Current HIV Infection News and Events | Page 25

Current HIV Infection News and Events, HIV Infection News Articles.
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New insight on potent HIV antibody could improve vaccine design
A new observation, led by researchers at the Duke Human Vaccine Institute, highlights the importance of previously unstudied mutations that arises early in bnAbs, giving the antibodies the flexibility to adapt to changes in the virus's outer envelope protein structure. This flexibility enables the antibody to dock on diverse strains of the virus and more potently neutralize them. (2019-02-20)

Revealed: How the 'Iron Man' of immune cells helps T cells fight infection
The immune system's killer T cells are crucial in fighting viral infections. A fraction of them - memory cells - live on once infection is controlled in order to fight re-infection by the same virus. They are of great interest as the basis of T cell-based vaccination and immunotherapies. Now, scientists has revealed the mechanisms by which other immune cells called 'helper T cells' are able to provide the support needed to keep memory cells functioning optimally. (2019-02-19)

Using anti-cancer immunotherapy to fight HIV
Researchers at the University of Montreal Hospital Research Centre (CRCHUM) have shown that immunotherapy treatments against cancer could reduce the amount of virus that persists in people on triple therapy. In a study published in the journal Nature Communications, they show, in the cells of people living with HIV, how these therapies reveal the virus - until now hidden in the hollows of infected cells - to the immune system. (2019-02-19)

Seeing the unseeable
Researchers at Cardiff University have used X-ray crystallography and computer simulation to get a closer look at how viruses bind cells and cause infection. (2019-02-19)

Cervical microbiome may promote high-grade precancerous lesions
Infections with a Human Papillomavirus (HPV) cause 99 percent of cervical cancer cases, and the disease's first sign is often the appearance of precancerous lesions on a woman's cervix. But bacteria may play an important role, too. New research suggests that the cervical microbiome may influence HPV infection more than researchers previously thought. (2019-02-19)

Prevention, treatment efforts reduce HIV infection among transgender women
Programs to prevent HIV in transgender women are helping to lower the rate of new infection but better care and treatment of this vulnerable population is still needed, especially among those of lower income or people of color, according to a new Rutgers study. (2019-02-18)

Altered data sets can still provide statistical integrity and preserve privacy
Synthetic networks may increase the availability of some data while still protecting individual or institutional privacy, according to a Penn State statistician. (2019-02-16)

New study shows HPV not likely transmittable through the hand
Commonly known as HPV, Human papillomavirus is a virus that infects the skin and genital area, in many cases leading to a variety of genital, anal, and oropharyngeal cancers in men and women. Strong evidence exists showing that penetrative genital sex and oral sex can transmit HPV. However, while HPV is also often detected in the hands, the question of whether hand-genital contacts can transmit HPV has long been a source of debate among researchers. (2019-02-11)

Tracking HIV's ever-evolving genome in effort to prioritize public health resources
Using HIV genetic data, researchers discovered that transgender women in Los Angeles are at higher risk of being in an HIV transmission network than men who have sex with men. In addition, cisgender men in these clusters should be considered at higher risk for HIV than previously thought. (2019-02-11)

Duke-NUS study: Interaction between two immune cell types could be key to better dengue vaccines
A sentinel immune cell in the skin surprises researchers by forming a physical connection with a virus-killing T cell. (2019-02-07)

Study finds HIV+ cancer patients benefit from immunotherapy
The immunotherapy that has revolutionized treatment of many cancers appears to offer similar benefit to cancer patients living with HIV. (2019-02-07)

HPV infection may be behind rise in vocal-cord cancers among young nonsmokers
A Massachusetts General Hospital research team finds evidence that the remarkable recent increase in vocal-cord cancer in young adults appears to be the result of infection with strains of human papilloma virus that also cause cervical cancer and other malignancies. (2019-02-07)

The protective role of dengue immunity on Zika infection in a Brazilian favela
By monitoring the spread of Zika virus through a densely populated Brazilian favela during a 2015 outbreak, researchers have gained new perspectives into the outbreaks of this virus in the Americas in recent years. (2019-02-07)

Dengue immunity may buffer against Zika, study finds
Research conducted by a team led by the Brazilian Ministry of Health and including University of Florida epidemiologist Derek Cummings finds that previous infection with dengue reduces one's risk of infection with Zika. (2019-02-07)

