Current Epileptic Seizures News and Events

Current Epileptic Seizures News and Events, Epileptic Seizures News Articles.
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Deep brain stimulation prevents epileptic seizures in mouse model
Scientists led by neurobiologist Prof. Dr. Carola Haas, head of the research group at the Department of Neurosurgery at Medical Center - University of Freiburg and the BrainLinks-BrainTools research center, have investigated a new therapeutic approach to prevent epileptic seizures in temporal lobe epilepsy. They showed in mice that low-frequency stimulation of specific brain areas could completely stop epileptic activity. (2021-02-19)

Risk factors associated with COVID-19 ICU admission or death in Argentina
A nationwide analysis of data from the first 6 months of the COVID-19 pandemic in Argentina has identified factors associated with increased risk of death or admission to an intensive care unit (ICU) due to the disease, including older age, male sex, coma, seizures, and underlying comorbidities. Daniel Schoenfeld of Centro Diagnostico San Jorge in Puerto Madryn, Argentina, and colleagues present these findings in the open-access journal PLOS ONE on February 11. (2021-02-11)

'Sleep hygiene' should be integrated into epilepsy diagnosis and management - study
Children with epilepsy sleep poorly compared to healthy children, and are more likely to experience disruptions such as night terrors, sleep walking or sleep disordered breathing, according to a new study. (2021-02-10)

New research studies 'domino effects' and synchrony in brain activity
Scientists have made a significant breakthrough in the quest to understand the intricate processes that occur in the brain during seizures that are the key symptom of epilepsy. (2021-02-05)

Unraveling the mystery of Gao, a protein implicated in movement disorders
Scientists at Scripps Research have clarified the workings of a mysterious protein called Gao, which is one of the most abundant proteins in the brain and, when mutated, causes severe movement disorders. (2021-02-02)

Epilepsy research focused on astrocytes
A significant number of epilepsy patients does not respond to currently available drugs. A collaboration between researchers in Japan and at the Heinrich Heine University Düsseldorf (HHU) now addressed a cell type in the brain that has so far not received much attention in epilepsy therapy. In the current edition of the Journal of Neuroscience, they describe that astrocytes might be a potential new target to better treat this disease. (2021-01-25)

Domino effects and synchrony in seizure initiation
In a brain with a neurological disorder like epilepsy, synchronization between groups of neurons can grow to a dangerous extent when a collection of brain cells begins to emit excess electricity. Researchers used a mathematical model to explore the interplay between neurons that leads to these transitions in synchronization during the onset of seizures. (2021-01-25)

Elusive link between seizures, cell signaling protein ID'd in zebrafish
A team of Virginia Tech scientists led by Yuchin Albert Pan, an associate professor at the Fralin Biomedical Research Institute at VTC, have identified a new link between seizures and connexin 36 deficiency. The discovery, published Jan. 11 in Frontiers in Molecular Neuroscience, found that this interaction may make the brain more prone to having seizures. (2021-01-11)

Functional seizures associated with stroke, psychiatric disorders in EHR study
In a large-scale study of electronic health records reported in JAMA Network Open, Vanderbilt University Medical Center investigators determined the prevalence of functional seizures and characterized comorbidities associated with them. Functional seizures are sudden attacks or spasms that look like epileptic seizures but do not have the aberrant brain electrical patterns of epilepsy. The research team confirmed associations between functional seizures and psychiatric disorders and sexual assault trauma and discovered a novel association with stroke. (2021-01-07)

Eavesdropping on the pH levels inside the brain
Researchers at Tohoku University have developed the first all-in-one miniature pH probe for real-time investigations of intrinsic extracellular pH dynamics in the deep brain structures. (2020-12-23)

Researchers explore why some MS patients experience seizures
A research team at the UC Riverside School of Medicine has identified a pathway involving astrocytes, a class of central nervous system support cells, that could shed light on why seizures happen in a subset of multiple sclerosis, or MS, patients. The finding improves scientific understanding of how seizures arise in MS and could provide the foundation for better therapies to manage treatment-resistant seizures in MS and other brain diseases. (2020-12-21)

A weather station for epileptic seizure
The onset of epileptic seizures is unpredictable. Neuroscientists from the University of Geneva, the University Hospital of Bern and the University of California in San Francisco, have succeeded in developing a technique that can predict seizures between one and several days in advance. By recording neuronal activity over at least six months using a device implanted directly in the brain, it is possible to provide information about the probability of a future seizure. (2020-12-18)

