Current HIV Patients News and Events

Current HIV Patients News and Events, HIV Patients News Articles.
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Immune-compromised people with HIV, APOE4 gene may have a compounded risk for Alzheimer's
People living with the human immunodeficiency virus (HIV) who have a history of severe immunosuppression and at least one copy of the Alzheimer's disease-related gene variant APOE4, might see a compounded adverse effect on the circuitry that impacts memory. This could eventually lead to an increased risk for dementia after age 65, according to Georgetown University Medical Center investigators and colleagues. (2021-02-22)

What is COVID-19's impact on Black and Latino persons living with HIV?
Study looks at COVID-19 effects on engagement in HIV care, HIV medication use, and overall well-being among low-income Black and Latino individuals who have lived with HIV for many years. (2021-02-22)

West Virginia's enduring, intertwined epidemics: Opioids and HIV
In a paper for The Lancet, West Virginia University Drs. Sally Hodder and Judith Feinberg state that the opioid and HIV epidemics are intertwined in West Virginia, and therefore should be treated together. (2021-02-22)

To end HIV epidemic, we must address health disparities
despite coordinated national efforts to implement HIV services, the epidemic persists, especially in the South. It also disproportionately impacts marginalized groups, such as Black/African-American and Latinx communities, women, people who use drugs, men who have sex with men, and other sexual and gender minorities. researchers, advocates, and other stakeholders reported on the HIV epidemic response in The Lancet HIV in the USA Series, published online today (https://www.thelancet.com/series/HIVinUSA). (2021-02-19)

The Lancet: USA failing to reach populations most in need of HIV prevention and treatment services as epidemic grows in the South and rural areas
The USA continues to lag behind other G-7 nations when it comes to controlling its HIV epidemic and is the only high-income country among the top 10 most HIV-affected countries worldwide. The majority of HIV infections are now concentrated in the South and rural areas, where women and minorities are disproportionately affected; a disparity that has also been seen in the COVID-19 pandemic which has disproportionately affected African Americans, Latinx Americans, Native Americans, and prisoners and detainees. (2021-02-19)

A new piece of the HIV infection puzzle explored
Researchers from the European Molecular Biology Laboratory and Heidelberg University Hospital combine high-resolution imaging to observe the infection process in cell nuclei, opening the door for new therapeutics. (2021-02-18)

Researchers find diverse supportive partnerships among older gay men with and without HIV
Recent data reveals that gay men living with HIV report having supportive relationships with family, friends, or in informal relationships rather than with primary romantic partners, while gay men who are HIV negative report having relationships mainly with primary partners. Additionally, gay men living with HIV were more likely to report no primary or secondary supportive partnerships compared to men who are HIV negative. (2021-02-17)

Radiomics shows cocaine fuels coronary artery disease risk
Radiomics--the extraction of very detailed quantitative features from medical images--provides a refined understanding of how cocaine use and other risk factors affect the course of coronary artery disease, according to a new study. Researchers said the study shows the power of radiomics to improve understanding of not just cardiovascular disease, but cancer and other conditions as well. (2021-02-16)

Self-testing trebles HIV testing rate amongst trans people in randomised trial
HIV self-testing could reduce the time between HIV infection and HIV diagnosis amongst trans people when compared to standard testing services, suggests new research in EClinicalMedicine. The project was a collaboration between the London School of Hygiene & Tropical Medicine (LSHTM), University College London (UCL), and the Medical Research Council Clinical Trials Unit. It involved more than 100 trans men and trans women in England and Wales, and is the largest HIV self-testing trial in this community to be reported. (2021-02-11)

Researchers find delirium in hospitalized patients linked to mortality, disability
Delirium, a form of acute brain dysfunction, is widespread in critically ill patients in lower resourced hospitals, and the duration of delirium predicted both mortality and disability at six months after discharge, according to a study published in PLOS ONE. (2021-02-11)

New study gives hope of eliminating mother-to-baby transmission of HIV
Anti-retroviral drugs are a vital tool in the prevention and treatment of HIV. A new study of pregnant women in Tanzania shows that life-long antiviral treatment also seems to prevent viral transmission from mother to baby. The results of the study, which was conducted in part by researchers at Karolinska Institutet in Sweden and published in Lancet HIV, make a promising contribution to the WHO's work with HIV prevention in low and middle-income countries. (2021-02-11)

HIV research yields potential drug target
Understanding the mechanism of activation of a protein called SAMHD1 could be a step forward in the fight against HIV/AIDS. ''If we are able to increase SAMHD1 activity using a specific drug, that could potentially have anti-HIV activity,'' said Corey H. Yu, PhD, postdoctoral fellow in the laboratory of Dmitri Ivanov, PhD, at UT Health San Antonio. (2021-02-10)

Universal access to preventive drugs could reduce HIV incidence in sub-Saharan Africa
Universal HIV testing with linkage to treatment and prevention may be a promising approach to accelerate reductions in new infections in generalized epidemic settings, according to a study published February 9th, 2021 in the open-access journal PLOS Medicine by Catherine Koss of the University of California, San Francisco, and colleagues. (2021-02-09)

