Current Gastroenterology News and Events | Page 2

Current Gastroenterology News and Events, Gastroenterology News Articles.
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Changes to gut microbiome may slow cancer growth in smokers
Changes to the gut microbiome interacted with the immune system to slow the growth of cancer in mice exposed to cigarette smoke, according to research that was selected for presentation at Digestive Disease Week® (DDW) 2020. DDW® data will be published in the May online supplements to Gastroenterology and GIE: Gastrointestinal Endoscopy. (2020-04-30)

Fecal transplantation improves outcomes in patients with multi-drug resistant organisms
Transferring fecal matter from the digestive systems of healthy donors to extremely ill patients who had previously been infected with drug-resistant bacteria resulted in shorter hospital stays, fewer bloodstream infections and infections that were easier to treat, according to research that was selected for presentation at Digestive Disease Week® (DDW) 2020. DDW® data will be published in the May online supplements to Gastroenterology and GIE: Gastrointestinal Endoscopy. (2020-04-30)

AGA and joint task force on allergy-immunology practice parameters release EoE guidelines
Eosinophilic esophagitis (EoE) is a chronic inflammatory disease of the esophagus triggered by allergens that causes difficulty with swallowing in adults, which grows more frequent and intense over time, affecting patients' quality of life. Children experience varied symptoms that include feeding difficulty, pain, vomiting, as well as dysphagia. EoE affects an estimated one in 2,000 people. (2020-04-28)

AGA releases official guidance for patients with IBD during the COVID-19 pandemic
Today, the American Gastroenterological Association (AGA) published new COVID-19 guidance for gastroenterologists treating patients with inflammatory bowel disease (IBD): AGA Clinical Practice Update on Management of Inflammatory Bowel Disease During the COVID-19 Pandemic: Expert Commentary. (2020-04-10)

AGA issues formal recommendations for PPE during gastrointestinal procedures
Today, the American Gastroenterological Association (AGA) published new COVID-19 recommendations in Gastroenterology, the official journal of the AGA: AGA Institute Rapid Recommendations for Gastrointestinal Procedures During the COVID-19 Pandemic. (2020-04-01)

Editorial calls for a precision medicine approach to follow-up of diverticulitis
An editorial challenges physicians and the US healthcare system to reconsider the current 'one size fits all' care for diverticulitis and to employ a precision medicine approach to determine which patients should be referred for colonoscopy. (2020-03-30)

Mount Sinai researchers unveil mechanisms to prevent Crohn's disease
In a series of four studies published today in Gastroenterology, a journal of the American Gastroenterological Association, Mount Sinai inflammatory bowel disease (IBD) researchers, describe the identification of predictive tools and a new understanding of environmental factors that trigger IBD. (2020-03-26)

Digestive symptoms are prominent among COVID-19 patients reveals study in The American Journal of Gastroenterology
The American Journal of Gastroenterology published today a new study that reveals digestive symptoms, including diarrhea, are common in COVID-19 patients. The study comes from the Wuhan Medical Treatment Expert Group for COVID-19 in China. (2020-03-18)

New COVID-19 info for gastroenterologists and patients
A paper published today in Clinical Gastroenterology and Hepatology by clinicians at Icahn School of Medicine at Mount Sinai outlines key information gastroenterologists and patients with chronic digestive conditions need to know about COVID-19, or coronavirus. (2020-03-18)

Acid reflux drugs linked to increased fracture risk in kids
Proton pump inhibitors -- a widely used class of drugs used to treat acid reflux and related symptoms - may lead to an increased risk of fractures in children and adolescents, reports a study in the Journal of Pediatric Gastroenterology and Nutrition (JPGN). Official journal of the North American Society for Pediatric Gastroenterology, Hepatology and Nutrition (NASPGHAN) and the European Society for Paediatric Gastroenterology, Hepatology and Nutrition, JPGN is published by Wolters Kluwer. (2020-03-17)

Immunosuppressive therapy for inflammatory bowel disease does not increase women's risk of vulvar or vaginal cancer
In a new retrospective study, researchers found that the use of immunosuppressive therapy does not increase the occurrence or recurrence of vulvar or vaginal cancer in women with inflammatory bowel disease (IBD). However, earlier onset of cancer was reported, and lymphomas were found in some patients, which is very rare in the genital tract. Their results appear in Digestive and Liver Disease, published by Elsevier. (2020-03-11)

GI symptoms and potential fecal transmission in coronavirus patients
In two new papers published online in Gastroenterology, investigators from China describe the impact of coronavirus on the digestive tract. Here are the key findings. (2020-03-05)

