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Current Heart Function News and Events, Heart Function News Articles.
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Genetic mutation could worsen heart function in Duchenne muscular dystrophy patients
DALLAS - Nov. 4, 2020 - A mutation in the gene that causes cystic fibrosis may accelerate heart function decline in those with Duchenne muscular dystrophy (DMD), a new study by UT Southwestern researchers suggests. The findings, published online recently in the Journal of the American Heart Association, could help doctors develop new strategies to preserve heart function in this population, potentially extending patients' lives. (2020-11-04)

Implantable device can monitor and treat heart disease
Cunjiang Yu, Bill D. Cook Associate Professor of Mechanical Engineering at UH, led a group of researchers that has reported developing a cardiac patch made from fully rubbery electronics that can be placed directly on the heart to collect electrophysiological activity, temperature, heartbeat and other indicators, all at the same time. (2020-11-03)

UConn researcher identifies genetic elements involved in heart development
Justin Cotney, assistant professor of genetics and genome sciences in the UConn School of Medicine, has identified a suite of genes and regulatory elements critical to normal heart development. (2020-11-03)

A patch that could help heal broken hearts
According to the American Heart Association, heart disease is the leading cause of death worldwide in recent years. During a heart attack, or myocardial infarction (MI), a blocked artery and the resulting oxygen deprivation cause massive cardiac cell death, blood vessel impairment and inflammation. Now, researchers reporting in ACS Biomaterials Science & Engineering have developed a cardiac patch with tiny engineered blood vessels that improved recovery from MI in rats and pigs. (2020-10-28)

A study has demonstrated that omega-3 rich foods improve post-heart attack prognosis
A team of researchers from the Germans Trias i Pujol Hospital and Research Institute (IGTP) and the Hospital del Mar Medical Research Institute (IMIM) has shown that regularly consuming foods rich in omega-3 fatty acids, from both animal and vegetable origins, strengthens the heart's membranes and helps improve the prognosis in the event of a myocardial infarction. To arrive at these conclusions, they used data from 950 patients. (2020-10-27)

Study reinforces drug's potential to treat hypertrophic cardiomyopathy
WSU research sheds new light on a molecule that may be used to treat heart conditions that can lead to stroke, heart attack and other forms of heart disease. (2020-10-27)

Emerging treatment helps reverse heart failure in some patients
In a new multicenter study, researchers report that an emerging heart failure treatment could potentially reverse structural damage to the heart, allowing it to heal itself over time. They say the treatment could eliminate the need for heart transplants and long-term use of artificial heart pumps in certain cases. Overall, 40% who were treated with this protocol that combined LVAD support with standard heart failure medications had sufficient improvement that the LVAD could be removed. (2020-10-26)

A heart-breast cancer-on-a-chip monitoring system
Dual-organ system enables the measurement of cardiac toxicity arising from breast cancer chemotherapy. A collaborative team, which includes a group from the Terasaki Institute for Biomedical Innovation, has developed an organs-on-a-chip system that more widely examines the responses of breast cancer and heart tissues to therapeutic breast cancer drugs. (2020-10-26)

High fat or 'ketogenic' diets could prevent, reverse heart failure
Research from Saint Louis University finds that high fat or ''ketogenic'' diets could completely prevent, or even reverse heart failure caused by a metabolic process. The research team, led by Kyle S. McCommis, Ph.D., assistant professor in Biochemistry and Molecular Biology at SLU, looked at a metabolic process that seems to be turned down in failing human hearts. (2020-10-26)

Aging alone does not explain kidney pathology
Histopathology in non-neoplastic kidney tissue from 1,347 nephrectomy specimens showed very limited histopathologic changes in subset of older individuals. (2020-10-21)

Children with chronic kidney disease have outsized health burden
Chronically ill children with kidney disease may spend more time in the hospital, incur larger health care costs and have a higher risk of death compared to pediatric patients hospitalized for other chronic conditions, a new study suggests. (2020-10-20)

Does the new heart transplant allocation policy encourage gaming by providers?
A new national policy was created to make determining who receives a heart transplant more fair. But new data shows it changed some practice patterns, too. (2020-10-20)

Cutting-edge, whole-heart imaging provides new details on heart defects
A cutting-edge technique that allows scientists to zoom into tiny details in a 3D image of a whole animal heart may lead to new insights on congenital heart disease. (2020-10-20)

