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Current Genetic Information News and Events, Genetic Information News Articles.
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Gene therapy may increase cancer cure rates, medical physicists show
An innovative combination of two medical procedures-gene therapy and radiation therapy--can increase cancer cure rates by significant amounts compared to the cure rates offered by conventional radiation therapy alone, a Virginia Commonwealth University (VCU) team has concluded. (2002-08-13)

2002 American Society of Human Genetics Annual Meeting to be held in Baltimore, Oct. 15-19
The international genetics community will be represented by more than 3,000 scientists presenting their most recent research at the 52nd Annual Meeting of The American Society of Human Genetics to be held in Baltimore, Maryland at the Baltimore Convention Center from October 15-19, 2002. Members of the press are invited to attend. There will be free registration for the press and full access to all meeting sessions. More information to come. (2002-08-02)

Genetic factor underlies weight gain after use of antipsychotic drugs
Authors of a research letter in this week's issue of THE LANCET suggest that there is a genetic basis for the weight gain associated with the use of antipsychotic drugs. (2002-06-13)

University of Louisville leads project to customize ethics training for genetic researchers
The National Human Genome Research Institute is funding a three-year, $1.3 million project to develop a training program in genetic ethics that can be customized to match different types of genetic research. (2002-05-30)

New NIST procedure seeks improved diagnosis of Fragile X syndrome
Fragile X syndrome is the most common cause of inherited mental retardation. A new NIST system for measuring a specific class of genetic elements is working toward more accurate diagnosis of this disorder. Find out in this release how the system works and what it may soon mean to families worried about the threat of Fragile X syndrome. (2002-05-13)

Scientists identify DNA flanking region as trigger for genetic instability
Scientists at The Hospital for Sick Children and the University of Toronto have shown that the DNA flanking region in a family of neurological disorders is triggering the genetic mutation that underlies these diseases. This research is reported in the May issue of the scientific journal Nature Genetics. (2002-04-21)

Genetic tests could define us all as patients
Genetic science could drive a new wave of medicalisation if genetics tests are accepted without appropriate evaluation, warn researchers in this week's BMJ. (2002-04-11)

Genetic variants put some patients at risk for particular drug reactions
This is one of the first studies to show an association between genetic variants and the risk of a serious adverse drug reaction. Genetic variants in the human enzyme that metabolizes the drug warfarin, the frequently prescribed anticoagulant Coumadin, make some patients more susceptible to serious or life-threatening bleeding. (2002-04-02)

Genomics and public health
Michigan Center for Genomics and Public Health at the University of Michigan is one of three funded nationally by the Centers for Disease Control and Prevention to increase the understanding and use of the human genome in public health practice. (2002-03-25)

Ethical issues and the study of the human genome
The characterization of the human genome through the mapping and sequencing of human DNA is giving us new insight into our genetic heritage. A number of ethical issues raised by our increased understanding of the human genome and the application of new genetic technologies will be addressed. What limits, if any, should we set to our growing genetic knowledge and technology? (2002-03-05)

Genes are of little importance in rheumatoid arthritis
Researchers in Denmark surveyed over 37,000 twins about rheumatic diseases. Twin studies are one of the simplest ways to unravel the relative importance of genetic and environmental effects of a disease. Twins who reported that they had rheumatoid arthritis were invited to have a clinical examination. (2002-01-31)

Mechanisms of disease
January 2002 heralds the arrival of a new section in THE LANCET-Mechanisms of Disease-which aims to explain the relevance of new research, mainly from a genetic and molecular perspective, and its relevance to practising clinicians working in general medicine. (2002-01-03)

Comprehensive set of vision genes discovered: Identification could help in diagnosing and treating blinding diseases
Harvard Medical School researchers have discovered nearly all the genes responsible for vision, which could help in diagnosing and treating blinding diseases. Macular degeneration alone affects twenty-five percent of people over age 75. The discovery of the full set of photoreceptor genes expressed in the retinal cells, which was made in mice, could also lead to new methods for preserving and restoring the vision of those affected. (2001-11-29)

