZ) in collaboration with the Medical University of Innsbruck and a Europe-wide research network. (2021-01-25)

Protein anchors as a newly discovered key molecule in cancer spread and epilepsy
Certain anchor proteins inhibit a key metabolic driver that plays an important role in cancer and developmental brain disorders. Scientists from the German Cancer Research Center (DKFZ) and the University of Innsbruck, together with a Europe-wide research network, discovered this molecular mechanism, which could open up new opportunities for personalized therapies for cancer and neuronal diseases. They published their results in the journal Cell. (2021-01-25)

Epilepsy research focused on astrocytes
A significant number of epilepsy patients does not respond to currently available drugs. A collaboration between researchers in Japan and at the Heinrich Heine University Düsseldorf (HHU) now addressed a cell type in the brain that has so far not received much attention in epilepsy therapy. In the current edition of the Journal of Neuroscience, they describe that astrocytes might be a potential new target to better treat this disease. (2021-01-25)

Domino effects and synchrony in seizure initiation
In a brain with a neurological disorder like epilepsy, synchronization between groups of neurons can grow to a dangerous extent when a collection of brain cells begins to emit excess electricity. Researchers used a mathematical model to explore the interplay between neurons that leads to these transitions in synchronization during the onset of seizures. (2021-01-25)

Intelligence deficit: Conclusion from the mouse to the human being
Impaired intelligence, movement disorders and developmental delays are typical for a group of rare diseases that belong to GPI anchor deficiencies. Researchers now used genetic engineering methods to create a mouse that mimics these patients very well. Studies in this animal model suggest that in GPI anchor deficiencies, a gene mutation impairs the transmission of stimuli at the synapses in the brain. The results are published in the journal PNAS. (2021-01-07)

Functional seizures associated with stroke, psychiatric disorders in EHR study
In a large-scale study of electronic health records reported in JAMA Network Open, Vanderbilt University Medical Center investigators determined the prevalence of functional seizures and characterized comorbidities associated with them. Functional seizures are sudden attacks or spasms that look like epileptic seizures but do not have the aberrant brain electrical patterns of epilepsy. The research team confirmed associations between functional seizures and psychiatric disorders and sexual assault trauma and discovered a novel association with stroke. (2021-01-07)

Neurology patients faced with rising out-of-pocket costs for tests, office visits
Just like with drug costs, the amount of money people pay out-of-pocket for diagnostic tests and office visits for neurologic conditions has risen over 15 years, according to a new study published in the December 23, 2020, online issue of issue of Neurology®, the medical journal of the American Academy of Neurology. (2020-12-23)

Researchers explore why some MS patients experience seizures
A research team at the UC Riverside School of Medicine has identified a pathway involving astrocytes, a class of central nervous system support cells, that could shed light on why seizures happen in a subset of multiple sclerosis, or MS, patients. The finding improves scientific understanding of how seizures arise in MS and could provide the foundation for better therapies to manage treatment-resistant seizures in MS and other brain diseases. (2020-12-21)

A weather station for epileptic seizure
The onset of epileptic seizures is unpredictable. Neuroscientists from the University of Geneva, the University Hospital of Bern and the University of California in San Francisco, have succeeded in developing a technique that can predict seizures between one and several days in advance. By recording neuronal activity over at least six months using a device implanted directly in the brain, it is possible to provide information about the probability of a future seizure. (2020-12-18)

Seizure risk forecasted days in advance with brain implant data
Patterns of brain activity can be used to forecast seizure risk in epilepsy patients several days in advance, according to a new analysis of data obtained from clinically approved brain implants by neuroscientists at UC San Francisco, the University of Bern, and the University of Geneva. (2020-12-17)

Researchers reveal how our brains know when something's different
NIH scientists discovered how a set of high frequency brain waves may help us unconsciously know when something's different by comparing memories of the past with present experiences. (2020-12-14)

Predicting epilepsy from neural network models
A new study published in EPJ B shows how 'tipping points' in the brain, responsible for diseases including epilepsy, can be better predicted by accounting for branches in networks of neurons. (2020-12-08)

Big data analysis suggests role of brain connectivity in epilepsy-related atrophy
An international study has found a link between the brain's network connections and grey matter atrophy caused by certain types of epilepsy, a major step forward in our understanding of the disease. (2020-12-02)

Doctors report unusual case of patient 'mirror writing' in the emergency room
In new research presented at Euroanaesthesia (the annual meeting of the European Society of Anaesthesiology and Intensive Care [ESAIC]), doctors report a highly unusual case of a right-handed patient performing unconscious 'mirror-writing' with her left hand while in the midst of having epileptic seizures in the emergency room. (2020-11-27)

Worms reveal why melatonin promotes sleep
Melatonin is used as a dietary supplement to promote sleep and get over jet lag, but nobody really understands how it works in the brain. Now, researchers at UConn Health show that melatonin helps worms sleep, too, and they suspect they've identified what it does in us. (2020-11-13)

