Current Hpv News and Events

Current Hpv News and Events, Hpv News Articles.
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Oncotarget: Combination of copanlisib with cetuximab improves tumor response
''These data support further investigation of PI3K inhibition in HNSCC and suggests gene expression patterns associated with PI3K signaling'' (2021-02-10)

Reduced-dose RT with Cisplatin improves outcomes for HPV-associated oropharyngeal carcinoma
A combination of reduced-dose radiotherapy using intensity-modulated radiotherapy (IMRT) combined with concurrent cisplatin met the threshold for disease control and quality of life compared to the standard of care for good-risk patients with HPV-associated oropharyngeal squamous cell carcinoma on the NRG Oncology clinical trial NRG-HN002. (2021-01-29)

The Lancet: Study estimates that, without vaccination against 10 diseases, mortality in children under five would be 45% higher in low-income and middle-income countries
Vaccinations against 10 major pathogens have a substantial impact on public health in low-income and middle-income countries (LMICs), according to new modelling research published in The Lancet. The study estimated that from 2000 to 2019 vaccinations have prevented 37 million deaths, and that this figure will increase to 69 million deaths for the period 2000-2030. Most of this impact is estimated to be among children younger than five years, most notably from measles vaccinations. (2021-01-28)

Massey researchers review geographic factors that affect HPV vaccination rates
A team of researchers from VCU Massey Cancer Center conducted the first-ever systematic review of area-level data reported in the United States between 2006 and 2020 to determine how geography, neighborhoods and sociodemographic factors impact HPV vaccination rates among adolescents and young adults. The study was published in Cancer Epidemiology, Biomarkers and Prevention. (2021-01-22)

Behaviors surrounding oral sex may increase HPV-Related cancer risk
A wide breadth of behaviors surrounding oral sex may affect the risk of oral HPV infection and of a virus-associated head and neck cancer that can be spread through this route, a new study led by researchers at the Johns Hopkins Kimmel Cancer Center suggests. (2021-01-14)

Record drop in cancer mortality for second straight year due to improved lung cancer treatment
Overall cancer death rates in the United States dropped continuously from 1991 through 2018 for a total decrease of 31%, including a 2.4% decline from 2017 to 2018. (2021-01-12)

Higher vaccine rates associated with indicative language by provider, more efficient
New research from Boston Medical Center finds that using clear, unambiguous language when recommending HPV vaccination both increases vaccine acceptance and increases conversation efficiency while preserving patient satisfaction. (2021-01-12)

Timing and intensity of oral sex may affect risk of oropharyngeal cancer
Human papillomavirus (HPV) can infect the mouth and throat to cause cancers of the oropharynx. A new study published early online in CANCER, a peer-reviewed journal of the American Cancer Society, has found that having more than 10 prior oral sex partners was associated with a 4.3-times greater likelihood of having HPV-related oropharyngeal cancer. (2021-01-11)

Oncotarget: PD-1/PD-L1 expression in anal squamous intraepithelial lesions
Dr. Margot Bucau from The Hôpital Bichat-Claude Bernard said, ''Anal intraepithelial neoplasia (AIN) is the precursor lesion for anal squamous cell carcinomas (ASCC). (2021-01-11)

Researchers create comprehensive database of head and neck cancers
Researchers from the Johns Hopkins departments of pathology and oncology, the Johns Hopkins Kimmel Cancer Center, the Johns Hopkins University School of Medicine, and 18 other centers around the U.S. and Poland have clarified the contribution of key cancer-associated genes, proteins and signaling pathways in these cancers, while proposing possible new treatment avenues. (2021-01-07)

Facebook posts help facilitate belief that HPV vaccine is dangerous to health
Social media has a history of being a popular place for sexual health discussions, and the HPV vaccine is one of the most discussed vaccines on the internet. Monique Luisi, an assistant professor in the University of Missouri School of Journalism, suggests some HPV vaccine-related Facebook posts can help facilitate beliefs that the HPV vaccine is dangerous to one's health. She believes it could inform officials for the ongoing COVID-19 vaccine roll out and distribution. (2021-01-05)

Sixfold increase in risk
A research team at the Technical University of Munich (TUM) has quantified the effects of an infection with the Human Immunodeficiency Virus (HIV) on the development of cervical cancer. Their results show that the risk of developing cervical cancer is six times higher in women who are infected with HIV. Southern and Eastern Africa are particularly affected. (2020-12-21)

Increasing HPV vaccine uptake in adolescents
More than 90 percent of human papillomavirus (HPV)-related cancers could be prevented by widespread uptake of the HPV vaccine. Yet, vaccine use in the United States falls short of public health goals. (2020-12-01)

Safety of HPV vaccines in males
A new analysis published in the British Journal of Clinical Pharmacology shows that HPV vaccines are safe and well tolerated in the male population, and the side effects that may occur after immunization are similar in both sexes. (2020-11-04)

