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Current Heart Failure News and Events, Heart Failure News Articles.
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Fracking sites may increase heart failure hospitalizations across large regions
Heart failure patients who live in communities affected by fracking are at increased risk for hospitalization, according to a study published in the Journal of the American College of Cardiology today. The study looked at the environmental exposure risk of thousands of heart failure patients across Pennsylvania. (2020-12-07)

Scientists discover how COVID-19 virus causes multiple organ failure in mice
UCLA researchers are the first to create a version of COVID-19 in mice that shows how the disease damages organs other than the lungs. Using their model, the scientists discovered that the SARS-CoV-2 virus can shut down energy production in cells of the heart, kidneys, spleen and other organs. (2020-12-07)

Researchers uncover significant reason older adults are at greater risk of heart attack
A team of surgeons has found an insufficient level of the protein Sesn2 is the reason older individuals are at greater risk of heart attack, which indicates stabilizing the protein could be the answer to maintaining a healthy heart. (2020-12-03)

Patients with heart rhythm disorder warned against heavy alcohol consumption
Fourteen drinks a week is linked with a higher risk of health problems including stroke and embolism in patients with atrial fibrillation, according to research published in EP Europace, a journal of the European Society of Cardiology (ESC). ''Our study suggests that atrial fibrillation patients should avoid heavy alcohol consumption to prevent stroke and other complications,'' said author Dr. Boyoung Joung of Yonsei University College of Medicine, Seoul, Republic of Korea. (2020-12-02)

Kidney disease leading risk factor for COVID-related hospitalization
An analysis of Geisinger's electronic health records has revealed chronic kidney disease to be the leading risk factor for hospitalization from COVID-19. (2020-12-02)

COVID-19 can impact young children's hearts
A 2-month-old infant diagnosed with COVID-19 experienced reversible myocardial injury and heart failure, similar to COVID-19 related heart issues seen in adults, according to a case published in JACC: Case Reports. The infant recovered with normal heart function and was discharged with no heart failure medications. (2020-12-02)

Lab results don't explain 'obesity paradox,' but bias may
Results of standard laboratory tests performed on adult outpatients to provide an overall picture of their health are fairly consistent between those with obesity and their leaner counterparts, investigators report. (2020-12-01)

How thyroid function affects stress-related heart problems
Chest pain, shortness of breath, heart flutter and palpitations: these symptoms are not only characteristic of a heart attack, but can also be caused by another, as yet little researched condition. So-called Takotsubo cardiomyopathy is a rare but life-threatening disease of the heart that can occur during extreme stress events. Heart and hormone research teams in Bochum and Mannheim have now shown that there is apparently a strong link between the occurrence of Takotsubo syndrome and impaired thyroid function in patients. (2020-12-01)

Women found to be at higher risk for heart failure and heart attack death than men
Researchers found women face a 20% increased risk of developing heart failure or dying within five years after their first severe heart attack compared with men. In addition, women were more likely than men to be older and have a more complicated medical history at the time of their heart attacks. (2020-11-30)

How dolphins avoid "the bends"
New evidence indicates that dolphins are able to consciously slow down their heart rates when preparing to dive, and can even adjust their heart rates according to the length of their intended dive. This allows them to conserve oxygen and adjust their body to the changing pressure as they dive, therefore avoiding issues such as ''the bends''. (2020-11-24)

Less sedentary time reduces heart failure risk for older women
The more waking hours older women spend sitting or lying down, the more likely they are to require hospitalization for heart failure. The association between sedentary hours and heart failure was present in postmenopausal women with a variety of health conditions and strikingly, even among women who were active at guideline-recommended levels. (2020-11-24)

Scoring system improves screening for "dual" heart disease
Aortic stenosis is one of the most common heart valve defects. As well as conventional valve replacement involving open-heart surgery, a less invasive procedure has now been available for some time in the form of transcatheter aortic valve replacement (TAVR). (2020-11-24)

Treatment shows reduction in heart failure after myocardial infarction
Researchers at Baylor College of Medicine identified potential preventative therapies for heart failure after a significant heart attack. (2020-11-24)

Hypertrophic cardiomyopathy guideline encourages shared decision-making
The American Heart Association and the American College of Cardiology today released an updated guideline for managing patients with hypertrophic cardiomyopathy (HCM). The guideline encourages shared decision-making between the clinician and patient as essential when determining treatment course and updates recommendations for sudden cardiac death (SCD) risk assessment and HCM center referrals based on the latest evidence. (2020-11-20)

A bypass route for the coronary vessels in the heart?
When the heart develops, some of its coronary blood vessels develop from cells lining the inner surface of the heart's ventricular chambers (endocardium). Novel findings suggest that new blood vessel growth in the heart can be stimulated with the VEGF-B growth factor from the same source after myocardial infarction to increase blood delivery to the damaged area. (2020-11-19)