Racism and anti-gay discrimination heighten risk for arrest and incarceration
New research by Morgan Philbin, PhD, at Columbia University Mailman School of Public Health and colleagues looks at why Black young men who have sex with men (YMSM) are disproportionately subject to high rates of arrest and incarceration. They find that perceived racial discrimination, sexual orientation discrimination, and HIV-status discrimination are all associated with risk for criminal justice involvement in this population. (2021-02-09)

Scientists urge for investment now in highly potent vaccines to prevent the next pandemic
In an article that appears in the journal Nature, Dennis Burton, PhD, and Eric Topol, MD, of Scripps Research call for governments to provide significant funding support for rational vaccine design based on broadly neutralizing antibodies. Such antibodies provide broad-spectrum potency against viruses, a valuable characteristic that opens the door to vaccines that could provide immunity against the many variants that might evolve from a fast-mutating virus. They could also be used as drugs to prevent and treat infections. (2021-02-09)

HIV: an innovative therapeutic breakthrough to optimize the immune system
Prompted by the need to improve conventional treatments for people infected with the human immunodeficiency virus (HIV-1), a team from the Institut national de la recherche scientifique (INRS) has identified a therapeutic approach to restore the effectiveness of immune cells. The study, led by doctoral student Hamza Loucif and Professor Julien van Grevenynghe, was published in the journal Autophagy. (2021-02-08)

Clients of female sex workers should be targeted for HIV prevention and treatment in South Africa
The researchers found that over a ten-year period (2010-19), sex between female sex workers and their paying clients contributed 6.9 per cent of new HIV infections, while sex between clients with their non-paying partners contributed 41.9 per cent (2021-02-04)

Human immune cells have natural alarm system against HIV
Researchers at Washington University School of Medicine in St. Louis have identified a potential way to eradicate the latent HIV infection that lies dormant inside infected immune cells. Studying human immune cells, the researchers showed that such cells have a natural alarm system that detects the activity of a specific HIV protein. Rather than attack the virus based on its appearance, this strategy is to attack the virus based on what it is doing -- vital activities that are required for the virus to exist. (2021-02-04)

New study examines addiction medicine treatment in Vietnam
A study published in The Lancet HIV marks one of the first scientifically robust assessments of a new model of treating HIV in lower or middle income countries where injection drug use is a major cause of HIV infection. It also suggests the importance of building support for peer and community connections to tackle the opioid epidemic that continues to ravage the United States in the midst of the COVID-19 pandemic. (2021-02-04)

BU study: New vaginal film, MB66, is safe
Researchers at Boston University School of Medicine (BUSM), Alpert Medical School of Brown University and Mapp Biopharmaceutical have now found that MB66, a vaginal film product containing monoclonal antibodies against human immunodeficiency virus-type 1 (HIV-1) and herpes simplex viruses types 1 and 2 (HSV-1 and 2), is safe and effective. (2021-02-03)

First-in-human clinical trial confirms HIV vaccine approach by IAVI and Scripps Research
A phase 1 clinical trial testing a novel vaccine approach to prevent HIV has produced promising results, IAVI and Scripps Research announced today. The vaccine showed success in stimulating production of rare immune cells needed to start the process of generating antibodies against the fast-mutating virus; the targeted response was detected in 97 percent of participants who received the vaccine. (2021-02-03)

Bottoms are up at the HIV Research for Prevention Virtual Conference
Researchers seeking to develop on-demand and behaviorally congruent HIV prevention options for anal sex are reporting the results of three early phase clinical trials of rectal microbicides at the HIV Research for Prevention Virtual Conference. The Phase I studies, led by the National Institutes of Health-funded Microbicide Trials Network, found both of two gel-based products well-tolerated, with higher doses of the active drugs likely required to provide protection from HIV and other sexually transmitted infections. (2021-02-02)

90-day vaginal ring shows promise as method for preventing both HIV and pregnancy
A vaginal ring containing the antiretroviral drug dapivirine and the contraceptive hormone levonorgestrel delivered sustained levels of each drug when used continuously for 90 days - levels likely sufficient to serve its dual purpose for protecting against both HIV and unwanted pregnancy, according to results being presented at HIVR4P. The 90-day dual-purpose ring builds on the monthly dapivirine ring, which, if approved, would be the first biomedical HIV prevention method specifically for women. (2021-01-26)

Medicaid expansion helps uncover undiagnosed HIV infections
Expanding eligibility for Medicaid, the federal-state health insurance program for low-income individuals, was associated with a 13.9% increase in HIV diagnoses, says new research co-written by Dolores AlbarracĂ­n, a professor of psychology and of business administration at Illinois, and Bita Fayaz Farkhad, pictured, an economist and a postdoctoral researcher in psychology at Illinois. (2021-01-26)