Mathematical modeling of processes in neurons to assist the treatment of epilepsy and depression
Researchers study the effect of neural stimulation by ultrasonic waves and analyzing the influence of ultrasonic wave parameters on the excitation of electrical signals in the nerves. The obtained results have a great practical value for further studies related to the issues of human brain modeling. (2020-11-02)

Antiseizure medication in pregnancy associated with twice the risk of autism in child
Women with epilepsy who take the antiseizure drug valproic acid while pregnant are at more than double the risk of having children with autism spectrum disorder and nearly double the risk of having children with attention deficit hyperactivity disorder (ADHD), according to a study in the October 28, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology. (2020-10-28)

Focal epilepsy often overlooked
Having subtler symptoms, a form of epilepsy that affects only one part of the brain often goes undiagnosed long enough to cause unexpected seizures that contribute to car crashes, a new study finds. (2020-10-20)

College of Medicine researcher makes novel discoveries in preventing epileptic seizures
A team of researchers from the Florida State University College of Medicine has found that an amino acid produced by the brain could play a crucial role in preventing a type of epileptic seizure. (2020-10-13)

Inhibiting epileptic activity in the brain
A new study shows that a protein -- called DUSP4 -- was increased in healthy brain tissue directly adjacent to epileptic tissue. The research suggests that boosting levels of DUSP4 could be a novel way of preventing or treating epilepsy. (2020-10-08)

Study identifies brain cells most affected by epilepsy and new targets for their treatment
Researchers from the University of Copenhagen have identified new potential drug targets for treatment of epilepsy. In the largest single cell dataset for a brain disease published so far, researchers pinpoint the neurons of the human brain which are most affected by epilepsy. (2020-10-07)

Obstructive sleep apnea risk varies in patients with different types of epilepsy
People with generalized epilepsy who have seizures arising from both sides of the brain simultaneously, have a higher risk of obstructive sleep apnea (OSA) compared to patients who have focal epilepsy where seizures emanate from one area of the brain, according to a Rutgers study. (2020-09-29)

Is the "Mozart Effect" real? New analysis indicates that music can help epilepsy
A new comprehensive analysis on the effect of Mozart's music on epilepsy has confirmed that listening to his piano music can reduce the frequency of epilepsy attacks. The results of this comprehensive meta-analysis (a study of studies), which may overturn current scepticism about the effect, are presented at the ECNP congress after recent publication in a peer-reviewed journal (2020-09-11)

Monitoring sleep positions for a healthy rest
MIT researchers have developed a wireless, private way to monitor a person's sleep postures -- whether snoozing on their back, stomach, or sides -- using reflected radio signals from a small device mounted on a bedroom wall. (2020-09-10)

Using magnetic resonance elastography to detect epilepsy
A new study from the Beckman Institute used magnetic resonance elastography to compare the hippocampal stiffness in healthy individuals with those who have epilepsy. (2020-09-02)

Brain protein linked to seizures, abnormal social behaviors
A team led by a biomedical scientist at the University of California, Riverside has found a new mechanism responsible for the abnormal development of neuronal connections in the mouse brain that leads to seizures and abnormal social behaviors. (2020-08-31)

New era in brain monitoring technology
Subscalp brain monitoring devices could offer long-term, continuous, and reliable recording of neural activity at home and in the clinic. (2020-08-27)

Seizures during menstrual cycle linked to drug-resistant epilepsy
More frequent seizures during the menstrual cycle in women with genetic generalized epilepsy have been linked for the first time to drug-resistant epilepsy, when anti-seizure medications don't work, according to a Rutgers coauthored study that may help lead to tailored treatments. (2020-08-26)

Genetic causes of severe childhood brain disorders found using new computational methods
A team of researchers have combined clinical information with large-scale genomic data to successfully link characteristic presentations of childhood epilepsies with specific genetic variants. (2020-08-26)

Investigational new therapy prevents onset of Dravet syndrome symptoms in mice
In a development that may finally offer hope to children with Dravet syndrome and their parents, a promising investigational new therapeutic appears to alter the destructive course of the deadly disease in a mouse model. (2020-08-26)

Combining genetic information with EMRs to pinpoint childhood epilepsies
A team of researchers further bridged the gap between genomic information and clinical outcome data by systematically linking genetic information with electronic medical records, focusing on how genetic neurological disorders in children develop over time. (2020-08-11)

Blood test could diagnose baby brain damage just hours after birth
An early blood test could detect which babies deprived of oxygen at birth are at risk of serious neurodisabilities like cerebral palsy and epilepsy. (2020-08-04)

Epilepsy: International researchers propose better seizure classification
A new ''mathematical language'' to classify seizures in epilepsy could lead to more effective clinical practice, researchers from Europe, the US, Australia and Japan propose in a new publication in eLife. An epilepsy model developed by the Human Brain Project provides the basis for the novel framework, which could also push forward basic understanding of the disease. (2020-07-31)

Pandemic to accelerate adoption of electronic patient portal for epilepsy
The COVID-19 pandemic is a catalyst to accelerate the adoption of technology-enabled patient care for epilepsy, according to a new study published in Epilepsia. (2020-07-24)

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