A novel drug target for neonatal and infant heart failure
Researchers have identified a new druggable target for heart failure in neonates and infants. Approximately 60 percent of children born with congenital heart abnormalities will develop overt heart failure within the first year of life. The progression of heart failure in these infants is often rapid, with a high frequency of fatalities. Stimulation of this target significantly increased the cardiac contractility of newborns and infants in mice with few side effects. (2020-11-19)

A case of pediatric heart failure caused by anomalous origin of the left coronary artery from the pulmonary artery
In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0585, Lei Zhang, Tiewei Lv, Xiaoyan Liu, Chuan Feng, Min Zheng, Jie Tian and Huichao Sun from the Children's Hospital of Chongqing Medical University, Chongqing, China and the Chongqing Key Laboratory of Pediatrics, Chongqing, China consider a case of pediatric heart failure caused by anomalous origin of the left coronary artery from the pulmonary artery. (2020-11-19)

JACC: BTS study looks at COVID-19's impact on cardiovascular tissue, endothelial cells
In the paper, ''Cardiorenal tissues express SARS-CoV-2 entry genes and basigin (BSG/CD147) increases with age in endothelial cells,'' publishing in JACC: Basic to Translational Research, researchers used publicly available gene expression data to determine the relative expression of key SARS-CoV-2 host entry/ processing genes in human cardiorenal tissues, including aorta, coronary artery, heart (atria and left ventricle), whole blood and the kidney and for comparison the colon, spleen and lung. (2020-11-18)

Cellular pathway of genetic heart disease similar to neurodegenerative disease
Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy. (2020-11-18)

New diabetes medication reduced heart event risk in those with diabetes and kidney disease
Sotagliflozin - a type of medication known as an SGLT2 inhibitor primarily prescribed for Type 2 diabetes - reduces the risk of adverse cardiovascular events for patients with diabetes and kidney disease. Researchers say the results of this randomized clinical trial provide evidence that SGLT2 inhibitors should be part of the standard of care for people with Type 2 diabetes and chronic kidney disease. (2020-11-17)

New medication helps heart health in people with chronic kidney disease, Type 2 diabetes
Results of a large, international clinical trial on the novel medication finerenone indicate it reduced the rate of death, heart attack, stroke and hospitalization for heart failure among patients with chronic kidney disease and Type 2 diabetes. Finerenone helped patients with chronic conditions improve their heart health, regardless of if they had a history of cardiovascular disease. (2020-11-17)

COVID-19 patient outcomes affected by cardiovascular risk
DALLAS - Nov. 17, 2020 - Research presented today by UT Southwestern cardiologists at the annual American Heart Association (AHA) Scientific Sessions 2020 showed that Black and Hispanic people were more likely to be hospitalized with COVID-19 than white patients, and that nonwhite men with cardiovascular disease or risk factors were more likely to die. (2020-11-17)

High-dose equal to standard flu vaccine for risk of death or heart, lung hospitalization
A high-dose, trivalent influenza vaccine was no more effective than the standard-dose quadrivalent vaccine at reducing the risk of death or hospitalization for heart or lung-related causes among patients with heart disease. While overall there were few serious side effects in both vaccine groups, those who received the high-dose vaccine had more injection-related side effects such as pain, swelling and muscle aches. (2020-11-17)

Patient engagement program for heart failure patients improved outcomes
Nearly half of patients who received support through a patient engagement tool prior to a cardiology clinic visit had a positive change in their medication therapy compared to less than a third among patients who did not receive the engagement tool. The most common medication change was to increase the dose of generic medications already prescribed. (2020-11-17)

Pre-recorded audio messages help improve outcomes for patients with heart failure
Heart failure patients who listened to pre-recorded audio messages of support and guidance were 27% less likely to return to the emergency department one-month after discharge. At 90-days after hospital discharge, the odds of all-cause death and heart failure death decreased by 43% and 48%, respectively, among those who received the audio card. Consistent messages over time may lead to better behaviors in diet, activity and medication therapy for patients discharged from the hospital with heart failure. (2020-11-17)

Just hours of training triples doctor confidence in use of handheld ultrasound devices
Filling a training gap, a Penn Medicine doctor created a geriatric medicine-centered course for point-of-care-ultrasound (POCUS) devices that doubled doctor confidence. (2020-11-17)

Healthy sleep habits help lower risk of heart failure
Healthy sleep habits are associated with a lower risk of heart failure. Adults with the healthiest sleep patterns (morning risers, sleeping 7-8 hours a day and no frequent insomnia, snoring or excessive daytime sleepiness) experienced a 42% reduction in the risk of heart failure compared to those with unhealthy sleep patterns. (2020-11-16)

