Current Heart Transplant News and Events | Page 24

Current Heart Transplant News and Events, Heart Transplant News Articles.
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BODE may overestimate transplant benefit in COPD patients
In a new study published in the journal CHEST®, researchers aimed to determine if patients selected as transplant candidates have a better survival rate than the BODE score indicates. (2018-03-06)

Cancer stem cells, allies of the tumor and enemies of the patient
Research results point to a therapeutic value for the protein (Ahr) because controlling it might repress the pluripotency of the cancer stem cell and reduce the malignity of the tumour. Indeed, different naturally-occurring molecules have been identified that modulate the activity of this protein in specific ways. In addition, the dioxin receptor might also facilitate the development of tools for the prognosis and evolution of the types of cancer in the study, hepatocellular carcinoma and melanoma. (2018-03-05)

New research showed better survival outcomes in one type of heart failure
A joint 7-year cohort study in both Singapore's and New Zealand's hospitals, revealed answers to key questions about the epidemiology of heart failure. The study set out how two distinct forms of heart failure previously considered similar in prevalence and risk of death, are in fact very different. (2018-03-02)

Inflammatory bowel disease increases likelihood of a heart attack
An analysis of medical-record data from more than 17.5 million patients found that people with inflammatory bowel disease (IBD) are at elevated risk for a heart attack, regardless of whether or not they have traditional risk factors for heart disease such as high cholesterol, high blood pressure and smoking. People between the ages of 18 and 24 are at the highest risk, according to research presented at the American College of Cardiology's 67th Annual Scientific Session. (2018-03-01)

Ethnic differences in need for heart pacemakers may have genetic link
Evidence suggests South Asian people are less likely to require a pacemaker for abnormally low heart rate than white people of European origin. (2018-03-01)

Prediabetes patients at heightened risk for cardiovascular and chronic kidney diseases
Researchers at the Emory Rollins School of Public Health and US Centers for Disease Control and Prevention have found that high proportions of patients with prediabetes are at substantial risk for cardiovascular disease and chronic kidney disease. (2018-03-01)

Higher waist and hip measures may add up to greater risk for heart attack among women
Higher waist and hip size are more strongly associated with heart attack risk than overall obesity, especially among women, according to research in Journal of the American Heart Association, the Open Access Journal of the American Heart Association/American Stroke Association. (2018-02-28)

Aspirin lowers risk of death for patients with diabetes, heart failure
For people living with both Type 2 diabetes and heart failure, taking an aspirin each day appears to lower the risk of dying or being hospitalized for heart failure, according to research being presented at the American College of Cardiology's 67th Annual Scientific Session. But the data also reveal aspirin use may increase the risk of nonfatal heart attack or stroke, a somewhat contradictory finding that surprised researchers. (2018-02-28)

Getting flu vaccine cuts risk of death by half in people with heart failure
For people with heart failure, getting a seasonal influenza (flu) vaccine in a given year was associated with a 50 percent drop in the risk of death during flu season and a 20 percent drop in the risk of death during the rest of the year, according to research presented at the American College of Cardiology's 67th Annual Scientific Session. (2018-02-28)

Breast cancer and lymphoma treatments save lives, but may make heart failure more likely for some
Patients with a history of breast cancer or lymphoma were more than three times as likely to develop heart failure--a condition in which the heart can't pump enough blood to meet the body's needs -- compared with a similar group of patients who did not have cancer, according to data being presented at the American College of Cardiology's 67th Annual Scientific Session. (2018-02-28)

Internet search trends mirror heart disease patterns
Search engine queries related to common heart disease symptoms track closely with geographic and seasonal trends for coronary heart disease hospitalizations, according to research being presented at the American College of Cardiology's 67th Annual Scientific Session. (2018-02-28)

Heart failure more likely for some breast cancer and lymphoma survivors
Patients who were treated for breast cancer or lymphoma are more than three times at risk for developing congestive heart failure, compared with patients who did not have cancer. Congestive heart failure is when the heart muscle does not pump blood as well as it should. This research is being presented at the American College of Cardiology's 67th Annual Scientific Session. (2018-02-28)

