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Current Heart Transplant News and Events, Heart Transplant News Articles.
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Are organ transplant recipients at greater risk of death from COVID-19?
A new study analyzes death risk from COVID-19 in organ transplant recipients and finds one treatment method greatly increased the risk. (2020-10-01)

UM171 saves another life
Developed in Canada, the UM171 molecule was used in a blood transplant by a Montreal medical team on a young man suffering from severe aplastic anemia, an autoimmune disease. (2020-09-30)

Pioneering dual surgery a safe option for patients with polycystic kidney disease
Patients with large polycystic kidneys in need of a kidney transplant can have their diseased kidneys safely removed laparoscopically at the same time as their transplant surgery. That is the finding of a Mayo Clinic study recently published in the American Journal of Transplantation. (2020-09-29)

Heart disease in young people may be linked to diabetes exposure in the womb
Heart disease in young adults and teenagers may be related to exposure to diabetes in the womb, according to new research published in CMAJ (Canadian Medical Association Journal) http://www.cmaj.ca/lookup/doi/10.1503/cmaj.190797. (2020-09-28)

Mapping the human heart, cell by cell
Scientists have mapped and described the function of cells in six regions of the adult heart, providing a new foundation for studying heart disease. (2020-09-24)

New 'atlas' of human heart cells first step toward precision treatments for heart disease
Scientists have for the first time documented all of the different cell types and genes expressed in the healthy human heart, in research published in the journal Nature. Cardiologists from the Mazankowski Alberta Heart Institute at the University of Alberta joined teams from Cambridge, Boston and Berlin to use state-of-the-art analytical techniques to sequence the ribonucleic acids (RNA) in nine types of single cells from six regions of the heart. (2020-09-24)

Analysis reveals heart-related side effects of hydroxychloroquine and chloroquine
As the antimalarial drugs hydroxychloroquine and chloroquine have drawn attention as potential therapies for COVID-19 and are being widely used off-label, it's now more important than ever to have a thorough assessment of the safety of these medications. A recent analysis published in the British Journal of Clinical Pharmacology provides new insights. (2020-09-23)

Study finds lung transplant patients not given antifungal preventive drugs have higher risk of death
Antifungal preventive medications reduce mortality risk by half in the first year following lung transplantation, according to Mayo Clinic research involving 667 patients who received lung transplants from 2005 to 2018. (2020-09-23)

Study finds gut microbiome plays important role in sleep regulation
Obstructive sleep apnea (OSA) affects more than one billion people worldwide. Evidence suggests OSA can alter the gut microbiome (GM) and may promote OSA-associated co-morbidities, including diabetes, hypertension and cognitive problems. Researchers from the University of Missouri School of Medicine have discovered how OSA-related sleep disturbances affect the gut microbiome in mice and how transplanting those gut bacteria into other mice can cause changes to sleep patterns in the recipient mice. (2020-09-23)

Study identifies weight-loss threshold for heart health in patients with obesity, diabetes
A Cleveland Clinic study shows that 5 to 10 percent of surgically induced weight loss is associated with improved life expectancy and cardiovascular health. In comparison, about 20 percent weight loss is necessary to observe similar benefits with a non-surgical treatment. The findings also show that metabolic surgery may contribute health benefits that are independent of weight loss. The study is published in the October issue of Annals of Surgery. (2020-09-23)

Grappling with questions about how COVID-19 can affect the heart
For an issue once expected to occur mostly in patients with severe COVID-19, heart conditions following SARS-CoV-2 infection are much more prevalent, writes Eric Topol in a Perspective. (2020-09-23)

Yale succeeds with a more inclusive approach to heart transplants
Doctors at Yale New Haven Hospital used a more aggressive selection process to more than quadruple the number of heart transplants performed there while maintaining positive patient outcomes, according to a new study. (2020-09-18)

Heart transplants from severely obese donors show comparable outcomes for patients
An analysis of more than 26,000 heart transplant patients found that recipients of hearts from donors with severe obesity had similar post-transplant outcomes to recipients with non-obese donors. Nearly 40% of US adults are obese, and the prevalence of severe obesity has doubled over the past 15 years. (2020-09-16)

