Current Herpes News and Events | Page 15

Current Herpes News and Events, Herpes News Articles.
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Herpes virus shows promise in HIV vaccine research
Two Harvard Medical School researchers working toward an HIV vaccine are yielding promising results using a novel viral vector known for its longevity, according to a study in the September Journal of Virology. (2000-08-31)

Scientists record movement of herpes simplex virus in nerve cell
A team of scientists led by Elaine Bearer of Brown University are the first to observe and record the movement of the herpes simplex virus within a living a nerve cell. The research was performed at Brown and at the Marine Biological Laboratory at Woods Hole, Mass., using squid taken from local waters. (2000-07-02)

New evidence found linking herpes and Alzheimer's
Researchers have long suspected a connection between the herpes virus and Alzheimer's disease. A new study provides a potential explanation that could lead to development of a vaccine to prevent the disease or new drugs to treat it, according to the researchers. The study appears in the May 16 issue of Biochemistry, a peer-reviewed publication of the American Chemical Society, the world's largest scientific society. (2000-05-10)

Novel antiviral drug concept targets number of human viruses
In laboratory studies, an entirely new approach to antiviral drug development is showing remarkable effectiveness. The strategy targets viruses at such a fundamental level that it may prove useful against a wide array of viruses. And, because the approach attacks viruses indirectly, viral drug resistance is extremely unlikely to develop. (2000-04-20)

People unknowingly spread epidemic of sexually transmitted disease
An estimated one out of four Americans already has genital herpes caused by herpes simplex virus type 2 (HSV-2), but the vast majority don't know it. A University of Washington study overturns a myth and reveals that people who appear asymptomatic are just as likely to be infectious as others. (2000-03-21)

Oregon Health Sciences University researchers find a genetic link between vascular disease and a common human herpes virus
OHSU researchers have found a connection between human cytomegalovirus and vascular disease. The cytomegalovirus- linked vascular disease surfaces in patients who have undergone an organ transplant or angioplasty procedure.Cytomegalovirus has already infected up to 50 percent of the adult population in the United States. (1999-11-23)

Study explores how people react to learning they have genital herpes
Thanks to new tests coming on the market, a flood of people may learn that they are part of a huge epidemic of genital herpes. A University of Washington scientist is leading a team that will study how health care professionals can help educate people about the disease and prevent it. (1999-11-09)

The American Association of Pharmaceutical Scientists releases latest findings at Annual Meeting
More than seven thousand pharmaceutical scientists from around the world will gather in New Orleans November 14-18 to share the latest scientific research--from AIDS-preventing contraceptives to aspirin-linked disease. Below are summaries of papers to be presented at the AAPS Annual Meeting (1999-11-04)

University of Pittsburgh study suggests herpes-delivered gene could provide long-term, systemic therapy for peripheral neuropathy
University of Pittsburgh investigators report important advances with a gene vector system that could eventually aid the successful clinical delivery of a therapeutic gene for peripheral neuropathy. They are presenting their findings Thursday, Oct. 28 at the Society for Neuroscience meeting in Miami. (1999-10-27)

Study examines STDs among women-to-women sex partners
Researchers at the University of Washington have begun the first extensive study of lesbian and bisexual women and sexually transmitted diseases. Researchers are discussing some of their tentative findings on a new Web site, http://www.lesbianstd.com, to attract more volunteers. (1999-10-19)

New molecular clues to herpes control
A study at the University of North Carolina at Chapel Hill may have identified a new way to halt herpes simplex virus in its molecular tracks. (1999-10-13)

Rescuing brain cells in stroke patients from the brink of suicide
For several days after a patient suffers a stroke, brain cells are bombarded with molecular 'pro-death' signals carrying such bad news about the brain environment that cells are tempted to commit suicide. University of Rochester scientists have enlisted an unlikely ally, the herpes virus, to help brain cells choose life. (1999-08-23)

Drug users, Native Americans susceptible to infectious diseases
A virus found primarily in injection drug users and a small number of Native Americans may increase the incidence of infectious diseases, according to a multi-center, longitudinal study headed by the University of California, San Francisco. (1999-07-14)

Single amino acid change in herpes virus prevents it from infecting neurons
Researchers at the University of Chicago have found that a single amino acid change in a viral protein called ICP0, stops the herpes virus from entering the nervous system. The finding provides clear evidence of how viruses usurp the machinery of the cells they infect, and reveals a potential new target for a herpes vaccine or future therapies. (1999-07-09)