Congenital heart defects may not increase the risk of severe COVID-19 symptoms
People with congenital heart disease had a lower-than-expected risk for severe symptoms from COVID-19, a new study has found. (2020-10-16)

Ultrasound technique offers more precise, quantified assessments of lung health
Researchers have developed a technique that uses ultrasound to provide non-invasive assessments of pulmonary fibrosis and pulmonary edema. The technique has been shown to both quantify lung scarring and detect lung fluid in rats. A study on pulmonary edema in humans is under way. (2020-10-15)

What fuels the beating heart? Study reveals nutrients used by normal and failing hearts
A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has produced a detailed picture of fuel and nutrient use by the human heart. The study was the first of its kind, involving the simultaneous sampling of blood from different parts of the circulatory system in dozens of human participants, in order to record the levels of related molecules going into and coming out of the beating heart. (2020-10-15)

Scientists discover a new mechanism for cellular defense against viral and bacterial infections
Researchers of IDIBAPS, the University of Barcelona and CNIC have coordinated a study, published in Science, which describes a new mechanism of innate immunity by which cells fight viruses and bacteria. (2020-10-15)

Research could change how blood pressure is managed in spinal cord injury patients
New research from the International Collaboration on Repair Discoveries (ICORD) challenges the current standard for managing blood pressure in people with spinal cord injury (SCI). (2020-10-15)

Poor diet is top contributor to heart disease deaths globally
More than two-thirds of deaths from heart disease worldwide could be prevented with healthier diets. That's the finding of a study published today in European Heart Journal - Quality of Care and Clinical Outcomes, a journal of the European Society of Cardiology (ESC). The findings come on World Food Day, which highlights the importance of affordable and sustainable healthy diets for all. (2020-10-15)

Reviving cells after a heart attack
Harvard SEAS researchers have unraveled potential mechanisms behind the healing power of extracellular vesicles and demonstrated their capacity to not only revive cells after a heart attack but keep cells functioning while deprived of oxygen during a heart attack. The researchers demonstrated this functionality in human tissue using a heart-on-a-chip with embedded sensors that continuously tracked the contractions of the tissue. (2020-10-14)

Researchers discover a cell type responsible for cardiac repair after infarction
The researcher of the Faculty of Science of the UMA Adrián Ruiz-Villalba, who is also member of the Andalusian Center for Nanomedicine and Biotechnology (BIONAND) and the Biomedical Research Institute of Malaga (IBIMA), is the first author of an international study that has identified the heart cells in charge of repairing the damage caused to this organ after infarction. This study has been recently published in the American Heart Association journal Circulation, first in the world dedicated to cardiovascular research. (2020-10-13)

New approach helps EMTs better assess chest pain en route to hospital
A study conducted at Wake Forest Baptist Health shows that on-scene use of a new protocol and advanced diagnostic equipment can help paramedics better identify patients at high risk for adverse cardiac events. (2020-10-07)

New method for in utero 4D imaging of baby hearts may aid diagnosis of congenital heart disease
Researchers at King's College London have developed a new method for helping detect congenital heart disease of a baby in pregnant mothers using MRI. Existing in-utero approaches are compromised by fetal motion, but the novel method corrects the motion to present 4D visualizations of the heart depicting major vessels and blood flow circulation. With further development, the method could become a new tool for aiding diagnosis of congenital heart disease where conventional methods like ultrasound might fail. (2020-10-05)

Study: Sleep apnea treatment reduces heart problems in patients with prediabetes
A new study found that people with prediabetes and obstructive sleep apnea can reduce their daytime resting heart rate and risk of cardiovascular disease by using a CPAP machine at night. (2020-10-01)

Study: Unnecessary stress testing performed prior to knee and hip replacement surgeries
A new study out of the University of Chicago Medicine shows the overall rate of preoperative stress testing for hip and knee replacements is and has been decreasing consistently since 2006. Still, researchers found, 30,000 out of every 100,000 stress tests performed each year were unnecessary, as the tests didn't decrease the frequency of complications such as heart attacks or stopped hearts. (2020-10-01)

Cardiac arrhythmias linked to gene mutations
Life-threatening cardiac arrhythmias can be linked to the functional and structural consequences of gene mutations. (2020-09-29)