Adelaide scientists make HIV a safe aid in gene therapy
Researchers at the Women's and Children's Hospital, Adelaide have today published a paper in Human Gene Therapy in which they have shown that Human Immunodeficiency Virus Type 1 (HIV-1), after modification can be safely used to transfer therapeutic genes into human cells without transferring the disease.The use of this HIV-1 transfer approach has wide applicability for gene therapy in a variety of human genetic diseases. (2001-11-19)

Potential of tailoring drugs to genetic makeup confirmed--but challenges remain
At a time when harmful drug reactions are thought to rank just after strokes as a leading cause of death in the U.S., the potential benefits of tailoring drugs to a patient's genetic makeup have been confirmed in a systematic study led by University of California, San Francisco scientists. (2001-11-13)

Genes have a much greater role than environmental factors in asthma
Genes are likely to have a much bigger role than environmental factors in asthma, suggests research on twins in the Archives of Disease in Childhood. The UK, Australia and New Zealand have the highest rates of asthma in the world, with between 17 and 30 per cent of the population affected. (2001-10-21)

Opportunities and risks of genetically modified food
Using genetically modified plants and micro-organisms in food production helps secure food for the world population and protect the natural resources in the sense of sustainable agriculture. This is the result the Senate commission on genetic research of the Deutsche Forschungsgemeinschaft (DFG) has arrived at in its (2001-09-24)

Mothers transmit DNA through daughters only
Scientists have argued whether or not the often-studied mitochondrial DNA molecule is clonally inherited. It is with assuming clonal inheritance this type of DNA has been used to track the origin of modern human as well as to draw pictures of genetic relationships among other animals and plants. The conflict has now been solved by two evolutionary geneticists from Uppsala University in Sweden. (2001-09-06)

Masking genetic mutations
We don't realize the full extent of our genetic mutations. As published in Genes & Development, a group of scientists from the National Cancer Center Research Institute in Tokyo, Japan have identified a key regulator of the expression of genetic mutations and, in the process, have developed an intriguing therapeutic approach to combat prevalent genetic disorders. (2001-08-31)

U of Minnesota researchers identify gene for myotonic muscular dystrophy Type 2
University of Minnesota researchers have pinpointed the gene on chromosome 3 that causes myotonic dystrophy Type 2 (DM2). The findings will be reported in the August 3 issue of Science. (2001-08-02)

Marine snail study suggests conservation efforts should move beyond genetic diversity
A study of climate-induced evolutionary change in a California intertidal snail suggests that conservation plans for protecting endangered or threatened species should not focus exclusively on genetic diversity. (2001-05-30)

Experts discuss recommendations of NY state task force on genetic testing
A symposium on May 30 at NYU School of Medicine will discuss the NY State Task Force's recent recommendations for safe and effective genetic testing. Sponsors are: The Master Scholars Program at NYU School of Medicine, New York Academy of Medicine, and the NY State Task Force on Life and the Law. (2001-05-22)

Indian caste groups have differing genetic relationships to Europeans and Asians
A new study of genetic data shows that the ancestors of Indian men came from different parts of the world than those of Indian women and produced modern upper caste Indian populations that are genetically more similar to Europeans and lower caste populations that are more similar to Asians. (2001-05-14)

Genetic testing programs could overwhelm health care systems, says new report
The good news from human genome research is that tests to determine people's genetic susceptibility to many common and deadly diseases are already, or soon will be, available. The bad news, according to a University of Toronto report in the May 12 edition of the British Medical Journal, is that most health care systems risk being overwhelmed unless they start preparing for the complex and costly demands of genetic screening programs. (2001-05-09)

Jefferson scientist receives award to develop test to find genetic signatures of cancer
A scientist at Jefferson Medical College has been awarded a one-year grant for $100,000 from the National Cancer Institute's Early Detection Research Network to develop a test to detect bits of genetic information in the urine, including DNA from tumors or developing fetuses. (2001-05-08)

