Current Epithelial Cells News and Events

Current Epithelial Cells News and Events, Epithelial Cells News Articles.
Sort By: Most Relevant | Most Viewed
Page 1 of 25 | 1000 Results
Kittens could hold key to understanding deadly diarrheal disease in children
Kittens could be the model for understanding infectious, sometimes deadly, diarrheal disease in both animals and children. (2021-02-23)

New insights on how inflammatory molecule contributes to skin and pancreatic cancers
An immune molecule called interleukin-33 can act within a cell's nucleus to stimulate abnormal growth and division, ultimately resulting in cancer. Targeting interleukin-33 in the nucleus may help prevent certain cancers. (2021-02-22)

Discovery of a mechanism by which epithelial tumours cause developmental delays
- Conducted on the fly Drosophila, the study shows that tumours caused by chromosomal instability delay entry into the adult phase. - The tumours produce the Upd3 protein (equivalent to human Interleukin-6) to block the production of developmental steroid hormones. - The work of IRB Barcelona's Growth Control and Development laboratory has been published in the journal Current Biology. (2021-02-22)

Oncotarget: MEK inhibitors relevant to SARS-CoV-2 infection
The @Oncotarget authors show a drug class-effect with MEKi to stimulate NK cells, inhibit inflammatory cytokines and block host-factors for SARS-CoV-2 infection leading also to suppression of SARS-CoV-2-S pseudovirus infection of human cells (2021-02-22)

Organoids grown from bile duct cells repair human livers; may aid liver transplant processes
Organoids grown from bile duct epithelial cells can be used to repair damaged bile ducts in transplanted human livers, researchers report. (2021-02-18)

Mount Sinai researchers identify mechanisms that are essential for proper skin development
Latest discovery could improve development of future stem cell therapies and cancer treatments. (2021-02-18)

Genotoxic E. coli 'caught in the act'
Max Planck researchers and their collaborators reveal transformation of colon organoids in vitro. (2021-02-17)

How the immune system paves the way for SARS-CoV-2
The immune system actually wants to fight SARS-CoV-2 with antiviral signaling molecules. But a research team from Charité and MDC has now shown how such a signaling molecule can promote the replication of the virus. The results have been published in the journal EMBO Molecular Medicine. (2021-02-16)

Cold sores: Discovery reveals how stress, illness and even sunburn trigger flareups
The finding could lead to new ways to prevent cold sores and herpes-related eye disease from reoccurring, the researchers report. (2021-02-11)

Earliest signs of an immune response found in developing embryos
Researchers at the Centre for Genomic Regulation reveal that newly formed embryos clear dying cells to maximise their chances of survival. It is the earliest display of an innate immune response found in vertebrate animals to date. The findings may aid future efforts to understand why some embryos fail to form in the earliest stages of development, and lead to new clinical efforts in treating infertility or early miscarriages. (2021-02-10)

A recipe for regenerating bioengineered hair
Scientists have recently developed ways to grow a variety of useful items in laboratories, from meat and diamonds to retinas and other organoids. At the RIKEN Center for Biosystems Dynamics Research in Japan, a team led by Takashi Tsuji has been working on ways to regenerate lost hair from stem cells. In an important step, a new study identifies a population of hair follicle stem cells in the skin and a recipe for normal cyclical regeneration in the lab. (2021-02-10)

Scientists uncover four new facts about early SARS-CoV-2 infections
University of Minnesota Medical School researchers studied SARS-CoV-2 infections at individual cellular levels and made four major discoveries about the virus, including one that validates the effectiveness of remdesivir - an FDA-approved antiviral drug - as a form of treatment for severe COVID-19 disease. (2021-02-10)

Phages can anticipate bacteria's location and destroy them before they cause an infection
A novel strategy has the potential of becoming a game changer in the fight against antibiotic-resistant bacteria that live in hard-to-reach places. (2021-02-09)

Identification of three genes that determine the stemness of gastric tissue stem cells
Tissue stem cells can self-renew and differentiate, supplying cells necessary for tissues at various developmental stages. However, detailed analysis in vivo is difficult, so the molecular mechanisms underlying the stemness of gastric tissue stem cells have remained a mystery. Here, by using organoids that mimic tissue structure and function in vivo and GeCKO screening to inactivate arbitrary genes, Alk, Bclaf3 and Prkra have been identified as genes regulating stemness. (2021-02-08)