Seizure risk forecasted days in advance with brain implant data
Patterns of brain activity can be used to forecast seizure risk in epilepsy patients several days in advance, according to a new analysis of data obtained from clinically approved brain implants by neuroscientists at UC San Francisco, the University of Bern, and the University of Geneva. (2020-12-17)

COVID-19 may also invade the central nervous system, cause neurological illnesses
COVID-19 is known primarily as a respiratory disease, with symptoms that include cough, shortness of breath, and, in severe cases, acute respiratory distress syndrome and pneumonia. Now, Cleveland Clinic researchers note in a recent review that infection with the coronavirus may also affect the central nervous system and cause corresponding neurological disorders, including ischemic stroke, encephalitis, encephalopathy and epileptic seizures. According to the review published in Cells, the symptoms of COVID-19-related neurological manifestations include dizziness, headache, a loss of consciousness and ataxia. (2020-12-10)

New guidelines for treating the complications of brain tumours
Experts from the leading oncology societies ESMO (European Society for Medical Oncology) and EANO (European Association of Neuro-Oncology) hav now compiled international guidelines and standards for the treatment of complications of brain tumours (2020-12-09)

Predicting epilepsy from neural network models
A new study published in EPJ B shows how 'tipping points' in the brain, responsible for diseases including epilepsy, can be better predicted by accounting for branches in networks of neurons. (2020-12-08)

A role for the slow oscillations of the neocortex in epileptic spasm generation
Epileptic spasms are a type of brief seizures that are the hallmark of catastrophic seizure disorders and characterized by severe cognitive and motor deficits. Researchers from Baylor College of Medicine and Texas Children's Hospital have found the source and mechanism to explain how cortical neurons generate spasms. This is also the first study to reveal a hitherto unknown relationship between a normal brain state, like sleep, and spasms. (2020-12-08)

Doctors report unusual case of patient 'mirror writing' in the emergency room
In new research presented at Euroanaesthesia (the annual meeting of the European Society of Anaesthesiology and Intensive Care [ESAIC]), doctors report a highly unusual case of a right-handed patient performing unconscious 'mirror-writing' with her left hand while in the midst of having epileptic seizures in the emergency room. (2020-11-27)

Venous origin of brain blood-vessel malformations
In the condition known as cavernoma, lesions arise in a cluster of blood vessels in the brain, spinal cord or retina. Researchers from Uppsala University can now show, at molecular level, that these changes originate in vein cells. This new knowledge of the condition creates potential for developing better therapies for patients. The study has been published in the journal eLife. (2020-11-03)

Study reveals unexpected protective role for brain swelling after injury
Following a brain-injuring bump or blow to the head, brain cells and blood vessels typically swell. This can lead to a potentially life-threatening increase in pressure inside the skull, and managing swelling is critical for patients with traumatic brain injuries (TBIs). But researchers at University of Utah Health have discovered that swelling may also be important for protecting the brain. (2020-11-02)

Novel method for measuring spatial dependencies turns less data into more data
Researcher makes 'little data' act big through, the application of mathematical techniques normally used for time-series, to spatial processes. The study, 'An information-theoretic approach to study spatial dependencies in small datasets,' featured on the cover of Proceedings of the Royal Society. (2020-10-21)

Focal epilepsy often overlooked
Having subtler symptoms, a form of epilepsy that affects only one part of the brain often goes undiagnosed long enough to cause unexpected seizures that contribute to car crashes, a new study finds. (2020-10-20)

College of Medicine researcher makes novel discoveries in preventing epileptic seizures
A team of researchers from the Florida State University College of Medicine has found that an amino acid produced by the brain could play a crucial role in preventing a type of epileptic seizure. (2020-10-13)

Nerve cell activity shows how confident we are
Should I or shouldn't I? The activity of individual nerve cells in the brain tells us how confident we are in our decisions. This is shown by a recent study by researchers at the University of Bonn. The result is unexpected - the researchers were actually on the trail of a completely different evaluation mechanism. The results are published in the journal Current Biology. (2020-10-09)

Inhibiting epileptic activity in the brain
A new study shows that a protein -- called DUSP4 -- was increased in healthy brain tissue directly adjacent to epileptic tissue. The research suggests that boosting levels of DUSP4 could be a novel way of preventing or treating epilepsy. (2020-10-08)

Study identifies brain cells most affected by epilepsy and new targets for their treatment
Researchers from the University of Copenhagen have identified new potential drug targets for treatment of epilepsy. In the largest single cell dataset for a brain disease published so far, researchers pinpoint the neurons of the human brain which are most affected by epilepsy. (2020-10-07)