Gene therapy could treat diabetic incontinence, suggest early studies at University of Pittsburgh
University of Pittsburgh researchers have successfully controlled incontinence in animals with diabetes using a modified herpes virus to shuttle a therapeutic gene into damaged bladder nerves. The findings, which could eventually benefit patients, are being presented June 10 at the American Society of Gene Therapy meeting in Washington, D.C. (1999-06-10)

Research Findings Suggest Potent, Broad-Spectrum Antiviral Activity For Vertex's Investigational IMPDH Inhibitor VX-497
The investigational drug VX-497 may have potent, broad- spectrum antiviral activity, according to laboratory results from Vertex Pharmaceuticals being presented at ICAR. VX-497's activity against viruses in cell culture was compared to ribavirin, both alone and in combination with interferon-alpha. VX-497 Phase II clinical trials are underway for HCV and psoriasis. (1999-03-25)

University Of Pittsburgh Involved In First Successful Example Of Gene Therapy For Pain Control
Using a patented gene vector developed by the University of Pittsburgh, a University of South Carolina-led team is the first to show that gene therapy blocks certain pain responses in animals. This landmark study is published in the March 16 issue of the Proceedings of the National Academy of Sciences. (1999-03-16)

Topical Agent Found To Kill Papillomavirus
A common surfactant and detergent found in many shampoos and toothpastes is the first topical microbicidal agent shown to kill animal and human papillomavirus, according to a Penn State researcher. Sodium dodecyl sulfate was found in cell culture and animal testing to inactivate sexually transmitted viruses including HIV,HSV-2 and HPVs. (1999-02-12)

Antibody Revolution Targets STDs, Stomach Viruses, Common Cold
Biophysicists say a new wave of cheap, widely available treatments is coming for ailments ranging from sexually transmitted diseases to the common cold. (1998-12-29)

University Of Chicago Professor Wins $50,000 Bristol-Myers Squibb Award For Distinguished Achievement In Infectious Disease Research
Bernard Roizman, Sc.D., the world's leading expert on herpes simplex virus (HSV), and Joseph Regenstein Distinguished Service Professor in the departments of molecular genetics & cell biology and biochemistry and molecular biology at the University of Chicago, has been named the winner of the eighth annual Bristol-Myers Squibb Award for Distinguished Achievement in Infectious Disease Research. (1998-11-05)

Alzheimers Disease Could Soon Be Treated With Nose Drops
Alzheimer's disease and other neurodegenerative disorders could soon be treated with nose drops. Researchers in Minnesota say that the nasal passage holds great promise for delivering drugs to the brain, as olfactory nerves provide a direct link between the brain and the outside world. (1998-09-02)

Social Stress Causes Dormant Herpes Virus To Resurface In Mice
New research in mice shows that changes in social interactions can stimulate a dormant herpes virus to resurface. In a series of experiments, 40 percent of mice with latent herpes had their virus reactivated when their social structure was reorganized, leading to conflicts among the mice. (1998-07-31)

Common Anti-Viral Medication Prevents Severe Eye Herpes
A new study led by University of California San Francisco researchers has found that acyclovir, a common anti-viral drug used to treat and prevent genital herpes, can also prevent the recurrence of herpes disease of the eye. (1998-07-29)

New Herpesvirus Receptor Discovered That Allows Entry of Both Herpes Simplex-1And -2 And Animal Herpesviruses Into Human Cells
A new protein has been discovered that provides a pathway for several different types of herpesvirus, including two herpes simplex viruses (HSV), to infect human cells. This protein, called a herpesvirus entry mediator, is the third receptor for HSV to be identified by Northwestern University researchers. (1998-06-04)

New Model Makes It Possible To Predict Emergence Of Antiviral Drug Resistance
Researchers led by a UC San Francisco scientist have developed a model for predicting the emergence of antiviral drug resistance and for identifying the key factors that generate drug resistance. (1998-06-01)

UF Researchers Identify Virus That May Cause Epidemic Disease In Sea Turtles
A unique virus genetically related to human herpes viruses could be linked to a serious tumor epidemic threatening the survival of endangered sea turtles worldwide, according to a team of researchers at the University of Florida College of Veterinary Medicine and the Marathon-based Turtle Hospital who first identified it. (1998-01-23)

New Company To Turn UNC-CH, Army Inventions Into Improved Vaccines
Inventions by microbiologists at the University of North Carolina at Chapel Hill and U.S. Army Medical Research Institute of Infectious Diseases have led to creation of AlphaVax, a new company in Durham. (1998-01-22)