Tailored education system to benefit kidney transplant patients
Researchers find their computer-tailored education system, 'Your Path to Transplant' increases knowledge and readiness to pursue kidney transplant. (2020-09-16)

Generation of three-dimensional heart organoids
Researchers from Tokyo Medical and Dental University (TMDU) engineered three-dimensional functional heart organoids resembling the developing heart. By exposing mouse embryonic stem cells to two key proteins during heart development, the researchers were able to form heart organoids with structural, functional, and molecular similarities to the embryonic heart during development. This method could be used to study heart development and to screen for novel drugs against heart disease. (2020-09-16)

Multi-institutional collaborative effort to create a cell map of the human heart
Researchers from the? Masonic Medical Research Institute (MMRI), the Precision Cardiology Lab (PCL) of the Broad Institute at MIT and Harvard, Bayer USA, Massachusetts General Hospital, and University of Pennsylvania collaborated to uncover some pressing questions about the biology of the heart. While understanding the mechanisms causal to human heart disease remain active areas of research for many scientists, important knowledge gaps about its composition and function remain unknown. (2020-09-16)

A 'cell-less' therapy may regenerate heart tissue without cell transplant risks
Ling Gao and colleagues have developed a strategy that uses exosomes - tiny membrane-bound sacs secreted by cells - to mimic the heart-regenerating effects of cardiac cell transplants, while potentially avoiding risks associated with whole-cell transplants. (2020-09-16)

Newly discovered mechanism regulates myocardial distensibility
A team of researchers headed by M√ľnster University physiologist Prof. Wolfgang Linke has shown that oxidative stress, in combination with the extension of the heart walls, triggers a change in cardiac stiffness. A key role is played by the giant protein titin. This newly discovered mechanism is relevant, for example, in cases of an acute heart attack or chronic heart disease. The results have been published in the journal 'PNAS'. (2020-09-15)

CNIC researchers discover a cell-cleaning system that keeps hearts healthy
The study published in Cell shows that macrophages, a type of immune cell, help cardiac cells to get rid of their waste material, and that this maintains the metabolic and contractile properties of the heart. (2020-09-15)

Imaging agent developed at Washington University spotlights inflammation
Researchers at Washington University School of Medicine in St. Louis have created a new PET imaging agent that detects signs of inflammation. Such a tracer could aid diagnosis and study of diseases ranging from cardiovascular disease to cancer to COVID-19. (2020-09-14)

Depression risk detected by measuring heart rate changes
For the first time doctors have shown that measuring changes in 24-hour heart rate can reliably indicate whether or not someone is depressed. In practical terms, this may give clinicians an objective ''early warning'' of potential depression, as well as a rapid indication whether or not treatment is working, so opening the way to more rapid and responsive treatment. (2020-09-11)

Oxygen-releasing bioink for 3D bioprinting
Newly developed bioink enhances the ability of implanted cells to grow and regenerate new tissue (2020-09-09)

UC Davis researchers find a way to help stem cells work for the heart
Blocking an enzyme linked with inflammation makes it possible for stem cells to repair damaged heart tissue, new research from UC Davis Health scientists shows. (2020-09-09)

Fighting cardiovascular disease with acne drug
Researchers from the European Molecular Biology Laboratory (EMBL) in Heidelberg and Stanford University have found the cause of dilated cardiomyopathy - a leading cause of heart failure - and identified a potential treatment for it: a drug already used to treat acne. The study was published on 8 September in Cell Reports. (2020-09-08)

Mini-organs could offer treatment hope for children with intestinal failure
Pioneering scientists at the Francis Crick Institute, Great Ormond Street Hospital (GOSH) and UCL Great Ormond Street Institute of Child Health (ICH) have grown human intestinal grafts using stem cells from patient tissue that could one day lead to personalised transplants for children with intestinal failure, according to a study published in Nature Medicine. (2020-09-07)

Key priorities for transplant and living donor advocacy during COVID-1
Researchers describe ways to achieve optimal patient advocacy for kidney recipients and donors during the COVID-19 pandemic and beyond. (2020-09-04)

