Current Glioma News and Events

Current Glioma News and Events, Glioma News Articles.
Sort By: Most Relevant | Most Viewed
Page 1 of 11 | 439 Results
Targeted delivery of highly toxic anti-cancer drug to brain tumors
University of Houston biomedical researcher Sheeren Majd is reporting the development and testing of a new nano-carrier as a potential treatment to deliver highly toxic medicine to glioblastomas, the most common and aggressive form of primary brain tumors. (2021-02-23)

Combination treatment for common glioma type shows promise in mice
Gliomas are common brain tumors that comprise about one third of all cancers of the nervous system. In a study funded by the National Institutes of Health (NIH), researchers tested a novel combination treatment approach on mice with tumors with characteristics similar to human astrocytomas and found tumor regression in 60 percent of the mice treated. These encouraging results could be the first step toward developing a treatment for this type of brain cancer. (2021-02-16)

New immunotherapy target discovered for malignant brain tumors
Scientists say they have discovered a potential new target for immunotherapy of malignant brain tumors, which so far have resisted the ground-breaking cancer treatment based on harnessing the body's immune system. The discovery, reported in the journal CELL, emerged from laboratory experiments and has no immediate implications for treating patients. (2021-02-15)

Researchers find parallels in spread of brain cancer in mammals, zebrafish
Virginia Tech scientists have identified a new zebrafish model that could help advance glioblastoma multiforme research. Glioblastoma is an aggressive form of primary brain tumor - fewer than one in 20 patients survive five years after diagnosis. (2021-02-11)

Combination therapy with radiation shows promise in treating glioblastoma
In a study of mice, researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new approach that combines an anti-psychotic drug, a statin used to lower high cholesterol levels, and radiation to improve the overall survival in mice with glioblastoma (2021-02-09)

Aging-US: PAM (PIK3/AKT/mTOR) signaling in glia: potential contributions to brain tumors
'The consideration of aberrant PIK3/AKT/mTOR signaling in glia during aging elucidates several therapeutic opportunities for brain tumors'. (2021-01-25)

New approach emerges to better classify, treat brain tumors
A look at RNA tells us what our genes are telling our cells to do, and scientists say looking directly at the RNA of brain tumor cells appears to provide objective, efficient evidence to better classify a tumor and the most effective treatments. (2021-01-19)

Study identifies exposure to common food-borne pathogen linked to rare brain cancer
A new study suggests a link between toxoplasma gondii (T. gondii) infection and the risk of glioma, a type of brain cancer, in adults. (2021-01-11)

Eavesdropping on the pH levels inside the brain
Researchers at Tohoku University have developed the first all-in-one miniature pH probe for real-time investigations of intrinsic extracellular pH dynamics in the deep brain structures. (2020-12-23)

New guidelines for treating the complications of brain tumours
Experts from the leading oncology societies ESMO (European Society for Medical Oncology) and EANO (European Association of Neuro-Oncology) hav now compiled international guidelines and standards for the treatment of complications of brain tumours (2020-12-09)

Genomic analysis of mako shark reveals genes relating to tumor suppression in humans
Genetic mapping of the shark's liver and eye tissue showed overexpression of nine genes known for action in tumor suppression, wound healing, and probable monochrome vision. The species is considered globally endangered and caught on a large scale by industrial fishing vessels. (2020-12-01)

First large-scale proteogenomic analysis offers insights into pediatric brain tumors
A comprehensive ''proteogenomic'' analysis of the proteins, genes, and RNA transcription involved in pediatric brain tumors has yielded a more complete understanding of these tumors, which are the leading cause of cancer-related deaths in children. The results could help physicians more accurately identify different types of tumors and methods for treating them. (2020-11-25)

Next generation BRAF inhibitor cancer drug shows promise in early patient trial
A new drug designed to work on cancers with an altered BRAF gene has shown promise in an early patient trial presented at the 32nd EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics, which is taking place online. (2020-10-25)

Tumor DNA in spinal fluid could help doctors better monitor childhood brain cancer
Researchers have demonstrated that a new liquid biopsy approach overcomes traditional barriers to quickly and efficiently diagnose and monitor high-grade pediatric gliomas. (2020-10-21)

Experimental glioblastoma therapy shows curative powers in mice models
Houston Methodist researchers used a second-generation prodrug called MP-Pt(IV) to target the deadly cells of glioblastoma tumors and found mice harboring human glioblastoma tumors in their brains had greatly enhanced survival and weight gain when given the newly developed prodrug. This mitochondrial-targeted prodrug also greatly improves outcomes when coupled with standard therapies of radiation and/or chemotherapy. The study was published Oct. 8 in Molecular Cancer Therapeutics. (2020-10-08)

