Current Fat Cells News and Events

Current Fat Cells News and Events, Fat Cells News Articles.
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Fat cells may influence how the body reacts to heart failure, study shows
University of Alberta researchers have found that limiting the amount of fat the body releases into the bloodstream from fat cells when in heart failure could help improve outcomes for patients. (2021-02-23)

Low-quality maternal diet during pregnancy may be associated with late-childhood obesity
Eating a low quality diet, high in foods and food components associated with chronic inflammation, during pregnancy may be associated with an increased risk of obesity and excess body fat in children, especially during late-childhood. The findings are published the open access journal BMC Medicine. (2021-02-21)

Store fat or burn it? Targeting a single protein flips the switch
As obesity becomes a growing issue worldwide - nearly tripling over the last-half century - scientists are trying to gain a better understanding of the condition at the molecular level. Now, new research led by UC San Francisco scientists suggests that a single protein could play an outsize role in weight gain. (2021-02-18)

Phase I clinical trial shows promise of adipose-derived stem cells in treating lymphedema
Results of a phase I clinical trial released in STEM CELLS Translational Medicine shows there is a strong possibility that stem cells may alleviate lymphedema, a chronic debilitating condition affecting up to one in three women treated for breast cancer. (2021-02-17)

Body shape, beyond weight, drives fat stigma for women
Fat stigma in women contributes to poor medical outcomes and negatively affects educational and economic opportunities. A new study from scientists at Arizona State University and Oklahoma State University shows that body shape, beyond overall weight, drives fat stigma. Women with overweight and obesity who carry gluteofemoral fat were less stigmatized than those who carry abdominal fat. These findings could affect how interventions for overweight and obesity are designed and delivered. (2021-02-17)

Fatty tissue accumulated in the neck linked to heart problems, study finds
Researchers from the University of Granada warn that an accumulation of fatty tissue in the neck (both the double chin and the deeper deposits, located between muscles and around the cervical vertebrae) is a predictor of central and overall adiposity, cardiometabolic risk, and a pro-inflammatory profile in sedentary young adults (2021-02-17)

3D microscopy clarifies understanding of body's immune response to obesity
Researchers who focus on fat know that some adipose tissue is more prone to inflammation-related comorbidities than others, but the reasons why are not well understood. Thanks to a new analytical technique, scientists are getting a clearer view of the microenvironments found within adipose tissue associated with obesity. This advance may illuminate why some adipose tissues are more prone to inflammation - leading to diseases like type 2 diabetes, cancer and cardiovascular disorders - and help direct future drug therapies to treat obesity. (2021-02-17)

FSU College of Medicine researcher develops new possibilities to prevent sudden cardiac death
Stephen Chelko, an assistant professor of biomedical sciences at the Florida State University College of Medicine, has developed a better understanding of the pathological characteristics behind arrhythmogenic cardiomyopathy, as well as promising avenues for prevention. (2021-02-17)

Cytoglobin: key player in preventing liver disease
Researchers have discovered that the use of Cytoglobin (CYGB) as an intravenous drug could delay liver fibrosis progression in mice. CYGB, discovered in 2001 by Professor Norifumi Kawada, is present in hepatic stellate cells, the cells that produce fibrotic molecules such as collagens when the liver has acute or chronic inflammation induced by different etiologies. The enhancement of CYGB on these cells or the injection of recombinant CYGB has the effect of suppressing liver damage and cirrhosis. (2021-02-16)

Unlocking the mystery behind skeletal aging
Researchers from the UCLA School of Dentistry have identified the role a critical enzyme plays in skeletal aging and bone loss, putting them one step closer to understanding the complex biological mechanisms that lead to osteoporosis, the bone disease that afflicts some 200 million people worldwide. Findings, published online in the journal Cell Stem Cell, could hold an important key to developing more effective treatments for osteoporosis and improving the lives of an aging population. (2021-02-15)

Chinese people may be more susceptible to obesity-related health risks than other racial, ethnic groups
Chinese people are more likely to face high blood pressure and other health risks as a result of higher body mass index (BMI) and waist circumference than people from other racial and ethnic groups, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2021-02-11)

Monitoring the body's fat burning by breath
Your breath holds the key to monitoring fat burning, and now a research group from Tohoku University has created a compact and low-cost device that can measure how our body metabolizes fat. (2021-02-10)

More deaths in England and Scotland may be due to obesity and excess body fat than smoking
Obesity and excess body fat may have contributed to more deaths in England and Scotland than smoking since 2014, according to research published in the open access journal BMC Public Health. (2021-02-10)

