Current Glucose News and Events

Current Glucose News and Events, Glucose News Articles.
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Pancreatic β cell-derived exosomal miR-29 family enhances hepatic glucose output
In a new study published in Journal of Extracellular Vesicles, Chen-Yu Zhang's group at Nanjing University, School of Life Sciences, and Antonio Vidal-Puig's group at University of Cambridge report that pancreatic β cells secrete miR-29 family members (miR-29s) via exosomes in response to high levels of free fatty acids (FFAs). Theses β cell-derived exosomal miR-29s regulate glucose homeostasis through their manipulations on glucose output in liver. (2021-01-22)

Sloan Kettering Institute scientists solve a 100-year-old mystery about cancer
A long-standing mystery is why fast-growing cells, like cancer cells and immune cells, rely on a seemingly inefficient form of metabolizing glucose to power their activities. In a new study, scientists at the Sloan Kettering Institute offer a compelling solution. (2021-01-21)

NIH study compares low-fat, plant-based diet to low-carb, animal-based diet
People on a low-fat, plant-based diet ate fewer daily calories but had higher insulin and blood glucose levels, compared to when they ate a low-carbohydrate, animal-based diet, according to a small but highly controlled study at the National Institutes of Health. Led by researchers at the National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), the study compared the effects of the two diets on calorie intake, hormone levels, body weight, and more. (2021-01-19)

Moffitt researchers identify how cancer cells adapt to survive harsh tumor microenvironments
To better understand the conditions that select for the Warburg Effect and the mechanisms where cells can express this metabolic adaptation, Moffitt researchers subjected nonmalignant cells to the harsh tumor microenvironment that is present during early carcinogenesis, known as ductal carcinoma in situ. In a new research article published in the Proceedings of the National Academy of Sciences, the Moffitt team shows that these conditions select for cells to express a Warburg Effect. (2021-01-19)

Better diet and glucose uptake in the brain lead to longer life in fruit flies
Researchers from Tokyo Metropolitan University have discovered that fruit flies with genetic modifications to enhance glucose uptake have significantly longer lifespans. Looking at the brain cells of aging flies, they found that better glucose uptake compensates for age-related deterioration in motor functions, and led to longer life. The effect was more pronounced when coupled with dietary restrictions. This suggests healthier eating plus improved glucose uptake in the brain might lead to enhanced lifespans. (2021-01-16)

ADA lowers target HbA1C levels for children with type-1 diabetes
In early 2020, upon recommendation by leading endocrinologists, American Diabetes Association lowered the target hemoglobin A1C guidelines for children with type 1 diabetes. Their goal in recommending stricter glucose control was to ensure children with type 1 diabetes have better immediate and long-term health outcomes with fewer health complications and reduced mortality rates. In this ''Perspective'' article they discuss the evidence and rationale behind this new recommendation. (2021-01-14)

Same difference: predicting divergent paths of genetically identical cells
DALLAS - Jan. 11, 2021 - A set of biomarkers not traditionally associated with cell fate can accurately predict how genetically identical cells behave differently under stress, according to a UT Southwestern study. The findings, published by Cell Reports as a Dec. 1 cover story, could eventually lead to more predictable responses to pharmaceutical treatments. (2021-01-11)

Surrey unveils breakthrough manufacturing process of ultra-thin sensor for smart contact lenses
Smart contact lenses could soon become mainstream thanks to a new manufacturing process that has allowed the University of Surrey to develop a multifunctional ultra-thin sensor layer. (2021-01-06)

Research shows a few beneficial organisms could play key role in treating type 2 diabetes
Researchers have found that a few organisms in the gut microbiome play a key role in type 2 diabetes, opening the door to possible probiotic treatments for a serious metabolic disease affecting roughly one in 10 Americans. (2021-01-04)

Study of 50,000 people finds brown fat may protect against numerous chronic diseases
By far the largest of its kind in humans, the study confirms and expands the health benefits of brown fat suggested by previous research. (2021-01-04)

Common diabetes drug may trigger rare complications for COVID-19 patients
An uptick in a particular type of DKA called euDKA at Brigham and Women's Hospital during the COVID-19 pandemic has led researchers to hypothesize that diabetes patients on glucose-lowering drugs may be at increased risk for euDKA when they contract COVID-19. The observational case series was published in The American Association of Clinical Endocrinologists Clinical Case Reports. (2020-12-24)

New research highlights the importance of the thymus in successful pregnancies
How the immune system adapts to pregnancies has puzzled scientists for decades. Now, findings from an international group of researchers, led by researchers at Karolinska Institutet in Sweden, reveal important changes that occur in the thymus to prevent miscarriages and gestational diabetes. The results are published in the journal Nature. (2020-12-23)