Molecular sleuthing identifies and corrects major flaws in blood-brain barrier model
A type of cell derived from human stem cells that has been widely used for brain research and drug development may have been leading researchers astray for years, according to a study from scientists at Weill Cornell Medicine and Columbia University Irving Medical Center. (2021-02-08)

Critical flaw found in lab models of the human blood-brain barrier
Cells used to study the human blood-brain barrier in the lab aren't what they seem, a new study has found, throwing nearly a decade's worth of research into question. (2021-02-05)

Hypoxia, a feature inside solid cancer tumors, reprograms methylation of ribosomal RNAs
Hypoxia -- where a tissue is deprived of an adequate supply of oxygen -- is a feature inside solid cancer tumors that renders them highly invasive and resistant to treatment. Researchers now report that chronic hypoxia, surprisingly, upregulates RNA polymerase I activity and alters the methylation patterns on ribosomal RNAs. These altered epigenetic marks on the ribosomal RNAs appear to create a pool of specialized ribosomes that can differentially regulate translation of messenger RNA. (2021-02-03)

Stopping intestinal bacteria in their tracks
POSTECH Professor Seung-Woo Lee's research team identifies the mechanism behind the differentiation of intestinal epithelial lymphocytes. (2021-02-03)

Melatonin produced in the lungs prevents infection by novel coronavirus
The hormone acts as a barrier against SARS-CoV-2, blocking the expression of genes that encode proteins in cells serving as viral entry points, according to a study by researchers at the University of São Paulo. (2021-01-27)

'Tri-active' contraceptive gel combines spermicidal, anti-viral, libido-enhancing agents
Researchers have created a trifunctional contraceptive gel that contains spermicidal, anti-viral and libido-enhancing agents in one formulation. (2021-01-26)

Oncotarget: Drug-resistant cells grow exponentially in metastatic prostate cancer
The Oncotarget authors show that the drug-resistant, metastasis-causing cells are capable of producing drug-resistant, exponentially growing tumors, responsible for tumor growth as a patient receives different treatments (2021-01-25)

Novel molecules to combat asthma and covid-related lung diseases discovered
Australian researchers have made the extraordinary discovery of two molecules - one found in a commercially available dietary supplement - that provide profound protection in experimental models of asthma and can also substantially reduce the severity of asthma attacks. The molecules also appear to have a role in treating the respiratory illness that is often fatal in people with serious COVID-19. (2021-01-25)

Getting under your skin: Molecular research builds new understanding of skin regeneration
New research from Northwestern University has found new evidence deep within the skin about the mechanisms controlling skin repair and renewal. (2021-01-19)

A mathematical study describes how metastasis starts
A scientific study carried out by the Universidad Carlos III de Madrid (UC3M) and the Universidad Complutense de Madrid (UCM) has produced a mathematical description of the way in which a tumor invades the epithelial cells and automatically quantifies the progression of the tumor and the remaining cell islands after its progression. The model developed by these researchers could be used to better understand the biophysical characteristics of the cells involved when developing new treatments for wound healing, organ regeneration, or cancer progression. (2021-01-18)

A master cancer gene hijacks a 'molecular crowbar' to make breast cancer cells invasive
Researchers investigated how cancer genes lead to the breakdown of the capsule that prevents cancerous cells from invading the surrounding healthy tissues and - find a hijacked ''molecular crowbar''. The new findings help understand the mechanisms of cancer spreading and reveal a cancer vulnerability. (2021-01-18)

Novel organoid models: Illuminating path to cervical cancers
How do tumors develop in the cervix? Many new details are now known about this question. This is also thanks to Dr. Cindrilla Chumduri from the Biocentre at the University of Würzburg. (2021-01-18)

NIH scientists study salmonella swimming behavior as clues to infection
Salmonella enterica serovar Typhimurium bacteria (S. Typhimurium) commonly cause human gastroenteritis, inflammation of the lining of the intestines. The bacteria live inside the gut and can infect the epithelial cells that line its surface. Many studies have shown that Salmonella use a ''run-and-tumble'' method of short swimming periods (runs) punctuated by tumbles when they randomly change direction, but how they move within the gut is not well understood. (2021-01-13)

