Current Gene News and Events | Page 2

Current Gene News and Events, Gene News Articles.
Sort By: Most Relevant | Most Viewed
Page 2 of 25 | 1000 Results
New approach to diagnosing genetic diseases using RNA sequencing increases yield
A new study from Baylor College of Medicine finds that starting genetic analysis with RNA sequencing can increase diagnostic yield and confidence in diagnosis. (2020-10-27)

Acute kidney injury among African Americans with sickle cell trait and disease
New research examines the risk of acute kidney injury in people with sickle cell trait or disease, as well as the effect of acute kidney injury on kidney function decline in these individuals. Results from the study will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25. (2020-10-23)

Rutgers finds new way to personalize treatments for prostate cancer
Rutgers researchers have discovered human gene markers that work together to cause metastatic prostate cancer - cancer that spreads beyond the prostate. (2020-10-19)

Researchers identify the mechanism behind bone marrow failure in Fanconi anaemia
Researchers at the University of Helsinki and the Dana-Farber Cancer Institute have identified the mechanism behind bone marrow failure developing in children that suffer from Fanconi anaemia. (2020-10-14)

Treating cystic fibrosis with mRNA therapy or CRISPR
The potential for treating cystic fibrosis (CF) using mRNA therapies or CRISPR gene editing is possible regardless of the causative mutation. CF clinical trials showing that a genotype-agnostic gene therapy for CF is possible (2020-10-08)

Hidden DNA fragment the 'trigger switch' for male development
Biology textbooks may need to be re-written, with scientists finding a new piece of DNA essential to forming male sex organs in mice. (2020-10-02)

Mosquitos lost an essential gene with no ill effects
University of Maryland scientists discovered mosquitos are missing a gene that's critical for survival in other insects. Alys Jarvela noticed the missing gene and went on the hunt to find out how mosquitos survive without it. She identified the first example of nature swapping out closely related genes, a phenomenon that poses caveats for studies using model organisms as proxies for other species. The research was published September 30, 2020, in Communications Biology. (2020-09-30)

Neandertal gene variant increases risk of severe COVID-19
A study published in Nature shows that a segment of DNA that causes their carriers to have an up to three times higher risk of developing severe COVID-19 is inherited from Neandertals. The study was conducted by researchers at Karolinska Institutet and Max Planck Institute for Evolutionary Anthropology. (2020-09-30)

Even in people with Parkinson's gene, coffee may be protective
Even for people with a gene mutation tied to Parkinson's disease, coffee consumption may be associated with a lower risk of actually developing the disease, according to a new study published in the September 30, 2020, online issue of Neurology®, the medical journal of the American Academy of Neurology. (2020-09-30)

Inflammatory gene provides clue to obesity risk
A gene that helps to control inflammation increases the risk of obesity and could be turned off in mice to stop weight gain, a study from The University of Queensland has found. (2020-09-29)

New 'atlas' of human heart cells first step toward precision treatments for heart disease
Scientists have for the first time documented all of the different cell types and genes expressed in the healthy human heart, in research published in the journal Nature. Cardiologists from the Mazankowski Alberta Heart Institute at the University of Alberta joined teams from Cambridge, Boston and Berlin to use state-of-the-art analytical techniques to sequence the ribonucleic acids (RNA) in nine types of single cells from six regions of the heart. (2020-09-24)

New genes for human deafness found in Israeli families
Until now, only seven genes were known to be involved in hearing loss in Israel's Jewish population. A new study from the Sackler Faculty of Medicine at Tel Aviv University has found that 32 genes are responsible for inherited hearing loss in Israeli Jewish families. The researchers also identified a mutation in a gene not previously recognized to cause hearing loss in humans. The research has immediate implications for genetic counseling for families with hearing loss and for care of children with hearing loss. (2020-09-23)

Pale melanomas masked by albino gene
People with pale coloured melanomas are more likely to have a gene mutation associated with albinism, University of Queensland research has found. (2020-09-23)

Promising computer simulations for stellarator plasmas
The turbulence code GENE (Gyrokinetic Electromagnetic Numerical Experiment), developed at Max Planck Institute for Plasma Physics (IPP) at Garching, Germany, has proven to be very useful for the theoretical description of turbulence in the plasma of tokamak-type fusion devices. Extended for the more complex geometry of stellarator-type devices, computer simulations with GENE now indicate a new method to reduce plasma turbulence in stellarator plasmas. This could significantly increase the efficiency of a future fusion power plant. (2020-09-18)