Discovery of cells that heal cardiac damage after infarction
Researchers at Cima and the Clinica Universidad de Navarra (Spain) have led an international study identifying the cardiac cells responsible for repairing the damage to this organ after infarction. These ''restorative'' cells are a subpopulation of cardiac fibroblasts that play a fundamental role in the creation of the collagen scar needed to avoid the rupture of the ventricular wall. The research also reveals the molecular mechanisms involved in the activation of these cells and the regulation of their function. (2020-09-29)

Study: Childhood chemo alters heart's caretaker cells
Why do 20% of children who receive cancer chemotherapy go on to develop heart failure later in life? UT Health San Antonio researchers led by Gregory Aune, MD, PhD, are studying this question and report a clue in a new journal article. (2020-09-29)

Exosome treatment improves recovery from heart attacks in a preclinical study
Research in pigs shows that using the exosomes naturally produced from a mixture of heart muscle cells, endothelial cells and smooth muscle cells -- which were all derived from human induced pluripotent stem cells -- yields regenerative benefits equivalent to the injected human induced pluripotent stem cell-cardiac cells. (2020-09-29)

Heart disease in young people may be linked to diabetes exposure in the womb
Heart disease in young adults and teenagers may be related to exposure to diabetes in the womb, according to new research published in CMAJ (Canadian Medical Association Journal) http://www.cmaj.ca/lookup/doi/10.1503/cmaj.190797. (2020-09-28)

Anxious, moody older adults are vulnerable to worse cognitive function
Some older adults with the neuropathology that causes dementia have more cognitive resilience than others, reports a new study. The reason: their personalities. Individuals with higher neuroticism -- a greater tendency towards anxiety, worry, moodiness and impulsivity -- were more likely to have worse cognitive function. Individuals who were self-disciplined, organized, high achievers and motivated -- known as higher conscientiousness -- had better cognitive function and memory. (2020-09-25)

Mapping the human heart, cell by cell
Scientists have mapped and described the function of cells in six regions of the adult heart, providing a new foundation for studying heart disease. (2020-09-24)

Highly detailed map of the human heart could guide personalized heart treatments
Scientists have created a detailed cellular and molecular map of the healthy human heart to understand how this vital organ functions and to shed light on what goes awry in cardiovascular disease. (2020-09-24)

New 'atlas' of human heart cells first step toward precision treatments for heart disease
Scientists have for the first time documented all of the different cell types and genes expressed in the healthy human heart, in research published in the journal Nature. Cardiologists from the Mazankowski Alberta Heart Institute at the University of Alberta joined teams from Cambridge, Boston and Berlin to use state-of-the-art analytical techniques to sequence the ribonucleic acids (RNA) in nine types of single cells from six regions of the heart. (2020-09-24)

Analysis reveals heart-related side effects of hydroxychloroquine and chloroquine
As the antimalarial drugs hydroxychloroquine and chloroquine have drawn attention as potential therapies for COVID-19 and are being widely used off-label, it's now more important than ever to have a thorough assessment of the safety of these medications. A recent analysis published in the British Journal of Clinical Pharmacology provides new insights. (2020-09-23)

Grappling with questions about how COVID-19 can affect the heart
For an issue once expected to occur mostly in patients with severe COVID-19, heart conditions following SARS-CoV-2 infection are much more prevalent, writes Eric Topol in a Perspective. (2020-09-23)

Exercise before menopause is important to optimise health in later years
The small blood vessels in muscles of women after menopause are less able to grow compared to young women, according to new research published today in the Journal of Physiology. This means exercising before menopause is all the more important for women in order to develop blood vessels in muscles, and thus the ability to develop muscle strength. (2020-09-22)

Yale succeeds with a more inclusive approach to heart transplants
Doctors at Yale New Haven Hospital used a more aggressive selection process to more than quadruple the number of heart transplants performed there while maintaining positive patient outcomes, according to a new study. (2020-09-18)

Reduction in insomnia symptoms associated with non-invasive neurotechnology
For people with chronic insomnia, a good night's sleep is elusive. But what if insomnia symptoms could be alleviated by simply listening to one's own brainwaves? (2020-09-17)

4TEEN4's first-in-class therapeutic antibody Procizumab restores heart function in life-threatening cardiac depression induced by sepsis
4TEEN4 reports on the efficacy of Procizumab in a preclinical model of sepsis (2020-09-16)

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