Promising breath-test for cancer
The global quest to use a person's breath analysis for rapid, inexpensive and accurate early-stage testing for cancer and other diseases has taken a leap forward. In a new paper in the British Journal of Cancer, Flinders University researchers have reported significant progress in developing a method to test exhaled breath profiles which accurately differentiate head and neck cancer from non-cancer patients. (2020-10-05)

Study shows social media policies can curb HPV vaccine misinformation
A new study led by VCU Massey Cancer Center researcher Jeanine Guidry, Ph.D., compared how HPV vaccination was portrayed on Pinterest before and after the social media platform began moderating vaccine-related content. Findings may help public health officials utilize social media to tackle potentially harmful rhetoric and disseminate trustworthy health information. (2020-10-05)

Impact of HPV vaccination mandates on social inequalities
A postdoctoral researcher at the University of California, Riverside, has discovered Human papillomavirus, or HPV, vaccination mandates fall short of ensuring both higher levels of uptake and equal uptake of the vaccine across socioeconomic and racial-ethnic groups. The findings could help facilitate equal access to and compliance with uptake of COVID-19 vaccines, once they are available. (2020-10-05)

Seven in 10 Americans willing to get COVID-19 vaccine, survey finds
Almost seven in 10 Americans would be interested in receiving a COVID-19 vaccine when one becomes available, according to a new study. But researchers say there are concerning gaps in interest, particularly among Black Americans, who suffer disproportionately from the virus. (2020-09-10)

Young gay men's health care needs not being met
Young gay men who are uncomfortable discussing sexual issues with their primary care providers and experience health care discrimination are less likely to seek coordinated care, leading to missed opportunities for early diagnosis of chronic and mental health issues, according to Rutgers researchers. (2020-08-19)

HPV strains may impact cervical cancer prognosis
An analysis of cervical cancers in Ugandan women has uncovered significant genomic differences between tumours caused by different strains of human papillomavirus (HPV), signifying HPV type may impact cervical cancer characteristics and prognosis. (2020-08-10)

Analysis of Ugandan cervical carcinomas, an aid for understudied sub-Saharan women
Cervical cancer kills more than 300,000 middle-aged women a year, and 19 of the 20 nations with the highest death rates are sub-Saharan countries. Now an international team, including Akinyemi I. Ojesina, M.D., Ph.D., University of Alabama at Birmingham, has published the first comprehensive genomic study of cervical cancers in sub-Saharan Africa, with a focus on tumors from 212 Ugandan patients with cervical cancer. (2020-08-10)

HPV vaccination linked to lower risk of precancerous condition
Vaccination against the human papilloma virus (HPV) reduces the risk of a condition that often leads to cervical cancer, according to an analysis of Danish health registry data. (2020-08-05)

The wrong track: How papillomaviruses trick the immune system
Specific antibodies protect us against viral infections - or do they not? Researchers at the German Cancer Research Center (DKFZ) studied the immune response to papillomaviruses in mice and discovered a hitherto unknown mechanism by which the pathogens outwit the immune system: At the beginning of the infection cycle, they produce a longer version of a protein that surrounds the viral genome. The body produces antibodies against this protein, but they are not effective in fighting the pathogen. (2020-08-04)

American Cancer Society updates guideline for cervical cancer screening
An updated cervical cancer screening guideline from the American Cancer Society reflects the rapidly changing landscape of cervical cancer prevention in the United States, calling for less and more simplified screening. (2020-07-30)

Existing evidence suggests face coverings do not lead to false sense of security
Existing limited evidence suggests that wearing face coverings to protect against COVID-19 does not lead to a false sense of security and is unlikely to increase the risk of infection through wearers foregoing other behaviours such as good hand hygiene, say researchers from the University of Cambridge and King's College London. (2020-07-26)

Parents of 1 in 2 unvaccinated US adolescents have no intention to initiate HPV vaccine
Study results documenting parental hesitancy to begin and complete their child's HPV vaccine series were published in The Lancet Public Health by researchers at The University of Texas Health Science Center at Houston (UTHealth). (2020-07-21)

Scientists find a switch which may make prostate cancer spread
Scientists have found a switch which is associated with prostate cancers spreading or forming metastases (secondary tumours). The researchers caution that this work is still at an early stage, and needs further investigation to see if it applies to all prostate cancers. Up to 15% of patients have high risk prostate cancers, potentially leading to significantly increased mortality over time. The work is presented at the virtual European Association of Urology congress. (2020-07-16)

American Cancer Society updates guideline for HPV vaccination
The American Cancer Society has updated its guideline for HPV vaccination, adapting a 2019 update from the Federal Advisory Committee on Immunization Practices. (2020-07-08)