Biologists create new genetic systems to neutralize gene drives
Addressing concerns about gene drive releases in the wild, UC San Diego scientists and their colleagues have developed two new genetic systems that halt or eliminate gene drives after release. Created in fruit flies, the e-CHACRs and ERACRs are powerful gene drive control mechanisms that were meticulously developed and tested at the genetic and molecular levels. (2020-09-18)

Gene therapy corrects the cardiac effects of Friedreich's ataxia
Gene therapy was successfully used to overcome the cardiac effects of Freidreich's ataxia (FA) in a mouse model of the disease (2020-09-18)

Research shows potential of gene editing in barley
An international team of plant scientists have shown the potential to rapidly improve the quality of barley grain through a genetic tool known as CRISPR or gene editing. (2020-09-17)

Are male genes from Mars, female genes from Venus?
In a new paper in the PERSPECTIVES section of the journal Science, Melissa Wilson reviews current research into patterns of sex differences in gene expression across the genome, and highlights sampling biases in the human populations included in such studies. (2020-09-11)

GTEx studies reveal variation in gene expression among individuals and, to small degree, by sex
Seven new studies from Science and Science Advances present the third and final phase of the Genotype-Tissue Expression (GTEx) project, begun over a decade ago by scientists aiming to better understand the effects of genetic diversity in healthy individuals. (2020-09-10)

Biological sex affects genes for body fat, cancer, birth weight
Biological sex has a small but ubiquitous influence on gene expression in almost every type of human tissue, reports a new study. These sex differences are observed for genes involved in many functions, including how people respond to medication, how women control blood sugar levels in pregnancy, how the immune system functions, how cancer develops and male pattern baldness. The information could be used for diagnostics, drug development and predicting outcomes. (2020-09-10)

New insights into evolution of gene expression
The long-term expression of genes in vertebrate organs predisposes these genes to be subsequently utilized in other organs during evolution. The scientists Kenji Fukushima and David D. Pollock report this finding in the journal Nature Communications. (2020-09-08)

New insight into mammalian stem cell evolution
The genes regulating pluripotent stem cells in mammals are surprisingly similar across 48 species, Kyoto University researchers report in the journal Genome Biology and Evolution. The study also shows that differences among these 'gene regulating networks' might explain how certain features of mammalian pluripotent stem cells have evolved. (2020-09-07)

Gene therapy: Novel targets come into view
Retinitis pigmentosa is the most prevalent form of congenital blindness. Using a retinitis pigmentosa mouse model, researchers from Ludwig-Maximilians Universitaet (LMU) in Munich have now shown that targeted activation of genes of similar function can compensate for the primary defect. (2020-09-02)

Newly identified gene grants tomatoes resistance to bacterial speck disease
Bacterial speck disease, which reduces both fruit yield and quality, has been a growing problem in tomatoes over the last five years. Because the culpable bacterium, Pseudomonas syringae, prefers a cool and wet climate, crops in places such as New York State have been particularly susceptible. Researchers at the Boyce Thompson Institute have uncovered the first known gene to impart resistance to a particular strain of the bacterium that causes speck disease. (2020-09-02)

Investigational new therapy prevents onset of Dravet syndrome symptoms in mice
In a development that may finally offer hope to children with Dravet syndrome and their parents, a promising investigational new therapeutic appears to alter the destructive course of the deadly disease in a mouse model. (2020-08-26)

The secret life of melons revealed: "Jumping sequences" may alter gene expression
Researchers from the University of Tsukuba have found in a comparison of melon genomes that retrotransposons (a.k.a. ''jumping sequences'') may affect gene expression. Fruit ripening physiology varies widely in melons, and retrotransposons may have contributed to changes in gene expression as melon genomes diversified. Some retrotransposon sequences were transcriptionally induced under heat stress, suggesting that retrotransposons were responsive to this kind of stress, and may affect the expression of genes that induces fruit ripening. (2020-08-25)

