Current Fetus News and Events

Current Fetus News and Events, Fetus News Articles.
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Substance in the blood of pregnant women fights pathological immune reaction
Scientists studied the effect of trophoblastic β1-glycoprotein in the blood of pregnant women on pro-inflammatory immune cells. Thanks to trophoblastic β1-glycoprotein, a woman's body does not adversely react to the fetus and supports its normal development until birth. It turned out that trophoblastic β1-glycoproteins also suppressed the development of pro-inflammatory lymphocytes and reduced their activity. (2021-02-10)

In vitro study helps explain how Zika virus passes from mother to fetus during pregnancy
A preclinical study by a University of South Florida Health Morsani College of Medicine team has discovered a new mechanism for how Zika virus can pass from mothers to their children during pregnancy - a process known as vertical transmission. The researchers showed, for the first time, that specialized maternal cells lining the uterus (decidual cells) act as reservoirs for trimester-dependent transmission of the virus through the placenta. (2021-02-03)

First study to look at potency of maternal antibodies
In a new study to be presented today at the Society for Maternal-Fetal Medicine's (SMFM) annual meeting, The Pregnancy Meeting™, researchers will unveil findings that suggest that women who contract COVID-19 during pregnancy are able to make antibodies, but that transfer of these antibodies to their infants is less than expected. (2021-01-28)

Biomarkers in mother's plasma predict a type of autism in offspring with 100% accuracy
UC Davis MIND Institute researchers used machine learning to crunch 10,000 autoantibody pattern combinations to identify maternal biomarkers associated with a sub-type of autism. The findings have implications for early diagnosis and intervention. (2021-01-25)

Placental function can illuminate future disease in adults and children
Researchers at the University of Colorado Anschutz Medical Campus have discovered a direct association between placental function in pregnant women and future metabolic disorders in children and adults, a finding that could lead to earlier intervention and diagnosis of disease. (2021-01-22)

UTMB team proves potential for reducing pre-term birth by treating fetus as patient
The results of a study by researchers at the University of Texas Medical Branch may pave the way for a new medicine delivery system that could reduce the incidence of pre-term labor and premature birth by allowing physicians to treat the 'fetus as the patient'. The study has been published in Science Advances. (2021-01-22)

Estrogen receptors in mom's placenta critical during viral infection
A team of Duke and Mt. Sinai researchers has found a mechanism that protects a fetus from harm when the mother's innate immune system responds to a viral infection. Inflammation that would harm the fetus is dampened by a cell-surface estrogen receptor called GPER1 that is especially abundant in the placenta and fetal tissues. (2021-01-21)

How to find mutated sperm? Just go FISH
A test developed by Berkeley Lab scientists can quickly and easily detect whether sperm cells are carrying chromosomal defects, an advance that will help men who have undergone cancer treatment father healthy children. (2021-01-19)

New clues on why pregnancy may increase risk of organ transplant rejection
A research study at the University of Chicago has found that in pregnancy, while the T cell response to a fetus becomes tolerant to allow for successful pregnancy, the part of the immune system that produces antibodies (known as the humoral response) becomes sensitized, creating memory B cells that can later contribute to the rejection of a transplanted organ. (2021-01-04)

New research highlights the importance of a forgotten organ in ensuring healthy pregnancies
An international research team led by UBC has uncovered for the first time the importance of a small gland tucked behind the sternum that works to prevent miscarriage and diabetes in pregnant women. (2020-12-23)

The thymus as key to healthy pregnancies
How the immune system adapts to pregnancy has puzzled researchers for decades. An international team of researchers, including scientists from IMBA (Institute of Molecular Biotechnology) of the Austrian Academy of Sciences has now discovered that important changes in the thymus occur in order to prevent miscarriages and gestational diabetes. The results are published in the journal Nature. (2020-12-23)

Research reveals compromised transfer of SARS-CoV-2-specific antibodies through placenta
Lower than expected levels of protective SARS-CoV-2 antibodies pass through the placenta from mothers who are infected in the third trimester with the virus that causes COVID-19. This low level of transfer from mother to fetus may be caused by altered attachments of carbohydrates to the SARS-CoV-2-specific antibodies. (2020-12-23)

Pregnant women in third trimester unlikely to pass SARS-CoV-2 infection to newborns
Pregnant women who are infected with SARS-CoV-2, the virus that causes COVID-19, during the third trimester are unlikely to pass the infection to their newborns, suggests a study funded by the National Institutes of Health. The study followed 127 pregnant women who were admitted to Boston hospitals during the spring of 2020. Among the 64 pregnant women who tested positive for SARS-CoV-2, no newborns tested positive for the virus. (2020-12-22)

