Current Hormone Therapy News and Events

Current Hormone Therapy News and Events, Hormone Therapy News Articles.
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Study shows new treatment pathway to prevent and treat endometrial cancer recurrence
In a new study led by Yale Cancer Center, researchers demonstrate sex hormones and insulin growth factors are associated with recurrence risk of endometrial cancer. (2021-02-23)

Structured exercise program, not testosterone therapy improved men's artery health
A 12-week, structured exercise program improved artery health and function in men ages 50 to 70 years old who had low to normal testosterone levels before the program began. Adding testosterone therapy to exercise or testosterone therapy alone did not improve artery health or function. (2021-02-22)

Two distinct pathways leading to the development of septic shock pave the way for personalized medicine in sepsis
Diagnostics company SphingoTec GmbH announced today that two distinct processes are involved in the development of septic shock and that SphingoTec's biomarkers for endothelial function (vascular integrity) and cardiovascular depression allow early identification of these underlying mechanisms requiring different interventions. (2021-02-18)

Study finds risk factor for blood clots occurs in more than 10 percent of transgender men using testosterone
A potentially dangerous side effect of testosterone therapy for transgender men is an increase in red blood cells that can raise the risk of blood clots, heart attack or stroke, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2021-02-18)

Physical therapy after c-section improves outcomes
Women who received physical therapy after undergoing a cesarean section had significantly improved outcomes compared to those who did not according to a new study from University of Missouri Health Care. (2021-02-17)

Friends fur life help build skills for life
A new UBC Okanagan study finds children not only reap the benefits of working with therapy dogs-they enjoy it too. (2021-02-17)

Psychotherapy for panic disorder shows positive long-term effects
Psychotherapy for panic disorder produces good results, and the effects are lasting. That is the result from a large long-term study from Lund University in Sweden. Two years after treatment were 70 per cent of the patients clearly improved and 45 per cent were remitted. (2021-02-16)

The body produces new satiety factor during prolonged exercise
Researchers at the University of Copenhagen confirm that the hormone GDF15 is released in response to vigorous exercise, but likely not in sufficient quantity to affect behavior or appetite. These findings add nuance to a hormone that is currently under scrutiny for its potential as an anti-obesity medication. (2021-02-16)

Integrating maths and plant science to explain how plant roots generate a hormone gradient
The research team that developed a biosensor that first recorded that a distinct gradient of the plant growth hormone gibberellin correlated with plant cell size has now revealed how this distribution pattern is created in roots. (2021-02-15)

Chinese people may be more susceptible to obesity-related health risks than other racial, ethnic groups
Chinese people are more likely to face high blood pressure and other health risks as a result of higher body mass index (BMI) and waist circumference than people from other racial and ethnic groups, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2021-02-11)

Genomic test helps estimate risk of prostate cancer metastasis, death
A commercially available genomic test may help oncologists better determine which patients with recurrent prostate cancer may benefit from hormone therapy, according to new research from the Johns Hopkins Kimmel Cancer Center and 15 other medical centers. (2021-02-11)

Using Nature's strategies in the development of new drugs
Dimerization of the human neuropeptides oxytocin and vasopressin can produce new types of bioactive molecules. Such new constructs provide several opportunities to optimize the efficacy of these neuropeptides for therapeutic application. The researchers were inspired for this approach from naturally occurring dimers. (2021-02-10)

Oncotarget: Melatonin increases overall survival of prostate cancer patients
'The results of the use of melatonin drugs in palliative treatment of patients with end-stage prostate cancer are shown' (2021-02-10)

New targets for the development of a drug treatment for obesity and type 2 diabetes
The GIP receptor in the central nervous system plays a crucial role in the regulation of body weight and food intake. This is shown by a recent study by Helmholtz Zentrum M√ľnchen, ETH Zurich and the German Center for Diabetes Research (DZD). The study, which has now been published in 'Cell Metabolism', identifies new targets for the development of a drug treatment for obesity and type 2 diabetes. (2021-02-10)

