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Current Glucose Levels News and Events, Glucose Levels News Articles.
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Synthesis and functional evaluation of novel aldose reductase inhibitors
Diabetes mellitus (DM) is probably one of the oldest known diseases and the incidence has been increasing steadily all over the world. The etiopathology is very complex and is closely related with long-term damage, dysfunction, and failure of various organs, such as the eyes, kidneys, nerves, heart, and blood vessels. (2017-04-14)

Timely augmentation to triple oral antihyperglycemic therapy
A multicentre, randomized, controlled clinical trial called 'STRATEGY study' which enrolled 5535 type 2 diabetic patients from 237 centers across China, shows that the addition of a third oral antihyperglycemic drug led to a further 0.59% HbA1c reduction and resulted in a 62.3% HbA1c target achievement rate for the entire study. Timely augmentation to triple oral antihyperglycemic therapy could provide a valid choice to overcome 'clinical inertia' and optimize glycemic control in type 2 diabetes. (2017-04-12)

Metabolic mechanism identified for R-LA induced cell death in liver cancer cells
A new study that measured metabolite levels over time in starved rat liver cancer cells showed that treatment with a form of alpha-lipoic acid (LA) inhibited glucose uptake and glycolysis, and led to decreased cellular glucose production from non-carbohydrate sources, which may help explain how the naturally occurring R enantiomeric form of LA (R-LA) promotes the death of hepatoma cells. (2017-04-11)

Intestinal bacteria may protect against diabetes
A high concentration of indolepropionic acid in the serum protects against type 2 diabetes, shows a new study from the University of Eastern Finland. Indolepropionic acid is a metabolite produced by intestinal bacteria, and its production is boosted by a fibre-rich diet. According to the researchers, the discovery provides additional insight into the role of intestinal bacteria in the interplay between diet, metabolism and health. (2017-04-11)

Gene analysis adds layers to understanding how our livers function
In a study reported recently in Nature, Weizmann Institute of Science researchers showed that the liver's amazing multitasking capacity is due at least in part to a clever division of labor among its cells. (2017-04-09)

Risks of diabetics fasting during Ramadan: Hypoglycemia rates w insulin pump v. injections
A new study examining the risk of fasting during Ramadan for people with type 1 diabetes compared blood glucose control and the rates of hypoglycemia and hyperglycemia between users of insulin pump therapy versus multiple daily insulin injections. (2017-04-07)

High-intensity interval training rapidly improves diabetics' glucose metabolism
New research reveals that high-intensity interval training (HIIT) increases glucose metabolism in muscles as well as insulin sensitivity in type 2 diabetes. Already after a two-week training period, the glucose uptake in thigh muscles returned to a normal level. (2017-04-07)

High fat, high sugar diet during pregnancy 'programs' for health complications
Eating a high-fat, high-sugar diet when pregnant 'programs' both mother and child for potential health complications later in life by disrupting metabolic processes within the mother's body, researchers have found. The study is the first to reveal the mechanisms which cause the link between eating an obesity-promoting diet during pregnancy and an increased risk of problems such as type 2 diabetes, obesity and hypertension in both parent and child. (2017-04-05)

Chemical sensor on the basis of materials possessing molecular memory created
Scientists from the Faculty of Chemistry of the Lomonosov Moscow State University have elaborated an electrochemical sensor on the basis of polymers with molecular imprinting, aimed at detection of saccharides and hydroxy acids. (2017-04-05)

Omega-3 fatty acid supplementation may treat autoimmunity in type 1 diabetes
In this issue of the JCI, researchers in Allan Zhao's lab at Guangdong University of Technology determined that dietary supplementation with omega-3 polyunsaturated fatty acids can diminish the inflammatory processes that contribute to development of type I diabetes. (2017-04-04)

Drugs widely used in cancer therapy increase toxicity of chemotherapy in mice
A short-term fast appears to counteract increases in blood sugar caused by common cancer drugs and protect healthy cells in mice from becoming too vulnerable to chemotherapy, according to new research from the University of Southern California. (2017-04-04)

New type of insulin-producing cell discovered
In people with type I diabetes, insulin-producing beta cells in the pancreas die and are not replaced. Without these cells, the body loses the ability to control blood glucose. Researchers at UC Davis have now discovered a possible new route to regenerating beta cells, giving insight into the basic mechanisms behind healthy metabolism and diabetes. Eventually, such research could lead to better treatment or cures for diabetes. (2017-04-04)

Disrupted stress hormone signals in bone cells protect from diet-induced obesity
A high-calorie diet, even without a high amount of fat, causes bone loss, and both high-calorie and high-fat diets induce excessive fat gain and insulin resistance, a new study conducted in mice finds. Study results, to be presented Tuesday at ENDO 2017, the Endocrine Society's 99th annual meeting in Orlando, Fla., found that some of these negative effects happened because of an increase in the actions of glucocorticoids, or stress hormones, in the skeleton. (2017-04-04)