Bursts of exercise can lead to significant improvements in indicators of metabolic health
Short bursts of physical exercise induce changes in the body's levels of metabolites that correlate to, and may help gauge, an individual's cardiometabolic, cardiovascular and long-term health, a study by Massachusetts General Hospital has found. Approximately 12 minutes of acute cardiopulmonary exercise impacted more than 80% of circulating metabolites, including pathways linked to a range of favorable health outcomes, thus identifying potential mechanisms that could contribute to a better understanding of cardiometabolic benefits of exercise. (2020-11-16)

Preventing heart disease should be a priority for people with Type 2 diabetes
Even when risk factors associated with cardiovascular disease are optimally controlled, adults with Type 2 diabetes still have a greater risk of developing cardiovascular disease compared to the general population, according to new research published today in the American Heart Association's flagship journal Circulation. (2020-11-16)

A change of heart -- new drug for HCM reduces heart mass
For the first time, a medication has impacted heart muscle thickness and function for patients with the most common inherited heart condition, hypertrophic cardiomyopathy, rather than simply addressing their symptoms. (2020-11-16)

SCORED and SOLOIST trials add to evidence for treating diabetes with SGLT2 inhibitors
In these two paired trials, teams of investigators led by Brigham cardiologist Deepak L. Bhatt, MD, MPH, evaluated sotagliflozin, a drug that inhibits SGLT2 and SGLT1. Results of the trials are both published in The New England Journal of Medicine and presented by Bhatt simultaneously at the Late-Breaking Clinical Trial Sessions of the American Heart Association Scientific Sessions. (2020-11-16)

Patients taking statins experience similar side effects from dummy pills
People taking dummy pills and statins experienced similar side effects in a new study. (2020-11-15)

STRENGTH trial finds new fish oil medication did not reduce the risk of cardiac events
A medication derived from fish oil, containing the omega-3 fatty acids EPA and DHA, was evaluated in a large, international study of more than 13,000 people who had existing heart disease or who were at high risk of heart disease due to other medical conditions. The medication did not reduce the risk of cardiac events compared to a corn oil-based placebo in the STRENGTH trial. (2020-11-15)

Omega-3s did not reduce cardiac events in recent heart attack survivors
Omega-3 supplements in commonly available forms appear to be ineffective in preventing further cardiovascular events among elderly people with recent heart attacks. When compared to a placebo, an omega-3 fatty acids supplement in addition to statin therapy and/or a blood thinner did not reduce the number of cardiac events in a study of more than 1,000 patients in Norway. (2020-11-15)

Ticagrelor was not superior to clopidogrel to reduce heart attack risk during angioplasty
A new study found the rate of heart attack and severe complications before, during or soon after elective surgery to open a blocked artery was similar between patients treated with clopidogrel and those who received the more potent antiplatelet medication ticagrelor. (2020-11-14)

Rivaroxaban may be as effective as warfarin for bioprosthetic mitral valves, AF
The RIVER trial is the largest study assessing the efficacy and safety of the anticoagulant rivaroxaban in patients with an artificial mitral valve to correct an irregular heart rhythm. Researchers concluded that rivaroxaban worked as well as the standard anticoagulant medication warfarin. (2020-11-14)

American Heart Association Scientific Sessions to feature Brigham breakthroughs
Leading cardiologists worldwide will convene virtually from November 13-17 at the American Heart Association's 2020 Scientific Sessions, sharing the latest advancements in cardiovascular science and clinical care. The three studies highlighted below represent only a sample of the cutting-edge research Brigham experts in the field will present at the conference. (2020-11-13)

New medicine reduced risk for heart failure emergencies, hospital visits
Results from a large, Phase 3, global, cardiovascular outcomes study indicate a new medication may reduce the risk for heart failure-related events or cardiovascular deaths in people with chronic heart failure. (2020-11-13)

New study confirms combo pill alone and with aspirin lowers heart disease risk
A ''polypill'' is a single pill that includes multiple medications to control more than one health risk factor (such as heart disease, high blood pressure, high cholesterol, Type 2 diabetes, kidney disease, stroke). In this large, international trial, the polypill included blood pressure and cholesterol lowering medications for people at risk for heart disease. Results from the randomized, placebo-controlled trial show that the combination of a polypill plus aspirin reduced cardiovascular disease by 31%, and the polypill without aspirin reduced CVD by 21%. (2020-11-13)

Intravenous iron reduced rehospitalization risk in people with heart failure
Iron deficiency is present in about 50% of people with chronic heart failure. Patients with heart failure who also have iron-deficiency are more likely to have poor outcomes. Intravenous iron replacement with ferric carboxymaltose reduced the risk of heart failure hospitalizations in patients with iron deficiency after an episode of acute heart failure. (2020-11-13)

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