A multicenter look at gene therapy for spinal muscular atrophy
A new study confirms the safety and efficacy of gene therapy in children with spinal muscular atrophy under two years old. (2020-08-25)

Engineered capsids for efficient gene delivery to the eye
A rational design approach created novel variants of adeno-associated viral (AAV) capsids. These have improved transduction properties in the mouse retina and cornea. (2020-08-13)

Gene therapy targets inner retina to combat blindness
Batten disease is a group of fatal, inherited lysosomal storage disorders that predominantly affect children. The most prevalent form is CLN3 disease, for which there is no cure. Retinal degeneration and resulting vision loss is one of the symptoms. (2020-08-10)

Integration of gene regulatory networks in understanding animal behavior
For years, scientists have attributed animal behavior to the coordinated activities of neuronal cells and its circuits of neurons, known as the neuronal network (NN). However, researchers are pushing the boundaries in understanding animal behavior through the integration of gene regulation. (2020-08-07)

Move over Akita: Introducing 'Kuma mutant' mice for islet transplantation research
Scientists at the Tokyo Institute of Technology (Tokyo Tech) have used a gene editing technique to establish a novel mouse model of permanent neonatal diabetes--the immune-deficient Kuma mutant mice with a specific deletion in the Insulin2 (Ins2) gene. This model is expected to be useful for studying the mechanisms governing insulin-producing cell dysfunctions in the pancreas as well as for evaluating human stem-cell derived or interspecies-derived insulin-producing cell transplantation. (2020-08-05)

Stretches of repeating DNA predispose to systemic sclerosis
Researchers from the University of Tsukuba found that extended repeats of DNA in the gene FLI1 are associated with systemic sclerosis. By comparing the DNA of systemic sclerosis patients with healthy controls, they found that GA repeats over 22 are associated with the development of the disease as well as with a more severe outcome. These findings help us understand how FLI1 may contribute to the pathogenesis of systemic sclerosis. (2020-08-03)

Meet Cosmo, a bull calf designed to produce 75% male offspring
Scientists at the University of California, Davis, have successfully produced a bull calf, named Cosmo, who was genome-edited as an embryo so that he'll produce more male offspring. (2020-07-23)

Cells react differently to genomic imprinting
We inherit half of our genes from each parent. For their function of most genes, it doesn't matter which parent a gene comes from. But this is not true for all genes: about 150 genes are subject to ''genomic imprinting''. They are active either only if inherited from the mother, or only father. Most ''imprinted'' genes are important for our development. Professor Simon Hippenmeyer, IST Austria, shows that brain cells react differently to genomic imprinting. (2020-07-23)

Site-directed mutagenesis in wheat via haploid induction by maize
Site-directed mutagenesis facilitates the experimental validation of gene function and can speed up plant breeding by producing new biodiversity or by reproducing previously known gene variants in other than their original genetic backgrounds. However, its application is challenging in wheat owing to high genomic redundancy and highly genotype-dependent DNA transfer methods. (2020-07-21)

Researchers found a link between genes and preeclampsia
Researchers have showed that HLA-G gene regulates male-to-female ratio at birth. The study strengthens earlier findings of the vulnerability of male fetuses to preeclampsia. (2020-07-14)

Studying nearly 300 recently identified antibodies to SARS-CoV-2 reveals a common theme
An analysis of nearly 300 recently identified human SARS-CoV-2 antibodies uncovered a gene frequently used in antibodies that most effectively target the virus. (2020-07-13)

Common inherited genetic variant identified as frequent cause of deafness in adults
A common inherited genetic variant is a frequent cause of deafness in adults, meaning that many thousands of people are potentially at risk, reveals research published online in the Journal of Medical Genetics. (2020-07-06)

New Human Gene Therapy editorial: Concern following gene therapy adverse events
Response to the recent report of the deaths of two children receiving high doses of a gene therapy vector (AAV8) in a Phase I trial for X-linked myotubular myopathy (MTM). The news ''is a tragic reminder of how difficult it is to predict outcomes in first-in-human studies (2020-07-02)

Toward principles of gene regulation in multicellular systems?
Quantitative biologists from Northwestern combine precision measurements and mathematical models to uncover a common mechanism regulating gene expression during development. (2020-06-30)

Page 2 of 25 | 1000 Results
   First   Previous   Next      Last   
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.