Relationship counseling encourages couples HIV testing
It's long been known that couples HIV testing and counseling is an effective way to mutually disclose HIV status and link to health care -- unfortunately, couples don't use it even though it's widely available. (2019-02-07)

Finding clues to a functional HIV cure
George Mason University's Yuntao Wu's research team has identified a measurable indicator that could prove instrumental in the fight against HIV. The research recently published in Science Advances, focuses on cofilin, a key protein that regulates cells to mobilize and fight against infection. HIV patients have ''significantly lower'' levels of cofilin phosphorylation--but by stimulating the T cells with additional therapeutics, researchers could modulate the levels of cofilin activity needed to restore T cell mobility. (2019-02-07)

Researchers find new treatment for Chlamydia
Researchers at the University of Waterloo have developed a new way to prevent and treat Chlamydia, the most common sexually transmitted bacterial infection in the world. (2019-02-06)

HIV drug could treat Alzheimer's, age-associated disorders
Research led by Brown found that blocking retrotransposon activity with a generic HIV/AIDS medication significantly reduces age-related inflammation in old mice and senescent human cells, providing hope for treating age-associated disorders. (2019-02-06)

HIV-1 protein suppresses immune response more broadly than thought
Scientists have revealed how a protein produced by HIV-1 plays a broader role in suppressing the immune system's response to infection than previously thought. (2019-02-05)

How lung tissue forms immune cell hubs in times of need
Research uncovers how lung tissue is remodelled to support an immune response to influenza. The findings hold promise for broader immunisation against flu and the development of new therapeutic strategies for autoimmune diseases. (2019-02-05)

A reservoir of bacteria: sink drains next to toilets in patient rooms may harbor dangerous organisms
Sinks situated next to patient toilets in hospital rooms may be reservoirs for Klebsiella pneumoniae carbapenemase (KPC), increasing the risk of dangerous germ transmission, according to new research published in the American Journal of Infection Control (AJIC), the journal of the Association for Professionals in Infection Control and Epidemiology. (2019-02-05)

Diversity in the CD4 receptor protects chimpanzees from infection by AIDS-like viruses
Hahn's lab and an international team of collaborators, found that the CD4 surface protein, which is used by HIV and SIV as the receptor to enter immune cells, is highly variable among wild chimpanzees. Understanding how these viruses are transmitted within and between species may reveal clues for novel vaccine strategies in humans. (2019-02-04)

SFU researchers find new clues to controlling HIV
An international research team led by Simon Fraser University and South Africa's University of KwaZulu-Natal in South Africa is harnessing the immune system to reveal new clues that may help in efforts to produce an HIV vaccine. They've identified a connection between infection control and how well antiviral T cells respond to diverse HIV sequences. (2019-02-01)

Research identifies pathway connecting some ARV drugs with liver disease
Research out of the University of Kentucky has identified a potential pathway by which certain ARV drugs -- commonly given to patients with HIV -- give rise to liver disease. (2019-01-31)

Introducing nemuri, a protein that induces sleep and fights infection
Researchers have discovered a bacteria-fighting peptide in fruit flies that also promotes sleep after sleep deprivation or infection, according to a new study. (2019-01-31)

HIV hidden in patients' cells can now be accurately measured
Until now, researchers haven't been able to accurately quantify a latent form of HIV that persists in patients' immune cells. A new genetic technique is fast and 10 to 100 times more accurate than previous diagnostics. (2019-01-30)

NIH-supported scientists develop tool to measure success of HIV cure strategies
Scientists funded by the National Institutes of Health have developed a new assay to accurately and easily count the cells that comprise the HIV reservoir, the stubborn obstacle to an HIV cure. This advance will enable researchers who are trying to eliminate the HIV reservoir to clearly understand whether their strategies are working. The research was supported by the National Institute of Allergy and Infectious Diseases (NIAID), part of NIH. (2019-01-30)

USPSTF recommendation statement on prevention of gonococcal eye infections in newborns
The US Preventive Services Task Force (USPSTF) reaffirms its recommendation for the use of an antibiotic ointment to prevent gonococcal eye infections in all newborns, a gonorrhea infection that is transmitted from the mother to the newborn during delivery. (2019-01-29)