Scientists identify "immune cop" that detects SARS-CoV-2
Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified the sensor in human lungs that detects SARS-CoV-2 and signals that it's time to mount an antiviral response. (2021-01-12)

Oncotarget: PD-1/PD-L1 expression in anal squamous intraepithelial lesions
Dr. Margot Bucau from The Hôpital Bichat-Claude Bernard said, ''Anal intraepithelial neoplasia (AIN) is the precursor lesion for anal squamous cell carcinomas (ASCC). (2021-01-11)

Simple bioreactor makes 'gut check' more practical
Rice University and Baylor College of Medicine researchers develop lab tool to mimic conditions in intestines, giving them a mechanical model for the real-time growth of bacterial infections. (2021-01-07)

Tracking the formation of the early heart, cell by cell
Richard Tyser and colleagues have mapped the origins of the embryonic mouse heart at single-cell resolution, helping to define the cell types that make up the heart in the earliest days of development. (2021-01-07)

Study: e-cigarettes trigger inflammation in the gut
Chemicals used for vaping break down zipper-like junctions between cells in the gut, leading to chronic inflammation and potential for other health concerns. (2021-01-07)

Gut cells sound the alarm when parasites invade
When the parasite Cryptosporidium enters the body, it's cells in the intestines that first recognize the invader, triggering an early immune response, according to a new study led by a team from the University of Pennsylvania. A leading cause of diarrheal disease in young children globally, the parasite generates an inflammatory response beginning in the intestines that exacerbates the effects of malnutrition. (2020-12-28)

Protein tells developing cells to stick together
Tohoku University scientists have, for the first time, provided experimental evidence that cell stickiness helps them stay sorted within correct compartments during development. How tightly cells clump together, known as cell adhesion, appears to be enabled by a protein better known for its role in the immune system. The findings were detailed in the journal Nature Communications. (2020-12-24)

Brain stem cells divide over months
For the first time, scientists at the University of Zurich have been able to observe the way stem cells in the adult brains of mice divide over the course of months to create new nerve cells. Their study shows that brain stem cells are active over a long period, and thus provides new insights that will feed into stem cell research. (2020-12-21)

Loss of anti-tumor protein may cause resistance to certain cancer therapies
The absence of a protein that works to prevent tumor formation may explain why some patients are resistant to a common cancer therapy, according to Penn State College of Medicine researchers. They said that testing cancers for the presence of this protein may help clinicians identify patients who may be resistant to or relapse when treated with the therapy. (2020-12-21)

Three-dimensionally reconstituted organoids that are just like human organs
POSTECH-Seoul National University Hospital research team publishes the new concept of assembloids in Nature. (2020-12-18)

SARS-CoV-2 induces inflammation, cytokine storm and stress in infected lung cells
The researchers Wasco Wruck and Prof. James Adjaye from the Institute of Stem Cell Research and Regenerative Medicine, Medical Faculty of Heinrich-Heine-University Duesseldorf, Germany, employed a bioinformatic approach on transcriptome data pertaining to human lung epithelial cells infected with SARS-CoV-2. The meta-analysis unveiled several adversely affected biological processes in the lung which no doubt also applies to other infected organs such as the heart and kidney. Their study is published in Scientific Reports. (2020-12-18)

Cancer: Tumor driver promoting EMT, metastasis and resistance to therapy
Publication in Nature: researchers at the Université libre de Bruxelles (ULB) identify, for the first time, the functions of FAT1, one of the most frequently mutated cancer gene drivers. They uncover that FAT1 mutations promotes invasive features, metastasis and resistance to commonly used anti-cancer drugs, and discover new therapy for FAT1 mutated cancers. (2020-12-16)

Study shows endothelial cell targeting could help fight Covid-19 symptoms
For Covid-19 patients with serious lung disease, targeting endothelial cells -cells that comprise the blood vessel wall which regulate oxygen exchange between airways and the bloodstream- may be a novel approach restoring normal lung function. (2020-12-14)

Page 1 of 25 | 1000 Results
   First   Previous   Next      Last   
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.