Current Heart Function News and Events

Current Heart Function News and Events, Heart Function News Articles.
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Fat cells may influence how the body reacts to heart failure, study shows
University of Alberta researchers have found that limiting the amount of fat the body releases into the bloodstream from fat cells when in heart failure could help improve outcomes for patients. (2021-02-23)

Give the heart a ketone? It may be beneficial
There is growing evidence that ketone bodies may be beneficial to heart disease patients regardless of the method of delivery used to increase ketone delivery to the heart. A Journal of the American College of Cardiology review paper examines emerging evidence regarding ketone bodies' effects on the heart and the potential for ketone therapy as a cardiovascular intervention in heart disease patients. (2021-02-23)

Structured exercise program, not testosterone therapy improved men's artery health
A 12-week, structured exercise program improved artery health and function in men ages 50 to 70 years old who had low to normal testosterone levels before the program began. Adding testosterone therapy to exercise or testosterone therapy alone did not improve artery health or function. (2021-02-22)

New research on mitochondrial function can play significant part in serious disease
Disorders of the cells' energy supply can cause a number of serious diseases, but also seem to be connected to ageing. More research is needed on mitochondrial function to find future treatments. A new study involving researchers at Karolinska Institutet shows how an important molecule inside the mitochondria affects their function in mice and fruit flies. The study, which is published in Science Advances, adds valuable knowledge on formerly relatively unexplored protein modifications. (2021-02-19)

Real world data on hospital readmissions of patients with heart failure
In an analysis of information on 448 patients with heart failure who were discharged from a hospital in Sweden, 20.3% of patients were readmitted to the hospital within 30 days, and 60.9% were readmitted within 1 year. The ESC Heart Failure analysis found that most of the patients who needed to be rehospitalized were readmitted for heart failure. (2021-02-18)

Stents or bypass surgery more effective for stable patients with high-risk cardiac anatomy
A study by University of Alberta cardiologists at the Canadian VIGOUR Centre shows that a particular group of patients with stable ischemic heart disease have better outcomes with percutaneous coronary intervention (also called angioplasty with stent) or coronary artery bypass surgery and medication, versus conservative management with medication alone. (2021-02-18)

FSU College of Medicine researcher develops new possibilities to prevent sudden cardiac death
Stephen Chelko, an assistant professor of biomedical sciences at the Florida State University College of Medicine, has developed a better understanding of the pathological characteristics behind arrhythmogenic cardiomyopathy, as well as promising avenues for prevention. (2021-02-17)

Drinking, smoking, and drug use linked to premature heart disease in the young
Recreational drinking, smoking, and drug use is linked to premature heart disease in young people, particularly younger women, finds research published online in the journal Heart. (2021-02-15)

Heartbeat secrets unlocked as cardiac rhythm gene role identified
Researchers have used the zebrafish (Danio rerio) to identify the role of a gene involved in cardiac rhythm, which could help explain the fundamentals of what it takes to make a human heartbeat. (2021-02-15)

Study finds alligator hearts keep beating no matter what
A new study reported by Georgia Tech researchers finds that an alligator heart will not fibrillate when exposed to drastic temperature changes, unlike a rabbit (mammal) heart, which is critically vulnerable to heart trauma under those conditions. The research could help better understand how the heart works and what can cause a deadly arrhythmia - which fundamentally happens when the heart doesn't pump blood correctly any longer. (2021-02-15)

Heart disease deaths rising in young women
A nationwide US study has found increasing death rates from heart disease in women under 65. The research is published in European Heart Journal - Quality of Care and Clinical Outcomes, a journal of the European Society of Cardiology (ESC).1 The study found that while death rates from cancer declined every year between 1999 and 2018, after an initial drop, heart disease death rates have been rising since 2010. (2021-02-10)

Long-term stress linked to increased risk of heart attack
Can long-term stress lead to heart attacks? Most people would probably answer in the affirmative, but the scientific evidence of this is scarce. A new study by researchers from Linköping University in Sweden reveals that the levels of the stress hormone cortisol were increased in the months preceding a heart attack. The results, published in Scientific Reports, suggest that long-term stress is a risk factor for heart attacks. (2021-02-10)

Texas A&M researchers discover energy drinks' harmful effects on heart
A team of researchers, led by a Texas A&M University professor, has found that some energy drinks have adverse effects on the muscle cells of the heart. (2021-02-10)

Higher blood pressure over life span increases congestive heart failure risk in Black people
Starting with early childhood, otherwise healthy Black people show signs of slightly diminished heart muscle strength and a slightly higher blood pressure than their white counterparts, factors which may put them on a course for early development of congestive heart failure, Medical College of Georgia researchers report. (2021-02-08)

