Current Heart Transplant News and Events

Current Heart Transplant News and Events, Heart Transplant News Articles.
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Scoring system improves screening for "dual" heart disease
Aortic stenosis is one of the most common heart valve defects. As well as conventional valve replacement involving open-heart surgery, a less invasive procedure has now been available for some time in the form of transcatheter aortic valve replacement (TAVR). (2020-11-24)

Treatment shows reduction in heart failure after myocardial infarction
Researchers at Baylor College of Medicine identified potential preventative therapies for heart failure after a significant heart attack. (2020-11-24)

Afro-Caribbean patients with severe kidney disease at greater risk of hospitalisation from COVID-19
Afro-Caribbean people with end stage kidney disease (ESKD) are more likely to be hospitalised with COVID-19 than other ethnicities, a study has found. (2020-11-19)

A bypass route for the coronary vessels in the heart?
When the heart develops, some of its coronary blood vessels develop from cells lining the inner surface of the heart's ventricular chambers (endocardium). Novel findings suggest that new blood vessel growth in the heart can be stimulated with the VEGF-B growth factor from the same source after myocardial infarction to increase blood delivery to the damaged area. (2020-11-19)

Stem cell transplantation: undesirable rejection mechanism identified
In the treatment of leukaemia, stem cell transplantation subsequent to chemotherapy and radiation can often engender severe adverse inflammatory reactions - especially in the skin or in the gut, since these so-called barrier organs are more frequently affected. Up until now, the reason for this was unclear. A team of researchers in Vienna has now identified an immune mechanism that is partially responsible for this. (2020-11-19)

A case of pediatric heart failure caused by anomalous origin of the left coronary artery from the pulmonary artery
In a new publication from Cardiovascular Innovations and Applications; DOI https://doi.org/10.15212/CVIA.2019.0585, Lei Zhang, Tiewei Lv, Xiaoyan Liu, Chuan Feng, Min Zheng, Jie Tian and Huichao Sun from the Children's Hospital of Chongqing Medical University, Chongqing, China and the Chongqing Key Laboratory of Pediatrics, Chongqing, China consider a case of pediatric heart failure caused by anomalous origin of the left coronary artery from the pulmonary artery. (2020-11-19)

Cellular pathway of genetic heart disease similar to neurodegenerative disease
Research on a genetic heart disease has uncovered a new and unexpected mechanism for heart failure. This landmark discovery found a correlation between the clumping of RNA-binding proteins long linked to neurodegenerative disease and the aggregates of protein found in the heart tissue of patients with RBM20 dilated cardiomyopathy. (2020-11-18)

New medication helps heart health in people with chronic kidney disease, Type 2 diabetes
Results of a large, international clinical trial on the novel medication finerenone indicate it reduced the rate of death, heart attack, stroke and hospitalization for heart failure among patients with chronic kidney disease and Type 2 diabetes. Finerenone helped patients with chronic conditions improve their heart health, regardless of if they had a history of cardiovascular disease. (2020-11-17)

Pre-recorded audio messages help improve outcomes for patients with heart failure
Heart failure patients who listened to pre-recorded audio messages of support and guidance were 27% less likely to return to the emergency department one-month after discharge. At 90-days after hospital discharge, the odds of all-cause death and heart failure death decreased by 43% and 48%, respectively, among those who received the audio card. Consistent messages over time may lead to better behaviors in diet, activity and medication therapy for patients discharged from the hospital with heart failure. (2020-11-17)

Healthy sleep habits help lower risk of heart failure
Healthy sleep habits are associated with a lower risk of heart failure. Adults with the healthiest sleep patterns (morning risers, sleeping 7-8 hours a day and no frequent insomnia, snoring or excessive daytime sleepiness) experienced a 42% reduction in the risk of heart failure compared to those with unhealthy sleep patterns. (2020-11-16)

A change of heart -- new drug for HCM reduces heart mass
For the first time, a medication has impacted heart muscle thickness and function for patients with the most common inherited heart condition, hypertrophic cardiomyopathy, rather than simply addressing their symptoms. (2020-11-16)

Cleveland Clinic led trial shows drug effective in 96% of patients with recurrent pericarditis
Cleveland: Cleveland Clinic researchers leading a global clinical trial have found that rilonacept, an FDA approved drug for other inflammatory diseases, resolved acute pericarditis episodes and reduced risk of pericarditis recurrence. The study was published today in the New England Journal of Medicine and presented at the American Heart Association's Scientific Sessions. (2020-11-16)