Using artificial intelligence to assess ulcerative colitis
Researchers from Tokyo Medical and Dental University (TMDU) have developed an artificial intelligence system with a deep neural network that can effectively evaluate endoscopic data from patients with ulcerative colitis, which is a type of inflammatory bowel disease, without the need for biopsy collection. The system was able to identify patients in both endoscopic remission and histologic remission with comparable accuracy to experts, representing a gain in terms of efficiency and costs. (2020-03-05)

CHOP researchers develop novel approach to capture hard-to-view portion of colon in 3D
In a groundbreaking discovery, researchers at Children's Hospital of Philadelphia (CHOP) developed a new imaging method that allows scientists to view the enteric nervous system (ENS) -- a key part of the human colon -- in three dimensions by making other colon cells that normally block it invisible. The ENS has previously only been visible in thin tissue slices that provide limited clinical information. (2020-02-27)

Potential new heartburn drug studied at VUMC
An investigational drug that binds bile acids in the stomach can reduce the severity of heartburn symptoms in patients with treatment-resistant gastroesophageal reflux disease (GERD) when combined with a proton pump inhibitor (PPI), a new study suggests. (2020-02-26)

GI societies issue updated colorectal cancer screening recommendations
These evidence-based recommendations support closer follow-up after colonoscopy screenings for some groups, less intense follow-up for others, and provide guidance for removing colorectal polyps. (2020-02-18)

New AGA guideline outlines treatment best practices for ulcerative colitis patients
An increasing number of drugs are available for long-term management of moderate to severe UC, leading to questions about treatment strategies for optimal patient care. A new clinical guideline from the American Gastroenterological Association, published in Gastroenterology, the official journal of the AGA Institute, provides recommendations for the management of adult outpatients with moderate to severe UC as well as adult hospitalized patients with acute severe ulcerative colitis (ASUC). (2020-01-21)

Obesity crisis blamed for a rise in fatty liver disease amongst young adults
One in five young people have fatty liver disease (steatosis), with one in 40 having already developed liver scarring (fibrosis), research published today has found. The study, published in The Lancet Gastroenterology & Hepatology, is the first to attempt to determine the prevalence of fatty liver disease and fibrosis in young healthy adults in the UK. (2020-01-15)

Processed foods highly correlated with obesity epidemic in the US
A review article from the George Washington University highlights the correlation between highly processed foods and increased prevalence of obesity in the United States. (2020-01-06)

Acid reflux affects nearly a third of US adults weekly
Gastroesophageal reflux disease (GERD), a digestive disorder that causes hearburn and other uncomfortable symptoms, may affect nearly a third of US adults each week, and most of those who take certain popular medications for it still have symptoms, according to a new Cedars-Sinai study. (2019-12-19)

AGA releases guideline on management of gastric intestinal metaplasia
This guideline will aid health care provider decision-making for patients who are undergoing upper endoscopy in North America (2019-12-10)

Young people with IBD five times more likely to develop serious infections
Young patients with inflammatory bowel disease (IBD) are five times more likely than the general population to develop viral infections that can lead to hospitalisation or permanent organ damage, a new study published in the UEG Journal has found. (2019-12-05)

Gut microbiota imbalance promotes the onset of colorectal cancer
Researchers have demonstrated that an imbalance in the gut microbiota, also known as 'dysbiosis', promotes the onset of colorectal cancer. The teams demonstrated that transplanting fecal flora from patients with colon cancer into mice caused lesions and epigenetic changes characteristic of the development of a malignant tumor. The pilot study led to the development of a non-invasive blood test which identifies the epigenetic phenomenon associated with dysbiosis. The test was validated in 1,000 individuals. (2019-11-18)

Eliminating common bacterial infection significantly decreases gastric cancer risk
Penn researchers are first to assess Helicobacter pylori infection and gastric cancer risk in Americans, certain demographics and ethnic groups. (2019-11-13)

Half of all commonly used drugs profoundly affecting the gut microbiome, warn experts
The drug categories found to have the biggest impact on the microbiome include, proton pump inhibitors (PPIs), metformin, antibiotics and laxatives. (2019-10-22)

Colorectal and pancreatic cancer rates up 10% in last 30 years, reveals major study
The results of a major study across 195 countries, presented today at UEG Week Barcelona 2019, indicate that global death rates for pancreatic cancer and incidence rates for colorectal cancer both increased by 10% between 1990 and 2017. (2019-10-21)