Drinking green tea, coffee lowers risk of death for stroke and heart attack survivors
Stroke survivors who drank seven or more cups of green tea each day lowered their risks of multiple causes of death by 62%. Drinking one cup of coffee each day lowered the risks of death for heart attack survivors and for those without a history of stroke or heart attack. (2021-02-04)

Uncovering a link between inflammation and heart disease
Patients with cardiac disease often have chronic inflammation that damages their hearts, even with no infection present. A new study published in Circulation reveals a mechanism that is activating T cells, a type of immune cell, and causing inflammation in the heart. (2021-02-04)

Blink! The link between aerobic fitness and cognition
Researchers from the University of Tsukuba have found evidence that spontaneous eye blink activity, which reflects activity in the dopaminergic system, explains the connection between fitness and cognitive function. This is the first study to indicate that dopamine has an essential role in linking aerobic fitness and cognition. These findings open the door to new research regarding the mechanisms by which exercise improves brain function, and may lead to novel fitness strategies for enhancing cognition. (2021-02-03)

Test for early detection of heart problems reduces risk of heart damage from chemotherapy
Results of a multi-centre, international, clinical trial co-led by Peter Munk Cardiac Centre (PMCC) cardiologist Dr. Dinesh Thavendiranathan point to the benefit of using a more sensitive test to detect heart function issues early, so cancer patients don't have to fight heart failure too. (2021-02-02)

Iron release may contribute to cell death in heart failure
A process that releases iron in response to stress may contribute to heart failure, and blocking this process could be a way of protecting the heart, suggests a study in mice published today in eLife. (2021-02-02)

New weapon for inflammation
Flinders University researchers have discovered a new anti-inflammatory role for well-known blood clot protein fibrinogen, which could support targeted new treatments for kidney, heart and other common diseases. The study in Redox Biology describes how fibrinogen can be protective against hypochlorite - a chemical generated by the body during inflammation - and so act as a kind of antioxidant in blood plasma. (2021-01-31)

Researchers map heart recovery after heart attack with great detail
Researchers from the Hubrecht Institute mapped the recovery of the heart after a heart attack with great detail. They found that cardiomyocytes play an important role in the intracellular communication after a heart attack. The researchers documented their findings in a database that is accessible for scientists around the world. This brings the research field a step closer to the development of therapies for improved recovery after heart injury. (2021-01-29)

First hybrid gene therapy shows early promise in treating long QT syndrome
In a new study published in Circulation, Mayo Clinic researchers provide the first preclinical, proof-of-concept study for hybrid gene therapy in long QT syndrome, a potentially lethal heart rhythm condition. (2021-01-28)

Breakthrough design at UBCO vastly improves mechanical heart valve
New research coming out of UBC's Okanagan campus may take the current 'gold standard' for heart valves to a new level of reliability. A team of researchers at UBCO's Heart Valve Performance Lab (HVPL) has developed a way to improve overall blood flow through the valves, so the design of mechanical heart valves will more closely match the real thing. (2021-01-26)

Mouse study identifies novel compound that may help develop diabetes drugs
Research led by The Ohio State University Wexner Medical Center and College of Medicine identified a new compound that might serve as a basis for developing a new class of drugs for diabetes. Study findings are published online in the journal Nature Chemical Biology. (2021-01-26)

Finding a way to stop chemotherapy from damaging the heart
There could be an intervention on the horizon to help prevent heart damage caused by the common chemotherapy drug doxorubicin, new research suggests. (2021-01-25)

Predictive value of blood pressure, heart rate, and blood pressure/heart rate ratio in a Chinese subpopulation with vasovagal syncope
In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.1266, Zhuzhi Wen, Jingying Hou, Zun Mai, Huifen Huang, Yangxin Chen, Dengfeng Geng and Jingfeng Wang from Sun Yat-sen University, Guangzhou, China and Guandong Province Key Laboratory of Arrhythmia and Electrophysiology, Guangzhou, China consider predictive value of blood pressure, heart rate, and blood pressure/heart rate ratio in a Chinese subpopulation with vasovagal syncope. (2021-01-22)

Counting patients social determinants of health may help doctors avert fatal heart attacks
Doctors may be able to predict their patients' risks of fatal coronary heart disease more accurately by taking into account the number of adverse social factors affecting them, according to a new study led by researchers at Weill Cornell Medicine and NewYork-Presbyterian. (2021-01-21)