Signs of burnout can be detected in sweat
EPFL engineers, working in association with startup Xsensio, have developed a wearable system that can continually measure the concentration of cortisol - the stress hormone - in human sweat. Their device can eventually help doctors better understand and treat stress-related conditions like burnout and obesity. (2021-02-05)

Effectiveness of endocrine therapy for breast cancer in men
This randomized clinical trial looked at changes in levels of the hormone estradiol in men with hormone receptor-positive breast cancer after three months of treatment with endocrine therapies. (2021-02-04)

Researchers assess cognitive impairment in patients with breast cancer
A recent analysis of published studies in Psycho-Oncology estimates that one-quarter of adults with breast cancer have cognitive impairment before starting therapy. (2021-02-03)

CO2 laser therapy helps improve sexual function in postmenopausal women with breast cancer
CLEVELAND, Ohio (Feb 3, 2021)--Postmenopausal women often complain of painful intercourse or a lack of desire caused by decreased estrogen levels, which affect vaginal elasticity and lubrication. Survivors of breast cancer typically experience worse symptoms as a result of cancer treatments, and concerns exist regarding hormone therapies. A new study suggests that fractional CO2 laser therapy may help. Study results are published online in Menopause, the journal of The North American Menopause Society (NAMS). (2021-02-03)

Imaging identifies breast cancer patients unlikely to benefit from hormone therapy
Hormone therapy can be very effective for so-called estrogen receptor-positive breast cancer. But it only works for a little more than half of women who receive the treatment. In a small study, researchers at Washington University School of Medicine in St. Louis found that women whose tumors did not respond to a one-day estrogen challenge did not benefit from hormone therapy. The findings could help doctors choose treatments most likely to help their patients. (2021-02-02)

Novel therapy-resistance mechanism promoting the growth of breast cancer brain metastasis
SORLA is a protein trafficking receptor that has been mainly studied in neurons, but it also plays a role in cancer cells. Professor Johanna Ivaska's research group at Turku Bioscience observed that SORLA functionally contributes to the most reported therapy-resistant mechanism by which the cell-surface receptor HER3 counteracts HER2 targeting therapy in HER2-positive cancers. Removing SORLA from cancer cells sensitized anti-HER2 resistant breast cancer brain metastasis to targeted therapy. (2021-01-29)

Addressing health disparities in diabetes requires a broader look at systemic racism
Poor social conditions caused by systemic racism contribute to health disparities in people with diabetes, according to a paper published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2021-01-26)

Gut microbiota reveals whether drug therapies work in inflammatory bowel diseases
A study recently completed at the University of Helsinki indicates that the gut microbiota of patients suffering from inflammatory gastrointestinal disorders can be used to predict whether they will benefit from expensive therapies. The study also confirms the key role of therapies that have a beneficial effect on the gut microbiota in inflammatory bowel diseases. (2021-01-26)

Hypertension symptoms in women often mistaken for menopause
Pregnancy complications and early menopause increase women's future risk of heart disease. Cardiologists, gynaecologists and endocrinologists recommend how to help middle-aged women prevent later heart problems in a European Society of Cardiology (ESC) consensus document published today in European Heart Journal, a journal of the ESC. ''Physicians should intensify the detection of hypertension in middle-aged women,'' states the document. (2021-01-26)

Sunbathing after menopause may be harmful
UV-radiation can affect hormone levels of postmenopausal women negatively and this may contribute to several health issues, according to new research from Kai Triebner, University of Bergen, and colleagues. (2021-01-20)

Bonobos, chimpanzees, and oxytocin
Kyoto University researchers analyze the effects of the hormone oxytocin in our closest primate cousins, bonobos and chimpanzees by tracking their eye movement -- a important indicator of social interaction. Similar to other mammals, oxytocin increases eye contact in bonobos. However, the opposite effect is observed in chimpanzees. Therefore, oxytocin could play a modulating role in the social evolution of the two species. (2021-01-20)

Genome editing to treat human retinal degeneration
Gene editing therapies, including CRISPR-Cas systems, offer the potential to correct mutations causing inherited retinal degenerations, a leading cause of blindness. Technological advances in gene editing, continuing safety concerns, and strategies to overcome these challenges (2021-01-19)