Children at risk of diabetes should be screened by HbA1C, oral glucose tolerance tests
Doctors should add an oral glucose tolerance test (OGTT) to their hemoglobin A1C (HbA1C) when they screen high-risk children for prediabetes and diabetes, new research from South Korea suggests. The study results will be presented Tuesday, April 4, at ENDO 2017, the annual scientific meeting of the Endocrine Society, in Orlando, Fla. (2017-04-04)

Bio-sensing contact lens could someday measure blood glucose, other bodily functions
Transparent biosensors embedded into contact lenses could soon allow doctors and patients to monitor blood glucose levels and a host of other telltale signs of disease without invasive tests. Scientists say the bio-sensing lenses also could potentially be used to track drug use or serve an early detection system for cancer and other serious medical conditions. The researchers will present their work today at the 253rd National Meeting & Exposition of the American Chemical Society. (2017-04-04)

Diabetes control is more difficult for night-shift workers
People with type 2 diabetes have poorer control over their blood glucose levels when they work the night shift compared with those who work in the daytime or are unemployed, a new study finds. The study results, to be presented Monday at the Endocrine Society's 99th annual meeting in Orlando, Fla., showed that poor long-term glycemic, or blood sugar, control, was independent of what workers ate or any sleep problems they had. (2017-04-03)

New simple tool can help identify people at high risk for prediabetes
The time to maximal sugar level during an oral glucose tolerance test is associated with higher risk for prediabetes and could give important information about the ability of the pancreas to secrete insulin, according to research presented at the Endocrine Society's 99th annual meeting, ENDO 2017, in Orlando, Fla. This simple tool could help to identify people who may benefit from early treatment strategies. (2017-04-03)

Artificial pancreas improves blood sugar control in young kids
An artificial pancreas, which delivers insulin in an automated way to individuals with type 1 diabetes, appears to be safe and effective for use in children ages 5 to 8 years, a new study finds. Results will be presented Tuesday at the Endocrine Society's 99th annual meeting in Orlando, Fla. (2017-04-03)

Low-calorie sweeteners promote fat accumulation in human fat
Low-calorie, artificial sweeteners appear to play havoc with the body's metabolism, and large consumption of these sugar substitutes could promote fat accumulation, especially in people who are already obese, preliminary research suggests. The study results will be presented Monday at ENDO 2017, the Endocrine Society's 99th annual meeting in Orlando, Fla. (2017-04-03)

Magnetic brain stimulation causes weight loss by making gut bacteria healthier
A new study finds that a noninvasive electromagnetic brain stimulation technique helps obese people lose weight, partly by changing the composition of their intestinal bacteria -- the so-called gut microbiota. Results of the technique, called deep transcranial magnetic stimulation (dTMS), will be presented Sunday at ENDO 2017, the Endocrine Society's 99th annual meeting in Orlando, Fla. (2017-04-03)

Alcohol abuse even before pregnancy may harm offspring
Mothers who binge drink before they become pregnant may be more likely to have children with high blood sugar and other changes in glucose function that increase their risk of developing diabetes as adults, according to a new study conducted in rats. The results will be presented Sunday at the Endocrine Society's 99th annual meeting in Orlando, Fla. (2017-04-02)

Why does the same exercise exert effects on individuals differently?
Selenoprotein P, a kind of hepatokine hormone secreted from the liver, has been found, through experiments with cultured muscle cells and mice and through clinical studies, to cause pathology named 'exercise resistance,' which prevents health promotion by physical exercise. The present results elucidate one of the reasons why individual responsiveness to exercise differs markedly as well as shed lights on development of therapy for lifestyle diseases due to lack of exercise, obesity and type-2 diabetes. (2017-03-28)

ACP issues recommendations to prevent and treat substance use disorders
Internists say substance use disorders related to illicit and prescription drugs, including opioids, are chronic medical conditions treatable through public and individual health interventions. (2017-03-27)

Scientists discover new class of anti-diabetes compounds that reduce liver glucose production
A team of scientists from the Florida campus of The Scripps Research Institute (TSRI), Dana-Farber Cancer Institute, Harvard Medical School and the Yale University School of Medicine, among others, have identified a new class of compounds that reduce production of glucose in the liver. (2017-03-27)

A little vigorous exercise may help boost kids' cardiometabolic health
As little as 10 minutes a day of high-intensity physical activity could help some children reduce their risk of developing heart problems and metabolic diseases such as diabetes, according to an international study led by a researcher at Wake Forest Baptist Medical Center. (2017-03-24)

Insulin resistance may lead to faster cognitive decline
A new Tel Aviv University study published in the Journal of Alzheimer's Disease finds that insulin resistance, caused in part by obesity and physical inactivity, is also linked to a more rapid decline in cognitive performance. According to the research, both diabetic and non-diabetic subjects with insulin resistance experienced accelerated cognitive decline in executive function and memory. (2017-03-23)