Pregnant women with COVID-19 pass no virus but fewer-than-expected antibodies to newborns
Pregnant women may be especially vulnerable to developing more severe cases of COVID-19, but little is known about their anti-SARS-CoV-2 immune response or how it may affect their offspring. A new study provides new insights that could help improve care for these women and their newborns and emphasizes the need for pregnant women to be considered in vaccine rollout plans. (2020-12-22)

Diet and lifestyle during pregnancy linked to modifications in infants' DNA
A new study has shown pregnant women with obesity could reduce the health risks for their infants through improved diet and more physical activity. (2020-11-06)

Study reveals factors that can make placenta less capable of protecting fetus from zika
Findings reported by Brazilian researchers in PLOS Neglected Tropical Diseases help explain why only some babies whose mothers are infected during pregnancy are born with microcephaly and other anomalies. (2020-10-27)

RUDN University doctors suggested ways to reduce obstetrical complications in endometriosis patients
A team of doctors from RUDN University with their Italian colleagues had studied the data of existing studies on the effect of endometriosis on pregnancy and childbirth and suggested ways to reduce obstetrical complications in women with this condition. (2020-10-14)

DNA test identifies genetic causes of severe fetal and newborn illness
A new study by University of California researchers shows the promise of high-throughput DNA-sequencing technologies to improve prenatal diagnosis and pregnancy outcomes for women who have experienced an abnormal prenatal ultrasound. (2020-10-07)

Detection of PCBs and their metabolites (OH-PCBs) in the fetal brain of a Japanese macaque
This study selected the Japanese macaque (Macaca fuscata) as a model animal for the fetal transfer of OH-PCBs in humans, and revealed OH-PCB concentrations and their relationships in the maternal and fetal brains. The key finding from this study is that OH-PCBs can reach the developing brain of the fetus as early as the first trimester of pregnancy. These OH-PCBs may exceed the levels that induce adverse effects on neurodevelopment. (2020-09-14)

'One size fits all' medication approach doesn't work in pregnancy
New research led by the University of South Australia shows that a blanket approach to prescribing medication during pregnancy may put low birth weight babies at risk for the rest of their lives. (2020-09-08)

Researchers identify proteins that prevent COVID-19 transmission through the placenta
Researchers from Boston Medical Center's Maxwell Finland Laboratory for Infectious Diseases have identified properties in placenta tissue that may play an important role in preventing the transmission of COVID-19 from a mother with the virus to her fetus. (2020-09-02)

Unravelling mother to baby transmission of Zika virus
Researchers have discovered that when a pregnant mother is infected by Zika virus, it can remain in the placenta for months, causing damage that can be dangerous to the fetus. These findings advance our understanding of mother to baby transmission and provide the groundwork for the future development of drugs and vaccines. (2020-09-01)

After Stillbirth, New Genetic Analyses May Give Parents Answers
Columbia researchers have uncovered an array of new genes that cause stillbirth, significantly increasing the understanding of the genetic foundations of common, but little studied, condition. (2020-08-12)

Globally, only half of women get treatment for preventable killer of newborns
Only half of pregnant women worldwide who need a 50-year-old treatment that prevents an often-fatal disease in fetuses and newborns receive it, Columbia researchers have found. (2020-08-10)

Prenatal depression alters child's brain connectivity, affects behavior
Altered brain connectivity may be one way prenatal depression influences child behavior, according to new research in JNeurosci. (2020-08-10)

Researchers found a link between genes and preeclampsia
Researchers have showed that HLA-G gene regulates male-to-female ratio at birth. The study strengthens earlier findings of the vulnerability of male fetuses to preeclampsia. (2020-07-14)

Immune system works differently between and first and later pregnancies
A study in Cell Reports shows the delicate physiological balancing act a mother's immune system must pull off to prevent a fetus from being rejected by the body works differently in first and second pregnancies. Researchers say this could lead to more personalized and effective therapeutic strategies to help prevent miscarriages, stillbirths and preterm births. (2020-06-23)

Defining paths to possible mother to child coronavirus transmission
UC Davis Health researchers took a critical step in defining the possible paths for SARS-CoV-2 causing COVID-19 to get transmitted from the mother to her newborn baby. (2020-06-23)

Non-invasive fetal oxygen monitor could make for safer deliveries
A device to directly measure blood oxygen saturation in a fetus during labor has been developed by researchers at UC Davis. By providing better information about the health of a fetus right before birth, the device could both reduce the rate of Cesarean sections and improve outcomes in difficult deliveries. (2020-06-17)