Long sick leave after low-grade brain tumor
One year after the diagnosis of low-grade malignant brain tumor, a University of Gothenburg study shows, just under three people in ten were in full-time employment. Another year later, the proportion remained below half. For this young patient group, returning to work is a key health factor. (2020-09-02)

Genomic analysis predicts survival benefit of adjuvant chemotherapy following radiotherapy over radiotherapy alone in low-grade gliomas in NRG Oncology clinical trial
A practice-changing study, NRG Oncology clinical trial NRG-RTOG 9802, has demonstrated, for the first time, a survival benefit of adjuvant chemotherapy following radiotherapy over radiotherapy alone in certain subgroups of patients with high-risk, low-grade glioma (WHO classification: LGG, grade II), a type of brain tumor that originates from glial cells. (2020-08-31)

Gene targeting helps overcome the resistance of brain cancer to therapy
New insight into a gene that controls energy production in cancer stem cells could help in the search for a more effective treatment for glioblastoma. A McGill-led study published in Nature Communication reveals that suppressing the OSMR gene can improve the effectiveness of radiation therapy. (2020-08-17)

A research team of the CNIO and the HKUST identifies how some gliomas develop chemoresistance
* Patients with glioma - a very common type of tumour originating in the brain - see improvement in survival rates with combined treatment of radiotherapy plus temozolomide * Researchers found a novel mechanism on how tumours evade chemotherapy through genomic rearrangements of the MGMT DNA repair gene * This finding is potentially relevant for updating the methods used to monitor temozolomide efficacy. Genomic rearrangement could be a marker to be detected in blood samples and help make therapeutic decisions (2020-08-04)

Unexpected associations found between drug response and cell changes in brain cancer
Therapies for treating glioblastoma brain cancer can be delivered with greater precision and existing drugs can be used in new ways. These are the conclusions from a study from Uppsala University investigating a large number of cell samples from patients with brain tumours. The researchers have characterised how changes in glioblastoma cells influence the effect of different drugs. Their findings are published in the journal Cell Reports. (2020-07-14)

New treatment strategy may benefit patients with brain cancer
A team led by investigators at Massachusetts General Hospital has uncovered a potentially promising strategy to treat gliomas with mutations in the IDH genes. (2020-06-30)

Artificial intelligence enhances brain tumour diagnosis
A new machine learning approach classifies a common type of brain tumour into low or high grades with almost 98% accuracy, researchers report in the journal IEEE Access. Scientists in India and Japan, including from Kyoto University's Institute for Integrated Cell-Material Sciences (iCeMS), developed the method to help clinicians choose the most effective treatment strategy for individual patients. (2020-06-09)

New targets for childhood brain tumors identified
People with the genetic condition neurofibromatosis type 1 (NF1) are prone to developing tumors on nervous system tissue. A new study from Washington University School of Medicine in St. Louis has found that the development and growth of such tumors are driven by nearby noncancerous neurons and immune cells. The findings point to potential new therapeutic targets for people with NF1. (2020-05-01)

AI may help brain cancer patients avoid biopsy
Brain cancer patients in the coming years may not need to go under the knife to help doctors determine the best treatment for their tumors. (2020-04-21)

Study reveals how 'hypermutated' malignant brain tumors escape chemotherapy and immunotherapy
An analysis of more than 10,000 gliomas and clinical outcomes reported in Nature by scientists in Boston and Paris found that glioma patients whose tumors were hypermutated actually had no significant benefit when treated with checkpoint blockers. (2020-04-15)

Mouse study shows how advancing glioma cells scramble brain function, blood flow
The first sign of trouble for a patient with a growing brain tumor is often a seizure. Such seizures have long been considered a side effect of the tumor. But now a joint team of Columbia engineers and cancer researchers studying brain tumors has found evidence that the seizures caused by an enlarging tumor could spur its deadly progression. (2020-04-14)

New findings shed light on selective therapeutics for IDH1-mutated glioma
Findings of a new study led by Prof. XU Guowang from the Dalian Institute of Chemical Physics (DICP) of the Chinese Academy of Sciences and Prof. YANG Chunzhang from the National Cancer Institute shed light on the selective therapeutics for IDH1-mutated glioma by targeting glutathione synthesis pathway. (2020-04-13)

