Current Head Injury News and Events

Current Head Injury News and Events, Head Injury News Articles.
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Research finds blood pressure can be controlled without drugs after spinal cord injury
Canadian and Swiss researchers have created the first platform to understand the mechanisms underlying blood pressure instability after spinal cord injury. The discovery has led to a new cutting-edge solution. Spinal cord stimulators can bridge the body's autonomous regulation system, controlling blood pressure without medication. Findings are published in Nature. (2021-01-27)

Mouse study: gabapentin prevents harmful structural changes in spinal cord
Research led by The Ohio State University Wexner Medical Center and College of Medicine found that the widely prescribed pain-relief drug gabapentin can prevent harmful structural changes in the injured spinal cords of mice, and also block cardiovascular changes and immune suppression caused by spinal cord injury. (2021-01-26)

ACSL1 as a main catalyst of CoA conjugation of propionic acid-class NSAIDs in liver
Researchers from Kanazawa University have found that propionic acid-class nonsteroidal anti-inflammatory drugs (NSAIDs), including ibuprofen, form ''conjugates'' with coenzyme A (CoA) by one of the acyl-CoA synthetases, ACSL1, in liver. These conjugates have the covalent binding ability to cellular proteins that may lead to liver injury, a rare severe side effect of NSAID treatment. This knowledge could help pharmaceutical companies to generate pain control options with fewer risks of severe side effects. (2021-01-22)

Lack of sleep, stress can lead to symptoms resembling concussion
A new study suggests that a lot of people might be going through life with symptoms that resemble concussion - a finding supporting researchers' argument that athletes recovering from a brain injury should be assessed and treated on a highly individualized basis. (2021-01-22)

University of Cincinnati research unveils possible new combo therapy for head and neck cancer
Researchers at the University of Cincinnati have tested a new combination therapy in animal models to see if they could find a way to make an already effective treatment even better. Since they're using a Food and Drug Administration-approved drug to do it, this could help people sooner than later. (2021-01-22)

Risk factors for intraoperative pressure injury in aortic surgery
In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.1263, Yao Dong, Jun-E Liu and Ling Song from the Capital Medical University, Beijing, China consider risk factors for intraoperative pressure injury in aortic surgery. (2021-01-22)

Predictive value of blood pressure, heart rate, and blood pressure/heart rate ratio in a Chinese subpopulation with vasovagal syncope
In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.1266, Zhuzhi Wen, Jingying Hou, Zun Mai, Huifen Huang, Yangxin Chen, Dengfeng Geng and Jingfeng Wang from Sun Yat-sen University, Guangzhou, China and Guandong Province Key Laboratory of Arrhythmia and Electrophysiology, Guangzhou, China consider predictive value of blood pressure, heart rate, and blood pressure/heart rate ratio in a Chinese subpopulation with vasovagal syncope. (2021-01-22)

Study reveals new insights into the link between sunlight exposure and kidney damage
A new collaborative study from researchers at the Geisel School of Medicine at Dartmouth and the University of Washington and published in the Proceedings of the National Academy of Sciences (PNAS), reveals unexpected insights into how skin exposure to ultraviolet light can worsen clinical symptoms in autoimmune diseases such as lupus. (2021-01-21)

New research finds connection: Inflammation, metabolism and scleroderma scarring
Study finds NAD+ break down leads to multi organ scarring, providing now a previously undiscovered pathogenic role of the enzyme CD38 in disease scarring. (2021-01-19)

Timing is of the essence when treating brain swelling in mice
Researchers from the National Institutes of Health have discovered Jekyll and Hyde immune cells in the brain that ultimately help with brain repair but early after injury can lead to fatal swelling, suggesting that timing may be critical when administering treatment. These dual-purpose cells, which are called myelomonocytic cells and which are carried to the brain by the blood, are just one type of brain immune cell that NIH researchers tracked, watching in real-time as the brain repaired itself after injury. (2021-01-18)

Designer cytokine makes paralyzed mice walk again
To date, paralysis resulting from spinal cord damage has been irreparable. With a new therapeutic approach, scientists from the Department for Cell Physiology at Ruhr-Universit├Ąt Bochum (RUB) headed by Professor Dietmar Fischer have succeeded for the first time in getting paralyzed mice to walk again. The keys to this are the protein hyper-interleukin-6, which stimulates nerve cells to regenerate, and the way how it is supplied to the animals. (2021-01-15)

Effects of head trauma from intimate partner violence largely unrecognized
Carrie Esopenko, assistant professor at the Rutgers School of Health Professions, speaks on new international effort to understand ramifications of concussions and head and neck injuries sustained due to intimate partner violence. (2021-01-14)

MicroRNA may serve as therapeutic targets for traumatic brain injury
WRAIR scientists have shown that traumatic brain injury causes coordinated microRNA dysregulation followed by increased amounts of the beta-site amyloid cleaving enzyme, or BACE1, and loss of amyloid precursor protein. BACE-1 cleaves APP to generate amyloid beta peptides, a hallmark of neurodegenerative disease pathology and brain cells loss, which are the focus of several clinical trials for Alzheimer's disease. Future research will characterize the direct role of miRNAs and their relationship to BACE1 within TBI. (2021-01-14)