Scientists discover an immune 'clock' that controls infections and cardiovascular disease
CNIC researchers have demonstrated the existence of an immune 'clock' that coordinates day/night cycles through the activity of a class of leucocytes called neutrophils. (2019-01-29)

Personalized decision aid did not help surrogates and clinicians agree on treatment goals for critically ill patients
A personalized web-based decision aid did not help surrogate decision makers and clinicians agree on treatment goals for patients on life support for longer than average. Nearly all surrogates chose a more aggressive treatment goal than was suggested by the decision aid, despite the aid being based on the surrogate's report of patient values. Results from a multi-center randomized clinical trial are published in Annals of Internal Medicine. (2019-01-28)

Shiftless: Novel host antiviral factor that inhibits programmed -1 ribosomal frameshifting
GAO Guangxia's group at the Institute of Biophysics of the Chinese Academy of Sciences reported a novel host antiviral factor named Shiftless that inhibits -1PRF. Shiftless displayed considerable inhibitory activity against all the tested -1PRF from both viruses and cellular genes, indicating that it is a broad-spectrum -1PRF inhibitor. (2019-01-27)

Drought in Lesotho heightened HIV risk in girls
Adolescent girls exposed to severe drought conditions in rural Lesotho had higher rates of HIV, according to a new study led by researchers at ICAP at Columbia University, a global health organization based at the Columbia Mailman School of Public Health, and from the Lesotho Ministry of Health and US Centers for Disease Control and Prevention. (2019-01-24)

Possible link between rotavirus vaccine and decline in type 1 diabetes
A drop in the number of young children diagnosed with type 1 diabetes could be associated with the introduction of routine rotavirus vaccination of Australian infants, according to a new study by Melbourne researchers. (2019-01-22)

Dengue virus immunity may protect children from Zika symptoms
Previous infection with dengue virus may protect children from symptomatic Zika, according to a study published Jan. 22 in the open-access journal PLOS Medicine by Eva Harris of the University of California, Berkeley, and colleagues. (2019-01-22)

Children who had a dengue infection could be protected from symptomatic Zika
A prior dengue virus infection could protect children from symptomatic Zika virus infection, according to a study by an international group of researchers including those from the University of Michigan and the University of California, Berkeley. (2019-01-22)

Dengue immunity may be protective against symptomatic Zika, study finds
Children with a history of prior dengue virus infection had a significantly lower risk of being symptomatic when infected by Zika virus, according to a study in Nicaragua of more than 3,000 children aged 2 to 14 years. Experts have worried that prior dengue virus infection could exacerbate severe Zika disease. However, the new findings, published in PLOS Medicine, indicate that prior dengue immunity in children may in fact be protective against symptomatic Zika disease. (2019-01-22)

Secret to sepsis may lie in rare cell
In a paper published in Nature Immunology, scientists from Seattle Children's Research Institute reveal how a rare group of white blood cells called basophils play an important role in the immune response to a bacterial infection, preventing the development of sepsis. Researchers say their findings could lead to better ways to prevent the dangerous immune response that strikes more than 30 million people worldwide every year. (2019-01-21)

Fever boots immune cell trafficking through a thermal sensory Hsp90-α4 integrin pathway
Recently, researchers at the Shanghai Institute of Biochemistry and Cell Biology of the Chinese Academy of Sciences, in collaboration with colleagues, demonstrated that fever promotes T lymphocyte trafficking through heat shock protein 90 (Hsp90)-induced α4 integrin activation and signaling in T cells. (2019-01-17)

Many hepatitis infections go undiagnosed in cancer patients
Results from the largest study of hepatitis B and C and HIV infection prevalence in cancer patients show an alarmingly high rate of undiagnosed acute and chronic hepatitis B and C. Hepatitis B and C are serious but treatable viral infections that cancer patients should know they have - because these viruses can cause life-threatening complications when certain cancer treatments are used. (2019-01-17)

Combination therapy treats leishmaniasis, HIV patients
Coinfection with visceral leishmaniasis (VL) and human immunodeficiency virus (HIV) has been observed in at least 35 countries on four continents and requires special case management. Currently, the World Health Organization recommends AmBisome monotherapy for treatment. Now, researchers reporting in PLOS Neglected Tropical Diseases have showed that a combination therapy of AmBisome and miltefosine is more effective. (2019-01-17)

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