3-D simulations reveal synergistic mechanisms of the human heart
In a new study published in EPJ E, Valentina Meschini from the Gran Sasso Science Institute, L'Aquila, Italy and colleagues introduce a new model that examines the mutual interaction of the blood flow with the individual components of the heart. Their work stands out by offering a more holistic and accurate picture of the dynamics of blow flow in the left ventricle, which could give clues to better prevention of cardiac conditions. (2018-02-28)

'Obesity paradox' debunked
A new study debunks the 'obesity paradox,' a counterintuitive finding that showed people who have been diagnosed with cardiovascular disease live longer if they are overweight or obese compared with people who are normal weight at the time of diagnosis. Obese people live shorter lives and have a greater proportion of life with cardiovascular disease, the study reports. (2018-02-28)

Researchers identify the types of genetic mutations associated with nephrotic syndrome
By analyzing the most common genetic variants, Brazilian scientists aim at improving diagnosis nad treatment for the disease, which presents high resistance to drugs as well as relapse in post-transplant scenario. The work made possible an in-depth study of the proteins involved in the glomerular filtration barrier, a structure which is damaged by the syndrome. (2018-02-28)

Implantable machines measure heart function
Scientists have devised a method to obtain critical information about cardiac function -- using machines that help failing hearts circulate blood. (2018-02-28)

Shared decision-making between patients and clinicians can result in better choices
As more and more older patients are offered advanced treatments for chronic diseases, including surgeries and implantable devices, new questions have arisen over how these decision are made. (2018-02-27)

Helpful, hopeful news for bone marrow transplant patients
Research published online by The Lancet Haematology and co-led by Kirsten M. Williams, M.D., suggests that a new imaging agent can safely show engraftment as early as days after transplant--giving a helpful and hopeful preview to patients and their doctors. (2018-02-27)

Impact of misunderstanding genetic tests for heart conditions
Patients who undergo genetic testing for inherited heart disease need to be better informed to know how to interpret the results and understand the impact the results will have on their life, a University of Sydney study has found. (2018-02-23)

UCLA scientists use color-coded tags to discover how heart cells develop
UCLA researchers used fluorescent colored proteins to trace how cardiomyocytes -- cells in heart muscle that enable it to pump blood -- are produced in mouse embryos. The findings could eventually lead to methods for regenerating heart tissue in human adults. (2018-02-22)

Therapy for muscular dystrophy-caused heart failure also improves muscle function in mice
Injections of cardiac progenitor cells help reverse the fatal heart disease caused by Duchenne muscular dystrophy and also lead to improved limb strength and movement ability, a new study shows. The study, published today in Stem Cell Reports, showed that when researchers injected cardiosphere-derived cells (CDCs) into the hearts of laboratory mice with muscular dystrophy, heart function improved along with a marked increase in exercise capacity. (2018-02-22)

Beetroot juice supplements may help certain heart failure patients
Beetroot juice supplements may help enhance exercise capacity in patients with heart failure, according to a new proof-of-concept study. Exercise capacity is a key factor linked to these patients' quality of life and even survival. (2018-02-22)

Kids with chronic kidney disease have lower IQs and poorer educational outcomes
Children with chronic kidney disease (CKD) have lower IQs and poorer educational outcomes than healthy children a new review of evidence led by University of Sydney scholars reveals. (2018-02-22)

Study shows age doesn't affect survival in patients with non-Hodgkin lymphoma after HCT
Results from a retrospective study presented at the 2018 BMT Tandem Meetings dispute age as a limiting factor to transplant eligibility, showing no differences in 4-year outcomes for patients older or younger than age 65. (2018-02-21)

Treating sleep-disordered breathing may have cardiovascular benefits for heart failure patients
Severe sleep-disordered breathing is linked with stiffening of the arteries' walls and may be related to the development of heart failure, according to a recent study in ESC Heart Failure, a journal of the European Society of Cardiology. (2018-02-21)

Minimising risks of transplants
A bone marrow transplant is often the only therapy available to save leukaemia patients, but the risk of complications is high. Nearly half of all patients experience an unwanted reaction of their immune system, which often attacks their skin and liver and in up to 50 percent of cases the intestines. Researchers at Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU) have succeeded in deciphering what causes this in some instances life-threatening inflammation of the intestines. (2018-02-21)

