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Current Hpv News and Events, Hpv News Articles.
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HPV infections can be eliminated if both boys and girls are vaccinated
The human papillomavirus (HPV) causes, amongst other diseases, cancer of the cervix and oropharynx. A Swedish-Finnish study published in The Journal of Infectious Diseases now shows that the most oncogenic HPV types can be eliminated, but only if both girls and boys are vaccinated. Both genders will be offered vaccination in Sweden as of 2020. (2020-03-12)

Addressing HPV vaccination concerns
Research from the Harvard Pilgrim Health Care Institute finds a promising avenue for addressing vaccine hesitancy around HPV vaccine. The study, 'Tailored Messages Addressing HPV Vaccination Concerns Improves Behavioral Intent Among Mothers: A Randomized Controlled Trial,' appears March 11 in the Journal of Adolescent Health. (2020-03-11)

Immunosuppressive therapy for inflammatory bowel disease does not increase women's risk of vulvar or vaginal cancer
In a new retrospective study, researchers found that the use of immunosuppressive therapy does not increase the occurrence or recurrence of vulvar or vaginal cancer in women with inflammatory bowel disease (IBD). However, earlier onset of cancer was reported, and lymphomas were found in some patients, which is very rare in the genital tract. Their results appear in Digestive and Liver Disease, published by Elsevier. (2020-03-11)

Drug used for breast, kidney cancers may also extend survival for head and neck cancers
A targeted therapy drug used for breast and kidney cancers may also extend progression-free survival for patients with advanced head and neck cancer who are at high risk for recurrence after standard treatment. Patients enrolled in a randomized phase II trial who received the mTOR inhibitor everolimus were more likely to be cancer-free a year after therapy than those who took a placebo, and the benefit persisted for those with mutations in their TP53 gene. (2020-02-27)

HPV vaccine hesitancy in Japan could result in 5,000 additional death
The precipitous drop in HPV vaccination rates after suspension of proactive recommendations by the government in 2013 could result in an additional 25,000 cervical cancer cases and more than 5,000 additional deaths among females born between 1994 to 2007 in Japan. However, swift action by the government could mitigate much of this damage according to a study in Lancet Public Health. (2020-02-16)

Young men unaware of risks of HPV infection and need for HPV vaccination
Young sexual minority men -- including those who are gay, bisexual, queer or straight-identified men who have sex with men -- do not fully understand their risk for human papillomavirus (HPV) due to a lack of information from health care providers, according to Rutgers researchers. (2020-02-11)

Single HPV vaccine dose may be effective against cervical cancer
New research published in CANCER indicates that a single dose of the human papillomavirus (HPV) vaccine is as effective as multiple doses for preventing preinvasive cervical disease, which can later develop into cervical cancer. (2020-02-10)

Cervical cancer elimination possible within two decades in the US
At current levels of screening and HPV vaccination, cervical cancer incidence in the US is projected to fall below the threshold of elimination by 2038-2046. Scaling up screening coverage to 90% could expedite elimination timing by 10-13 years and avert an average of 1,400-2,088 additional cases per year. (2020-02-10)

Cervical cancer screening saves lives
Three-year interval in screening for cervical cancer is as effective as annual checkups, study finds. (2020-02-07)

Gaps in cure rate appear linked to race and insurance status for common HPV-related cancer
Largest population-based analysis to date on outcomes for HPV-positive oropharyngeal squamous cell carcinoma of the head and neck (SCCHN) finds significant racial and socioeconomic disparities, according to new research in JNCCN-Journal of the National Comprehensive Cancer Network. (2020-02-06)

Nimotuzumab-cisplatin-radiation versus cisplatin-radiation in HPV negative oropharyngeal cancer
Oncotarget Volume 11, Issue 4: In this study, locally advanced head and neck cancer patients undergoing definitive chemoradiation were randomly allocated to weekly cisplatin - radiation {CRT arm} or nimotuzumab -weekly cisplatin -radiation {NCRT arm}. (2020-02-06)

Viruses and cancer -- systematic overview published
Scientists from the German Cancer Research Center systematically investigated the DNA of more than 2,600 tumor samples from patients with 38 different types of cancer to discover traces of viruses -- which they found in 13% of the samples studied. The researchers also identified mechanisms that the pathogens use to trigger carcinogenic mutations in the DNA. The work is part of the Pan-Cancer Analysis of Whole Genomes (PCAWG). (2020-02-05)

First comprehensive survey of virus DNA found within cancer cells
Researchers have carried out the first comprehensive survey of viruses found within different types of cancer. An international team systematically investigated the DNA found within more than 2,600 tumor samples from patients with 38 different types of cancer. They discovered traces of viruses in 13% of the samples studied, and also further identified some of the mechanisms that viruses use to trigger carcinogenic mutations. (2020-02-05)