Vegan diet better for weight loss and cholesterol control than Mediterranean diet
A vegan diet is more effective for weight loss than a Mediterranean diet, according to a groundbreaking new study that compared the diets head to head. The randomized crossover trial, which was published in the Journal of the American College of Nutrition, found that a low-fat vegan diet has better outcomes for weight, body composition, insulin sensitivity, and cholesterol levels, compared with a Mediterranean diet. (2021-02-05)

Study finds childhood diet has lifelong impact
Eating too much fat and sugar as a child can alter your microbiome for life, even if you later learn to eat healthier, a new UC Riverside study in mice suggests. (2021-02-03)

Two studies shed light on how, where body can add new fat cells
DALLAS - Feb. 3, 2021 - Gaining more fat cells is probably not what most people want, although that might be exactly what they need to fight off diabetes and other diseases. How and where the body can add fat cells has remained a mystery - but two new studies from UT Southwestern provide answers on the way this process works. (2021-02-03)

Senolysis by glutaminolysis inhibition ameliorates various age-associated disorders
A collaborative research group led by Professor Makoto Nakanishi of the Institute of Medical Science, The University of Tokyo (IMSUT) has identified an inhibitor of the glutamate metabolic enzyme GLS1 so that its administration selectively eliminates senescent cells in vivo. They confirmed that the GLS1 inhibitor eliminated senescent cells from various organs and tissues in aged mice, ameliorating age-associated tissue dysfunction and the symptoms of obese diabetes, arteriosclerosis, and NASH. The results of this research were published in 'Science' on January 15, 2021. (2021-02-03)

Body and mind: hormones in the brain may explain how exercise improves metabolism
A mitochondrial hormone expressed by cells deep in the brain appears to play a role in improving metabolism and fighting off obesity, according to a new study in mice. (2021-02-02)

Stem cell study illuminates the cause of a devastating inherited heart disorder
Penn Medicine scientists have uncovered the molecular causes of a congenital form of dilated cardiomyopathy (DCM)-- one of multiple congenital disorders caused by inherited mutations in a gene called LMNA. The scientists used stem cell techniques to grow human heart muscle cells containing DCM-causing mutations in LMNA. They found that these mutations severely disrupt the structural organization of DNA in the nucleus of heart muscle cells. (2021-02-01)

'Weak' and 'strong' cells bonding boosts body's diabetes fight
Scientists have broadened our understanding of how 'weak' cells bond with their more mature cellular counterparts to boost the body's production of insulin, improving our knowledge of the processes leading to type 2 diabetes - a significant global health problem. (2021-01-29)

How vitamins, steroids and potential antivirals might affect SARS-CoV-2
Evidence is emerging that vitamin D -- and possibly vitamins K and A -- might help combat COVID-19. A new study from the University of Bristol published in the journal of the German Chemical Society Angewandte Chemie has shown how they - and other antiviral drugs -- might work. The research indicates that these dietary supplements and compounds could bind to the viral spike protein and so might reduce SARS-CoV-2 infectivity. (2021-01-29)

How fat loss accelerates facial aging
For many of us, as we get older the skin on our face begins to sag and we seem to lose volume around our eyes, cheeks and chin. Is gravity taking its toll in our later years or do we lose fat over the course of several years that many of us associate with youth, vibrancy and energy? Understanding the cause is paramount to how plastic surgeons treat the signs of facial aging. (2021-01-27)

Scientists use a novel ink to 3D print 'bone' with living cells
3D printers may one day become a permanent fixture of the operating theatre after UNSW scientists showed they could print bone-like structures containing living cells. (2021-01-25)

A stem cell based cell culture model for nonalcoholic fatty liver disease
Nonalcoholic fatty liver disease (NAFLD) is a widespread condition in the Western World. In order to improve our understanding of the basic mechanisms underlying the etiology of NAFLD, Dr. Nina Graffmann, Prof. James Adjaye and the team of the Institute for Stem Cell research and Regenerative Medicine, University Hospital Duesseldorf, differentiated induced pluripotent stem cells (iPSCs) derived from healthy donors and NAFLD patients into hepatocyte-like cells (HLCs). (2021-01-25)

The liver processes coconut oil differently than rapeseed oil
Coconut oil has increasingly found its way into German kitchens in recent years, although its alleged health benefits are controversial. Scientists at the University of Bonn have now been able to show how it is metabolized in the liver. Their findings could also have implications for the treatment of certain diarrheal diseases. The results are published in the journal Molecular Metabolism. (2021-01-25)

New perspectives challenge the idea that saturated fats cause heart disease
Why do saturated fats increase blood cholesterol, and why should this be dangerous? After all, saturated fats occur naturally in a wide variety of foods, including breast milk. (2021-01-22)