New discovery in breast cancer treatment
Researchers at the University of Adelaide have found new evidence about the positive role of androgens in breast cancer treatment with immediate implications for women with estrogen receptor-driven metastatic disease. (2021-01-18)

FGF23 hormone from red blood cell precursors promotes hematopoietic stem cell mobilization
A Kobe University research group have discovered that fibroblast growth factor-23 (FGF23) produced by erythroblasts (cells that are the precursors of red blood cells) promotes the movement of hematopoietic stem cells into the peripheral blood. It is hoped that this discovery will enable new strategies to be developed for harvesting hematopoietic stem cells from bone marrow transplant donors. (2021-01-18)

Biodistribution of AAV gene transfer vectors in nonhuman primate
The biodistribution of adeno-associated virus (AAV) gene transfer vectors can be measured in nonhuman primates using a new method. The method quantifies whole-body and organ-specific AAV capsids from 1 to 72 hours after administration (2021-01-15)

Plant roots sense compacted soil through gaseous hormone signals
The volatile plant hormone ethylene allows plant roots to sense and avoid compacted soils, researchers report. (2021-01-14)

Nanotechnology prevents premature birth in mouse studies
In a study in mice and human cells, Johns Hopkins Medicine researchers say that they have developed a tiny, yet effective method for preventing premature birth. (2021-01-13)

Endocrine Society recommends government negotiation and other policies to lower out-of-pocket costs
The Endocrine Society is calling on policymakers to include government negotiation as part of an overall strategy to reduce insulin prices in its updated position statement published today in The Journal of Clinical Endocrinology & Metabolism. (2021-01-12)

Treatment for chronic pain must address both physical and social pain
Physical pain and social pain may be more closely related than previously thought. Social pain, which typically results from interpersonal rejection or abuse, has been viewed as a non-medical response to external factors. However, recent research suggests that some physical and social stress responses may arise because of shared processing in the brain. (2021-01-12)

NIH study suggests using cannabis while trying to conceive may reduce pregnancy chances
Women who use marijuana could have a more difficult time conceiving a child than women who do not use marijuana, suggests a study by researchers at the National Institutes of Health. Marijuana use among the women's partners--which could have influenced conception rates--was not studied. (2021-01-11)

Study: New insights on the role of the MLL4 gene in Kabuki syndrome
Research suggests that MLL4 controls the production of neurons that secrete growth hormone-releasing hormone (GHRH) in a part of the brain called the hypothalamus. (2021-01-11)

Levels of stress hormone in saliva of newborn deer fawns may predict mortality
The first-ever study of the levels of the stress hormone cortisol in the saliva of newborn white-tailed deer fawns yielded thought-provoking results that have Penn State researchers suggesting predation is not the only thing in the wild killing fawns. (2021-01-11)

Black people with type 1 diabetes, COVID-19 are four times more likely to be hospitalized for diabetic ketoacidosis
Black and Hispanic people with COVID-19 and diabetes are more likely than Caucasians to die or have serious complications, according to a new study published in the Endocrine Society's Journal of Clinical Endocrinology & Metabolism. (2021-01-07)

Sexual dysfunction hits some women harder than others as they age
Sexual dysfunction often accompanies the menopause transition. Yet, not all women experience it the same. A new study identified the determinants that affect a woman's risk of sexual dysfunction and sought to determine the effectiveness of hormone therapy in decreasing that risk and modifying sexual behavior. Study results are published online in Menopause, the journal of The North American Menopause Society (NAMS). (2021-01-06)

Ibrutinib with rituximab in previously untreated CLL: indication of added benefit over FCR
Ibrutinib with rituximab in previously untreated CLL: indication of added benefit over FCR. The new drug combination prolongs overall survival in patients in good general health. No study data are available for other patient groups. (2021-01-05)

Inflammation from ADT may cause fatigue in prostate cancer patients
Moffitt Cancer Center researchers are investigating whether inflammation in the body, a side effect of ADT, contributes to these symptoms in prostate cancer patients. In a new study published in the journal Cancer, they pinpoint a specific inflammation marker that is associated with increased fatigue in this group of patients. (2021-01-04)

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