New research highlights the importance of a forgotten organ in ensuring healthy pregnancies
An international research team led by UBC has uncovered for the first time the importance of a small gland tucked behind the sternum that works to prevent miscarriage and diabetes in pregnant women. (2020-12-23)

The thymus as key to healthy pregnancies
How the immune system adapts to pregnancy has puzzled researchers for decades. An international team of researchers, including scientists from IMBA (Institute of Molecular Biotechnology) of the Austrian Academy of Sciences has now discovered that important changes in the thymus occur in order to prevent miscarriages and gestational diabetes. The results are published in the journal Nature. (2020-12-23)

New drug combination could improve glucose and weight control in diabetes
Scientists have shown that adding an experimental cancer drug to a widely used diabetes treatment improves blood glucose control and weight loss in mice, according to a study published today in eLife. (2020-12-22)

New discovery opens novel pathway for high-titer production of drop-in biofuels
Using an unusual, light-dependent enzyme and a newly discovered enzymatic mechanism, researchers from Aarhus University and Massachusetts Institute of Technology have enabled the biological synthesis of high-yield industry relevant production of climate neutral drop-in fuels from biowaste. The study along with the new discovery has been published in Nature Communications. (2020-12-17)

CAN risk in diabetes reduced with intensive control of blood glucose and blood pressure
Cardiovascular autonomic neuropathy (CAN), a frequent but underdiagnosed complication of diabetes that can be life-threatening. Researchers found that intensive glycemic control reduced CAN risk by 17%, while intensive blood pressure control reduced risks by 22%. (2020-12-16)

Proteins enable crop-infecting fungi to 'smell' food
New UC Riverside research shows the same proteins that enable human senses such as smell also allow certain fungi to sense something they can eat. (2020-12-15)

Different forms of sugar impact hunger-suppressing hormones in young adults
Drinks with sucrose compared to glucose may cause young adults to produce lower levels of appetite-regulating hormones, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2020-12-10)

Hydrogels with fine-toothed molecular combs may make enduring glucose-monitoring implants
In a new study, published online in the journal American Chemical Society (ACS) Applied Polymer Materials, scientists at Texas A&M University reported they have designed a hydrogel membrane that may be used to house optical glucose sensing materials, toward building a biosensor for monitoring sugar levels in diabetics. (2020-12-09)

How poor oral hygiene may result in metabolic syndrome
Researchers from TMDU identified a novel mechanism by which periodontal disease may cause metabolic syndrome. By studying patients with metabolic syndrome, the researchers demonstrated high antibody titers against Porphyromonas gingivalis, the bacterium causing periodontal disease. In a mouse model, the researchers then showed that infection with this bacterium causes systemic insulin resistance and metabolic dysfunction in skeletal muscle by altering the gut microbiome. This study shows the effect periodontal disease can have on the entire body. (2020-12-08)

Researchers use genomics to identify diabetic retinopathy factors
In the paper, ''Integration of genomics and transcriptomics predicts diabetic retinopathy susceptibility genes,'' published in eLife, researchers identified genes that respond differently in response to high glucose in individuals with and without diabetic retinopathy. (2020-12-07)

Findings about cilia on cells of the vessel wall may be relevant for diabetes treatment
A new study from Karolinska Institutet and the Helmholtz Diabetes Research Center shows that primary cilia, hair-like protrusions on endothelial cells inside vessels, play an important role in the blood supply and delivery of glucose to the insulin-producing beta cells in the pancreatic islets. The findings are published in eLife and may be relevant for transplantation therapies in diabetes, as formation of functional blood vessels is important for the treatment to be successful. (2020-12-04)

Blackcurrants are favorable for glucose metabolism
Blackcurrants have a beneficial effect on post-meal glucose response, and the required portion size is much smaller than previously thought, a new study from the University of Eastern Finland shows. (2020-12-03)

Self-repairing gelatin-based film could be a smart move for electronics
Dropping a cell phone can sometimes cause superficial cracks to appear. But other times, the device can stop working altogether because fractures develop in the material that stores data. Now, researchers reporting in ACS Applied Polymer Materials have made an environmentally friendly, gelatin-based film that can repair itself multiple times and still maintain the electronic signals needed to access a device's data. The material could be used someday in smart electronics and health-monitoring devices. (2020-12-02)

'Artificial Pancreas Dashboard' to standardize hybrid closed-loop reporting
A standardized ''Artificial Pancreas (AP) Dashboard'' should provide easy to use single-page hybrid closed-loop system (HCL) reporting for insulin requiring patients with diabetes. The AP Dashboard will help standardize HCL reporting similar to standardized CGM reporting and an electrocardiogram (EKG) and will be likely to help improve glycemic control and reduce hypoglycemia. (2020-12-01)