Age matters in identifying maltreatment in infants and young children with fractures
Among children who were not in an independently verified incident, evaluation for child abuse should be done by specialty consultation in children aged less than three-years old presenting with rib fractures and children aged less than 18-months presenting with humeral or femoral fractures. (2021-01-13)

New treatment allows some people with spinal cord injury to regain hand and arm function
University of Washington researchers helped six Seattle-area people with spinal cord injuries regain some hand and arm mobility. (2021-01-12)

New hard disk write head analytical technology can increase hard disk capacities
Using synchrotron radiation at SPring-8 - a large-scale synchrotron radiation facility - Tohoku University, Toshiba Corporation, and the Japan Synchrotron Radiation Research Institute (JASRI) have successfully imaged the magnetization dynamics of a hard disk drive (HDD) write head for the first time, with a precision of one ten-billionth of a second. The method makes possible precise analysis of write head operations, accelerating the development of the next-generation write heads and further increasing HDD capacity. (2021-01-07)

Identifying strategies to advance research on traumatic brain injury's effect on women
Analysis from a workshop convened by the National Institute of Neurological Disorders and Stroke (NINDS) in 2017 reveals gaps in and opportunities for research to improve understanding of the effects of traumatic brain injury (TBI) in women. A new paper in the Journal of Head Trauma Rehabilitation summarizes and updates the findings presented during the 'Understanding Traumatic Brain Injury in Women' workshop and provides strategies for advancing research efforts in this area. NINDS is part of the National Institutes of Health. (2021-01-06)

Mouse study finds link between gut disease and brain injury in premature infants
Working with mice, researchers at Johns Hopkins Medicine and the University of Lausanne in Switzerland have identified an immune system cell that they say travels from the gut to the brain and attacks cells rather than protect them as it normally does. (2021-01-06)

Bedside EEG test can aid prognosis in unresponsive brain injury patients
Assessing the ability of unresponsive patients with severe brain injury to understand what is being said to them could yield important insights into how they might recover, according to new research. (2021-01-05)

Brain cancer linked to tissue healing
Brain tumours might arise from an injury that could not heal properly, Canadian scientists have found. The researches detected an increase in inflammation markers typical of injury response in the cells that give rise to glioblastoma, the most common and aggressive form of brain cancer, indicating the cancer cells' potential role in tissue healing. The unexpected findings open new ideas about how brain tumours develop while suggesting that anti-inflammatory medications might benefit some glioblastoma patients. (2021-01-04)

Nanoparticle drug-delivery system developed to treat brain disorders
To facilitate successful delivery of therapeutic agents to the brain, a team of bioengineers, physicians, and collaborators at Brigham and Women's Hospital and Boston Children's Hospital created a nanoparticle platform, which can facilitate therapeutically effective delivery of encapsulated agents in mice with a physically breached or intact BBB. In a mouse model of traumatic brain injury (TBI), they observed that the delivery system showed three times more accumulation in brain than conventional methods of delivery. (2021-01-01)

Study: in social media safety messages, the pictures should match the words
When using social media to nudge people toward safe and healthy behaviors, it's critical to make sure the words match the pictures, according to a new study. After looking at social media posts, parents of young children were better able to recall safety messages such as how to put a baby safely to sleep when the images in the posts aligned with the messages in the text. (2020-12-31)

College football players underestimate risk of injury and concussion
College football players may underestimate their risk of injury and concussion, according to a new study published today in JAMA Network Open. Christine Baugh, PhD, MPH, assistant professor of medicine at the University of Colorado School of Medicine and member of the CU Center for Bioethics and Humanities, is the corresponding author of the article, ''Accuracy of US College Football Players' Estimates of Their Risk of Concussion or Injury.'' (2020-12-29)

Female athletes in WNBA don't return to elite performance for at least 2 years after ACL surgery
Study findings of ACL injuries in WNBA athletes sets return to sport expectations for all female athletes (2020-12-21)

New study: available drugs can prevent rejection and tissue injury after transplantation
Controlling inflammation after transplantation of organs, cells, or tissues is critical for graft survival; however, it can be difficult. Continuing injuries due to chronic rejection can be particularly problematic. Now, a team of researchers from Albert Einstein College of Medicine report that neutralizing the cell signaling molecule, tumor necrosis factor (TNF), can prevent cascades of injurious molecules and signals after cell transplantation in The American Journal of Pathology, published by Elsevier. (2020-12-21)

Despite decrease in recent years, rate of sledding-related injuries still concerning
A new study conducted by researchers at the Center for Injury Research and Policy at Nationwide Children's Hospital found that 220,488 patients were treated in U.S. emergency departments for injuries related to sledding from 2008 through 2017. Nearly 70% of these patients were children age 19 years and younger. (2020-12-16)