Insulin resistance may lead to faster cognitive decline
A new Tel Aviv University study finds that insulin resistance, caused in part by obesity and physical inactivity, is also linked to a more rapid decline in cognitive performance. (2017-03-21)

Growing global temperatures could be contributing to rising diabetic numbers
Rising temperatures across the world may be playing a part in the growing numbers of people developing diabetes, suggests research published online in the journal BMJ Open Diabetes Research & Care. (2017-03-20)

Critical Path Institute launches type 1 diabetes consortium
C-Path is pleased to announce the launch of the Type 1 Diabetes (T1D) Consortium, funded by the Helmsley Charitable Trust, Janssen R&D, JDRF, and Sanofi. Working collaboratively with INNODIA, a consortium under the Innovative Medicines Initiative, the T1D Consortium will work to qualify islet autoimmunity antibodies as prognostic biomarkers. The biomarkers of interest include (Pro)-insulin autoantibody (IAA), Glutamic acid decarboxylase 65 (GAD65) autoantibody, Islet antigen 2 (IA-2) autoantibody, and Zinc transporter 8 (ZnT8) autoantibody. (2017-03-20)

The Lancet: Indigenous South American group has healthiest arteries of all populations yet studied, providing clues to healthy lifestyle
The Tsimane people -- a forager-horticulturalist population of the Bolivian Amazon -- have the lowest reported levels of vascular ageing for any population, with coronary atherosclerosis (hardening of the arteries) being five times less common than in the US, according to a study published in The Lancet and being presented at the American College of Cardiology conference. (2017-03-17)

Fat cells step in to help liver during fasting
How do mammals keep two biologically crucial metabolites in balance during times when they are feeding, sleeping, and fasting? The answer may require rewriting some textbooks. (2017-03-16)

Intensive medical treatment can reverse type 2 diabetes
Type 2 diabetes can be reversed with intensive medical treatment using oral medications, insulin and lifestyle therapies, according to a study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2017-03-15)

3+ hours daily screen time linked to diabetes risk factors for kids
Daily screen time of three or more hours is linked to several risk factors associated with the development of diabetes in children, finds research published online in the Archives of Disease in Childhood. (2017-03-13)

Convenient and easy to use glucose monitoring and maintenance
A research group from the Center for Nanoparticle Research within the Institute for Basic Science has developed a convenient and accurate sweat-based glucose monitoring and maintenance device. (2017-03-12)

Castration-resistant prostate cancer cell growth impeded by endostatin
Researchers have discovered that endostatin, a naturally occurring protein in humans, can significantly decrease proliferation of castration-resistant prostate cells in culture, and in a recent paper in The FASEB Journal, they describe the physiological pathways and signaling evoked by endostatin. This endostatin effect is now being tested in a preclinical xenograft animal model of castration-resistant prostate cancer. (2017-03-10)

University of Alberta research may provide solutions for the future treatment of diabetes
In a study published in the journal Diabetes, researchers at the University of Alberta found that feeding resveratrol to obese mice over a period of 6 weeks altered the makeup of the bacteria in their intestines, improving glucose tolerance. A second experiment, involving fecal transplant from resveratrol fed mice to obese mice with insulin resistance, led to much more dramatic and rapid effects. (2017-03-09)

Men with impaired glucose metabolism should avoid high-carbohydrate foods in the evening
According to a nutrition study led by the German Institute of Human Nutrition, the so-called internal clock also influences how people with impaired glucose metabolism react to carbohydrate-rich food. E.g., in men with prediabetes, abundant consumption of foods containing starch and sugar in the evening had a negative effect on their blood glucose regulation. In comparison, in healthy study participants the timing of carbohydrate intake did not play a significant role in blood glucose regulation. (2017-03-09)

Bone-derived hormone suppresses appetite in mice
Researchers at Columbia University Medical Center discovered that lipocalin 2, a hormone secreted by bone cells, suppresses appetite in mice. The study findings, which reveal a new mechanism for regulating food intake and blood sugar, could lead to the development of new treatments for obesity, type 2 diabetes, and other metabolic disorders. (2017-03-08)

Nurses central to getting diabetes care off to a better start
Giving primary health care nurses a greater role in managing Type 2 Diabetes can significantly reduce delays in starting insulin treatment, a team of researchers led by the University of Melbourne has found.  (2017-03-08)

How rare sugars might help control blood glucose
In an era when the label 'natural' hits a sweet spot with consumers, some uncommon sugars emerging on the market could live up to the connotation. Preliminary animal studies have suggested that allulose and other low-calorie, natural rare sugars could help regulate glucose levels. Now, researchers are investigating how they might exert such effects. They report their findings in ACS' Journal of Agricultural and Food Chemistry. (2017-03-08)

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