Researchers study what happens to your body during tailgating
Football watch parties are synonymous with eating fatty foods and drinking alcohol. Have you ever wondered what all of that eating and drinking does to your body? Researchers from the University of Missouri School of Medicine simulated a tailgating situation with a small group of overweight but healthy men and examined the impact of the eating and drinking on their livers using blood tests and a liver scan. (2021-01-20)

Clumsy kids can be fit too
Clumsy kids can be as aerobically fit as their peers with better motor skills, a new Finnish study shows. The results are based on research conducted at the Faculty of Sport and Health Sciences of the University of Jyväskylä and the Institute of Biomedicine of the University of Eastern Finland, and they were published in Translational Sports Medicine. (2021-01-19)

NIH study compares low-fat, plant-based diet to low-carb, animal-based diet
People on a low-fat, plant-based diet ate fewer daily calories but had higher insulin and blood glucose levels, compared to when they ate a low-carbohydrate, animal-based diet, according to a small but highly controlled study at the National Institutes of Health. Led by researchers at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the study compared the effects of the two diets on calorie intake, hormone levels, body weight, and more. (2021-01-19)

Canadian researchers create new form of cultivated meat
Researchers at Canada's McMaster University have developed a new form of cultivated meat using a method that promises more natural flavour and texture than other alternatives to traditional meat from animals. (2021-01-19)

Fatty acid may help combat multiple sclerosis
The abnormal immune system response that causes multiple sclerosis (MS) by attacking and damaging the central nervous system can be triggered by the lack of a specific fatty acid in fat tissue, according to a new Yale study. The finding suggests that dietary change might help treat some people with the autoimmune disease. (2021-01-19)

Green med diet cuts non-alcoholic fatty liver disease by half - Ben-Gurion U. study
Overall, the green MED diet produced dramatic reductions in fatty liver. NAFLD prevalence dropped from 62% at baseline to 31.5% in the green Mediterranean group, down to 47.9% in the Mediterranean group and 54.8% in the healthy dietary regimen group. Addressing this common liver disease by targeted lifestyle intervention might promote a more effective nutritional strategy. This Ben-Gurion University of the Negev clinical trial demonstrates an effective nutritional tool for NAFLD beyond weight loss (2021-01-18)

Eating omega-3 fat helps hibernating Arctic ground squirrels warm up during deep cold
By feeding arctic ground squirrels special diets, researchers have found that omega-3 fatty acids, common in flax seed and fish oil, help keep the animals warmer in deep hibernation. (2021-01-14)

Medication shows promise for weight loss in patients with obesity, diabetes
A new study confirms that treatment with Bimagrumab, an antibody that blocks activin type II receptors and stimulates skeletal muscle growth, is safe and effective for treating excess adiposity and metabolic disturbances of adult patients with obesity and type 2 diabetes. (2021-01-13)

Short term low carbohydrate diet linked to remission of type 2 diabetes
Patients with type 2 diabetes who follow a strict low carbohydrate diet for six months may experience greater rates of remission compared with other recommended diets without adverse effects, suggests a study published by The BMJ today. (2021-01-13)

Scientists are a step closer to developing 'smart' stem cells - made from human fat
These new, adaptive stem cells can lie dormant until needed, a new animal study using human cells shows. (2021-01-13)

How the circadian clock regulates liver genes in time and space
EPFL scientists have carried out the first comprehensive study of how genes in the liver perform their metabolic functions in both space and time of day. Monitoring almost 5000 genes at the level of the individual cell across a 24-hour period, the researchers have modelled how the circadian clock and liver functions crosstalk throughout the day in sync with the feeding-fasting cycle. (2021-01-11)

Shriners Hospitals for Children study reveals new link to arthritis
A new study by investigators at the Shriners Hospital for Children -- St. Louis suggests the damaging effects of obesity are not due to body weight but rather come from something much smaller - biochemical signals released by fat cells. (2021-01-08)

Tracking the formation of the early heart, cell by cell
Richard Tyser and colleagues have mapped the origins of the embryonic mouse heart at single-cell resolution, helping to define the cell types that make up the heart in the earliest days of development. (2021-01-07)

Beating the bulge with a nice cup of tea
Researchers led by the University of Tsukuba found that healthy volunteers who consumed oolong tea every day had much higher levels of fat breakdown compared with the placebo group, and that the effects were most noticeable during sleep. Importantly, the volunteers developed a tolerance to caffeine over the 2-week study period, with their sleep patterns remaining unaffected by tea or caffeine consumption, indicating that oolong tea may have clinical relevance for weight control. (2021-01-06)

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