American Heart Association Scientific Sessions to feature Brigham breakthroughs
Leading cardiologists worldwide will convene virtually from November 13-17 at the American Heart Association's 2020 Scientific Sessions, sharing the latest advancements in cardiovascular science and clinical care. The three studies highlighted below represent only a sample of the cutting-edge research Brigham experts in the field will present at the conference. (2020-11-13)

Intravenous iron reduced rehospitalization risk in people with heart failure
Iron deficiency is present in about 50% of people with chronic heart failure. Patients with heart failure who also have iron-deficiency are more likely to have poor outcomes. Intravenous iron replacement with ferric carboxymaltose reduced the risk of heart failure hospitalizations in patients with iron deficiency after an episode of acute heart failure. (2020-11-13)

Study: Vitamin D, fish oil don't lower atrial fibrillation risk
New research presented today at the American Heart Association Scientific Sessions suggests neither vitamin D nor the omega-3 fatty acids found in fish oil prevent the development of atrial fibrillation, a potentially serious heart rhythm disturbance. (2020-11-13)

Not all patients with certain type of heart attack receive the same care
An analysis of medical records reveals variability in the tests and treatments that patients with type 2 myocardial infarction receive during and after their hospital stay. Clinical trials are needed to provide guidance to physicians on how to best care for these patients. (2020-11-11)

Simultaneous kidney transplant plus weight loss surgery safe for obese patients
A new study shows that robotic-assisted kidney transplant and weight loss surgery can be performed safely. (2020-11-10)

The natural artistry of disease: a wintry landscape in the eye
Researchers from Tokyo Medical and Dental University (TMDU) report a case of frosted branch angiitis in a woman presenting years after being treated for leukemia-lymphoma with allogeneic human stem cell transplant. The relevance of this ocular finding is discussed and its value as an early warning sign of immune activation following therapeutic immunological interventions is highlighted. (2020-11-09)

Implantable device can monitor and treat heart disease
Cunjiang Yu, Bill D. Cook Associate Professor of Mechanical Engineering at UH, led a group of researchers that has reported developing a cardiac patch made from fully rubbery electronics that can be placed directly on the heart to collect electrophysiological activity, temperature, heartbeat and other indicators, all at the same time. (2020-11-03)

UConn researcher identifies genetic elements involved in heart development
Justin Cotney, assistant professor of genetics and genome sciences in the UConn School of Medicine, has identified a suite of genes and regulatory elements critical to normal heart development. (2020-11-03)

Baking soda treatment may help prevent leukemia relapse after stem cell transplants
Scientists have discovered that sodium bicarbonate - also known as baking soda or bicarbonate of soda - can reprogram T cells in leukemia patients to resist the immune-suppressing effects of cancer cells, which can drive leukemia relapse after stem cell transplants. (2020-10-28)

A study has demonstrated that omega-3 rich foods improve post-heart attack prognosis
A team of researchers from the Germans Trias i Pujol Hospital and Research Institute (IGTP) and the Hospital del Mar Medical Research Institute (IMIM) has shown that regularly consuming foods rich in omega-3 fatty acids, from both animal and vegetable origins, strengthens the heart's membranes and helps improve the prognosis in the event of a myocardial infarction. To arrive at these conclusions, they used data from 950 patients. (2020-10-27)

Study reinforces drug's potential to treat hypertrophic cardiomyopathy
WSU research sheds new light on a molecule that may be used to treat heart conditions that can lead to stroke, heart attack and other forms of heart disease. (2020-10-27)

A heart-breast cancer-on-a-chip monitoring system
Dual-organ system enables the measurement of cardiac toxicity arising from breast cancer chemotherapy. A collaborative team, which includes a group from the Terasaki Institute for Biomedical Innovation, has developed an organs-on-a-chip system that more widely examines the responses of breast cancer and heart tissues to therapeutic breast cancer drugs. (2020-10-26)

Poverty linked to higher risk of death in children with cancer undergoing transplant
Despite the increasing use and promise of hematopoietic cell transplantation (HCT) as curative therapy for children with cancer and other life-threatening diseases, new research suggests that children transplanted for cancer are more likely to die from treatment-related complications if they live in poorer neighborhoods. The study, published today in the journal Blood, also found that having Medicaid versus private insurance, another marker of poverty, was associated with a higher chance of dying. (2020-10-26)