Obesity changes cell response to glucose, uses slower metabolic path in mouse liver
Healthy cells and cells with Type 2 diabetes use completely different pathways to manage blood sugar levels, according to results from a study in mice. Researchers used a trans-omic approach, combining data from genes (transcriptomics) and metabolites (metabolomics) to identify and connect the many separate processes involved in responding to glucose. Obese mice lack most of the rapid response to glucose found in healthy metabolism, instead relying on much slower methods like changing gene expression. (2020-12-01)

Biodiesel made from discarded cardboard boxes
Dr. Sun-Mi Lee and her team at the Clean Energy Research Center of the Korea Institute of Science and Technology (KIST) have announced that they have developed a novel microorganism capable of producing biodiesel precursors from lignocellulosic biomass such as discarded agricultural by-products, waste paper, and cardboard boxes. This microorganism has achieved the product yield twice of what was obtainable from its predecessors. (2020-11-30)

Protein commonly screened for in pregnancy is linked to gestational diabetes
Laboratory research and analysis of epidemiological data by Silvia Corvera, MD, and Tiffany Moore Simas, MD, MPH, MEd, and colleagues show that low levels of a protein commonly seen in screening tests for chromosomal disorders during the first trimester of pregnancy is associated with adipose tissue remodeling, glucose resistance and gestational diabetes mellitus in pregnant women. (2020-11-30)

Signaling switch in pancreatic β-cells determines anti-diabetic drug effectiveness
An international research group headed by Professor SEINO Susumu (Kobe University Graduate School of Medicine) has clarified the action mechanism of widely utilized incretin-based drugs in the treatment of diabetes. These findings are important for illuminating the mechanism behind diabetes and will hopefully provide a basis for new treatments. (2020-11-25)

Extraction of largely-unexplored bodily fluid could be a new source of biomarkers
Using an array of tiny needles that are almost too small to see, researchers have developed a minimally-invasive technique for sampling a largely-unexplored human bodily fluid that could potentially provide a new source of information for routine clinical monitoring and diagnostic testing. (2020-11-25)

High blood sugar could increase COVID-19 death risk for non-diabetics, says study
Abnormally high blood sugar may worsen outcomes and mortality rates for COVID-19 patients, including those without diabetes, according to major research published in the peer-reviewed open access journal Annals of Medicine. (2020-11-23)

Good long-term effects of continuous glucose monitoring
New data on continuous glucose monitoring for people with type 1 diabetes, over a significantly longer period than before, are now available. A University of Gothenburg study shows that using the CGM tool, with its continuous monitoring of blood sugar (glucose) levels, has favorable effects over several years. (2020-11-16)

Computer vision app allows easier monitoring of diabetes
A computer vision technology developed by University of Cambridge engineers has now been developed into a free mobile phone app for regular monitoring of glucose levels in people with diabetes. (2020-11-13)

Scientists discover secret to superbug's virulence in diabetic infections
The bodies of people with uncontrolled diabetes appear to be the perfect environment for a common type of superbug to thrive unchecked and do its worst damage, according to new research reported today in Science Advances. Staphylococcus aureus -- a bacteria that is often resistant to antibiotics -- thrives in glucose-rich diabetic conditions, which trigger it to activate some of its most virulent features. A lack of insulin prevents the immune system from responding to the infection. (2020-11-13)

In mice, cadmium exposure during pregnancy linked to obesity in female offspring
In a mouse study aimed at modeling human exposure to the toxic metal cadmium, researchers found that female offspring of mice exposed to cadmium during pregnancy became obese in adulthood, developed fatty livers and could not process glucose normally. Male offspring were not affected in the same way. The study also sheds light on how cadmium exposure could affect mitochondrial function and developmental signaling pathways in the liver. (2020-11-12)

A molecule from gut bacteria reduces effect of diabetes medication
The action of metformin, the classic drug used to treat diabetes by stabilizing blood sugar, can be blocked by a molecule from the bacteria in our intestines, a University of Gothenburg study shows. (2020-11-11)

Chemicals in your living room cause diabetes
A new UC Riverside study shows flame retardants found in nearly every American home cause mice to give birth to offspring that become diabetic. (2020-11-10)

Sweet taste reduces appetite?
To date, very little is known about how sweetness perception contributes to satiety. This study, conducted by an Austrian-German team led by chemists Veronika Somoza and Barbara Lieder, provides new insights into the relationship between the sweet taste of sugar, energy intake and the regulatory process of hunger and satiety. The study was published in the journal 'Nutrients'. (2020-11-10)

Diet and lifestyle during pregnancy linked to modifications in infants' DNA
A new study has shown pregnant women with obesity could reduce the health risks for their infants through improved diet and more physical activity. (2020-11-06)

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