Obstructive sleep apnea risk varies in patients with different types of epilepsy
People with generalized epilepsy who have seizures arising from both sides of the brain simultaneously, have a higher risk of obstructive sleep apnea (OSA) compared to patients who have focal epilepsy where seizures emanate from one area of the brain, according to a Rutgers study. (2020-09-29)

Potent drug supply drop, not domestic drug policies, likely behind 2018 OD death downturn
The slight decline in drug overdose deaths in 2018 coincides with Chinese regulations on the powerful opioid carfentanil, rather than the result of domestic U.S. efforts to curb the epidemic, a new analysis reveals. What many - including President Donald Trump - perceived as a decline in overdose deaths in 2018, appears to be a return to the historic exponential curve. (2020-09-16)

Is the "Mozart Effect" real? New analysis indicates that music can help epilepsy
A new comprehensive analysis on the effect of Mozart's music on epilepsy has confirmed that listening to his piano music can reduce the frequency of epilepsy attacks. The results of this comprehensive meta-analysis (a study of studies), which may overturn current scepticism about the effect, are presented at the ECNP congress after recent publication in a peer-reviewed journal (2020-09-11)

Scientists discover key regulator of neuron function and survival
Scientists studying neuronal energy metabolism found evidence the loss of an important energy regulator called AMPK in neural stem cells or glial cells called astrocytes causes neuronal death in laboratory rodents. Publishing their findings in Cell Reports, researchers also discovered AMPK loss in neural stem cells or neurons causes spontaneous brain seizures in the animals. The study provides evidence that a medication used to treat diabetes may help control epileptic seizures. (2020-09-01)

Tel Aviv University study sheds light on brain mechanism activated by uncertainty
A new Tel Aviv University study examined the brain's reactions in conditions of uncertainty and stressful conflict in an environment of risks and opportunities. The researchers identified the areas of the brain responsible for the delicate balance between desiring gain and avoiding loss along the way. (2020-09-01)

New era in brain monitoring technology
Subscalp brain monitoring devices could offer long-term, continuous, and reliable recording of neural activity at home and in the clinic. (2020-08-27)

Seizures during menstrual cycle linked to drug-resistant epilepsy
More frequent seizures during the menstrual cycle in women with genetic generalized epilepsy have been linked for the first time to drug-resistant epilepsy, when anti-seizure medications don't work, according to a Rutgers coauthored study that may help lead to tailored treatments. (2020-08-26)

Genetic causes of severe childhood brain disorders found using new computational methods
A team of researchers have combined clinical information with large-scale genomic data to successfully link characteristic presentations of childhood epilepsies with specific genetic variants. (2020-08-26)

Investigational new therapy prevents onset of Dravet syndrome symptoms in mice
In a development that may finally offer hope to children with Dravet syndrome and their parents, a promising investigational new therapeutic appears to alter the destructive course of the deadly disease in a mouse model. (2020-08-26)

Combining genetic information with EMRs to pinpoint childhood epilepsies
A team of researchers further bridged the gap between genomic information and clinical outcome data by systematically linking genetic information with electronic medical records, focusing on how genetic neurological disorders in children develop over time. (2020-08-11)

Epilepsy: International researchers propose better seizure classification
A new ''mathematical language'' to classify seizures in epilepsy could lead to more effective clinical practice, researchers from Europe, the US, Australia and Japan propose in a new publication in eLife. An epilepsy model developed by the Human Brain Project provides the basis for the novel framework, which could also push forward basic understanding of the disease. (2020-07-31)

Molecular cause underlying rare genetic disorder revealed
Scientists identify how a nonfunctioning CASK gene creates chaos in the brain. (2020-07-27)

Calcium channel subunits play a major role in autistic disorders
Neurobiologists at Johannes Gutenberg University Mainz (JGU) in Germany have found new evidence that specific calcium channel subunits play a crucial role in the development of excitatory and inhibitory synapses. (2020-07-22)

New vitamin K-based drug shows promise against medication-resistant epilepsy
Medical University of South Carolina researchers have designed a new vitamin K-based compound that shows excellent seizure-control properties, even in preclinical models of medication-resistant seizures. Over 1 million people in the US suffer from medication-resistant epilepsy, contending with poor quality of life due to unpredictable seizures. This vitamin K analog, with its unique structure and low toxicity, could one day be a boon for patients whose seizures are not controlled by standard medications. (2020-07-06)

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