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Pain, itself, elicits pain relief, and does so through 'reward' pathway
Researchers have long known that the body can activate its own form of pain relief in response to painful stimuli. Now, UC San Francisco investigators have determined that, in rats, this long-lasting relief is produced by the brain's (1999-08-15)

Drug dependence: Towards a new treatment?
A new compound has proved capable of reducing drug seeking in cocaine-dependent rats. This compound might help addicts to attenuate their frantic drug-seeking behavior and to reduce the risk of relapse after withdrawal. The effect might extend beyond cocaine to other forms of dependence. (1999-07-21)

U.S. In The Midst Of A Heroin Epidemic, But Many Overdose Deaths Can Be Prevented
The number of heroin overdoses is increasing across the U.S. at an alarming rate, but many of the related deaths are preventable, according to a new report. (1999-04-06)

Higher Doses Of Methadone May Do The Trick, New Study Says
Methadone, the granddaddy of replacement treatments for addiction to heroin and other opioid drugs, has been available for 30 years. Surprisingly, studies that show clearly which doses are best at keeping patients from using illegal opioids are rare. (1999-03-17)

Interstate Highway 95 Contributes To North Carolina Syphilis Spread
CHAPEL HILL - Interstate 95, which snakes through the eastern third of North Carolina, not only promotes rapid movement of vehicles between the North and South, it also facilitates the spread of syphilis, according to a new study. (1999-03-01)

US Drug Policy Failing
A drug policy based on prohibition and intensive enforcement has generated an epidemic of adverse health outcomes that disproportionately affects African Americans, according to an article published in the Jan/Feb issue of Public Health Reports. Ernest Drucker, Ph.D., Albert Einstein College of Medicine, reports that despite some declines in drug use since 1979, cocaine-related and heroin-related emergency department visits and overdose deaths have climbed sharply. (1999-01-11)

Alcoholic's Adversary: Study Pinpoints Brain Molecule That Is Key For Alcohol Preference And Sensitivity
For the first time, animal research clearly demonstrates that a brain element known to produce pleasure, the D2 dopamine receptor, plays a critical role in alcohol consumption. (1998-10-20)

Hopkins Study Shows Languishing Addictions Drug Really Works
A longer-acting alternative to methadone that never quite caught on following its FDA approval in 1993 may now greatly increase the number of addicts who stick with treatment, thanks to a new Johns Hopkins study. (1998-08-11)

UF Psychiatrists Use Antidepressants To Treat Smoking Addiction
University of Florida psychiatrists are wielding new weapons in the war against nicotine addiction: antidepressants. Part of a three-pronged approach that may include nicotine replacement therapy and counseling, the idea is to help smokers kick the habit by tackling addiction at its root. (1998-04-23)

Is Ritalin As Effective--And As Harmless--As It Could Be?
Ritalin, the treatment of choice for an estimated 2 million or more children suffering from attention deficit hyperactivity disorder, could be more effective and cause fewer side-effects if it were administered as a single compound rather than as a mixture, say chemists at Brookhaven National Laboratory. (1998-03-29)

NIH Consensus Panel Recommends Expanding Access To And Improving Methadone Treatment Programs For Heroin Addiction
A consensus panel convened by the National Institutes of Health today strongly recommended broader access to methadone maintenance treatment programs for people who are addicted to heroin or other opiate drugs and that the Federal and State regulations and other barriers impeding this access be eliminated. (1997-11-19)

Excess dopamine D4 receptor (D4DR) Exon III seven repeat allele in opioid dependent subjects
Both twin studies in humans and studies on the pharmacogenetics of opioid addiction in rodents point to a role for heritability as a contributing factor in the development of drug dependence. This study may be the first to show a significant link betweena specific genetic polymorphism and opioid dependence in humans (1997-05-01)

Postmature Infants Not As Easily Calmed As Other Newborns
Though as many as 10 percent of newborns are born with a condition caused by postmaturity, little is known about the social or emotional implications of their condition. Now psychologists at Johns Hopkins and the University of Maine have learned that these Clifford's postmaturity syndrome infants are not as easily calmed as most other newborns (1996-11-27)

PET Scans Show Link Between Cocaine And Heroin Addictions
Researchers at Johns Hopkins and the National Institute on Drug Abuse have the first direct evidence that the brain's own natural opiate system is deeply involved in cocaine addiction and craving. (1996-11-06)

Brookhaven National Lab Named Drug Addiction Study Center
The biochemical origins of drug addiction, and possible ways to block those addictions, will be the focus at a new study center using PET imaging at the U.S. Department of Energy's Brookhaven National Laboratory.To be funded by White House Drug Policy Office, NIH Drug Institute & DOE (1996-10-15)

OHSU Scientists Discover Brain Signaling System That Modulates Sensitivity To Paing System
Scientists have discovered a brain signaling system that opposes the action of opioid drugs like morphine. Their findings appear in the Oct. 3, 1996 issue of the journal Neuroscience. The paper describes the action of a natural brain chemical called orphanin FQ, or simply OFQ, that opposes the effects of opioids. (1996-10-01)

Drug Treatment Programs Don't Work
Drug rehabilitation programs don't work, says a professor of psychology at Oregon State University who has studied various approaches to this problem all over the world. His message to the countries he has worked in -- you can invest billions of dollars in drug treatment programs with very little effect. In the long run, the money would be better spent on prevention through education (1996-05-30)

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