Cell-Free DNA provides a dynamic window into health
A new study presented at the ASHG 2020 Virtual Meeting shows how cfDNA testing can be used to provide insight into a patient's health. (2020-10-26)

Study reveals details behind transplant disparities experienced by black patients
In an analysis of information on patients with kidney failure, Black patients are less likely than white patients to be placed on transplant waiting lists. For patients on such lists, Blacks are less likely to receive transplants than whites. Results from the study will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25. (2020-10-25)

The effects of social determinants of health on kidney transplant candidates
Social determinants of health are associated with patient-reported outcomes in adults who are eligible to undergo kidney transplantation evaluations. Results from the study will be presented online during ASN Kidney Week 2020 Reimagined October 19-October 25. (2020-10-25)

Type 1 diabetes: Tannic acid encapsulation protects transplanted islets from rejection
One therapy for Type 1 diabetes is promising -- transplanting pancreatic islets from cadavers -- but a need for immunosuppression and a reactivated autoimmunity lead to low graft viability and function after five years. Now researchers show that a protective coating of alternating layers of two biopolymers delays allograft and autoimmune-mediated rejection in mouse models of T1D. (2020-10-22)

Children with chronic kidney disease have outsized health burden
Chronically ill children with kidney disease may spend more time in the hospital, incur larger health care costs and have a higher risk of death compared to pediatric patients hospitalized for other chronic conditions, a new study suggests. (2020-10-20)

Does the new heart transplant allocation policy encourage gaming by providers?
A new national policy was created to make determining who receives a heart transplant more fair. But new data shows it changed some practice patterns, too. (2020-10-20)

Cutting-edge, whole-heart imaging provides new details on heart defects
A cutting-edge technique that allows scientists to zoom into tiny details in a 3D image of a whole animal heart may lead to new insights on congenital heart disease. (2020-10-20)

Congenital heart defects may not increase the risk of severe COVID-19 symptoms
People with congenital heart disease had a lower-than-expected risk for severe symptoms from COVID-19, a new study has found. (2020-10-16)

Study reveals kidney disease or injury is associated with much higher risk of mortality for COVID-19 patients in ICU
New research published in Anaesthesia (a journal of the Association of Anaesthetists) reveals the much higher risk of mortality faced by COVID-19 patients in intensive care who have chronic kidney disease (CKD) or, those who develop new (acute) kidney injury (AKI) as a result of developing COVID-19. (2020-10-16)

UT Southwestern leads national efforts around childhood blood disorders
When a child has a rare blood disorder, clinicians can struggle to find the best diagnostic and treatment methods. New research led by UT Southwestern shows the effectiveness of a treatment for aplastic anemia and reveals the range of diagnosis and treatment options used by hospitals around the country for a related disease - myelodysplastic syndrome (MDS). (2020-10-15)

What fuels the beating heart? Study reveals nutrients used by normal and failing hearts
A team led by scientists in the Perelman School of Medicine at the University of Pennsylvania has produced a detailed picture of fuel and nutrient use by the human heart. The study was the first of its kind, involving the simultaneous sampling of blood from different parts of the circulatory system in dozens of human participants, in order to record the levels of related molecules going into and coming out of the beating heart. (2020-10-15)

New approach helps EMTs better assess chest pain en route to hospital
A study conducted at Wake Forest Baptist Health shows that on-scene use of a new protocol and advanced diagnostic equipment can help paramedics better identify patients at high risk for adverse cardiac events. (2020-10-07)

Hearts harvested from pigs may soon help solve chronic shortages of these donor organs
An analysis discusses scientific breakthroughs that have overcome obstacles to cardiac xenotransplantation. (2020-10-07)

New method for in utero 4D imaging of baby hearts may aid diagnosis of congenital heart disease
Researchers at King's College London have developed a new method for helping detect congenital heart disease of a baby in pregnant mothers using MRI. Existing in-utero approaches are compromised by fetal motion, but the novel method corrects the motion to present 4D visualizations of the heart depicting major vessels and blood flow circulation. With further development, the method could become a new tool for aiding diagnosis of congenital heart disease where conventional methods like ultrasound might fail. (2020-10-05)

Could a poo transplant one day be the secret of eternal youth?
Poo transplants could one day be used to restore cognitive decline among the elderly - according to new research. A new study published today shows how faecal transplants from older to younger mice altered their gut microbiome, which in turn impacted their spatial learning and memory. The research team hope the reverse could also be true, and one day used as a therapy to restore cognitive function in older people. (2020-10-02)

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