Mayo Clinic study indicates age influences sex-related outcomes after heart attack
Approximately 1.5 million heart attacks and strokes occur every year in men and women in the US Sex and age play a large part in who experiences a heart attack, the methods used to treat these heart attacks, and the eventual post hospital outcomes of the people who experience heart attacks. Mayo Clinic researchers discuss these sex and age differences in study findings published in Mayo Clinic Proceedings. (2021-01-20)

Rush researchers demonstrate success with new therapy for COVID-19
A new therapy developed by researchers at Rush University Medical Center is showing success as a way to prevent COVID-19 symptoms in mice. (2021-01-19)

Fried food intake linked to heightened serious heart disease and stroke risk
Fried-food intake is linked to a heightened risk of major heart disease and stroke, finds a pooled analysis of the available research data, published online in the journal Heart. (2021-01-18)

Temple researchers identify cardiac protein that causes different types of heart failure
Heart damage typically progresses, owing to oxidative stress and toxic lipids that alter heart cell energetics and the heart's ability to function normally. Oxidative stress occurs when harmful oxygen-containing molecules outnumber helpful antioxidants, leading to damaging reactions with proteins, DNA, and other cell components. Temple researchers show that in the heart, Kruppel-like factor-5, fuels both the generation of oxidizing molecules and the accumulation of toxic lipids known as ceramides in the heart, exacerbating heart dysfunction. (2021-01-13)

New research reveals early warning sign for heart disease
The build-up of calcium in a major artery outside of the heart could predict future heart attack or stroke, a new Edith Cowan University led study has demonstrated. (2021-01-13)

Hope for children with rare heart condition: novel stem cell therapy to save the day
In a new study, scientists at Okayama University isolated cardiac stem cells and assessed their potential use as regenerative therapy in young patients with cardiac defects. They confirmed the safety and effectiveness of their proposed treatment in early-phase trials and even identified the mechanism through which the stem cells improved cardiac function. Based on these preliminary findings, they hope to proceed to larger clinical trials and move towards pharmaceutical approval in the future. (2021-01-12)

Enhanced oral uptake of exosomes opens cell therapy alternative
Cell-derived exosomes are effective in treating disease when mixed with the dominant protein in breast milk and given orally, a new Smidt Heart Institute study of laboratory mice shows. The findings, published in the peer-reviewed Journal of Extracellular Vesicles, could help develop new oral medications for treating patients with muscular dystrophy and heart failure. (2021-01-12)

Tracking the formation of the early heart, cell by cell
Richard Tyser and colleagues have mapped the origins of the embryonic mouse heart at single-cell resolution, helping to define the cell types that make up the heart in the earliest days of development. (2021-01-07)

COVID-19 infection linked with higher death rate in acute heart failure patients
Patients with acute heart failure nearly double their risk of dying if they get COVID-19, according to research published today in ESC Heart Failure, a journal of the European Society of Cardiology (ESC).1 The small, single centre study highlights the need for patients with heart failure to take extra precautions to avoid catching COVID-19. ''Our results support prioritising heart failure patients for COVID-19 vaccination once it is available,'' said study lead investigator Dr. Amardeep Dastidar. (2021-01-06)

Stopping RAS inhibitors tied to worse outcomes in patients with chronic kidney disease
Small studies have suggested that a group of medications called RAS inhibitors may be harmful in persons with advanced chronic kidney disease, and physicians therefore often stop the treatment in such patients. Researchers at Karolinska Institutet now show that although stopping the treatment is linked to a lower risk of requiring dialysis, it is also linked to a higher risk of cardiovascular events and death. The results are published in The Journal of the American Society of Nephrology. (2020-12-29)

Heart transplantations: prospects of success increase with larger case volumes
Heart transplantations: prospects of success increase with larger case volumes The survival probabilities for patients undergoing surgery are higher in hospitals where heart transplants are performed more frequently. (2020-12-28)

Perspective: Why opioids cannot fix chronic pain
New epidemiological and neuroscientific evidence suggests that the relationship between chronic pain and emotional distress is bidirectional. Pain experts at University of Washington School of Medicine explain the relation in Annals of Family Medicine. (2020-12-22)

Breathing rate predicts therapeutic benefits for heart patients
Conditions causing arrhythmia are among the most common cardiac conditions. A study headed by Prof. Georg Schmidt of the Technical University of Munich (TUM) has demonstrated for the first time that the nocturnal respiratory rate can help with an important prediction: It is an indicator of whether a defibrillator will help to extend the life of patients with arrhythmia. (2020-12-21)

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