Cervical cancer could be eliminated within a century
Cervical cancer could be eliminated worldwide as a public health issue within the next century. This is the conclusion of two studies published today in The Lancet by an international consortium of researchers codirected by Professor Marc Brisson from Université Laval's Faculty of Medicine and the CHU de Québec-Université Laval Research Centre. The researchers are even more optimistic about North America, stating that the disease could be almost completely eliminated by 2040. (2020-01-30)

The Lancet: Cervical cancer could be eliminated in countries worst affected by the disease, and 62 million women's lives could be saved by 2120
Over the next 100 years, more than 74 million cervical cancer cases and 60 million deaths could be averted, and the disease eliminated in the 78 countries with the highest disease burden, according to two modelling studies published in The Lancet. (2020-01-30)

The virome of HPV-positive tonsil squamous cell carcinoma and neck metastasis
In this prospective study, a pan-pathogen microarray was used to determine the virome of early stage, p16-positive OPSCC and neck metastasis treated with transoral robotic surgery and neck dissection. (2020-01-27)

Doubts raised about effectiveness of HPV vaccines
A new analysis of the clinical trials of HPV vaccines to prevent cervical cancer raises doubts about the vaccines' effectiveness. The analysis, published by the Journal of the Royal Society of Medicine, assessed 12 published Phase 2 and 3 randomized controlled efficacy trials of the HPV vaccines Cervarix and Gardasil. (2020-01-21)

HPV status may affect risk of early death in patients with oropharynx cancer
New research published in CANCER indicates that there is a higher risk of early death among patients with oropharynx cancer when not caused by human papillomavirus (HPV), than those whose tumors are HPV-positive. (2020-01-13)

Correcting vaccine misinformation is a difficult process, study shows
Researchers found that vaccine misinformation in Danish media outlets from 2013-2016 led to HPV vaccinations dropping by 50.4%. An information campaign geared toward concerned parents helped increase vaccine uptake again, but uptake is still below the level before misinformation began, showing how difficult it is to undo the damages misinformation causes. (2020-01-07)

Women with single dose of HPV vaccine gain similar protection as multiple doses
A new study revealed that one dose of the HPV vaccine may prevent infection from the potential cancer-causing virus, according to research published in JAMA Network Open from The University of Texas Health Science Center at Houston (UTHealth). (2019-12-27)

Saliva test shows promise for earlier and easier detection of mouth and throat cancer
Unfortunately, cancers that occur in the back of the mouth and upper throat are often not diagnosed until they become advanced. A report in The Journal of Molecular Diagnostics describes the use of acoustofluidics, a new non-invasive method that analyzes saliva for the presence of human papilloma virus (HPV)-16, the pathogenic strain associated with oropharyngeal cancers (OPCs). This novel technique detected OPC in whole saliva in 40 percent of patients tested and 80% of confirmed OPC patients. (2019-12-13)

New Cochrane Review assesses different HPV vaccines & vaccine schedules in adolescent girls and boys
New evidence published in the Cochrane Library today provides further information on the benefits and harms of different human papillomavirus (HPV) vaccines and vaccine schedules in young women and men. (2019-11-22)

Trying to help parents decide to vaccinate kids against HPV? Consider storytelling
Health campaigns on social media aimed at increasing human papillomavirus (HPV) vaccination may see greater success, according to Drexel University researchers, if they inject a narrative into information-based posts. (2019-11-19)

Anal cancer rates and mortality have risen dramatically among Americans
Rates of new anal cancer diagnoses and deaths related to human papillomavirus (HPV), the most common sexually transmitted infection, have increased dramatically over the last 15 years, according to researchers at The University of Texas Health Science Center at Houston (UTHealth). The results of their study were published in the November issue of the Journal of the National Cancer Institute. (2019-11-19)

25 years of learning to combat cervical cancer
A recent paper from the lab of Professor Sudhir Krishna at the National Centre for Biological Sciences, Bangalore, reviews the progress made in cervical cancer research over the past 25 years. This extensive coverage published in the journal of Experimental Cell Research highlights the role of a popular signaling molecule called Notch in human cervical cancer progression. (2019-11-19)

Contraceptive drug shows promise for preventing and regressing cervical cancer
A new study in The American Journal of Pathology, published by Elsevier, reports that medroxyprogesterone acetate (MPA), the active ingredient in the common contraceptive injection Depo-Provera, was effective in preventing the development of cervical cancer in mice with precancerous lesions. The drug also decreased existing precancerous lesions. If proven effective clinically, MPA may be a boon to women who do not have access to human papillomavirus (HPV) vaccines. (2019-11-12)