IBD prevalence three times higher than estimates and expected to rise, new study reveals
The new evidence demonstrates that IBD prevalence is three times higher than previously reported, with ulcerative colitis and Crohn's Disease prevalence increasing by 55% and 83% respectively between 2000 and 2017. (2019-10-20)

FMT is effective in IBS, but having a 'super-donor' is essential, new study finds
The study reported today, which involved a large cohort of patients with various subtypes of IBS, used several enhanced methodologies, and highlighted the importance of donor selection for optimizing the effectiveness of FMT as a treatment for IBS. (2019-10-20)

Microbiome provides new clues to determining development of colon cancer
Findings showcasing a connection between bacteria in the microbiome and colon cancer, which may be used to screen younger populations at risk, were published in the journal Gastroenterology by researchers from the George Washington University. (2019-10-04)

TAU and Ichilov researchers develop treatment for familial adenomatous polyposis
Researchers from Tel Aviv University and Tel Aviv Sourasky Medical Center (Ichilov Hospital) have developed an innovative drug treatment for familial adenomatous polyposis (FAP), a rare, inherited condition that affects adolescents and young adults and often leads to colorectal cancer. (2019-10-03)

Better methods needed for predicting risk of liver disease
While blood samples can reliably identify people with a low risk of developing severe liver disease, better methods are needed in primary care for identifying people in most need of care. These are some of the conclusions of a large registry-based study by researchers at Karolinska Institutet in Sweden published in the esteemed journal Gastroenterology. (2019-09-27)

Changes in internal medicine subspecialty choices of women, men
This study used enrollment data to examine changes in the internal medicine subspecialty choices of women and men from 1991 to 2016. Data were examined for 9 internal medicine subspecialties: cardiovascular disease, endocrinology, gastroenterology, geriatric medicine, hematology and oncology, infectious disease, nephrology, pulmonary disease and critical care, and rheumatology. (2019-09-23)

AGA releases guideline on the evaluation of chronic diarrhea
Diagnosing patients with chronic watery diarrhea can be difficult for health care providers, since several causes with specific therapies, such as inflammatory bowel disease (IBD), microscopic colitis and chronic infection, need to be ruled out. A new clinical guideline1 from the American Gastroenterological Association (AGA) published in Gastroenterology, the official journal of the AGA Institute, provides recommendations on the appropriate laboratory tests based on current evidence to exclude other diagnoses in the setting of suspected functional diarrhea or irritable bowel syndrome with diarrhea (IBS-D). (2019-09-23)

Study: Obesity associated with abnormal bowel habits -- not diet
Because researchers at Beth Israel Deaconess Medical Center demonstrated for the first time that a strong association between obesity and chronic diarrhea is not driven by diet or physical activity, the findings could have important implications for how physicians might approach and treat symptoms of diarrhea in patients with obesity differently. (2019-09-18)

Nemours study finds genetic analysis can aid treatment of eosinophilic Esophagitis
Personalized medicine -- where the proper medicine and proper dose are used for the individual patient -- moved a step closer to reality for children suffering from eosinophilic esophagitis (EoE), an inflammation of the food pipe often caused by an allergic reaction to certain foods. (2019-09-12)

A new pathway: researchers identify potential treatment target for Crohn's disease
Crohn's disease is a form of inflammatory bowel disease (IBD) in which the body's own immune system attacks the gastrointestinal tract, and treatment is focused on controlling the symptoms of the disease in its acute phase and managing it in remission. But recently, researchers at Case Western Reserve University School of Medicine identified a pathway in the immune system activated in CD and which holds promise for investigating new treatments. (2019-08-08)

FEFU scientists likely found way to grow new teeth for patients
A group of histologists and dentists from School of Biomedicine, Far Eastern Federal University (FEFU), teamed up with Russian and Japanese colleagues and found cells that are probably responsible for the formation of human dental tissue. Researchers propose to apply the study outcome within the development of bioengineering techniques in dentistry aimed at growing new dental tissue for patients. A related article is published in the International Journal of Applied and Fundamental Research. (2019-06-27)

Intelligent testing could save lives by defusing ticking time bomb of liver disease
An innovation in liver function testing could detect liver disease decades before it becomes fatal. (2019-06-25)

Processed foods may hold key to rise in autism
University of Central Florida researchers are now a step closer to showing the link between the food pregnant women consume and the effects on a fetus' developing brain. (2019-06-20)

Scientists identify genes associated with biliary atresia survival
Scientists at Cincinnati Children's Hospital Medical Center have identified an expression pattern of 14 genes at the time of diagnosis that predicts two year, transplant-free survival in children with biliary atresia -- the most common diagnosis leading to liver transplants in children. (2019-06-19)

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