Tiny biological package gets drug right to the 'heart' of transplant rejection
For patients who receive a heart transplant in the near future, the old adage, 'Good things come in small packages,' may become words to live by. In a recent study, researchers at Johns Hopkins Medicine and the National Cancer Institute (NCI) demonstrated in mice that they can easily deliver a promising anti-rejection drug directly to the area surrounding a grafted heart by packaging it within a tiny three-dimensional, protein gel cocoon known as a hydrogel. (2020-09-03)

Kidneys infected with hepatitis C can be safely transplanted into healthy recipients
Kidneys infected with hepatitis C can be safely transplanted into healthy recipients (2020-09-02)

Architecture of the heart different between women and men and with age
Differences in the shape and texture of men and women's hearts could potentially explain why their risk of heart disease differs, according to research funded by the British Heart Foundation (BHF). The findings are being presented at the European Society of Cardiology (ESC) Congress. (2020-08-31)

EMPEROR-Reduced meets primary endpoint in heart failure with reduced ejection fraction
Empagliflozin reduces the risk of cardiovascular death or hospitalisation for heart failure in patients with heart failure and a reduced ejection fraction. That's the finding of the EMPEROR-Reduced trial presented in a Hot Line session today at ESC Congress 2020. (2020-08-31)

Microgel immuno-acceptance method could improve pancreatic islet transplant success
Researchers at the Georgia Institute of Technology and University of Missouri have developed a new microgel drug delivery method that could extend the effectiveness of pancreatic islet transplantations -- from several years to possibly the entire lifespan of a recipient. (2020-08-31)

Risk of heart attacks halves in patients with diabetes in 15 years
Dramatic reductions in the risk of heart attacks in patients with diabetes coincides with major increases in the use of preventive medications. That's the finding of late breaking research presented today at ESC Congress 2020. 'Our results suggest that when patients are diagnosed with type 2 diabetes, starting medications to prevent cardiovascular disease has a substantial impact on the risk of heart attacks and premature death,' said principal investigator Dr. Christine Gyldenkerne of Aarhus University Hospital, Denmark. (2020-08-29)

Vaccines against respiratory infections linked with less heart failure deaths
Influenza and pneumonia vaccinations are associated with fewer hospital deaths in patients with heart failure. That's the result of a study in nearly 3 million Americans released today at ESC Congress 2020. One out of five individuals will develop heart failure in their lifetime. An estimated 26 million people are affected worldwide. (2020-08-28)

Rejuvenating old organs could increase donor pool
Investigators from Brigham and Women's Hospital are leading efforts to breathe new life into older organs by leveraging a new class of drugs known as senolytics, which target and eliminate old cells. (2020-08-27)

Gout treatment may aid patients with congenital heart disease
A drug used to treat gout, probenecid, may improve heart function in individuals with a particular heart defect, according to results from a small pilot study run by a University of Cincinnati researcher. Individuals with congenital univentricular circulation ran better and their heart performed better while taking probenecid. The change was small partially because of the small number of study participants. (2020-08-27)

Estrogen may lessen severity of COVID-19 symptoms in women, study says
Why are men at greater risk than women for more severe symptoms and worse outcomes from COVID-19 regardless of age? (2020-08-27)

Study confirms link between influenza, heart complications
The link between influenza and serious heart conditions just grew stronger. A CDC study looking at more than 80,000 adult patients hospitalized with flu over eight seasons found that sudden, serious heart complications were common, occurring in 12% of patients, or 1 in 8. The study, published Aug. 25 in the Annals of Internal Medicine, underscores the importance of getting a flu shot early, and the impact of respiratory infections on the heart. (2020-08-27)

Link between cognitive impairment and worse prognosis in heart failure patients
Heart failure is an endemic disease affecting 250 000 Swedes. Despite new treatments such as modern medicines and defibrillators, the mortality rate is still high and the prognosis worse than for certain cancers. A new study from Lund University in Sweden now shows a link between cognitive impairment and an increased risk for rehospitalisation, or an early death, in heart failure patients. (2020-08-26)

Study shows socioeconomic status linked to heart failure mortality in United States
A variety of treatments exist to address heart failure, yet it continues to carry a poor prognosis. A new study from University Hospitals showed that a person's address can help predict their chance of mortality from heart disease. (2020-08-25)

Less aggressive treatment better for heart patients who go into shock
Less is sometimes more when treating heart patients who go into shock after a heart attack. (2020-08-24)

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