Study: 'Anti-vaxxers' gain traction against HPV vaccine on Facebook
One of the biggest social media sites -- Facebook -- has allowed ''anti-vaxxers'' to gain a stronger voice against the use of the human papillomavirus, or HPV, vaccine, according to a new study from a media expert at the University of Missouri. (2020-07-08)

AI dual-stain approach improved accuracy, efficiency of cervical cancer screening
In a new study, a computer algorithm improved the accuracy and efficiency of cervical cancer screening compared with cytology (Pap test), the current standard for follow-up of women who test positive with primary human papillomavirus (HPV) screening. The algorithm was developed and the study conducted by investigators at the National Cancer Institute (NCI), part of the National Institutes of Health, in collaboration with researchers from several other institutions. (2020-06-25)

Managing abnormal results on cervical cancer screening: ASCCP issues updated guidelines
Replacing guidelines for managing women with abnormal results on cervical cancer screening test from 2012, new recommendations from ASCCP emphasize more precise management based on estimates of the patient's risk - enabling more personalized recommendations for diagnosis, treatment, and follow-up. The revised guidelines with updated recommendations are now available in the Journal of Lower Genital Tract Disease (JLGTD), official journal of ASCCP. The journal is published in the Lippincott portfolio by Wolters Kluwer. (2020-06-25)

Multilevel interventions improve HPV vaccination rates of series initiation and completion
New research from Boston Medical Center shows that providing education and training to pediatric and family medicine providers about the importance of human papillomavirus (HPV) vaccines, in tandem with healthcare systems changes including starting an HPV vaccination series before the age of 11, improves the overall rate of HPV vaccinations among adolescent patients. HPV vaccinations can help reduce rates of HPV-related cancers, as well as play a role in reducing race- and income-related disparities. (2020-06-15)

Wording of vaccination messages influences behavior
An experiment by Washington State University researchers revealed that relatively small differences in messages influenced people's attitudes about the human papillomavirus or HPV vaccine, which has been shown to help prevent cancer. (2020-06-04)

HPV vaccines that work in US women may miss the target in women from other countries
Most cervical cancers are caused by persistent infection with high-risk human papillomavirus (hrHPV). Different vaccines are available to protect against HPV. Researchers at Dartmouth's and Dartmouth-Hitchcock's Norris Cotton Cancer Center have shown a very different prevalence of hrHPV in Honduras compared to the United States, and concluded that the same vaccination programs that target hrHPV strains in the U.S. may not be as effective in protecting women in other countries from the disease. (2020-06-04)

Trial E3311 validates a less intense treatment for HPV+ throat cancer
A final report of the randomized phase 2 trial E3311 shows transoral robotic surgery followed by low-dose radiation alone is safe in patients with intermediate-risk locally advanced oropharynx cancer. Trial showed outcome similar to surgery with standard-dose radiation. The low-dose radiation helped preserve patients' throat function, potentially sparing them unnecessary short- and long-term toxicities. The results present a promising deintensification approach. (2020-05-13)

World-first saliva test detects hidden throat cancer
A series of saliva HPV tests detected an asymptomatic throat cancer during a trial of a new saliva diagnostic. Further validation studies are needed to confirm this finding. It is a world-first discovery, previously there was no screening test for HPV-DNA oropharyngeal cancers. The patient had surgery in which a 2 mm cancer was removed and has had no recurrence of HPV-DNA in his saliva. (2020-05-11)

Human papillomavirus confers radiosensitivity in oropharyngeal cancer cells
The cover for issue 16 of Oncotarget features Figure 6, 'Radiation-induced DNA damage measured by γ-H2AX foci formation at a specified time point after 10 Gy irradiation,' by Zhang, et al. (2020-04-21)

Microbiome may hold key to identifying HPV-infected women at risk for pre-cancer
Gardnerella bacteria in the cervicovaginal microbiome may serve as a biomarker to identify women infected with human papillomavirus (HPV) who are at risk for progression to precancer, according to a study published March 26 in the open-access journal PLOS Pathogens by Robert Burk and Mykhaylo Usyk of the Albert Einstein College of Medicine, and colleagues. (2020-03-26)

The YAP signal plays a crucial role in head-and-neck cancer onset
Joint research between Kobe University and National Hospital Organization Kyushu Cancer Center has revealed that mice with mutations in the YAP signal pathway develop head-and-neck cancer over an extremely short period of time (world's fastest cancer onset mouse model), indicating that this pathway plays a crucial role in the onset of these cancers. This discovery may shed light on the development of new drugs for head-and-neck cancer. (2020-03-25)

Therapeutic HPV vaccine may improve outcomes in advanced cervical cancer
Combining a therapeutic vaccine for human papilloma virus (HPV) with two standard chemotherapy drugs may extend survival in patients with advanced, recurrent cervical cancer, according to a phase 1/2 trial involving 77 patients. (2020-03-18)

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