Tibetan antelope thrive at high altitudes using a juvenile form of blood oxygen transport
Adult Tibetan antelope have overcome oxygen deprivation on the high-altitude Tibetan Plateau through an unusual adaptation in which they permanently express a form of hemoglobin (the iron-containing oxygen transport protein in red blood cells) that other members of the cattle family only express as juveniles or when under extreme oxygen deprivation. (2020-06-17)

Extra choline may help pregnant women decrease negative effects of COVID-19 on their newborns
Pregnant women who take extra choline supplements may mitigate the negative impact that viral respiratory infections, including COVID-19, can have on their babies, according to a new study in the Journal of Psychiatric Research. (2020-06-01)

Imaging reveals unexpected contractions in the human placenta
High-resolution imaging of the human placenta provides new insights into blood circulation patterns that are crucial for fetal development, according to a study publishing May, 28 2020 in the open-access journal PLOS Biology by Penny Gowland of the University of Nottingham, and colleagues. These findings improve our understanding of the functioning of this understudied organ, both in healthy pregnancies and in serious medical conditions such as pre-eclampsia. (2020-05-28)

Even natural products can be harmful for the unborn child
Plant products ingested by pregnant women through their diet are broken down by the intestinal microbiota into chemical substances, some of which can cross the placental barrier and reach the fetus. These foreign substances can harm the unborn child, even if they are of 'natural origin'. Researchers at the Department for BioMedical Research (DBMR) at the University of Bern and Inselspital, University Hospital Bern, therefore warn against underestimating the effects of such substances. (2020-05-26)

Exposure to 'good bacteria' during pregnancy buffers risk of autism-like syndrome
Giving beneficial bacteria to stressed mothers during the equivalent of the third trimester of pregnancy prevents an autism-like disorder in their offspring, according to a new animal study. (2020-05-26)

Placentas from COVID-19-positive pregnant women show injury
In the largest study to examine health of placentas in women who tested positive for COVID-19, findings show placentas from 16 women who tested positive for COVID-19 while pregnant showed evidence of injury, according to pathological exams completed directly following birth. (2020-05-22)

New evidence for optimizing malaria treatment in pregnant women
The research, published today in The Lancet Infectious Diseases is the fruit of joint project between investigators from around the world to conduct the largest individual patient data meta-analysis to date under the WWARN umbrella. The study found that artemether-lumefantrine (AL) and other artemisinin-based combination therapies (ACTs) were significantly more effective than quinine, the current recommended treatment. Authors urgently call for further investigation into dose optimization for pregnant women to ensure the highest possible treatment success. (2020-04-29)

New evidence for optimising malaria treatment in pregnant women
The research, published in The Lancet Infectious Diseases is the fruit of joint project between investigators from around the world to conduct the largest individual patient data meta-analysis to date under The WorldWide Antimalarial Resistance Network?WWARN?umbrella. The study found that artemether-lumefantrine (AL) and other artemisinin-based combination therapies (ACTs) were significantly more effective than quinine, the current recommended treatment. Authors urgently call for further investigation into dose optimisation for pregnant women to ensure the highest possible treatment success. (2020-04-29)

COVID-19 and pregnancies: What we know
Amid the rapidly evolving global coronavirus disease 2019 (COVID-19) pandemic that has already had profound effects on public health and medical infrastructure across the globe, many questions remain about its impact on child health. New research published in the Journal of Clinical Virology indicates that the vulnerability of neonates and children and their role in the spread of the virus (severe acute respiratory syndrome coronavirus 2 [SARS-CoV-2]) should be included in preparedness and response plans. (2020-04-27)

Swamp wallabies conceive new embryo before birth -- a unique reproductive strategy
Reproduction specialists from the Leibniz Institute for Zoo and Wildlife Research (Leibniz-IZW), Germany, and the University of Melbourne, Australia, recently demonstrated that swamp wallabies ovulate, mate and form a new embryo before the birth of the previous offspring. They thereby continuously support embryos and young at different development stages before and after birth. (2020-03-02)

Stem cell transplants in utero offers TX for metabolic disorders that often end pregnancy
Administering stem cell or enzyme therapy in utero may be a path to alleviating some congenital diseases that often result in losing a pregnancy, according to a new study in mice by UC San Francisco researchers, who showed that stem cells can enter the fetal brain during prenatal development and make up for cells that fail to make an essential protein. (2020-02-26)

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