UCLA geneticists identify cause of malformed genitalia, finding will improve sex assignments in ambiguous newborns
A duplicated sex gene can convert a human embryo from male to female, often resulting in ambiguous genitalia, report UCLA researchers in the May edition of the American Journal of Human Genetics. The findings offer a new method to help physicians more accurately and quickly diagnose an affected infant's gender. (2001-04-30)

Genetic counseling may influence women's treatment choices, Lombardi study finds
Preliminary results of a research study at Lombardi Cancer Center indicate that newly diagnosed breast cancer patients with a strong family history of this disease are more likely to take more aggressive steps to eradicate their cancer if genetic testing shows they have the inherited form of the disease. (2001-04-22)

Sequencing the human genome: unraveling the mysteries of health and disease
AAAS is presenting a series of breakfast seminars on concerns related to genetic discrimination for Members of Congress, their staffs, and the interested public. The first in this series will take place April 3, 2001 at the Rayburn House Office Building and will feature Dr. Francis S. Collins, director of the National Human Genome Research Institute at NIH. (2001-03-27)

Study questions value of genetic advice on breast cancer in primary care
The value of giving genetic advice on breast cancer in primary care is questionable, according to research from the Netherlands published in this week's BMJ. (2001-01-04)

Study questions value of genetic advice on breast cancer in primary care
The value of giving genetic advice on breast cancer in primary care is questionable, according to a study in this week's BMJ. (2001-01-03)

Three genetic steps convert normal mammary cells into breast cancer cells
Cells originating from normal human breast tissue have been converted into breast cancer cells by a defined protocol of genetic changes. Scientists from MIT report that the sequential introduction of three cancer-associated genes into human mammary cells renders these cells tumorigenic. This study is the first report of the successful transformation of epithelial cells originating from a differentiated adult tissue such as the mammary gland. (2000-12-31)

Study finds substantial genetic basis for risk of periodontal disease
New research provides further evidence that a person's genes play a major role in the onset and severity of periodontal disease. The study concluded that approximately half of the variance in periodontal disease in the population can be attributed to genetic differences. (2000-11-29)

The Gene Media Forum presents: What Can We Expect?
A look at how the genetic revolution will affect our lives one year, five years, ten years from now... Renowned leaders in the genetic revolution discuss the future of genetics in one of two public programs for Paradise Now: Picturing the Genetic Revolution. (2000-09-07)

Study finds some people genetically predisposed to tuberculosis
In the August issue of The American Journal of Human Genetics, a report presents evidence for a major genetic component to TB susceptibility. People with at least one high-risk copy of this genetic region are ten times more likely to develop TB. A better understanding of the genes involved in this susceptibility should lead to better control of infection and better treatment for tuberculosis. (2000-07-13)

Jews are the genetic brothers of Palestinians, Syrians, and Lebanese
A new study of the Y chromosome reveals Jews are the genetic brothers of Palestinians, Syrians and Lebanese. (2000-05-07)

Interest in genetic testing for colon cancer high among people with family history
People with a family history of colon cancer express strong interest in having genetic testing, but many do not take advantage of already available screening tests for the disease, researchers from the University of Utah report. (2000-03-15)

Researchers seek siblings with Parkinson's disease for national genetic study
Researchers are seeking siblings diagnosed with Parkinson's disease to identify the genetic markers that may indicate a predisposition for developing this movement disorder. Indiana University School of Medicine is the principal institution among 49 centers in the U.S., Puerto Rico and Canada participating in five-year PROGENI (Parkinson's Research: The Organized Genetic Initiative)study. (2000-02-27)

AAAS statement on genetic discrimination
Genetic variation among individuals, a universal fact of life with great potential for scientific and social advances, should never be used as a tool for discrimination, the American Association for the Advancement of Science (AAAS) emphasized today. (2000-02-07)

First genetic toggle switch engineered at Boston University
The first-ever (2000-01-18)

Woman pregnant after selecting healthy embryo
Fertility specialists and geneticists at Oregon Health Sciences University in Portland have performed the first successful preimplantation genetic diagnosis (PGD) in the Pacific Northwest. A 39-year old woman is five-months pregnant after selecting a genetically fit embryo through the procedure. (1999-10-28)

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