Virginia Tech scientists reveal brain tumors impact normally helpful cells
Unprovoked recurrent seizures are a serious problem affecting most patients who suffer from glioma, a primary brain tumor composed of malignant glial cells. Fralin Biomedical Research Institute researchers tested the hypothesis that glioma-induces processes that renders a type of brain cells dysfunctional, perpetuating the imbalance between excitation and inhibition in tumor-associated epilepsy. (2020-04-06)

Babies with brain tumors could benefit from targeted treatment
Brain cancer in infants is biologically distinct from other childhood brain tumors and could be successfully treated with targeted drugs, a new study has shown. In the largest and most comprehensive study of infant gliomas to date, scientists found that these tumors are molecularly different from those in older children, helping explain why they tend to be less aggressive. (2020-04-01)

Good news for NF patients with low grade glioma (LGG)
A paper published in the academic journal Neuro-Oncology by NF experts has demonstrated an increased understanding of low grade gliomas (LGG) occurring in children and adults with NF1. (2020-03-31)

Surveillance after surgery does not improve outcomes for patients with glioblastoma
A retrospective study from the University of Missouri School of Medicine and MU Health Care showed patients who underwent surveillance imaging after surgery for brain tumor resection did not have better outcomes than patients who did not have imaging and returned when they felt symptoms of recurrence. (2020-02-26)

Combination drug therapy for childhood brain tumors shows promise in laboratory models
In experiments with human cells and mice, researchers at the Johns Hopkins Kimmel Cancer Center report evidence that combining the experimental cancer medication TAK228 (also called sapanisertib) with an existing anti-cancer drug called trametinib may be more effective than either drug alone in decreasing the growth of pediatric low-grade gliomas. (2020-02-17)

Finding a cure for Fido's brain cancer may help us find a cure for ourselves
For cancers such as glioma, preclinical research models have failed to provide sufficient insight for medical progress. A team led by Jackson Laboratory's Roel Verhaak thoroughly analyzed sporadic canine gliomas and found that their molecular characteristics, including gene mutations and duplications, resemble those of humans. The results indicate that dogs provide an effective model for human gliomas, and learning how to more effectively treat our pets will likely inform better prognoses for human patients. (2020-02-10)

Computer simulation for understanding brain cancer growth
Scientists have developed a computer simulation, BioDynaMo that can be used on standard laptops or desktop computers and provides a software platform which can be used to easily create, run and visualise 3D agent-based biological simulations for brain cancers. (2020-02-06)

Poliovirus therapy shows potential as cancer vaccine in lab studies
A modified form of poliovirus, pioneered at Duke Cancer Institute as a therapy for glioblastoma brain tumors, appears in laboratory studies to also have applicability for pediatric brain tumors when used as part of a cancer vaccine. (2020-01-30)

Brain tumors remodel neuronal synapses to promote growth
Scientists discovered that glioma, a lethal form of brain cancer, alters the activity of neighboring neurons, accelerating a vicious cycle that drives tumor-associated epilepsy and tumor progression. (2020-01-29)

Study uncovers unexpected connection between gliomas, neurodegenerative diseases
New basic science and clinical research identifies TAU, the same protein studied in the development of Alzheimer's, as a biomarker for glioma development. (2020-01-22)

Peering into the genome of brain tumor
Scientists at Osaka University have created a machine learning method for classifying the mutations of glioma brain tumors based on MR images alone. Thus far, classification has only been possible by tissue sampling during surgery. The new method is noninvasive, may remove the need for a tissue sample and help accelerate delivery of treatment for patients. (2020-01-09)

Exploring drug repurposing to treat glioblastoma
MALT1 blockers have long been in clinical use for the treatment of blood cancers. A study suggests that these drugs could potentially also be developed as a treatment option for glioblastoma, the most common and lethal type of brain tumor. (2019-11-27)

Scientists find promising drug combination against lethal childhood brain cancers
Researchers have devised a new, promising plan of attack against deadly childhood brain cancers called diffuse midline gliomas (DMG). NCATS and Stanford University scientists and their colleagues showed that combining two drugs killed DMG patient cells grown in the laboratory and in animal models. The drugs countered the effects of a genetic mutation that causes the diseases. Their studies also uncovered an unrecognized vulnerability in the cancer cells that scientists may be able to exploit. (2019-11-20)

Page 1 of 11 | 439 Results
   First   Previous   Next      Last   
Brightsurf.com is a participant in the Amazon Services LLC Associates Program, an affiliate advertising program designed to provide a means for sites to earn advertising fees by advertising and linking to Amazon.com.