Iron triggers dangerous infection in lung transplant patients, Stanford-led study finds
Researchers at the Stanford University School of Medicine have identified elevated tissue iron as a risk factor for life-threatening fungal infections in lung transplant recipients. (2018-02-21)

A drug long used to treat gout may help adult heart failure patients
Researchers at the University of Cincinnati (UC) College of Medicine have shown that probenecid, a drug long used to treat gout, may be able to improve heart function in adult patients who experience heart failure. (2018-02-20)

Study shows higher risk of Dementia for adults with congenital heart disease
A new study is believed to be the first to show a higher risk of dementia in adults who were born with heart disease. The study of more than 10,000 adult with congenital heart disease (CHD) in Denmark discovered a particularly increased risk for early dementia in middle-age adults. (2018-02-20)

Women once considered low risk for heart disease show evidence of previous heart attack scars
Women who complain about chest pain often are reassured by their doctors that there is no reason to worry because their angiograms show that the women don't have blockages in the major heart arteries, a primary cause of heart attacks in men. But a National Institutes of Health study shows that about 8% of those women actually have scars on their heart that indicate they experienced a heart attack. (2018-02-20)

Resolvin D-1 limits kidney damage after heart attacks
A heart attack triggers an acute inflammatory response at the damaged portion of the heart's left ventricle. If the inflammation lingers, it can lead heart failure. The inflammation can also claim another victim -- the kidneys. New research shows that a bioactive compound called resolvin D-1, injected as a therapeutic dose, is able to limit this collateral damage in the kidneys, as tested in an animal model. This suggests potential application to the clinical setting. (2018-02-20)

Rapid pollution increases may be as harmful to the heart as absolute levels
Rapid increases in pollution may be as harmful to the heart as sustained high levels, according to research published today in the European Journal of Preventive Cardiology,1 a European Society of Cardiology journal. The authors urgently call for confirmatory studies as even residents of clean air cities could be at risk. (2018-02-15)

Study maps molecular mechanisms crucial for new approach to heart disease therapy
In this study, published in Cell Reports, two labs at UNC and a group at Princeton University reprogrammed ordinary cells called fibroblasts into new and healthy heart muscle cells, and recorded changes that appear to be necessary for this reprogramming. (2018-02-13)

Alternatives to whole liver transplants for children have become safer, study finds
In a new Johns Hopkins study of patient and graft survival trends for pediatric liver transplant recipients between 2002 and 2015, researchers found that outcomes for alternatives to whole liver transplantation (WLT), such as splitting a liver for two recipients or using a part of a liver from a living donor, have improved significantly. (2018-02-12)

A new tool for improving uterine transplant surgery
Future Science Group (FSG) today announced the publication of an article in Future Science OA demonstrating the first use of multispectral imaging in gynecology, in a uterine transplant setting. (2018-02-12)

Obesity, other risks play large role in sudden cardiac arrest among the young
Obesity and other common cardiovascular risk factors may play a greater role in sudden cardiac arrest among younger people than previously recognized, underscoring the importance of earlier screening, a Cedars-Sinai study has found. (2018-02-12)

Search for genetically stable bioengineered gut and liver tissue takes step forward
Before medical science can bioengineer human organs in a lab for therapeutic use, two remaining hurdles are ensuring genetic stability -- so the organs are free from the risk of tumor growth -- and producing organ tissues of sufficient volume and size for viable transplant into people. Scientists report in Stem Cell Reports achieving both goals with a new production method for bioengineered human gut and liver tissues. (2018-02-08)

CNIC scientists describe the mechanism of heart regeneration in the zebrafish
A new study published in Nature Communications describes a high level of plasticity among different cell populations in the regenerating zebrafish heart (2018-02-08)

Detecting and treating dnDSA early preserves allograft function
Monitoring and treating de novo donor-specific antibodies before they could cause graft damage helped to decrease dnDSA in a majority of pediatric kidney transplant recipients at Children National Health System and prevented graft failure in the first few years. (2018-02-05)

Moffitt researchers identify new target to reduce risk of GVHD
Moffitt Cancer Center researchers are trying to identify new drug targets to reduce the risk of GVHD. Their new study, published last week in the Proceedings of the National Academy of Sciences, shows a drug that targets the protein JAK2 may reduce the risk of GVHD. (2018-02-05)

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