HIV treatment in Ethiopia is a 'socioeconomic challenge'
For those who are diagnosed and have begun treatment for HIV, it is standard practice to regularly monitor viral load in the blood to assess response to treatment. A study of people living with HIV in Ethiopia shows that poverty and labour mobility are linked to high viral load despite treatment, indicating treatment failure. The researchers behind the study recommend that socioeconomic conditions should be taken into account to a greater extent in low-income countries. (2021-01-25)

Patients of Asian and black backgrounds more likely to die from COVID, large study reveals
Patients of Asian and black backgrounds suffered disproportionate rates of premature death from COVID-19, according to a study of 1,737 patients by Queen Mary University of London and Barts Health NHS Trust. (2021-01-22)

USC study measures brain volume differences in people with HIV
With access to treatment, HIV has become a lifelong chronic condition for the majority of 38 million people living with it. Understanding how it affects the brain over time is increasingly important for improving both treatment and quality of life. A new study of brain scans of 1,203 HIV-infected adults across 5 continents found that with people with lower white blood cell counts also had less brain volume in the hippocampus and thalamus. (2021-01-15)

Algorithms designed to study language predict virus 'escape' mutations for SARS-CoV-2 and others
By bridging the conceptual divide between human language and viral evolution, researchers have developed a powerful new tool for predicting the mutations that allow viruses to 'escape' human immunity or vaccines. (2021-01-14)

Model analyzes how viruses escape the immune system
MIT researchers have devised a way to computationally model viral escape, using models that were originally developed to model language. The model can predict which sections of viral surface proteins, including those of influenza, HIV, and SARS-CoV-2, are more likely to mutate in a way that allows the virus to evade the human immune system. It can also identify sections that are less likely to mutate, making them good targets for new vaccines. (2021-01-14)

Can menopause be blamed for increased forgetfulness and lack of attention?
If you're a bit more forgetful or having more difficulty processing complex concepts than in the past, the problem may be your menopause stage. A new study claims that menopause stage is a key determinant of cognition and, contrary to previous studies, shows that certain cognitive declines may continue into the postmenopause period. Study results are published online today in Menopause, the journal of The North American Menopause Society (NAMS). (2021-01-13)

Stats on HIV among men who have sex with men could help resolve China's epidemic
China has been dealing with an HIV epidemic and seeing rising infections among male college students who practice sex with men. But what is driving this increase and how to put a halt to it? To find out, scientists from China have conducted a study across seven cities, focusing on recent HIV incidence and resistance to therapy among this population. (2021-01-13)

Formula predicts ideal dose of stem cells to cure HIV
Scientists have determined the optimal conditions following a stem cell transplant that could control HIV without the need of an everyday pill, according to a study published today in eLife. (2021-01-12)

Study finds new evidence of health threat from chemicals in marijuana and tobacco smoke
Scientists at Dana-Farber Cancer Institute and the Centers for Disease Control and Prevention have uncovered new evidence of the potential health risks of chemicals in tobacco and marijuana smoke. (2021-01-11)

Oncotarget: HIV +/- patients with lymphoma as a predictor of outcome & tumor proliferation
The Oncotarget author's hypothesis is that ADC values will inversely correlate with Ki-67 expression and that tumors with higher ADC values above the median will have improved OS and PFS (2021-01-11)

Study examines attitudes toward long-acting injectable HIV therapy among women
A study led by Columbia University Mailman School of Public Health researchers examines attitudes toward long-acting injectable (LAI) HIV therapies, among women with a history of injection--including medical purposes and substance use. The findings appear in the journal AIDS Patient Care and STDs. (2021-01-07)

UC researcher urges caution using remdesivir to treat COVID-19
Research at the University of Cincinnati, however, contends that this antiviral drug is being used too indiscriminately when treating patients hospitalized with the virus. The study is published in the journal Fundamental & Clinical Pharmacology. (2020-12-29)

Gates Foundation helps UC study sexual health of South African youth
An important new finding by University of Cincinnati researchers could help slow the transmission of HIV/AIDS and reduce pregnancies among adolescent girls in rural South Africa. (2020-12-22)

Sixfold increase in risk
A research team at the Technical University of Munich (TUM) has quantified the effects of an infection with the Human Immunodeficiency Virus (HIV) on the development of cervical cancer. Their results show that the risk of developing cervical cancer is six times higher in women who are infected with HIV. Southern and Eastern Africa are particularly affected. (2020-12-21)

Researchers propose process to detect and contain emerging diseases
University of Arkansas biologist Kristian Forbes is part of a global team of researchers developing a strategy to detect and intercept diseases emerging from wildlife in Africa that could eventually infect humans. (2020-12-18)

Impaired blood vessel and kidney function underlie heart disease risk in people with HIV
People living with human immunodeficiency virus (HIV) have impaired blood vessel function, which increases risk of heart and blood vessel-disease. The increased heart disease risk is especially pronounced in people with HIV who also have kidney disease. The increased heart disease risk remains regardless of HIV severity or use of antiretroviral therapy. (2020-12-17)

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