CRISPR: More than just for gene editing?
Case Western Reserve University researchers have converted the CRISPR 'recognition induced enzymatic signal' to an electrical signal, which was then used to detect the biomarkers for viruses such as HPV or parvo. They hope the end result could be a new 'universal biosensing' point-of-care medical device -- similar to the existing commercial blood-glucose sensor -- that rapidly and accurately detects those viruses and more. (2019-11-11)

Cervical cancer screening numbers drop off in women 45-65
Virtually all cervical cancers are caused by HPV, and much of the attention in recent years has focused on preventing infections in younger women through HPV vaccination. But this may be taking attention off of another population that stands to benefit greatly from regular screening: women over 45. Despite the fact that half of cervical cancers are diagnosed after age 49, participation in preventive screening steadily declines between ages 45 and 65, according to a first-of-its-kind analysis of three large national surveys. (2019-11-07)

Randomized clinical trial focuses on mailed HPV self-sampling test kits
This randomized clinical trial compared mailed at-home HPV self-sampling test kits with the usual care reminders patients receive about in-clinic screening for increasing the detection and treatment of cervical precancers and screening. (2019-11-06)

Mailed self-sampling kits helped more women get screened for cervical cancer
Signaling a potential major change in cervical cancer screening options for American women, a new study found that mailed self-sampling kits that test for HPV -- the virus that can cause cervical cancer -- helped significantly more women get screened for the cancer. (2019-11-06)

Cervical pre-cancer can be detected in self-collected urine or vaginal samples
Researchers have developed a noninvasive test to detect cervical pre-cancer by analyzing urine and vaginal samples collected by the women themselves. The findings, presented at the NCRI Cancer Conference in Glasgow, could improve participation in screening programs. (2019-11-04)

Immune response against skin-dwelling viruses prevents cancer
Human papillomaviruses appear to play an unwitting role in protecting us against skin cancer according to a new study published in Nature. (2019-10-30)

Detection of oral HPV DNA in teen, young adult females
Researchers tested for HPV DNA in oral rinse samples collected over 10 years from a group of sexually active females (ages 13 to 21) who were planning to or had received the vaccine that targets four types of HPV. HPV was detected in 6.2% of 1,259 participants at baseline but oral HPV detection became less likely with time since becoming sexually active. (2019-10-25)

HPV immunization program cuts pre-cancer rates by more than half
A school-based human papillomavirus (HPV) immunization program in British Columbia, Canada, is dramatically reducing rates of cervical pre-cancer in B.C. women, according to a new study. (2019-10-21)

Scientists pioneer new way of finding cancer-causing germs
University of East Anglia scientists are pioneering a new way of finding cancer-causing germs. Some infections have already been linked with cancers including stomach cancer and cervical cancer. New research shows how genomic data collected from tumours could be sequenced to reveal other associated bacteria and viruses. (2019-10-21)

Assessment of circularized E7 RNA, GLUT1, and PD-L1 in anal squamous cell carcinoma
High levels of circ E7 by quantitative RT-PCR predicted improved overall survival in ASCC and analysis of The Cancer Genome Atlas sequencing from HPV-positive head and neck cancer and cervical cancer suggested high circ E7 marked improved survival in 875 subjects. (2019-10-16)

Microbes are a key marker of vaginal health during menopause
Certain species of bacteria are actually necessary to maintain vaginal health. The menopause transition, however, often upsets the natural balance of bacteria by decreasing the proportion of healthy bacteria and increasing vaginal pH. This can result in urogenital infections and other vaginal health problems. The importance of vaginal bacterial colonization patterns during menopause will be discussed at The North American Menopause Society (NAMS) Annual Meeting in Chicago, Sept. 25-28, 2019. (2019-09-24)

Physicians report high refusal rates for the HPV vaccine and need for improvement
Despite its proven success at preventing cancer, many adolescents are still not getting the HPV vaccine. A new study from the University of Colorado School of Medicine at the Anschutz Medical Campus shows that physicians' delivery and communication practices must improve to boost vaccination completion rates. (2019-09-16)

Most American adults do not know that HPV causes oral, anal, and penile cancers
More than 70% of US adults are unaware that human papillomavirus (HPV) causes anal, penile, and oral cancers, according to an analysis led by researchers at The University of Texas Health Science Center at Houston (UTHealth) School of Public Health and published in the current issue of JAMA Pediatrics. (2019-09-16)

Papillomaviruses may be able to be spread by blood
Researchers found that rabbit and mouse papillomaviruses could be transferred by blood to their respective hosts, raising the possibility that human papillomavirus (HPV) may also be transferable by blood in humans. (2019-09-11)

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