Harvard Medical School Researchers Present Atomic Structure Of DNA-Replicating Enzyme Widely Used In DNA Sequencing
Harvard Medical School researchers have established the 3-D, atom-by-atom structure of a DNA-replicating enzyme at work. This protein, T7 DNA polymerase, is used worldwide to sequence DNA. This structure will be of special interest to researchers who develop drugs targeting DNA replication. Many antiviral drugs, including the AIDS drug AZT and drugs against herpes simplex virus, inhibit DNA polymerase. (1998-01-15)

Gene Therapy Trial Takes Aim At Deadly Brain Cancer
Neurosurgeon David Andrews, M.D., and researchers at Jefferson Medical College of Thomas Jefferson University, Philadelphia, hope to find out if gene therapy is safe and effective in treating glioblastoma, a brain cancer. Jefferson is among 40 centers worldwide participating in perhaps the first organized international gene therapy trial. (1998-01-05)

Targeted Protein Toxin Effective Against Persistent Brain Tumors
Scientists at the National Institutes of Health have developed a new drug that can reduce the size of some persistent brain tumors without causing severe side effects. A report of the first clinical trial of this drug, called transferrin-CRM107, will appear in the December 1997 issue of Nature Medicine. (1997-11-24)

Herpes Virus Strain Identified As A Trigger In Multiple Sclerosis
A strain of reactivated herpes virus may be associated with multiple sclerosis (MS), an autoimmune disorder in which the body attacks its own tissues. Results of a study conducted by scientists at the NINDS in Bethesda, Maryland, add to mounting evidence of the role of viral triggers in MS and may serve as the cornerstone for clinical trials using antiherpetic agents as a treatment. (1997-11-24)

NIH Awards UNC-CH School Of Medicine $6 Million To Set Up Unique Sex Disease Unit
The University of North Carolina at Chapel Hill School of Medicine will establish the nationĀ¹s only clinical trials center devoted exclusively to developing and testing new sexually transmitted disease therapies and prevention methods, medical school officials announced today. (1997-11-06)

OHSU Researchers Discover Host Site, Activation Mechanism For Virus That Causes Birth Defects And Deaths Following Transplant
Researchers at Oregon Health Sciences University, reporting in the October 3 Cell Magazine, have determined the host site and activiation mechanism for human cytomegalovirus (HCMV). HCMV is the leading viral cause of deaths in bone marrow transplant and AIDS patients, and a major viral cause of some birth defects. (1997-10-02)

Acquiring Herpes Late In Pregnancy Brings Special Dangers To The Newborn
While there is never a good time to acquire a herpes infection, contracting the virus late in pregnancy can prove catastrophic for the newborn child, with a high risk of severe brain damage or death from neonatal herpes. (1997-08-19)

New Vaccine Blocks Viral Entry In Cattle, May Have Implications For Human Vaccines
Geoffrey Letchworth, a University of Wisconsin-Madison virologist, has developed an experimental vaccine that may have implications for controlling human viral diseases. Unlike typical vaccines that coax the immune system to fight viruses, Letchworth's new vaccine for bovine herpes virus-1 blocks viruses from even entering the body of cattle (1997-04-17)

Herpes-Based Gene Therapy Is Key To Promising Liver Tumor Vaccine
Physicians from Memorial Sloan-Kettering Cancer Center and the University of Rochester's Cancer Center have created a promising compound that recruits the body's immune system to target and wipe out cancer cells in the liver. In a study with laboratory rats, the majority of animals injected with the vaccine were cancer-free, while similar animals that did not receive the vaccine typically had dozens of tumors. (1997-04-07)

Herpes-Based Gene Therapy Is Key To Promising Liver Tumor Vaccine
Physicians from the University of Rochester's Cancer Center and Memorial Sloan-Kettering Cancer Center have created a promising compound that recruits the body's immune system to target and wipe out cancer cells in the liver. The majority of rats injected with the vaccine were cancer-free, while control animals typically had dozens of tumors (1997-04-03)

Vaccination Can Prevent Death And Disease Without Killing A Virus
Scientists may want to rethink the current theory that to be effective, vaccines must completely eliminate an invading virus. Researchers at the University of Wisconsin Medical School have shown that vaccination can reduce or prevent fatal immune responses to a virus in mice, even though the virus continues to live in the animals. (1996-11-07)

Northwestern Scientists Discover How Herpes Simplex Virus Infects Cells
Researchers at Northwestern University have discovered a human protein that provides a pathway for herpes simplex virus to infect certain types of human cells. This human protein is not only the first (1996-10-31)

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