Neuroregenerative gene therapy
Spinal cord injury (SCI) often causes disability and seriously compromises quality of life. The major reasons for the difficulty of treatment for SCI might be due to the fact that many neurons are lost during the injury, leading to permanent loss of neural functions. An innovative gene therapy approach regenerated functional new neurons using local glial cells in the injured spinal cord, bringing new hope to millions of SCI patients worldwide. (2020-12-16)

Nearly half of young drivers are resuming driving just weeks after sustaining a concussion
Researchers found that nearly half of adolescents who sought specialty care for a concussion were back to driving when asked approximately two weeks after the injury, even though few had returned to exercise and sports. (2020-12-15)

How water helps the substrate into the enzyme
Researchers from Bochum and Berkeley have investigated why cages can increase the catalytic activity of enclosed molecules. Using terahertz spectroscopy and complex computer simulations, they showed that water encapsulated in a tiny cage has special properties - that are structurally and dynamically distinct from any known phase of water. The water forms a droplet inside the cage that facilitates the encapsulation of a host molecule, i.e. to access the catalytic centre. (2020-12-15)

Genes play a role in common knee injury
It has long been known that the choice of shoe, surface and type of sport can all be contributing factors when someone suffers an anterior cruciate ligament rupture. Researchers at Lund University in Sweden have now observed that genes also play a decisive role. (2020-12-15)

Robotic exoskeleton training improves walking in adolescents with acquired brain injury
'At the end of the 4-week training, participants had progressed to a more normal gait pattern,' said Dr. Karunakaran, 'including improved loading, a longer step length and faster walking speed' Although results are promising, Dr. Nolan acknowledged the limitations of the study, including small sample size and lack of a control group: 'Further study is needed to confirm the training effect in this age group with ABI, optimal dosing for the training protocol, and the durability of functional improvements.' (2020-12-14)

FEFU scientists suggest using neuromodulation to treat patients with spinal cord injuries
Scientists from Far Eastern Federal University (FEFU) together with leading international experts suggest reconsidering the existing treatment protocol for severe spasticity, one of the main complications after spinal cord injury with partial spinal cord disruption. Spasticity aggravates a patient's state and dramatically reduces the prospects of rehabilitation. The new treatment protocol has been run at FEFU Medical Center. A related article was published in the Progress in Brain Research journal. (2020-12-10)

Police investigators of online child abuse at risk of mental harm
Researchers at the University of Portsmouth and Solent University explored moral injury amongst child exploitation investigators and interviewed police officers from two Constabularies during a year-long study. The CREST (Centre for Research and Evidence on Security Threats) funded project asked questions relating to motivations for beginning the role, any personality changes, prior trauma, difficulties relating to their current role, coping mechanisms, moral decision making and use of professional support. (2020-12-10)

Natural antibiotics produced in wounds increase sleep and survival after injury
When wounded, our body sets off a complex immune response. As part of it, the wound produces small antimicrobial molecules to fight off the pathogens locally. Researchers from the Biotechnology Center (BIOTEC) of the TU Dresden and Max Planck Institute for Biophysical Chemistry in collaboration with the Centre d'Immunologie de Marseille-Luminy (CIML) in France have found that these natural antibiotics can also act as long-range molecular messengers. (2020-12-09)

Way to support effective brain performance after head injury backgrounded by lack of sleep
Scientists from the School of Biomedicine of Far Eastern Federal University (FEFU) with colleagues from Italy, Spain, Romania, and Sweden suggest a way to protect the brain and minimize neurodegenerative processes after concussion head injuries in the presence of extensive previous sleep deprivation. This methodology is especially important given the retirement-age increase that has recently become an international trend. A related article appears in the Progress in Brain Research journal. (2020-12-08)

Damage to brain cells reverberates to 'bystander' cells, study finds
Injury or disease that afflicts a relatively small number of brain cells causes a chain reaction that stops activity across a vast network of neural circuits, according to new research. The study may help to explain why people can suffer from temporary but severe loss of cognitive function in cases of traumatic brain injury or disease. (2020-12-08)

Increase in head start funding 'a national priority'
Increased funding for Head Start -- the largest federally funded, early childhood development program in the United States -- is needed to support families during the COVID-19 recession and to ensure a more stable economic recovery. (2020-12-07)

329 people injured by firearms in US each day, but for every death, 2 survive
Researchers examine trends in fatal and nonfatal firearm injuries to inform prevention strategies, finding that twice as many people who are shot survive than die. (2020-12-07)

Kidney injury in diabetic ketoacidosis linked to brain injury
Researchers have identified factors that make children with diabetic ketoacidosis more likely to experience acute kidney injury. Analyzing data from a large, multicenter clinical trial, the researchers also found that children who experience acute kidney injury are more likely to also experience subtle cognitive impairment and demonstrate lower IQ scores, suggesting a pattern of multiple organ injury. (2020-12-04)

Adaptive Image Receive (AIR) coil from GE shows promise for whole-brain imaging
According to an article in ARRS' American Journal of Roentgenology (AJR), a prototype 16-channel head Adaptive Image Receive (AIR) radiofrequency coil from GE Healthcare outperformed a conventional 8-channel head coil for in vivo whole-brain imaging, though it did not perform as well as a conventional 32-channel head coil. (2020-12-03)

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